Acamprosate Calcium

This page contains recent news articles, when available, and an overview of Acamprosate Calcium but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Acamprosate Calcium
(when available)

Pharmacology and use:
Valdecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is classified as a nonsteroidal anti-inflammatory drug (NSAID). Valdecoxib is used for its anti-inflammatory, analgesic, and antipyretic activities in the management of osteoarthritis (OA) and for the treatment of dysmenorrhea or acute pain. Unlike celecoxib, Valdecoxib lacks a sulfonamide chain and does not require CYP450 enzymes for metabolism. For the treatment of osteoarthritis and dysmenorrhoea

Mechanism Of Action:
Both COX-1 and COX-2 catalyze the conversion of arachidonic acid to prostaglandin (PG) H2, the precursor of PGs and thromboxane. Valdecoxib selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, important for the mediation of inflammation and pain. Unlike non-selective NSAIDs, Valdecoxib does not inhibit platelet aggregation.

News Articles on Valdecoxib

Brand Names/Synonyms:
Acamprosate Calcium is also known by the following brand names and/or synonymsBextra; Valdecoxib; Valdecoxib [Usan]

Drug Category:
Acamprosate Calcium is categorized under the following by the FDA: Anti-inflammatory Agents; Nonsteroidal Antiinflammatory Agents (NSAIDs); ATC:M01AH03

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
4-(5-methyl-3-phenyl-oxazol-4-yl)benzenesulfonamide





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