Paraganglioma

This page contains recent news articles, when available, and an overview of Paraganglioma but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

News: Paraganglioma

A case of familial paraganglioma syndrome type 4 caused by a mutation...  -  Mar 1, 2006
Nature.comBackground A 40-year-old man was referred to our clinic with recurrent paragangliomas. He had undergone resection of a paraganglioma superior to the right ...

A case of familial paraganglioma syndrome type 4 caused by a mutation...  -  Mar 1, 2006
Nature.comBackground A 40-year-old man was referred to our clinic with recurrent paragangliomas. He had undergone resection of a paraganglioma superior to the right ...

Molecular Insight Pharmaceuticals Presents Azedra(TM) 12-Month …  -  Oct 5, 2009
Wall Street JournalSince hypertension typically occurs in more than 90 percent of pheochromocytoma/paraganglioma patients, changes in anti-hypertensive medication from ...

… , neonatal renal mesoblastic nephroma and pararenal paraganglioma  -  Apr 6, 2009
Nature.comSympathetic paraganglioma is usually a benign tumor arising from ... Although we are unaware of any case of a simultaneous paraganglioma and MN, ...

Black cardiac paraganglioma in a multiple paraganglioma syndrome  -  Jun 28, 2007
European Journal of Cardio-Thoracic......* Corresponding author. Address: Dipartimento del Cuore e Grossi Vasi "Attilio Reale", Policlinico Umberto I. Viale del Policlinico 155, 00161 Rome, Italy. ...

Paraganglioma—All in the Family  -  Dec 19, 2005
Journal of Clinical Endocrinology and...Division of Endocrinology, Diabetes, Metabolism, and Nutrition (WFY), Mayo Clinic, Rochester, Minnesota 55905; and Public Health Laboratory, ...

Funny, loving side of Sydney's crime king  -  Jan 30, 2007
Sydney Morning HeraldHe had been awaiting trial in Long Bay jail when he died from the rare cancer metastatic paraganglioma. By 11.30am today those willing to take the Eucharist ...

Metastatic Paraganglioma: An Uncommon Manifestation of an …  -  Mar 1, 2008
Cancer NetworkBy Jay S. Cooper, MD. Nevertheless, after reading only the beginning of the report, a squamous cell carcinoma of the head and neck (perhaps an asymptomatic ...

Paraganglioma Syndrome and Mutations of the SDHC Gene  -  Feb 8, 2006
Journal of American Medical Association - Journal of American Medical Association...To the Editor: In their study of paraganglioma syndrome associated with mutations in the SDHC gene, Dr Schiavi and colleagues 1 have incompletely reviewed ...

Head and Neck Paragangliomas: Value of Contrast-Enhanced 3D MR …  -  Mar 13, 2008
AJNR (subscription)The overall image quality and the probability of paraganglioma were recorded. ... Two patients had a jugulotympanic paraganglioma, which had a typical ...

… , Tyr3]Octreotate in Patients with Paraganglioma, Meningioma, Small...  -  Aug 1, 2008
Journal of Nuclear Medicine (subscriptio...Results: Two of 4 patients with progressive paraganglioma had tumor regression and 1 had ... Of 5 patients with stable paraganglioma, 2 had SD, 2 had PD, ...

Paraganglioma of the left atrium  -  Feb 1, 2009
Journal of Thoracic and Cardiovascular... - The Journal of Thoracic and Cardiovascul...KMJohn Chan, AFRCS, David Pontefract, MRCS, Richard Andrews, MRCP, Surendra K. Naik, PhD, FRCS (CTh), Nottingham, United Kingdom ...

Functioning Thoracic Paraganglioma: Association with Von Hippel- …  -  Dec 1, 2007
Journal of Clinical Endocrinology and...Bernhard U. Bender, Carsten Altehöfer, Andrzej Januszewicz, Roland Gärtner, Heinrich Schmidt, Michael M. Hoffmann, Peter H. Heidemann and Hartmut PH Neumann ...

Paraganglioma of the hepatic duct: a personal commentary.(Letters to...  -  Jul 1, 2006
$4.95 - Southern Medical Journal - ECNextTo the Editor: In 1980, we reported a case of paraganglioma of the hepatic duct in a 37-year-old man. (1) At that time, we claimed that our case was the ...

