Acute Myeloid Leukemia

This page contains recent news articles, when available, and an overview of Acute Myeloid Leukemia but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

News: Acute Myeloid Leukemia

Bayer's Nexavar shows promise in acute myeloid leukemia - study  -  Jan 30, 2008
ForbesCHICAGO Thomson Financial - Bayer AG and Onyx Pharmaceutical's kidney cancer drug Nexavar has shown promising results in treating the most common and deadly ...

Donor cell-derived acute myeloid leukemia after unrelated umbilical...  -  Jan 26, 2006
Nature.comThe most frequent cause of treatment failure after allogeneic stem cell transplantation (SCT) for leukemia is relapse of the underlying host leukemia. ...

Donor Stem-Cell Transplant Best For Acute Myeloid Leukemia  -  Jun 9, 2009
ForbesTUESDAY, June 9 (HealthDay News) -- For most patients with acute myeloid leukemia (AML) who come out of remission, donor stem cells appear to offer the best ...

Genetic Changes May Dictate Course of Acute Myeloid Leukemia  -  Apr 30, 2008
Washington PostBy Amanda Gardner. WEDNESDAY, April 30 (HealthDay News) -- Breakthroughs in understanding the extremely fine genetic underpinnings of acute myeloid leukemia ...

A Look At The Disease That Killed CBS News' Ed Bradley  -  Nov 9, 2006
CBS NewsAcute myeloid leukemia: About 11930 new cases expected this year in the US; affects adults and children. Chronic myeloid leukemia: About 4600 new cases ...

… Receives FDA Orphan Drug Designation for Acute Myeloid Leukemia  -  Nov 5, 2009
MarketWatch...announced that the US Food and Drug Administration has granted voreloxin orphan drug designation for the treatment of acute myeloid leukemia (AML). ...

A rare case of acute myeloid leukemia with a CHIC2-ETV6 fusiongen and...  -  Oct 13, 2005
Nature.comCorrespondence: Dr F Kuchenbauer, Laboratory for Leukemia Diagnostics, Department of Medicine III, Klinikum Grosshadern, Ludwig-Maximilians University, ...

Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies  -  Dec 14, 2009
WebMDLeukemia and other diseases of the blood and bone marrow may affect red blood cells, white blood cells, and platelets. Normally, the bone marrow makes blood ...

Mother with acute myeloid leukemia seeks bone marrow donor  -  Nov 2, 2007
NEWS.com.auA MOTHER who is desperately searching for a matching bone marrow donor could be saved by a South Australian. Savita Taneja has a rare form of acute myeloid ...

… transplantation in patients with acute myeloid leukemia in first...  -  Mar 10, 2005
Nature.comAllogeneic hematopoietic stem-cell transplantation (allo-SCT) has an established role in the treatment of patients with acute myeloid leukemia (AML). ...

… in therapy-related acute myeloid leukemia with uncharacteristic...  -  Feb 14, 2008
Nature.comCorrespondence: Dr MT Andersen, Department of Clinical Genetics, Hematology/Oncology Section 4052, Rigshospitalet, Copenhagen University Hospital, ...

… long-term remission in refractory acute myeloid leukemia (AML)...  -  Jan 7, 2010
Nature.comSpontaneous remission of acute myeloid leukemia after infection and blood transfusion associated with hypergammaglobulinaemia. Ann Hematol 1996; 73: 189–193 ...

Immunophenotypic identification of acute myeloid leukemia with …  -  Apr 27, 2006
Nature.comIn 1976, the French-American-British (FAB) Cooperative Group published a morphologic classification of acute myeloid leukemia (AML). ...

… research findings offer hope of longer survival for acute myeloid...  -  Sep 23, 2009
Plain DealerAbout 12810 new cases of acute myeloid leukemia (AML) will be diagnosed in 2009 ... Traditionally, patients with a diagnosis of acute myeloid leukemia don't ...

… filgrastim (Pegfilgrastim) in patients with acute myeloid leukemia:...  -  Nov 22, 2007
Nature.comTo date, no data on pegfilgrastim in acute myeloid leukemia have been published. We report on our experience with this novel compound focusing on its ...

Nf1 gene inactivation in acute myeloid leukemia cells confers...  -  Nov 24, 2005
Nature.com1 Department of Genetics, Cell Biology and Development, The Cancer Center at the University of Minnesota, University of Minnesota, Minneapolis, MN, USA. ...

