Abilify

This page contains recent news articles, when available, and an overview of Abilify but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Abilify
(when available)

Pharmacology and use:
Aripiprazole is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Aripiprazole is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), dopamine Type 2 (D2), 1 and 2 adrenergic, and H1 histaminergic receptors. Aripiprazole acts as an antagonist at other receptors, but with lower potency. Antagonism at receptors other than dopamine and 5HT2 with similar receptor affinities may explain some of the other therapeutic and side effects of Aripiprazole. Aripiprazole's antagonism of histamine H1 receptors may explain the somnolence observed with this drug. Aripiprazole's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug. For the treatment of schizophrenia

Mechanism Of Action:
Aripiprazole exhibits high affinity for dopamine D2 and D3, serotonin 5-HT1A and 5- HT2A receptors, moderate affinity for dopamine D4, serotonin 5-HT2C and 5-HT7, alpha1-adrenergic and histamine H1 receptors and moderate affinity for the serotonin reuptake pump. Aripiprazole has no appreciable affinity for cholinergic muscarinic receptors. Aripiprazole functions as a partial agonist at the dopamine D2 and the serotonin 5-HT1A receptors, and as an antagonist at serotonin 5-HT2A receptor.

News Articles on Aripiprazole

Many antipsychotic users not getting needed tests  -  04 Jan 2010
These so-called "second-generation" antipsychotic drugs, which include olanzapine (Zyprexa), risperidone (Risperdal) and aripiprazole (Abilify), ... Reuters

Call Big Pharma a DTC conservative  -  04 Jan 2010
Big brands like Lipitor and Abilify got $100 million-plus spending, while smaller drugs didn't. For more on which drugmakers boosted spending--Pfizer's ... FiercePharma

"Naughty" Pharma Still Got Xmas Presents From FDA  -  04 Jan 2010
It's no secret that the atypical antipsychotics Reinstein and Mendez-Villamil prescribed, which include Seroquel, Zyprexa and Abilify, are used to "manage" ... Scoop.co.nz

Drugging Kids for Profit  -  ‎Jan 3, 2010‎
They go by snazzy names such as Zyprexa, Geodon, Abilify, and Seroquel. Later, regulators allowed doctors to prescribe them for treating bipolar disorder. ... Portfolio.com

Jail's inmate medication bill large  -  ‎Jan 3, 2010‎
Abilify, a medication used as an add-on treatment for depression, as well as for the treatment of schizophrenia and manic episodes. 2. ... Topeka Capital Journal

Pharma sought safe havens for DTC in '09  -  ‎Dec 31, 2009‎
Otsuka Pharmaceuticals, which co-markets depression med Abilify with Bristol-Myers Squibb, exemplified the blockbuster mindset. ... Medical Marketing and Media

Autism Rates Jump 57% as Awareness of Disease Grows  -  ‎Dec 18, 2009‎
Bristol-Myers Squibb Co., based in New York, received regulatory approval in November for its mood-stabilizing drug, Abilify, to treat irritability ... Bloomberg

Happy New Year?  -  ‎Dec 30, 2009‎
There's a new ad spot on CBS for Abilify. I gotta check it out. Alright, sorry, I'm back, for good, I swear. (It's just that the meds kinda get me a little ... Huffington Post (blog)

"Naughty" Pharma Still Got Christmas Presents From FDA in 2009  -  ‎Dec 31, 2009‎
It's no secret that the atypical antipsychotics Reinstein and Mendez-Villamil prescribed, which include Seroquel, Zyprexa and Abilify, are used to "manage" ... NewsBlaze

Bristol-Myers Cuts 2009 Outlook - Analyst Blog  -  ‎Dec 24, 2009‎
However, the $1 billion addition in cost cuts in 2012−2013, the extension of the Abilify agreement with Otsuka and the acquisition of Medarex are ... Benzinga

Feds investigating high prescribing Fla. docs  -  ‎Dec 17, 2009‎
The drugs that Mendez-Villamil, a psychiatrist, prescribed most commonly included Seroquel, Zyprexa and Abilify. Seroquel is the only drug that has street ... MiamiHerald.com