West Midlands News Woman nearly moved to NHS while dying  -  Aug 23, 2005
Birmingham Post - The Birmingham PostPathologist Dr Henry Thompson said it was first believed the lump had been an enlarged lymph node but it was subsequently discovered to be a paraganglioma, ...

Pigmented 'black' cardiac paraganglioma in a patient with a novel...  -  Aug 6, 2008
European Journal of Cardio-Thoracic......* Corresponding author. Address: Department of Clinical Sciences, University of Rome 'La Sapienza', Policlinico 'Umberto I', Viale del Policlinico, 155, ...

Genetics of pheochromocytoma and paraganglioma in Spanish patients  -  Feb 23, 2009
Journal of Clinical Endocrinology and...Context: The presence of familial history in pheochromocytoma/paraganglioma patients, including syndromic antecedents, leads in the majority of cases to a ...

Paraganglioma of the cauda equina: A case report and literature...  -  Apr 1, 2005
Subscription - Surgeon - EBSCO PublishingCase Report Paraganglioma of the cauda equina: A case report and literature review Paraganglioma of the cauda equina: A case report and literature review A ...

Predictors and Prevalence of Paraganglioma Syndrome Associated With …  -  Feb 8, 2006
Journal of American Medical Association - Journal of American Medical Association...Incorrect Reference: In the Original Contribution entitled "Predictors and Prevalence of Paraganglioma Syndrome Associated With Mutations of the SDHC Gene" ...

EBSCOhost Connection: Malignant Paraganglioma of The Nose.  -  Jan 6, 2007
Subscription - Internet Journal of Otorhinolaryngology - EBSCO PublishingMalignant Paraganglioma of The Nose Malignant Paraganglioma of The Nose Paragangliomas of the head and neck are uncommon tumors in head and neck area. ...

Paraganglioma after maternal transmission of a succinate …  -  Jan 14, 2008
Journal of Clinical Endocrinology and...Context: Inactivating mutations of SDHD, which is mapped to 11q23 and encodes the cybS subunit of succinate dehydrogenase, predispose to hereditary ...

A 25-year-old woman with a gastric GIST and a PET-positive epicardial...  -  Aug 25, 2006
Nature.comDiagnosis Gastrointestinal stromal tumor, epicardial paraganglioma, and Carney's ... The patient had no family history of paraganglioma or gastrointestinal ...

Paraganglioma: A Potentially Challenging Tumor  -  Mar 1, 2008
Cancer NetworkAs noted earlier, paragangliomas are usually low-grade neoplasms with a benign natural history. The largest clusters of these neuroectodermal cells occur in ...

Pheochromocytoma and paraganglioma in children: a review of medical …  -  Sep 1, 2006
$4.95 - Pediatrics - ECNextPHEOCHROMOCYTOMA AND PARAGANGLIOMA are exceptionally rare neoplasms in children. Both tumors develop from neural crest cell lineage, stain positive for ...

Extra-adrenal and adrenal pheochromocytomas associated with a …  -  Jun 12, 2007
Nature.com3 For practical purposes, however, we use the term 'paraganglioma' for tumors ... Data from the European–American Pheochromocytoma–Paraganglioma Registry. ...

Paraganglioma Syndrome and Mutations of the SDHC Gene—Reply  -  Feb 8, 2006
Journal of American Medical Association - Journal of American Medical Association...In Reply: We thank Dr Niemann for pointing out the citation errors in our tables. The definitions of malignant disease for pheochromocytoma and ...

… perioperative management of a middle mediastinal paraganglioma  -  Jan 23, 2006
Journal of Thoracic and Cardiovascular... - The Journal of Thoracic and Cardiovascul......* Address for reprints: Jun Matsumoto, MD, Division of Surgery, Asahi General Hospital, I-1326 Asahi, Chiba, Japan (Email: ...

Pitfalls in imaging: differentiating intravagal and carotid body …  -  Jun 1, 2005
Free with registration - Ear, Nose and Throat Journal - AccessMyLibrary.comWe report a case of an intravagal paraganglioma and a case of a carotid body ... The atypical imaging features of the intravagal paraganglioma included ...

… in a woman with epithelial thyroid cancer and carotid paraganglioma...  -  Jan 29, 2007
Nature.comTwo years later, she was diagnosed with a paraganglioma of the right carotid body. ... The mass was resected, and pathology revealed a paraganglioma with a ...

