Soft Tissue Sarcoma

This page contains recent news articles, when available, and an overview of Soft Tissue Sarcoma but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

News: Soft Tissue Sarcoma

On being thankful ...  -  ‎Nov 21, 2009‎
The Herald-MailAs a cancer, LMS is classified a malignant soft-tissue sarcoma, a harmful tumor that develops in body tissues such as fat, muscle, nerves and blood vessels. ...

Threshold Pharmaceuticals Presents Interim Data From a Phase 1/2 Clinical ...  -  ‎Nov 6, 2009‎ (press release)...which is investigating TH-302 in combination with doxorubicin in patients with soft tissue sarcoma who have not received prior doxorubicin. ...

'Doxo' Going to Like This One: Ziopharm's Phase II Wins Big  -  ‎Nov 6, 2009‎
BioWorld OnlineThe happy gist of Ziopharm Oncology Inc.'s interim Phase II news with palifosfamide for soft-tissue sarcoma came as little surprise, ...

Ziopharm Shows Positive Results (NASDAQ:ZIOP)  -  ‎Nov 9, 2009‎
FavStocks (blog)The randomized Phase 2 trial treats patients with unresectable or metastatic soft tissue sarcoma in the front- and second-line setting. ...

ArQule Announces Third Quarter Fiscal 2009 Results  -  ‎Nov 5, 2009‎
Reuters..."We recently received notification that the EMEA has designated ARQ 197 as an orphan medical product for the treatment of soft tissue sarcoma," said Mr. ...

Threshold Pharmaceuticals Presents Interim Prostate Cancer Data From Early ...  -  ‎Nov 18, 2009‎ (press release)The 403 trial is a Phase 1/2 clinical trial of TH-302 in combination with doxorubicin in patients with advanced soft tissue sarcoma. ...

ZIOPHARM Reports Third Quarter Financial Results and Updated Clinical Progress  -  ‎Nov 11, 2009‎
Business Wire (press release)The palifosfamide (Zymafos TM , ZIO-201) randomized Phase II trial in metastatic or unresectable soft tissue sarcoma achieved the study-specified efficacy ...

Benefits application simplified for Vietnam veterans  -  ‎Nov 9, 2009‎
Stanly News & PressNon-Hodgkin's Lymphoma, Porphyria Cutanea Tarda, Prostate Cancer, Respiratory Cancers and Soft Tissue Sarcoma (other than Osteosarcoma, Chondrosarcoma, ...

Non-invasive cancer treatment deemed a success  -  ‎Oct 28, 2009‎
XinhuaAfter that, bone tumors, breast tumors, liver cancer, soft tissue sarcoma, pancreatic cancer and various solid malignancies have been treated, ...

Threshold Pharmaceuticals Announces Clinical Development Results for Cancer ...  -  ‎Nov 12, 2009‎ (press release)...has been presented at various oncology conferences focused on the treatment of lung cancer, melanoma, soft tissue sarcoma, and solid tumors in general. ... www.Xtremepicks.Com: Xtremepicks Alerts November 6, 2009 ...  -  ‎Nov 6, 2009‎
Trading Markets (press release)...the multicenter randomized Phase II trial of palifosfamide (Zymafos(TM), ZIO-201) treating patients with unresectable or metastatic soft tissue sarcoma. ...

Jordan Paganelli : An Angel Gets His Wings  -  ‎Nov 11, 2009‎
Bay NetRhabdomyosarcoma - Alveolar subtype is a very aggressive, highly malignant soft-tissue Sarcoma which arises in undifferentiated muscle cells anywhere in the ...

Closing Bell: Unemployment must not be relevant (GE, ACOM, FNM, ZIOP, MOT, NVDA)  -  ‎Nov 6, 2009‎
BloggingStocks (blog)Meeting showing positive interim data for the Phase II trial of palifosfamide treating patients with unresectable or metastatic soft tissue sarcoma. ...

Morning Movers 11/06: ACLS, CVM, ZIOP, LPSN, CABL, ZGEN Higher; NHWK, GOK ...  -  ‎Nov 6, 2009‎ (subscription)...the multicenter randomized Phase II trial of palifosfamide (ZymafosTM, ZIO-201) treating patients with unresectable or metastatic soft tissue sarcoma. ...