The Shadowy Science Of Sex Addiction  -  ‎Dec 22, 2009‎
...and 12-step programs, although antidepressants (drugs llike Paxil or Zoloft) and antipsychotics like (these include Abilify and Zyprexa) may help. ... Forbes

Atypical Antipsychotics Increase Cardiometabolic Risk in Children  -  ‎Dec 29, 2009‎
2 The SATIETY study monitored treatment with aripiprazole (Abilify), olanzapine (Zyprexa), quetiapine (Seroquel), or risperidone (Risperdal), selected and ... Psychiatric Times

Anti-smoking drugs in health basket  -  ‎Dec 23, 2009‎
Provigil and Targin for neurology; Byetta and Victoza for diabetes; Humira, Enbrel, Remicade and Amevive for dermatology; Abilify for psychiatry; ... Jerusalem Post

In autism, medication is only a partial answer  -  ‎Dec 13, 2009‎
Abilify, a powerful second-generation antipsychotic, was given approval by the Food and Drug Administration to treat the irritability seen in this disorder. ... Boston Globe

More meds in the state-subsidized basket  -  ‎Dec 23, 2009‎
The drug Abilify is to be made available for 3300 people with schizophrenia. Treatments are to be subsidized for 500 people with severe psoriasis (on more ... Ha'aretz

Futures point to firmer Wall St opening  -  ‎Dec 9, 2009‎
A US drug regulatory advisory panel said on Tuesday current labeling for pediatric uses of Bristol-Myers Squib Co's antipsychotic drug, Abilify, ... Washington Post

Bristol-Myers Sets Swap Offer Rate  -  ‎Dec 17, 2009‎
However, the $1 billion addition in cost cuts in 2012−2013, the extension of the Abilify agreement with Otsuka and the acquisition of Medarex are ... Zacks.com

Why Are We Drugging Our Kids?  -  ‎Dec 14, 2009‎
...and include Seroquel by AstraZeneca; Risperdal and Invega marketed by Janssen, a division of J&J; Geodon by Pfizer; Abilify from Bristol-Myers Squibb; ... AlterNet

Psychiatric Meds Can Bring on Rapid Weight Gain in Kids  -  ‎Oct 27, 2009‎
Kids on Zyprexa gained the most, on average, while those taking Abilify gained the least. The 15 patients who had refused drug treatment gained less than ... U.S. News & World Report

Antipsychotic Drugs for Dementia To Be Curbed in UK  -  ‎Nov 12, 2009‎
...s Abilify and AstraZeneca Plc's Seroquel. The drugs, designed to treat schizophrenia, are often inappropriately used as a first-line therapy to quell ... Bloomberg

Bristol-Myers' Profit Rises, Tops Analyst Estimates  -  ‎Oct 22, 2009‎
...“Plavix and Abilify sales came in lower-than- expected.� Earnings in the quarter a year ago were boosted by the sale of wound products unit ConvaTec, ... Bloomberg

Bristol-Myers downsizes Abilify's sales force by 25%  -  ‎Oct 20, 2009‎
Although Bristol-Myers has downsized its Abilify's sales force, Otsuka made a commensurate increase in its Abilify sales force, thereby maintaining the ... Trading Markets (press release)

Generic Name: Aripiprazole, Arizol, Arlemide, Brisking, Ilimit, Irazem, Real One  -  ‎Nov 11, 2009‎
Abilify is the first medication approved by the FDA to help improve symptoms of depression in adults when added to an antidepressant. ... Pattaya Daily News

Antipsychotic Drugs Can Cause Rapid Weight Gain in Kids  -  ‎Nov 3, 2009‎
Abilify, a medication that is usually not linked with weight gain in adults, did cause the kids to gain weight but was not shown to raise blood sugar levels ... Fars News Agency

Children Gain Weight on Antipsychotic Medications  -  ‎Oct 31, 2009‎
Drugs/Medications included olanzapine (Zyprexa), quetiapine (Seroquel), risperidone (Risperadol) and aripiprazole (Abilify)—drugs sometimes used to treat ... Healia Health (blog)

Woman facing charges after traffic accident  -  ‎Nov 3, 2009‎
An officer said Davis gave police permission to search her purse and inside they found Abilify, Cymbalta, Estradiol and Detrol. She failed a field sobriety ... Port Clinton News Herald