The genetic basis of pheochromocytoma: who to screen and how?  -  Sep 16, 2005
Nature.com...(2005) Genetic testing in pheochromocytoma or functional paraganglioma. ... (2004) Distinct clinical features of paraganglioma syndromes associated with ...

… Paraganglioma; Cervical paraganglioma-related neurological...  -  Oct 3, 2006
Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones2006 OCT 3 - (NewsRx.com) -- Progressive neurological deficits in patients with cervical paraganglioma might be prevented by early management. ...

Paraganglioma; Scientists at Tohoku University, Department of...  -  Dec 19, 2006
Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones2006 DEC 19 - (NewsRx.com) -- A report, "A novel G106D alteration of the SDHD gene in a pedigree with familial paraganglioma," is newly published data in ...

An Extra-adrenal Abdominal Pheochromocytoma Causing Ectopic ACTH …  -  Oct 1, 2005
Nature.comAfter surgical removal of the paraganglioma, the patient's clinical symptoms improved ... Culture of primary cells collected from the resected paraganglioma ...

Functional paragangliomas presenting as primary liver tumors.(Brief …  -  Feb 1, 2007
$4.95 - Southern Medical Journal - ECNextFinally, if there is suspicion that the lesion is a paraganglioma or pheochromocytoma ... Primary paraganglioma strictly confined to the liver and mimicking ...

Undifferentiated metastatic carcinoma and myoepithelioma: two rare …  -  Jul 1, 2007
Free with registration - Ear, Nose and Throat Journal - AccessMyLibrary.comThe classic presentation of the most common paraganglioma of the parapharyngeal ... (15) A paraganglioma is a likely cause of a vascular lesion of the ...

Genetic testing in pheochromocytoma  -  Oct 8, 2009
Endocrine TodayFamilial paraganglioma is an autosomal disorder due to mutations in the ... Which individuals with pheochromocytoma/paraganglioma should be tested for ...

Cancer's insatiable appetite  -  Mar 13, 2008
Nature.comAll mutations known to cause hereditary paraganglioma therefore lead to altered gene expression that drives glucose uptake and metabolism and promotes ...

New Jersey Administrative Code - 8:57A-1.8 List of reportable...  -  Aug 16, 2005
Pay-Per-View - New Jersey Administrative Code - LoislawADRENAL Adrenal cortical carcinoma Ganglioneuroblastoma Neuroblastoma Neuroendocrine carcinoma Neuroepithelioma Paraganglioma (+) Pheochromocytoma, ...

Undifferentiated metastatic carcinoma and myoepithelioma: two rare …  -  Jul 1, 2007
$4.95 - Ear, Nose and Throat Journal - ECNextThe classic presentation of the most common paraganglioma of the parapharyngeal ... (15) A paraganglioma is a likely cause of a vascular lesion of the ...

Also in the Aug. 26 JNCI  -  Aug 26, 2008
eurekalert.org...genes were principally associated with the development of pheochromocytoma or paraganglioma, which are tumor syndromes that affect other tissues. ...

Extra-adrenal pheochromocytoma involving the left atrium: An infrequen...  -  Jun 16, 2006
Journal of Thoracic and Cardiovascular... - The Journal of Thoracic and Cardiovascul...1 This subset of paraganglioma might require special surgical management techniques, ... 3 In our case the aortopulmonary paraganglioma arises from the ...

Also in the Aug. 26 JNCI  -  Aug 29, 2008
Eureka! Science News...genes were principally associated with the development of pheochromocytoma or paraganglioma, which are tumor syndromes that affect other tissues. ...

Clear cell sarcoma of tendons and aponeuroses: a review.  -  Jan 1, 2007
Free with registration - Archives of Pathology & Laboratory... - AccessMyLibrary.comIn contrast to CCSTA, paraganglioma-like dermal melanocytic tumor is primarily a tumor of the extremities of females, presents as a dermal nodule, ...

Nevada Administrative Code - NAC 457.040 Types of malignant …  -  Aug 11, 2005
Pay-Per-View - Nevada Administrative Code - LoislawParagangliomas and glomus tumors: Paraganglioma, malignant Extra-adrenal paraganglioma, malignant Nonchromaffin paraganglioma, malignant Pheochromocytoma, ...

Thoracic extradural paragangliomas: a case report and review of the …  -  Aug 30, 2005
Nature.comTo report on a case of paraganglioma presenting in an uncommon extradural thoracic localization. A 43-year-old woman with a thoracic lesion extending into ...