… of the TP53 gene in acute myeloid leukemia are strongly associated...  -  Jun 5, 2008
Nature.comCorrespondence: Dr C Haferlach, MLL Munich Leukemia Laboratory, Max-Lebsche-Platz 31, 81377 Munich, Germany. E-mail: claudia.haferlach@mll-online.com ...

Hyperdiploid karyotypes in acute myeloid leukemia define a novel...  -  Oct 11, 2007
Nature.comCorrespondence: Dr C Terre, Laboratoire de cytogénétique, Hôpital André Mignot, 177, rue de Versailles, Le Chesnay 78 150, France. ...

Pediatric acute myeloid leukemia: international progress and future …  -  Jul 28, 2005
Nature.comThe prognosis of pediatric acute myeloid leukemia (AML) has improved significantly over the past decades. However, few papers have actually illustrated this ...

Flow cytometric identification of acute myeloid leukemia with limited...  -  Apr 16, 2009
Nature.comMany specific leukemia subtypes have been identified by characteristic and reproducible phenotypic features detected mainly by cytomorphology and ...

… mutations in NOTCH1 in acute myeloid leukemia and lineage switch …  -  Sep 28, 2006
Nature.comCorrespondence: Dr AA Ferrando, Institute for Cancer Genetics, Columbia University, 1130 St Nicholas Avenue, Room 901B, New York, NY 10032, USA. ...

… frequent in patients with acute myeloid leukemia and complex...  -  Jul 3, 2008
Nature.comRisk-adapted therapy is now standard practice in acute myeloid leukemia (AML), ... Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in ...

Acute myeloid leukemia-targeted toxins kill tumor cells by cell type-...  -  Sep 20, 2007
Nature.comTargeted toxins are fusion proteins combining a targeting molecule that selectively recognizes and enters tumor cells through cell surface receptors with a ...

Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies  -  Apr 16, 2009
WebMDWhile the issues of long term complications of cancer and its treatment cross many disease categories, there are several important issues that relate to the ...

Detection of MOZ-CBP fusion in acute myeloid leukemia with 8;16 …  -  Sep 29, 2005
Nature.comCorrespondence: Dr Y Ning, Department of Pathology, Bldg. MSTF, Rm. 717, University of Maryland, 10 South Pine Street, Baltimore, MD 21201, USA. ...

… pedigree with familial acute myeloid leukemia and germline CEBPA …  -  Oct 23, 2008
Nature.comThe CCAAT enhancer-binding protein- (CEBPA) is a transcription factor strongly implicated in hematopoiesis through the control of proliferation and ...

… activating mutation in acute myeloid leukemia: prognostic impact...  -  Jun 21, 2007
Nature.comCharacterization of genetic aberrations in acute myeloid leukemia (AML) has ... JAK2 V617F is a rare finding in de novo acute myeloid leukemia, ...

… assessment of minimal residual disease in acute myeloid leukemia …  -  Mar 16, 2006
Nature.comMutations in nucleophosmin NPM1 in acute myeloid leukemia (AML): ... Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct ...

… therapy for children with acute myeloid leukemia: the children's...  -  Apr 14, 2005
Nature.comImproved treatment results in high-risk pediatric acute myeloid leukemia ... Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to ...

Two cell lines of t(8;21) acute myeloid leukemia with activating KIT...  -  Apr 3, 2008
Nature.comIn up to 30% of acute myeloid leukemia (AML), chromosomal translocations disrupt one of the core binding factor (CBF) genes most frequently by the t(8 ...

Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies  -  Mar 26, 2009
WebMDThere are different types of treatment for children with acute myeloid leukemia (AML), chronic myelogenous leukemia (CML), juvenile myelomonocytic leukemia ...

… response to lenalidomide monotherapy in acute myeloid leukemia …  -  Sep 21, 2006
Nature.com2 However, no data exist regarding the efficacy of lenalidomide in patients with del(5)(q13q33) who have progressed to acute myeloid leukemia (AML). ...

Successive clinical trials for childhood acute myeloid leukemia at St...  -  Nov 10, 2005
Nature.comCorrespondence: Dr RC Ribeiro, International Outreach Program, Department of Hematology-Oncology, St Jude Children's Research Hospital, 332 North Lauderdale ...