Overmedicating our kids  -  ‎Nov 4, 2009‎
She is also going to family therapy sessions, where she is about to be put on the drug Abilify, a highly controversial drug, even for adults. ... Schenectady Gazette

B-MS posts strong sales for most of its drugs  -  ‎Oct 23, 2009‎
Bristol-Myers Squibb's third-quarter financials have revealed continued strong sales of the bloodthinner Plavix and the antipsychotic Abilify and the firm ... Pharma Times

Bristol-Myers Squibb Co. Q3 2009 Earnings Call Transcript  -  ‎Oct 22, 2009‎
So, not 100% of our efforts are devoted to this outstanding short-term performance but the ABILIFY contract extension, for example, where we changed the ... BNET

This Week in Health  -  ‎Oct 30, 2009‎
The drugs are Abilify, Risperdal, Seroquel and Zyprexa. The last two led to the largest weight gain. Neither has been approved for use in children. ... Intelihealth.com

Novartis rueful after Fanapt about-face  -  ‎Nov 9, 2009‎
N: Quote, Profile, Research) Abilify. Geodon generated sales of $1 billion in 2008. Sales of Zyprexa, by comparison, the biggest money-maker, ... Reuters India

Earnings for Two  -  ‎Oct 22, 2009‎
Results were driven by Plavix (up 8%) and Abilify (up 16%), Baraclude (up 33%), Sustiva (up 7%), Reyataz (up 5%), Orencia (up 36%) and Sprycell (up 30%). ... TheStreet.com (subscription)

The Antipsychotics Market Insight & Analysis By Bharatbook.com  -  ‎Nov 5, 2009‎
The antipsychotics market currently contains four blockbuster drugs; Zyprexa, Risperdal, Seroquel and Abilify. Visiongain predicts that a fifth drug will ... PRMinds (press release)

Is It Bipolar Disorder or Depression? Learn the Signs  -  ‎Nov 4, 2009‎
...antiseizure and mood stabilizing medications such as Depakote and Tegretol, as will as major tranquilizers such as Seroquel, Zyprexa and Abilify. ... FOXNews

Widespread Generic Erosion of Atypical Antipsychotics Will Cause the Bipolar ...  -  ‎Nov 5, 2009‎
...erosion of key antipsychotic agents such as AstraZeneca's Seroquel, Eli Lilly's Zyprexa, Bristol-Myers Squibb/Otsuka's Abilify and Pfizer's Geodon. ... Reuters

Bristol-Myers Squibb Achieves Strong Sales, Earnings Performance in Third Quarter  -  ‎Oct 22, 2009‎
Sales growth in the third quarter was led by continued sales increases for PLAVIX (+8%) and strong global sales growth for ABILIFY (+16%). ... Reuters

Bipolar drug market “to plummet from 2011â€?  -  ‎Nov 10, 2009‎
Bristol-Myers Squibb/Otsuka's Abilify (aripiprazole) and Pfizer's Geodon (ziprasidone), according to the study, from Decision Resources. ... Pharma Times

Forecast Insight - Depression - Generic induced brand erosion leads to market ...  -  ‎Oct 23, 2009‎
...upgraded its depression-specific Abilify and Seroquel forecasts following positive clinical trial data in depression for both atypical antipsychotics, ... PR-Inside.com (Pressemitteilung)

Merck, Novartis boost key drug sales  -  ‎Oct 22, 2009‎
Revenues grew by a respectable 4 percent to $5.49 billion, on growing sales of clotbuster Plavix and antipsychotic Abilify, which recently got a new ... FiercePharma

Use of antipsychotic medications in youth linked to increased weight ...  -  ‎Oct 28, 2009‎
Clinicians prescribed aripiprazole (Abilify, Otsuka) to 41 patients included in the analysis, olanzapine to 45 patients, quetiapine to 36 patients, ... Endocrine Today

US pharma looks to Japan as Japan eyes US  -  ‎Nov 5, 2009‎
The Bristol-Myers blockbuster antipsychotic Abilify, for example, was discovered by Japan's Otsuka Pharmaceutical; the two companies recently extended their ... FiercePharma