Press Release: Molecular Insight Pharmaceuticals, Inc. To Present...  -  May 19, 2008
Pay-Per-View - M2 Presswire - HighBeam ResearchMolecular Insight Pharmaceuticals, Inc. To Present Interim Phase 1 Data at ASCO on Azedra(TM) in Malignant Pheochromocytoma/Paraganglioma Patients. from M2 ...

Mujer de 21 años embarazada con hipertensión y proteinuria  -  Apr 22, 2009
Intramed.net - Intramed.net (Suscripción)Los pacientes con feocromocitoma o paraganglioma deben ser controlados por el resto de sus vidas, ya que la tasa de recidiva a los 5 años oscila entre el 2 ...

British Journal of Cancer - Assessment of the efficacy and toxicity...  -  Feb 19, 2008
Nature.comThe remainder had other tumour types (mostly paraganglioma, phaeochromocytoma, and medullary carcinoma of the thyroid) and were excluded from further ...

Fundraiser set for local cancer patient  -  Aug 28, 2009
Banner-Graphic - The Banner-GraphicJanella Edwards Whittaker of Greencastle has suffered from Paraganglioma -- tumors ... Buchanan said that Paraganglioma is a "recurring disease," and that ...

NATURAL GENETIC MUTATION MAY HELP BEAT SOME CANCERS  -  May 10, 2007
$2.95 - Pittsburgh Post-Gazette - NewsBankBut the same mutation also causes a rare form of cancer known as paraganglioma and might help other cancers survive longer with less oxygen. ...

Factiva Search  -  Mar 28, 2006
Pay-Per-View - Life Science Weekly - Factiva, from Dow JonesParagangliomas; Patient with paraganglioma of Zuckerkandl and carotid body ... 2006 MAR 28 - (NewsRx.com) -- A patient who presented with paraganglioma of ...

Should Patients with Apparently Sporadic Pheochromocytomas or …  -  Feb 1, 2009
Journal of Clinical Endocrinology and...Context: The recent identification of germline mutations of the mitochondrial complex II genes in variants of paraganglioma/pheochromocytoma syndrome has ...

Modern management of pheochromocytoma  -  Dec 1, 2007
Nature.com...(2005) Year of diagnosis, features at presentation, and risk of recurrence in patients with pheochromocytoma or secreting paraganglioma. ...

Oncocytoma of the spinal cord causing paraplegia – a case report  -  Feb 28, 2006
Nature.comParaganglioma can be differentiated by its distinctive trabecular or organoid pattern, the immunoreactivity for S-100 protein and chromogranin, ...

Molecular Insight Pharmaceuticals, Inc. To Present Interim Phase 1...  -  May 16, 2008
RedOrbit...with malignant pheochromocytoma/paraganglioma. The trial is part of the company's program to develop Azedra for the treatment of neuroendocrine cancers. ...

Errant inmate's time increased to 20 years  -  Oct 29, 2008
Marshall County TribuneAn Indiana doctor said he was treated for paraganglioma nearly three years ago. A review of Internet sites indicates that paraganglioma usually includes ...

Glomus tympanicum.(OTOSCOPIC CLINIC)(Disease/Disorder overview)  -  Jun 1, 2007
Free with registration - Ear, Nose and Throat Journal - AccessMyLibrary.comGlomus tympanicum is an uncommon paraganglioma that arises from the promontory of the cochlea. The blood is supplied by the inferior tympanic branch of the ...

3 local families discover true meaning of Thanksgiving  -  Nov 26, 2008
Cherokeean Herald - The Cherokeean HeraldThis past summer, Joshua Ward was diagnosed with paraganglioma, ... However, due to the rare nature of paraganglioma, few doctors in the area were able to ...

Should Patients with Apparently Sporadic Pheochromocytomas or …  -  May 18, 2006
Journal of Clinical Endocrinology and...Context: The recent identification of germline mutations of the mitochondrial complex II genes in variants of paraganglioma/pheochromocytoma syndrome has ...

Atlanta Doc to Help Ailing Ghanese Girl  -  Jan 29, 2010
MyFox AtlantaDoctors say she has a paraganglioma tumor that is now growing on both her jaw and her head. Atlanta neurosurgeon Dr. Paul King met Morganu on a medical ...

