Acamprosate Calcium

This page contains recent news articles, when available, and an overview of Acamprosate Calcium but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Acamprosate Calcium (when available)

Pharmacology and use:
Valdecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is classified as a nonsteroidal anti-inflammatory drug (NSAID). Valdecoxib is used for its anti-inflammatory, analgesic, and antipyretic activities in the management of osteoarthritis (OA) and for the treatment of dysmenorrhea or acute pain. Unlike celecoxib, Valdecoxib lacks a sulfonamide chain and does not require CYP450 enzymes for metabolism. For the treatment of osteoarthritis and dysmenorrhoea

Mechanism Of Action:
Both COX-1 and COX-2 catalyze the conversion of arachidonic acid to prostaglandin (PG) H2, the precursor of PGs and thromboxane. Valdecoxib selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, important for the mediation of inflammation and pain. Unlike non-selective NSAIDs, Valdecoxib does not inhibit platelet aggregation.

News Articles on Valdecoxib

BioWorld Today April 9, 2009  -  ‎Apr 8, 2009‎
A third candidate, a reformulated version of alcohol dependence drug acamprosate calcium, was in development for movement disorders. TMCnet

Ironwood Pharmaceuticals and Forest Laboratories Announce ...  -  May 21, 2008
Campral(R)* (acamprosate calcium), indicated in combination with psychosocial support for the maintenance of abstinence from alcohol in patients with FOXBusiness

Forest Laboratories, Inc. and Daiichi Sankyo, Inc. Announce the ...  -  May 12, 2008
Campral(R)** (acamprosate calcium), indicated in combination with psychosocial support for the maintenance of abstinence from alcohol in patients with Earthtimes (press release),

Forest Laboratories, Inc. (FRX) Study Demonstrates Lexapro(R ...  -  May 8, 2008
Campral(R)* (acamprosate calcium), indicated in combination with psychosocial support for the maintenance of abstinence from alcohol in patients with Lifescience-online,

Forest Laboratories, Inc. Reports Fiscal Year 2008 Fourth Quarter ...  -  Apr 15, 2008
Campral(R)* (acamprosate calcium), indicated in combination with psychosocial support for the maintenance of abstinence from alcohol in patients with PR Newswire (press release),

Forest Laboratories, Inc. Announces Amendment to Bystolic(TM ...  -  Feb 28, 2008
Campral(R)* (acamprosate calcium), indicated in combination with psychosocial support for the maintenance of abstinence from alcohol in patients with FOXBusiness

BUYINS.NET: REP, USS, ASMI, DCGN, SOMX, TSTC Have Been Removed ...  -  Feb 20, 2008
In addition, it is developing a new formulation of Acamprosate Calcium for the treatment of certain movement disorders. Somaxon Pharmaceuticals was founded Trading Markets (press release),

Brand Names/Synonyms:
Acamprosate Calcium is also known by the following brand names and/or synonyms:
Bextra; Valdecoxib; Valdecoxib [Usan]

Drug Category:
Acamprosate Calcium is categorized under the following by the FDA: Anti-inflammatory Agents; Nonsteroidal Antiinflammatory Agents (NSAIDs); ATC:M01AH03

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
4-(5-methyl-3-phenyl-oxazol-4-yl)benzenesulfonamide

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