Texas Lawsuit Blames Antipsychotic Seroquel for Woman's Diabetes  -  ‎Oct 22, 2009‎
Risperdal, Zyprexa, and Abilify are brand names of other atypical antipsychotics. Many doctors prescribe Seroquel to treat post-traumatic stress disorder, ... Attorney at Law

Ahead of Earnings: AMZN, BMY, CMG, PM  -  ‎Oct 21, 2009‎
Plavix and Abilify both chalked up double-digit revenue gains and the company announced the acquisition of Medarex, a company that focuses on the ... Stock Traders Daily

Weekly Roundup  -  ‎Oct 23, 2009‎
2.63%) INDUSTRY SECTOR - HEALTHCARE: The earnings report was better than expected with solid reports from its key products Plavix and Abilify. ... TheStreet.com (subscription)

Internet News from an Inner Perspective  -  ‎Oct 22, 2009‎
The funny and sad thing is that I was just trying to think of some of those warnings above, and then the TV commercial for Abilify came on, and all I had to ... Salem-News.Com

New Report Just Published Blood-Brain Barrier: Bridging Options for Drug ...  -  ‎Oct 23, 2009‎
...for treatment of depression) and Bristol-Myers Squibb's/Otsuka's Abilify (aripiprazole, for treatment of bipolar disorder and schizophrenia). ... Live-PR.com (Pressemitteilung)

US stock market opening report (October 22, 2009, Thursday)  -  ‎Oct 22, 2009‎
Q3 Erbitux sales fell 3% to USD 179mln, Q3 Abilify sales rose 16% to USD 653mln, Exp. USD 686.3mln and Q3 Plavix sales rose 8% to USD 1.55bln, ... Stock Markets Review

Sicurezza e tollerabilità di Abilify  -  ‎Oct 20, 2009‎
Martedì 20 Ottobre 2009 - Si ritiene che l'efficacia dell'Aripiprazolo ( Abilify ) nel trattamento della schizofrenia sia mediata da una combinazione di ... XagenaSalute

Bristol-Myers Squibb corta 25% das equipas de vendas do Abilify®  -  ‎Oct 19, 2009‎
A Bristol-Myers Squibb (BMS) decidiu cortar na força de vendas do seu segundo fármaco mais vendido, o antipsicótico Abilify®, seis meses depois de ter ... RCM Pharma

BARN FÖRGIFTADE AV PSYKOFARMAKA – UPPSVÄLLDA KROPPAR, FÖRHÖJDA BLODFETTER OCH ...  -  ‎Nov 9, 2009‎
Det gjorde däremot de barn och ungdomar (4-19 år) som för första gången fick de nya antipsykosmedlen (Zyprexa, Risperdal, Abilify och Seroquel). ... MyNewsdesk (pressmeddelande)

Ð?ейролептики вызывают ожирение  -  ‎Oct 28, 2009‎
К нейролептикам, чаще вÑ?его вызывающим ожирение, отноÑ?Ñ?Ñ‚Ñ?Ñ? абилифай (Abilify), риÑ?пердал (Risperdal), Ñ?ероквель (Seroquel), зипрекÑ?а (Zyprexa). ... Вокруг Света

百时美施贵å®?第三季调整å?Žç›ˆåˆ©è¶…预期  -  ‎Oct 22, 2009‎
...该公å?¸è¡¨ç¤ºï¼Œå‡ æ¬¾å…³é”®è?¯ç‰©çš„销售é¢?实现了å?Œä½?数增长,包括精神分裂症和èº?éƒ?ç—‡è?¯ç‰©Abilifyã€?风湿性关节炎è?¯ç‰©Orenciaã€?白血病è?¯ç‰©Sprycel,以å?Šä¹™åž‹è‚?炎è?¯ç‰©Baraclude。 ... 东方财富网

百时美施贵å®?第三季调整å?Žç›ˆåˆ©è¶…预期  -  ‎Oct 26, 2009‎
...该公å?¸è¡¨ç¤ºï¼Œå‡ æ¬¾å…³é”®è?¯ç‰©çš„销售é¢?实现了å?Œä½?数增长,包括精神分裂症和èº?éƒ?ç—‡è?¯ç‰©Abilifyã€?风湿性关节炎è?¯ç‰©Orenciaã€?白血病è?¯ç‰©Sprycel,以å?Šä¹™åž‹è‚?炎è?¯ç‰©Baraclude。 ... 易富网

