AccuNeb

This page contains recent news articles, when available, and an overview of AccuNeb but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

AccuNeb (when available)

Pharmacology and use:
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity. For relief and prevention of bronchospasm due to asthma; Emphysema; Chronic bronchitis

Mechanism Of Action:
Albuterol is a beta(2)-adrenergic agonist. It stimulates beta(2)-adrenergic receptors. Binding of albuterol to beta(2)-receptors in the lungs results in relaxation of bronchial smooth muscles. It is believed that Albuterol increases cAMP production by activating adenylate cyclase, and the actions of albuterol are mediated by cAMP. Increased intracellular cyclic AMP increases the activity of cAMP-dependent protein kinase A, which inhibits the phosphorylation of myosin and lowers intracellular calcium concentrations. A lowered intracellular calcium concentrations leads to a smooth muscle relaxation. Increased intracellular cyclic AMP concentrations also cause an inhibition of the release of mediators from mast cells in the airways.

News Articles on Albuterol

US Patent and Trademark Office Issues Mylan's Specialty Division ...  -  Jan 12, 2009
The Web sites for Dey LP include www.dey.com, www.accuneb.com, www.curosurfusa.com, www.cyanokit.com, www.duoneb.com, www.epipen.com and PR Newswire (press release),

Nebulized Perforomist(TM) Inhalation Solution Provided Prolonged ...  -  Oct 29, 2008
The Web sites for Dey, LP include http://www.dey.com, http://www.accuneb.com, http://www.curosurfusa.com, http://www.cyanokit.com, http://www.duoneb.com, Trading Markets (press release),

$21M settlement ironed out for drug cost lawsuit  Sep 11, 2008
Drugs named in the list include AccuNeb, Cisplatin, Lidocaine hydrochloride, and Novacaine. The lawsuit accused 11 drug makers of unlawfully inflating theCNNMoney.com

Florida EMS and Fire Vehicles to Stock Cyanokit(R) 5g ...  -  May 29, 2008
The Web sites for Dey, LP include www.dey.com, www.accuneb.com, www.curosurfusa.com, www.cyanokit.com, www.duoneb.com, www.epipen.com and PR Newswire (press release),

Concomitant Treatment With Nebulized Formoterol Fumarate and ...  -  May 20, 2008
The Web sites for Dey, LP include www.dey.com, www.accuneb.com, www.curosurfusa.com, www.cyanokit.com, www.duoneb.com, www.epipen.com and PharmaLive.com (press release),

Clinical Trial Data for Perforomist(TM) Inhalation Solution to be ...  -  May 16, 2008
The Web sites for Dey, LP include www.dey.com, www.accuneb.com, www.curosurfusa.com, www.cyanokit.com, www.duoneb.com, www.epipen.com and Earthtimes (press release),

Concomitant use of Perforomist & tiotropium -- significant ...  -  May 20, 2008
The Web sites for Dey, LP include www.dey.com, www.accuneb.com, www.curosurfusa.com, www.cyanokit.com, www.duoneb.com, www.epipen.com and Genetic Engineering News (press release),

PARI Nebulizer & Compressor Used Exclusively in Inspire's Phase 3 ...  -  10 Mar 2008
...sales including AstraZeneca's Pulmicort Respules, Sepracor's Xopenex and Brovana, Novartis' TOBI, Genentech's Pulmozyme, and DEY LP's Accuneb, Duoneb, CNNMoney.com (press release)

Brand Names/Synonyms:
AccuNeb is also known by the following brand names and/or synonyms:
AH 3365; Accuneb; Aerolin; Albuterol; Albuterol Sulfate; Albuterol Sulfate Hfa; Asmaven; Broncovaleas; Cetsim; Cobutolin; Ecovent; Loftan; Proventil; Proventil Inhaler; Proventil-Hfa; Rotahaler; Salbulin; Salbutamol; Salbutamol Free Base; Salbutamol Sulfate; Salbutamol Sulphate; Salbutard; Salbutine; Salbuvent; Solbutamol; Sultanol; Venetlin; Ventalin Inhaler; Ventolin; Ventolin Hfa; Ventolin Inhaler; Ventolin Rotacaps; Volma; Volmax; Xopenex; Xopenex Hfa

Drug Category:
AccuNeb is categorized under the following by the FDA: Adrenergic beta-Agonists; Tocolytic Agents; Bronchodilator Agents; ATC:R03AC

Dosage Forms:
ORAL SOLUTION; SYRUP; TABLETS; EXTENDED-RELEASE TABLETS; INJECTION (Intramuscular, Intravenous)

Absorption:
Systemic absorption is rapid following aerosol administration

Interactions:
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Chemical IUPAC Name:
2-(hydroxymethyl)-4-(1-hydroxy-2-tert-butylamino-ethyl)-phenol

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