Treatment of relapsed acute myeloid leukemia with MLL/AF6 fusion...  -  Nov 8, 2007
Nature.comThe treatment options available in cases of relapsed acute myeloid leukemia (AML) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) are ...

Adult Acute Myeloid Leukemia  -  Dec 14, 2009
WebMDAdvances in the treatment of AML (also called acute myelogenous leukemia, acute nonlymphocytic leukemia, or ANLL) have resulted in substantially improved ...

Characterization of acute myeloid leukemia with PTPN11 mutation: the ...  -  Feb 1, 2008
Nature.comAcute myeloid leukemia (AML) is a relentless hematological malignancy characterized by overproduction of hematopoietic precursor cells with impaired ...

… in a case of acute myeloid leukemia transformed from myelodysplasti...  -  Oct 19, 2006
Nature.comMyeloblasts and promyelocytes were increased to 28.5%, consistent with myelodysplastic syndrome progression to acute myeloid leukemia. ...

Expression of BEX1 in acute myeloid leukemia with MLL rearrangements  -  May 26, 2005
Nature.comCorrespondence: Dr H Quentmeier, DSMZ - German Collection of Microorganisms and Cell Cultures, Mascheroder Weg 1 B, D-38124 Braunschweig, Germany. ...

Human acute myeloid leukemia is organized as a hierarchy that …  -  Sep 27, 2007
Nature.comOncology researchers have embraced the notion of cancer stem cells (CSCs): certain tumour cells, it seems, are more equal than others. ...

Cytogenetic profile of de novo acute myeloid leukemia: a study based...  -  May 28, 2009
Nature.comCorrespondence: Professor J Jin, Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, No. ...

Adult Acute Myeloid Leukemia  -  Sep 25, 2008
WebMDImmunophenotyping reveals blasts that express at least two myelomonocytic antigens (CD13, CD33, CD117) and/or MPO. CD34 is often positive. ...

… therapy in patients 61 years or older with acute myeloid leukemia  -  Jan 26, 2006
Nature.comIn patients over the age of 60 years with acute myeloid leukemia (AML), ... Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older ...

EpiCept Announces Commercial Licensing Agreement for Ceplene(R) …  -  Jan 11, 2010
Wall Street JournalCeplene is indicated for remission maintenance therapy and prevention of relapse in adult patients with Acute Myeloid Leukemia (AML). ...

… in older adults with acute myeloid leukemia: predictors and...  -  Feb 8, 2007
Nature.comFatigue is the most common, distressing, and persistent symptom in patients with cancer, 1 present in 60–96% of patients with various malignancies. ...

… cytarabine is effective for childhood acute myeloid leukemia:...  -  Feb 26, 2009
Nature.comRecent trials for childhood acute myeloid leukemia (AML) have attempted to ... Kaspers GJ, Creutzig U. Pediatric acute myeloid leukemia: international ...

Adult Acute Myeloid Leukemia  -  Aug 7, 2008
WebMDDifferent types of treatment are available for patients with adult acute myeloid leukemia (AML). Some treatments are standard (the currently used treatment) ...

Antibody–drug conjugates in acute myeloid leukemia  -  Jan 10, 2006
Nature.comLarson RA et al. (2005) Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in ...

New drug hits leukemia early  -  Jan 10, 2010
Science NewsThis and other studies have paved the way for preliminary testing of a version of the drug for people with acute myeloid leukemia, a particularly lethal ...

… of patients with acute myeloid leukemia or myelodysplastic...  -  Oct 12, 2009
Nature.comLong-term survival in refractory acute myeloid leukemia after sequential ... Induction of complete remission in a patient with acute myeloid leukemia ...

… stem cell transplantation for therapy-related acute myeloid...  -  Feb 26, 2007
Nature.com...of autologous stem cell transplantation in patients with therapy-related myelodysplastic syndrome (t-MDS)/therapy-related acute myeloid leukemia (t-AML) ...

Is BAL useful in patients with acute myeloid leukemia admitted in ICU...  -  Apr 24, 2008
Nature.comCorrespondence: Dr A Rabbat, Department of Respiratory and Critical Care Medicine, Hôpital Hôtel Dieu, University Paris Descartes, 1 place du parvis Notre ...