Les antipsychotiques causent un rapide et important gain de poids chez les jeunes  -  ‎Oct 27, 2009‎
Seuls deux de ces médicaments, l'Abilify et le Risperdal, n'ont obtenu d'autorisation de mise en marché (AMM) pour un usage pédiatrique et ce, ... PsychoMédia

'ìž?ì?´í”„렉사'등 정신약물 먹는 ì•„ì?´ 3달만ì—? 체중 8kg ↑  -  ‎Oct 27, 2009‎
BMSì?˜ ì—?빌리파ì?´(Abilify), 아스트ë?¼ì œë„¤ì¹´ì?˜ 세로퀠( Seroquel) 등ì?˜ 정신약물 복용ì?´ ì–´ë–¤ ì˜?í–¥ì?„ 주는지를 본 연구결과 ì?´ ê°™ì?´ 확ì?¸ë??다. ... 메디컬투데이

Pochi dati sulla sicurezza dei farmaci antipsicotici in gravidanza  -  ‎Oct 28, 2009‎
Risperidone ( Risperdal ), Olanzapina ( Zyprexa ), Quetiapina ( Seroquel ), Ziprasidone ( Gedeon ), Aripiprazolo ( Abilify ), Paliperidone ( Invega ). ... XagenaSalute

Lucros da Bristol-Myers Squibb um pouco acima das previsões  -  ‎Oct 23, 2009‎
As vendas do Abilify® cresceram 16%, para os 653 milhões de dólares, ficando acima das estimativas de 610 milhões de sete analistas da Thomson Reuters. ... RCM Pharma

Sindrome neurolettica maligna associata all'impiego degli antipsicotici atipici  -  ‎Oct 28, 2009‎
Aripiprazolo ( Abilify ), Ziprasidone ( Gedeon ), Amisulpiride ( Deniban ) e Quetiapina ( Seroquel ). Dall'analisi dei casi è emerso che, in generale, ... XagenaSalute

Bristol-Myers Squibb fait mieux que prévu au 3e trimestre  -  ‎Oct 22, 2009‎
Celles du médicament de lutte contre la schizophrénie Abilify ont progressé de 16%, à 653 millions de dollars, au-dessus des 610 millions envisagés par les ... nouvelobs.com

Légère hausse initiale à Wall Street  -  ‎Oct 22, 2009‎
...de dollars au troisième trimestre, dopé par la réduction de ses coûts et la hausse des ventes de médicaments phare comme le Plavix et l'Abilify. ... Investir.fr

Asocian antipsicóticos con aumento de peso en niños y jóvenes  -  ‎Oct 29, 2009‎
Algunos son: aripiprazol (Abilify), olanzapina (Zyprexa), quetiapina (Seroquel) y risperidona (Risperdal). Los efectos adversos de esos antipsicóticos ... Buena Salud

Les anti-psychotiques pour enfants créent des problèmes de poids  -  ‎Oct 28, 2009‎
Les patients ont été traités par de l'aripiprazole (Abilify), l'olanzapine (Zyprexa), la quétiapine (Seroquel), ou de la rispéridone (Risperdal) pendant 12 ... Le blog bébé (Blog)

Niños bajo fármacos psiquiátricos engordan  -  ‎Oct 28, 2009‎
Las medicinas empleadas fueron Abilify, Risperdal, Seroquel y Zyprexa. De las cuatro, Seroquel y Zyprexa aún no han sido aprobadas para usarlas con niños y ... El Informador

Estudio: Niç°½os bajo fç?ºrmacos psiquiç?ºtricos engordan  -  ‎Oct 27, 2009‎
Las medicinas empleadas fueron Abilify, Risperdal, Seroquel y Zyprexa. De las cuatro, Seroquel y Zyprexa aç¹³n no han sido aprobadas para usarlas con niç°½os ... Al Día (Texas)

Brand Names/Synonyms:
Abilify is also known by the following brand names and/or synonymsAbilify; Abilitat; Aripiprazole; Aripiprazole [Usan]; OPC 31

Drug Category:
Abilify is categorized under the following by the FDA: Antipsychotics; ATC:N05AX12

Dosage Forms:
Not Available

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one





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