Biovitrum Will Pay up to $533M for Swedish Orphan  -  ‎Nov 10, 2009‎
BioWorld OnlineYondelis (trabectidin), for which Swedish Orphan has marketing rights in the Nordic region and in eastern Europe, is approved in soft tissue sarcoma and in ...

Search in our News Channels  -  ‎Nov 18, 2009‎ (press release)...a randomized controlled Phase 2 trial in cancer of unknown primary (CUP), and studies in ovarian, colorectal and soft tissue sarcoma patients. ...

Biovitrum Creates Rare-Disease Focused Spec Pharma with Swedish Orphan Buy  -  ‎Nov 6, 2009‎
The IN VIVO Blog (blog)...anemia (Nascobal) and from cancer drug Yondelis, approved as second-line treatment for soft-tissue sarcoma and in-licensed from PharmaMar in 2007. ...

Infinity Reports Recent R&D Highlights and Third Quarter 2009 Results  -  ‎Nov 9, 2009‎ (press release) early 2010 a Phase 2 clinical study evaluating IPI-504 in patients with advanced, dedifferentiated liposarcoma, a form of soft tissue sarcoma. ...

Clinic Roundup  -  ‎Nov 6, 2009‎
Therapeutics Daily (press release) (registration)Threshold Pharmaceuticals Inc., of Redwood City, Calif., presented results of TH-302 in combination with doxorubicin in patients with soft-tissue sarcoma ...

Zeltia revenues up 15% boosted by Yondelis  -  ‎Oct 30, 2009‎
Pharma TimesThe figures reflect a rise in revenues from Yondelis (trabectedin) which is approved for the treatment of advanced soft tissue sarcoma in the European Union ...

EU Approves Zeltia's Yondelis For Ovarian Cancer  -  ‎Nov 2, 2009‎
Wall Street JournalYondelis, a drug derived from marine compounds, was approved for the treatment of soft-tissue sarcoma in the EU in 2007.

New Hampshire researchers propose new strategy for treating ...  -  07 Aug 2009
Mesothelioma News...pancreatic and biliary tract cancer, melanoma, glioblastoma, osteosarcoma, soft-tissue sarcoma, T-cell acute lymphoblastic leukemia and mesothelioma,

Patterns of Failure and Causes of Death Among Patients with Low ...  -  ‎Jul 16, 2009‎
American Journal of Hemotology and OncologyHowever, approximately 10% of patients with low-grade soft tissue sarcoma will die of their disease, and little is known about the patterns of failure and

Navigation-assisted bone tumor surgery may lead to better ...  -  ‎Aug 3, 2009‎
Ortho SuperSiteCho replied, “But, in the soft tissue sarcoma, we cannot technically attach the dynamic reference base.� Another audience member asked if the investigators

Why preserve a life with no meaning?  -  ‎Aug 4, 2009‎
Times OnlineThis time there was no missing the huge soft-tissue sarcoma that had strangled a kidney and attached itself to her aorta. The seven-hour operation was

'If you met Lauren, you will remember her'  -  ‎Aug 6, 2009‎
The CornishmanThe former Penair School pupil and Truro College student was taken ill with a rare and aggressive soft-tissue sarcoma in June 2007. Her mother said: "Anyone

Animal Cancer Center Looks at New Way to Treat Cancer, Enrolls Pet ...  -  ‎Jul 30, 2009‎
Colorado State University (press release) (press release)The soft tissue sarcoma study pays $500 toward the cost of treatment, such as surgery, at the end of the study. The study consists of six treatments over a

Ziopharm Oncology: Deal or Dilution?  -  ‎Aug 4, 2009‎
Seeking AlphaCurrently Ziopharm is running a randomized phase II trial targeting soft-tissue sarcoma (PICASSO) for this drug in the United States, Italy and Romania.

BUYINS.NET: IFC, TELK, CRXX, ARBX, FACE, ZIOP Expected To Be Lower ...  -  ‎Aug 3, 2009‎
Trading Markets (press release)...which is in phase II randomized controlled trial for the treatment of metastatic or unresectable soft tissue sarcoma as front- or second-line therapy.

CORRECT:UPDATE: Zeltia -35% After FDA Panel Rejects Yondelis  -  ‎Jul 16, 2009‎
Wall Street JournalYondelis, one of Zeltia's most important drugs, is currently used in Europe for treatment of soft-tissue sarcoma. At the end of last year,

Oklahoma cancer survivors to receive scholarships  -  ‎Aug 1, 2009‎
NewsOK.comColtrain was diagnosed with soft tissue sarcoma before he'd turned 2. His cancer spread so quickly that doctors had to amputate his right foot.