Clinical and biological features of favorable-risk acute myelogenous ...  -  Feb 3, 2005
Nature.comRisk-adapted postremission therapy in acute myeloid leukemia: results of the ... CEBPA mutations in younger adults with acute myeloid leukemia and normal ...

… during therapy in acute myeloid leukemia: biological and clinical...  -  Sep 21, 2006
Nature.comMolecular biology is a powerful tool for investigating acute myeloid leukemia (AML). Given that concerted efforts have documented the reliability and ...

Outcome after allogeneic transplantation for adult acute myeloid...  -  Apr 6, 2009
Nature.comLowenberg B, Downing JR, Burnett A. Acute myeloid leukemia. ... Acute Myeloid Leukemia: Biologic and genetic risk assessment of AML in the genomic era by ...

EpiCept Announces Ceplene(R) Included in Swedish AML Medical …  -  Jan 26, 2010
FOXBusinessCeplene plus low-dose interleukin (IL-2) is indicated for remission maintenance and prevention of relapse in adult patients with Acute Myeloid Leukemia ...

A case of therapy-related acute myeloid leukemia associated with...  -  Jan 26, 2006
Nature.com2 Division of Hematology, Department of Internal-Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. E-mail: yonggoo@catholic.ac. ...

Acute Myeloid Leukemia; New findings in acute myeloid leukemia …  -  Jun 16, 2005
Pay-Per-View - Gene Therapy Weekly - Factiva, from Dow Jones2005 JUN 16 - (NewsRx.com) -- Data on acute myeloid leukemia are outlined in reports from Taiwan, the United States and Germany. ...

… an activating TEK mutation in acute myeloid leukemia: a cellular...  -  Apr 2, 2009
Nature.com5 One malignancy in which tyrosine kinases are abnormally regulated is acute myeloid leukemia (AML). Several reports have shown that signal transducer and ...

High-throughput mutational screen of the tyrosine kinome in chronic …  -  Jul 10, 2008
Nature.com3, 4 NF-1 (neurofibromatosis 1) has not been studied extensively, but one study of patients with MDS (including CMML) and acute myeloid leukemia did not ...

Myeloid leukemia in children 4 years or older with Down syndrome...  -  Dec 6, 2007
Nature.comDistinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's cancer group ...

Targeting the most critical cells: approaching leukemia therapy as a ...  -  Feb 8, 2005
Nature.com...(2003) Human acute myeloid leukemia stem cells. ... (2003) Survival of acute myeloid leukemia cells requires PI3 kinase activation. ...

Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies  -  Apr 16, 2009
WebMDJuvenile myelomonocytic leukemia (JMML), formerly termed juvenile chronic myeloid leukemia, is a rare hematopoietic malignancy of childhood accounting for ...

… induction therapy in patients 70 years with acute myeloid leukemia  -  Mar 8, 2007
Nature.comAttempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: ... Age and acute myeloid leukemia. Blood 2006; 107: 3481–3485. ...

Adult Acute Myeloid Leukemia  -  Sep 25, 2008
WebMDBecause bone marrow transplantation can cure about 30% of patients who experience relapse following chemotherapy, some investigators suggested that ...

Acute Myeloid Leukemia (AML) – Drug Pipeline Analysis and Market …  -  Jan 6, 2010
PR UrgentGlobalData has estimated the global AML therapeutics market to be valued at $174m in 2009. It is expected to grow to $329m with a Compound Annual Growth ...

Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies  -  Dec 14, 2009
WebMDThe National Cancer Institute (NCI) provides the PDQ pediatric cancer treatment information summaries as a public service to increase the availability of ...

The size of duplication does not add to the prognostic significance...  -  Aug 31, 2006
Nature.com1 Tandem internal duplication of the FLT3 gene (FLT3/ITDs) represents one of the most common molecular abnormalities in patients with acute myeloid leukemia ...

New test for targeted therapy in acute myeloid leukemia  -  Dec 10, 2007
News-Medical.netOregon Health & Science University Cancer Institute researcher Jeff Tyner, Ph.D., has created a way to identify proteins that are candidates for targeted ...

… Orphan Drug Designation in Europe for Acute Myeloid Leukemia.  -  Mar 9, 2005
Free with registration - Business Wire - AccessMyLibrary.com..."The granting of orphan drug status of Ceplene for the treatment of acute myeloid leukemia patients in complete remission recognizes the need for new ...

