AccuNeb

This page contains recent news articles, when available, and an overview of AccuNeb but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

AccuNeb (when available)

Pharmacology and use:
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity. For relief and prevention of bronchospasm due to asthma; Emphysema; Chronic bronchitis

Mechanism Of Action:
Albuterol is a beta(2)-adrenergic agonist. It stimulates beta(2)-adrenergic receptors. Binding of albuterol to beta(2)-receptors in the lungs results in relaxation of bronchial smooth muscles. It is believed that Albuterol increases cAMP production by activating adenylate cyclase, and the actions of albuterol are mediated by cAMP. Increased intracellular cyclic AMP increases the activity of cAMP-dependent protein kinase A, which inhibits the phosphorylation of myosin and lowers intracellular calcium concentrations. A lowered intracellular calcium concentrations leads to a smooth muscle relaxation. Increased intracellular cyclic AMP concentrations also cause an inhibition of the release of mediators from mast cells in the airways.

News Articles on Albuterol

Brand Names/Synonyms:
AccuNeb is also known by the following brand names and/or synonymsAH 3365; Accuneb; Aerolin; Albuterol; Albuterol Sulfate; Albuterol Sulfate Hfa; Asmaven; Broncovaleas; Cetsim; Cobutolin; Ecovent; Loftan; Proventil; Proventil Inhaler; Proventil-Hfa; Rotahaler; Salbulin; Salbutamol; Salbutamol Free Base; Salbutamol Sulfate; Salbutamol Sulphate; Salbutard; Salbutine; Salbuvent; Solbutamol; Sultanol; Venetlin; Ventalin Inhaler; Ventolin; Ventolin Hfa; Ventolin Inhaler; Ventolin Rotacaps; Volma; Volmax; Xopenex; Xopenex Hfa

Drug Category:
AccuNeb is categorized under the following by the FDA: Adrenergic beta-Agonists; Tocolytic Agents; Bronchodilator Agents; ATC:R03AC

Dosage Forms:
ORAL SOLUTION; SYRUP; TABLETS; EXTENDED-RELEASE TABLETS; INJECTION (Intramuscular, Intravenous)

Absorption:
Systemic absorption is rapid following aerosol administration

Interactions:
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Chemical IUPAC Name:
2-(hydroxymethyl)-4-(1-hydroxy-2-tert-butylamino-ethyl)-phenol

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