Methods comparison for high-resolution transcriptional analysis of ...  -  ‎Jul 20, 2009‎
BioTechniques.comSections of soft tissue sarcoma (STS) (including six leiomyosarcomas, three liposarcomas, three synovial sarcomas, and one unspecified pleomorphic spindle

R. Daniel Beauchamp, MD, FACS, Joins the Ranks of Leading ...  -  ‎Aug 3, 2009‎ (press release)...including gastrointestinal tract cancers including esophageal and colorectal cancers, breast cancer, melanoma and soft tissue sarcoma.

Member Of US Paralympic Curling Team Speaks To Students In Hartford  -  ‎Jul 16, 2009‎
Hartford CourantBut Perez's life changed drastically when, in 2000, he was diagnosed with soft tissue sarcoma, a rare form of cancer that affects fewer than 10000 people in

'Nam Vets Again Press VA on Agent Orange  -  ‎Jul 30, 2009‎
Military.comThe list also includes more than 30 types of soft tissue sarcoma, or tumors, as well as Type II diabetes and other illnesses. Rowan said the previous VA

Agent Orange still posing toxic threats  -  ‎Jul 25, 2009‎
Food ConsumerCancers found associated with Agent Orange include soft tissue sarcoma,Non-Hodgkin lymphoma, Hodgkin disease and chronic lymphocytic leukemia.

Melorheostosis: Clinicopathological Features, Diagnosis, and ...  -  ‎Jul 13, 2009‎
Ortho SuperSite...on radiographs and bone scintigraphy and, if not recognized as a manifestation of this disease, may be confused with a more ominous soft tissue sarcoma.

Soothing spa space helps a woman through illness  -  ‎Jul 21, 2009‎
OregonLive.comAnd it's where Hoffmann had successfully battled the soft-tissue sarcoma that attacked her abdominal muscles 12 years ago. Standing in her kitchen,

Photochemical technology demonstrates clinical potential for ...  -  ‎Jul 15, 2009‎
BioOptics World: Biotechnology and Biomedical NewsPhotochemistry and Photobiology, is the first to trial the PCI process on an aggressive tumor resembling that of human soft tissue sarcoma (STS).

National Cancer Institute Research Identifies Unique Mechanism of ...  -  ‎Jul 21, 2009‎
PR Newswire (press release)A phase II study of brostallicin in relapsed/refractory soft tissue sarcoma met its pre-defined activity and safety hurdles and resulted in a first-line

A Fish in the bucket is worth 146 in the sea  -  ‎Jul 13, 2009‎
Maui NewsLilio was diagnosed with a rare form of soft tissue sarcoma in October 2007. He had been a police officer for four years including a stint on patrol in

Babies of older mums have higher cancer risk  -  ‎Jul 15, 2009‎
HinduThey include leukaemia, lymphoma, central nervous system tumour, neuroblastoma, Wilms' tumour, bone cancer and soft tissue sarcoma.

BUYINS.NET: IFC, TELK, CRXX, ARBX, FACE, ZIOP Expected To Be Lower ...  -  ‎Aug 3, 2009‎
TMCnet...which is in phase II randomized controlled trial for the treatment of metastatic or unresectable soft tissue sarcoma as front- or second-line therapy.

New strategy in tumour treatment  -  ‎Jul 20, 2009‎
Science Centric...pancreatic and biliary tract cancer, melanoma, glioblastoma, osteosarcoma, soft-tissue sarcoma, mesothelioma, and T-cell acute lymphoblastic leukaemia.