New study backs solvent, leukemia link  -  Nov 18, 2008
Reuters UKIt is understood to cause acute myeloid leukemia, but its association with multiple ... There was no association between acute myeloid leukemia and benzene, ...

Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies …  -  Apr 16, 2009
WebMDDespite second remission induction in over one-half of children with acute myeloid leukemia (AML) treated with drugs similar to drugs used in initial ...

… Enrollment of Voreloxin REVEAL-1 Trial in Acute Myeloid Leukemia  -  Oct 30, 2009
Bizjournals.com...agent voreloxin in newly diagnosed elderly acute myeloid leukemia (AML) patients who are unlikely to benefit from standard induction chemotherapy. ...

Cyclacel Reports Phase 2 Sapacitabine Data in Acute Myeloid Leukemia ...  -  Dec 5, 2009
CNNMoney.com...nucleoside analogue, in elderly patients with acute myeloid leukemia (AML) and separately interim response data in myelodysplastic syndromes (MDS). ...

Faced with acute myeloid leukemia, her hobby helped  -  Jun 20, 2006
Press-EnterpriseBy CLAUDIA BUSTAMANTE. MURRIETA - At the back of Laura James' Murrieta home is a room that glows in the afternoon sun with green walls, rolls of ribbon, ...

Acute myeloid leukemia.  -  May 1, 2007
Free with registration - CareNotes - AccessMyLibrary.comWhat is it? Acute myeloid leukemia (loo-KEE-mee-ah) is also called acute myelogenous (mi-e-LOJ-e-nus) leukemia or AML. It is a fast-growing cancer of the ...

Kidney Cancer Drug Attacks A Major Type Of Acute Myeloid Leukemia  -  Feb 1, 2008
sciencedaily.comScienceDaily (Feb. 1, 2008) — A drug used to treat kidney cancer also targets a genetic mutation active in about one third of patients with acute myeloid ...

FDA criticizes Genzyme study of leukemia drug  -  Aug 29, 2009
Boston Globe21 for older patients with acute myeloid leukemia. The company and the FDA are scheduled to present their findings Tuesday to an outside panel of ...

Acute myeloid leukemias with recurrent genetic abnormalities:...  -  Mar 3, 2005
Nature.comThe majority of patients with acute myeloid leukemia (AML) achieve complete remission after induction and consolidation therapy. ...

… Supports Ceflatonin(R) in Treatment of Acute Myeloid Leukemia (AML)  -  Mar 22, 2006
RedOrbitChemGenex is developing Ceflatonin for the treatment of CML, myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). ChemGenex Pharmaceuticals is a ...

Doubling chemo dose helped leukemia patients  -  Sep 23, 2009
msnbc.comAcute myeloid leukemia is a cancer of the blood and bone marrow. It's the most common type of acute leukemia in adults. About 12810 new cases will be ...

Leukemia cells rely on fatty acid metabolism to grow and evade cell...  -  Jan 28, 2010
News-Medical.netAdditionally, etomoxir was found to decrease the number of quiescent leukemia progenitor cells in half of blood samples taken from acute myeloid leukemia ...

… stem cell transplantation for patients with acute myeloid leukemia:...  -  Jun 26, 2008
Nature.comReduced-intensity conditioning for acute myeloid leukemia: is this strategy correct. ... Sustained remissions of high-risk acute myeloid leukemia and ...

Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies  -  Apr 16, 2009
WebMDSide effects of cancer treatment, management of cancer-related complications and pain, and psychosocial concerns. Tests or procedures that detect specific ...

Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies  -  Apr 16, 2009
WebMDAPL in children is generally similar to APL in adults, though children have a higher incidence of hyperleukocytosis (defined as white blood cell [WBC] count ...

MicroRNA expression profiles of human leukemias  -  Nov 8, 2007
Nature.comHsj_ 376 was found in two acute myeloid leukemia samples (corresponding to a total of 52 ... ALL, acute myeloid leukemia; AML, acute lymphoid leukemia; MDS, ...

Is there a role for postremission therapy in older adults with acute ...  -  Jun 9, 2005
Nature.comVarying intensity of postremission therapy in acute myeloid leukemia. ... Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older ...

Managing Acute Myeloid Leukemia in the Elderly  -  Nov 17, 2006
Cancer NetworkAcute myeloid leukemia (AML) is a disease of the elderly, with the majority of patients diagnosed in their 6th and 7th decade of life. ...