Press Release: Market Review on Molecular Insight Pharmaceuticals,...  -  May 16, 2008
Pay-Per-View - M2 Presswire - HighBeam ResearchAbstract Title: "A phase I study of Iobenguane I 131 to evaluate MTD, efficacy and safety in patients with malignant pheochromocytoma/paraganglioma (Pheo)" ...

Article: All patients can choose QE.(News) - The Birmingham Post ( …  -  Jun 2, 2006
Pay-Per-View - Birmingham Post - HighBeam ResearchMann and colleagues, Queen Elizabeth Hospital (see also Paraganglioma . ... Pancreas, Paraganglioma, Queen Elizabeth Hospital. This article ... ...

The big 'C' getting bigger  -  Jun 1, 2009
Trinidad & Tobago ExpressIt was not Hodgkin's Lymphoma, but malignant paraganglioma. She paid $53000 to a nursing home to remove the mass. Now another one is growing in her stomach. ...

Peripartum Hypertension from Pheochromocytoma: A Rare and …  -  Oct 1, 2005
Nature.comA diagnostic work-up revealed a catecholamine-secreting paraganglioma in the retroperitoneum. The patient underwent a laparosopic resection of the tumor; ...

Pheochromocytoma Treatment - General Information  -  Dec 14, 2009
WebMDExtra-adrenal pheochromocytoma or functional paraganglioma occurs in approximately 10% to 15% of cases and may arise from any extra-adrenal chromaffin ...

Extraordinary life ends after 4-year battle with cancer  -  Aug 27, 2009
Minneapolis Star-Tribune - Minneapolis Star TribuneFour years ago after she was diagnosed with paraganglioma, Hunt Mortenson started a Caringbridge website on which she frequently wrote on everything from ...

Music in the Operating Room - New York Times  -  Apr 3, 2007
New York Times...“Paraganglioma maybe?? He sent it to the lab, along with a blood sample to see if the parathyroid hormone levels had started to come down, ...

Cancer claims crime boss before drug trial  -  Jan 24, 2007
Sydney Morning HeraldTHE organised crime boss Michael Hurley died yesterday of the rare cancer metastatic paraganglioma in Prince of Wales Hospital. He was 61. ...

Trial opens for Richfield man charged in killing; Jurors saw crime...  -  Jan 8, 2009
Pay-Per-View - Star Tribune - HighBeam ResearchHARLOW; STAFF WRITER Kathryn Rae (Kate) Hunt Mortenson was a wife and the mother of ... she was diagnosed with paraganglioma, Hunt Mortenson started a ...

Cancer cannot spare crime boss from jail: judge  -  Apr 13, 2006
Sydney Morning HeraldThe court had heard that Hurley has an extremely rare cancer, metastatic paraganglioma, which means that he is unlikely to survive more than three years. ...

Extraordinary life ends after 4-year battle with cancer; Kathryn Rae...  -  Aug 26, 2009
Pay-Per-View - Star Tribune - HighBeam ResearchFour years ago after she was diagnosed with paraganglioma, Hunt Mortenson started a Caringbridge website on which she frequently wrote on everything from ...

Cryoablation Provides Effect Palliation for Bone Metastasis  -  Apr 6, 2005
UroToday International JournalPrimary lesions included renal cell, bronchogenic, squamous cell, adrenal cortical, ovarian and thyroid carcinomas, paraganglioma, and desmoid tumors. ...

Cancer fighter Julian's running battle  -  Sep 20, 2008
WalesOnline...to take up the challenge on October 19 to raise money for Macmillan Cancer Support after discovering he had a malignant paraganglioma three months ago. ...

Frequent loss of 17p, but no p53 mutations or protein overexpression...  -  Jan 25, 2008
Nature.com...such as multiple endocrine neoplasia 2, Von Hippel–Lindau disease, neurofibromatosis type 1, and pheochromocytoma-paraganglioma syndrome. ...

An assessment of biochemical tests for the diagnosis of …  -  May 23, 2007
Nature.comHereditary disease had been diagnosed in 16 of the patients with pheochromocytoma (24%) and there were 14 patients with paraganglioma. ...

Should 123 I-MIBG scintigraphy be part of the workup for …  -  Sep 22, 2008
Nature.com...for pheochromocytoma, a past history of pheochromocytoma, or a family history of extra-adrenal pheochromocytoma (also referred to as paraganglioma). ...