Cancer patient hears Holocaust survivor's story  -  ‎Jul 16, 2009‎
KHOUHe's fighting soft tissue sarcoma at Medical City Children's Hospital, and as he endures his final chemotherapy treatment, he's getting the real-life

Shores family grateful for community support  -  Dec 2, 2008
Arizona Republic,The family learned that Spencer is only the ninth pediatric case of Ewing's soft tissue sarcoma in the eye orbit since 1958. He is expected to be done with

Oncolytics Biotech Inc.'s REOLYSIN(R) Exceeds Primary Statistical ...  -  Dec 11, 2008
Canada NewsWire (press release),Eligible patients must have a bone or soft tissue sarcoma metastatic to the lung deemed by their physician to be unresponsive to or untreatable by standard

Core Needle Biopsies of Musculoskeletal Tumors: Potential Pitfalls  -  Dec 18, 2008
Ortho SuperSite,Core needle biopsy for diagnosis of extremity soft tissue sarcoma. Ann Surg Oncol . 1997; 4(5):425-431. Kissin MW, Fisher C, Carter RL, Horton LW,

Stockbridge mourns loss of Molly Slator  -  Dec 13, 2008
Utica Observer Dispatch,Medical Center in Syracuse and eventually the cancer was diagnosed as non-rhabdomyosarcoma soft tissue sarcoma, a cancer that arises in soft tissue.

PharmaMar Announces The Initiation Of Phase II Studies With Irvalec®  -  Dec 26, 2008
Medical News Today (press release),Yondelis® has received Authorization for Commercialization from the European Commission for treating advanced soft tissue sarcoma.

ZIOPHARM Presents Positive Darinaparsin Phase II Data at ASH Meeting  -  Dec 8, 2008 (Pressemitteilung),Intravenous (IV) palifosfamide is currently in a Phase II randomized trial to treat soft tissue sarcoma. An oral form of palifosfamide has been developed

Keryx Biopharmaceuticals, Inc. Reports Phase 1/2 Data on KRX-0401 ...  -  Dec 9, 2008
Stockhouse,KRX-0401 has shown single agent partial responses in renal cell and hepatocellular carcinoma, soft tissue sarcoma, GIST tumors, mesothelioma, and carcinoma

PharmaMar Submits Registration Dossier To The EMEA For Yondelis(R ...  -  Dec 4, 2008
Medical News Today (press release),PharmaMar commercializes Yondelis® in the EU for the treatment of soft tissue sarcoma in adults, after failure of standard treatment.

Sunday, Dec. 14: Don't count out Cicero-North Syracuse despite ...  -  Dec 14, 2008
NY State Sportswriters Association,Molly Slator died yesterday from non-rhabdomyosarcoma soft tissue sarcoma, a rare childhood cancer. “The one big thing I’ve been telling people is,

TRAIL and Taurolidine induce apoptosis and decrease proliferation ...  -  Dec 12, 2008
7thSpace Interactive (press release),Disseminated soft tissue sarcoma still represents a therapeutic dilemma because effective cytostatics are missing. Therefore we tested TRAIL and Tarolidine

ZIOPHARM Presents Positive Darinaparsin Phase II Data At ASH Meeting  -  Dec 10, 2008
Medical News Today (press release),Intravenous (IV) palifosfamide is currently in a Phase II randomized trial to treat soft tissue sarcoma. An oral form of palifosfamide has been developed

Belinostat in its first pivotal trial in PTCL  -  Dec 17, 2008 (press release),B-cell lymphomas, AML, mesothelioma, soft tissue sarcoma, Myelodysplastic Syndrome (MDS), and liver, colorectal, and ovarian cancers, either alone or in

Background information on Soft Tissue Sarcoma [When available]

Malignant (cancerous) tumors that develop in soft tissue are called sarcomas, a term that comes from a Greek word meaning "fleshy growth."

In this context, the term soft tissue refers to tissues that connect, support, or surround other structures and organs of the body. Soft tissue includes muscles, tendons (bands of fiber that connect muscles to bones), fibrous tissues, fat, blood vessels, nerves, and synovial tissues (tissues around joints).

There are many different kinds of soft tissue sarcomas. They are grouped together because they share certain microscopic characteristics, produce similar symptoms, and are generally treated in similar ways. (Bone tumors, also known as osteosarcomas, are also called sarcomas, but are in a separate category because they have different clinical and microscopic characteristics and are treated differently.)

Sarcomas can invade surrounding tissue and can metastasize (spread) to other organs of the body, forming secondary tumors. The cells of secondary tumors are similar to those of the primary (original) cancer. Secondary tumors are referred to as "metastatic soft tissue sarcoma" because they are part of the same cancer and are not a new disease.

Some tumors of the soft tissue are benign (noncancerous). These tumors do not spread and are rarely life-threatening. However, benign tumors can crowd nearby organs and cause symptoms or interfere with normal body functions.

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