Data from Three Phase II Trials to be Presented at the 51st American ...  -  Dec 7, 2009
Wall Street JournalAcute myeloid leukemia (AML), also known as acute myelogenous leukemia, is characterized by the rapid growth of abnormal white blood cells of the myeloid ...

Outcome after reduced-intensity conditioning allogeneic SCT for AML...  -  Aug 4, 2008
Nature.comReduced-intensity conditioning for acute myeloid leukemia: is this strategy correct. ... Sustained remissions of high-risk acute myeloid leukemia and ...

A comparison of the outcomes of children with acute myelogenous …  -  Feb 11, 2008
Nature.comOutcome for children with relapsed acute myeloid leukemia following initial ... Unrelated donor marrow transplantation for acute myeloid leukemia: an update ...

Mutational analysis of candidate tumor-associated genes in acute …  -  Aug 6, 2009
Nature.comThe incidence of AMKL in adult de novo acute myeloid leukemia patients is estimated to be ... Acute myeloid leukemia and Down syndrome evolution of modern ...

… of minimal residual disease in patients with acute myeloid...  -  Oct 2, 2008
Nature.comAcute myeloid leukemia (AML) is a clinically and cytogenetically heterogeneous disease in ... Nucleophosmin mutations in de novo acute myeloid leukemia: the ...

Targeting stem cells suggests way to cure leukemia, mice study shows  -  Sep 25, 2006
CBC.caDr. Donna Hogge, a leukemia specialist and researcher at the BC Cancer Research Centre, said there are many types of acute myeloid leukemia, and the disease ...

… and outcomes in patients with t(8;21) acute myeloid leukemia in...  -  Aug 16, 2007
Nature.comPatients with t(8;21)(q22;q22) and acute myeloid leukemia have superior ... Characteristics of t(8;21) acute myeloid leukemia (AML) with additional ...

Ashley's still swinging: 'The cancer doesn't have me'  -  Feb 5, 2010
Seattle Post-Intelligencer - Seattle Post IntelligencerAshley, 17 years-old and a softball player at Meadowdale High School, is battling acute myeloid leukemia, a rare and aggressive disease. ...

New Drug Could Work Against Leukemia  -  Jul 2, 2009
ABC NewsLSCs are cells that can cause acute myeloid leukemia (AML) and are critical for its long-term growth. When AML-LSCs from human patients were transplanted ...

Acute Myeloid Leukemia - Identification Of The Genetic Alteration …  -  Dec 19, 2005
Medical News Today - Medical News Today (press release)At the Institut Curie, an Inserm team has just identified the molecular mechanism long suspected to account for the formation of malignant cells in the most ...

Genzyme seeks FDA approval to treat adult leukemia  -  Nov 24, 2008
Bizjournals.comGenzyme (NASDAQ: GENZ) is developing the drug for the treatment of adult acute myeloid leukemia, pediatric acute lymphoblastic leukemia and myelodysplastic ...

… CD34+ cells from patients with acute myeloid leukemia after gene...  -  Jan 15, 2009
Nature.comAcute myeloid leukemia (AML) is a malignant disease characterized by ... Reduced proliferation of CD34 + acute myeloid leukemia (AML) cells after treatment ...

High incidence of acute promyelocytic leukemia in children in...  -  Sep 13, 2007
Nature.comAcute myeloid leukemia (AML) represents approximately 20% of acute leukemia in children (0–14 years old) 1 and is divided into subgroups based on the ...



Background information on Acute Myeloid Leukemia [When available]

Acute myelogenous leukemia (AML), also known as acute myeloid leukemia, is a cancer of the myeloid line of blood cells. It is the most commonly diagnosed type of adult leukemia, and is rare among children.

These malignant cells called myeloblasts fail to mature into the different types of blood cells, a process called differentiation. If differentiation does not occur, the myeloblasts accumulate and overtake the number of healthy blood cells, spreading into the bloodstream and other vital organs. The lack of healthy blood cells results in symptoms such as anaemia and abnormal bruising.

Myeloid leukemias are characterized as "acute" or "chronic" based on how quickly they progress if not treated. Chronic myelogenous leukemia (CML) is often without symptoms and can remain dormant for years before transforming into a blast crisis, which is markedly similar to AML.

Search the web for more resources on Acute Myeloid Leukemia



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