Article: ALMANAC; Hunt of a Lifetime gets local boost.(SPORTS) - Star...  -  Jan 27, 2008
Pay-Per-View - Star Tribune - HighBeam ResearchHARLOW; STAFF WRITER Kathryn Rae (Kate) Hunt Mortenson was a wife and the mother of ... she was diagnosed with paraganglioma, Hunt Mortenson started a ...

THE crawl; NEWS AND NOTES FROM THE SCENE AND WWW.VITA.MN. …  -  Sep 18, 2008
Pay-Per-View - Star Tribune - HighBeam ResearchHARLOW; STAFF WRITER Kathryn Rae (Kate) Hunt Mortenson was a wife and the mother of ... she was diagnosed with paraganglioma, Hunt Mortenson started a ...

small business; Attorney, adviser, secret-keeper; Estate planning...  -  Nov 19, 2007
Pay-Per-View - Star Tribune - HighBeam ResearchHARLOW; STAFF WRITER Kathryn Rae (Kate) Hunt Mortenson was a wife and the mother of ... she was diagnosed with paraganglioma, Hunt Mortenson started a ...

Credit to Mom, mentors - Strong guidance kept Blakeley Cooper from …  -  May 14, 2007
$2.95 - Philadelphia Inquirer - NewsBankIn 2001, he was diagnosed with a rare form of cancer called paraganglioma. "You can never lose hope," he says. "I always remind myself, no matter how bad ...

Bicyclist's tumor rarest of the rare: He survives stroke, heart...  -  Jun 10, 2007
Free with registration - Akron Beacon Journal - AccessMyLibrary.comTumors in the heart are rare to begin with, but this one -- known as cardiac paraganglioma, or pheochromocytoma -- is among the rarest of the rare. ...

CANCER PATIENT DRAWS SUPPORT  -  Jul 26, 2005
Pay-Per-View - Modesto Bee - Factiva, from Dow JonesThe tumor is a rare form of cancer called metastatic paraganglioma. The thrill -- the joy -- of becoming a first-time father has been tempered by the fear, ...

Kelly William Maiden  -  Jul 21, 2006
$3.50 - The Sun - NewsBankHe was diagnosed with a very rare, incurable cancer, Paraganglioma, in September of 2004. After a valiant fight, he passed away at home on January 19, ...

Un estudio en hongos desvela un gen asociado a un cáncer humano  -  Jul 24, 2009
ADN.esTambién descubrieron que un grupo de pacientes humanos con paraganglioma hereditario, un raro tumor neuroendocrino, portaban mutaciones que inactivaban los ...

Bicyclist's tumor rarest of the rare: He survives stroke, heart...  -  Jun 10, 2007
Pay-Per-View - Akron Beacon Journal - HighBeam ResearchTumors in the heart are rare to begin with, but this one -- known as cardiac paraganglioma, or pheochromocytoma -- is among the rarest of the rare. ...

A patient with a juxtaglomerular cell tumor with histological...  -  Apr 7, 2008
Nature.com...(2007) The diagnosis and management of malignant phaeochromocytoma and paraganglioma. Endocr Relat Cancer 14: 569–585 | Article | PubMed | ChemPort | ...

Scientists discover gene mutation responsible for hereditary …  -  Jul 24, 2009
Science Centric...and their colleagues have identified the gene that is mutated in a hereditary form of a rare neuroendocrine tumour called paraganglioma (PGL). ...

Embryogenesis; Mitochondrial SDHD gene required for early …  -  Mar 7, 2005
Pay-Per-View - Stem Cell Week - Factiva, from Dow Jones...has recently been proposed to be involved in oxygen sensing because mutations that cause loss of its function produce hereditary familiar paraganglioma, ...

CAMPAIGN SPECIAL: Help us build beacon of hope  -  Apr 18, 2007
Glasgow Evening TimesKaren, who spent the final 11 weeks of her life in the hospice, died last July after suffering for five years from metastatic paraganglioma, a rare cancer ...

Molecular Insight Pharmaceuticals, Inc. Initiates Azedra(TM) Therapeut...  -  May 10, 2007
Genetic Engineering News - Genetic Engineering News (press release)..."There is an important need for new treatment options for pheochromocytoma and paraganglioma patients with malignant disease," said Dr. Edward Coleman, ...

TransMolecular Presents New Data Highlighting the Anti-angiogenic and...  -  Jun 1, 2009
Genetic Engineering News - Genetic Engineering News (press release)1/4 breast cancer patients, and one evaluable patient each with transitional cell carcinoma, pleomorphic xanthoastrocytoma and metastatic paraganglioma. ...

Welcome end to my pity party  -  Jun 11, 2008
phillyBurbs.comSomething called a paraganglioma, a word I believe knocked one kid out of this year's National Spelling Bee. Why did the inflexible drain tube near my ...

Novel Strategy for a Cocktail 18F-Fluoride and 18F-FDG PET/CT Scan...  -  Mar 16, 2009
Journal of Nuclear Medicine (subscriptio...3 prostate cancer, 2 breast cancer, 1 colon cancer, 1 lung cancer, and 1 malignant paraganglioma) who underwent separate 18 F PET/CT and 18 F-FDG PET/CT ...

Pheochromocytoma imaging with an unremarkable biochemical …  -  Dec 25, 2008
HemOncTodayPheochromocytoma and paraganglioma: comparison of MR imaging with CT and I-131 MIBG scintagraphy. Radiology . 1987;165:89-93. Sawka A, et al. ...

An unusually large choanal polyp that almost completely obstructed...  -  Aug 1, 2006
Free with registration - Ear, Nose and Throat Journal - AccessMyLibrary.com...paraganglioma, and nasopharyngeal extension of a parapharyngeal parotid tumor and (2) malignant disease such as carcinoma, lymphoma, and sarcoma. (3-5) ...

'WAY helped us cope with bereavement'  -  Jul 3, 2009
Oxford MailHis wife Michele was 42 when she died of paraganglioma — a rare form of lung disease which strikes 12 people worldwide every year, and kills eight of them. ...

Scientists discover gene mutation responsible for hereditary …  -  Apr 12, 2009
innovations report...and their colleagues have identified the gene that is mutated in a hereditary form of a rare neuroendocrine tumor called paraganglioma (PGL). ...

Pax-5 Gene Specific to B-Cell, Hodgkin's Lymphoma  -  Oct 23, 2006
MedscapeThey also studied benign and premalignant tumors, including carcinoid and paraganglioma. Pax-5 was absent in all of the normal specimens except lymphocytes ...

Donations to help pay bills asked  -  Oct 22, 2008
Cherokeean Herald - The Cherokeean HeraldMr. Ward has a paraganglioma tumor attached to the carotic artery in his neck. Three doctors will perform his surgery at the Houston hospital to remove the ...

Clinically guided genetic screening in a large cohort of Italian...  -  Feb 6, 2009
Journal of Clinical Endocrinology and...Conclusions: The frequency of the hereditary forms of pheochromocytoma/paraganglioma varies depending on the family history and the clinical presentation. ...



Background information on Paraganglioma [When available]

A paraganglioma is a rare neoplasm that can be found in the head and neck region and other less common areas. They are usually considered benign and complete surgical removal results in cure. However, in about 3% of cases they are malignant and have the ability to metastasize. Paragangliomas are still sometimes called glomus tumors (not to be confused with glomus tumors of the skin) and chemodectomas, but paraganglioma is the currently accepted and preferred term.

Paragangliomas arise from the glomus cells, which are special chemoreceptors located along blood vessels that have a role in regulating blood pressure and blood flow. The main concentration of glomus cells are found are in the carotid body, located in the upper neck at the branching of the common carotid artery, and the aortic bodies, located near the aortic arch. The glomus cells are a part of the paraganglion system composed of the extra-adrenal paraganglia of the autonomic nervous system, derived from the embryonic neural crest. Thus, paragangliomas are a type of neuroendocrine tumor, and are closely related to pheochromocytomas. Although all paragangliomas contain neurosecretory granules, only about 1-3% have clinical evidence of oversecretion.

Paragangliomas are found predominantly in the abdomen (85%) and the thorax (12%), and only 3% are found in the head and neck region. Most occur as single tumors. When they occur in multiple sites they are usually found as a part of a heritable syndrome such as multiple endocrine neoplasia types II-A and II-B and Carney's complex.

Familial paragangliomas are found in 10-50% of cases, are often multiple and bilateral, and occur at an earlier age. The genes SDHD (previously known as PGL1), PGL2, and SDHC (previously PGL3) have been identified as the genes which can cause familial paragangliomas when mutated.

According to the World Health Organization classification of neuroendocrine tumors, paragangliomas are classified as having a neural cell line of origin. In the categorization proposed by Wick, the paragangliomas belong to Group II

Search the web for more resources on Paraganglioma



Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy