Acetazolamide

This page contains recent news articles, when available, and an overview of Acetazolamide but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Acetazolamide
(when available)

Pharmacology and use:
Acetazolamide is a potent carbonic anhydrase inhibitor, effective in the control of fluid secretion, in the treatment of certain convulsive disorders and in the promotion of diuresis in instances of abnormal fluid retention. Acetazolamide is not a mercurial diuretic. Rather, it is a nonbacteriostatic sulfonamide possessing a chemical structure and pharmacological activity distinctly different from the bacteriostatic sulfonamides. For adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies; chronic simple (open-angle) glaucoma

Mechanism Of Action:
The anticonvulsant activity of Acetazolamide may depend on a direct inhibition of carbonic anhydrase in the CNS, which decreases carbon dioxide tension in the pulmonary alveoli, thus increasing arterial oxygen tension. The diuretic effect depends on the inhibition of carbonic anhydrase, causing a reduction in the availability of hydrogen ions for active transport in the renal tubule lumen. This leads to alkaline urine and an increase in the excretion of bicarbonate, sodium, potassium, and water.

News Articles on Acetazolamide

The Festive Side of Carbon Dioxide  -  ‎Dec 17, 2009‎
Their discovery was inspired by reports of mountaineers who had lost their taste for bubbles after taking a medication called acetazolamide, which is used ... Wall Street Journal

Altitude sickness can hit some hard in Vail  -  ‎Dec 22, 2009‎
Well established as a preventative, acetazolamide (Diamox) is often used and is about 75 percent effective. Started one day in advance, and continued ... Vail Daily News

Episodic Vertigo Responds to Acetazolamide Therapy: Presented at ANA  -  ‎Oct 20, 2009‎
BALTIMORE, Md -- October 20, 2009 -- Acetazolamide is safe and effective in the treatment of patients with episodic vertigo, ... DG News

BC ARTHRITIS STRENGTH  -  ‎Nov 10, 2009‎
Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids ... Monthly Prescribing Reference

Fifty Years of Thiazide Diuretic Therapy for Hypertension  -  ‎Nov 9, 2009‎
Seven years later, the development of the carbonic anhydrase inhibitor acetazolamide helped us to understand the mechanism for urinary acidification and ... Archives of Internal Medicine

What Does Carbon Dioxide Taste Like? Fizzy Drinks Can Tell The Human Tongue  -  ‎Oct 19, 2009‎
The study also explains the the reason why people do not get the taste of champagne, beer and other fizzy drinks when on an acetazolamide, a prophylactic ... MedIndia

Extending a nurse practitioner's role to undertake advanced procedures  -  ‎Oct 19, 2009‎
After treatment, one 250mg tablet of acetazolamide was given (providing this was not contraindicated) and intraocular pressures were rechecked one hour ... Nursing Times

Tong heeft antenne voor 'bruis'  -  ‎Oct 21, 2009‎
Een van de twee ondertekenaars, de arts Stephen Kelleher, had zopas een berg beklommen en daarbij het medicijn acetazolamide geslikt, ter preventie van ... De Standaard

Medicina di montagna: il convegno di Viterbo  -  ‎Nov 1, 2009‎
L'acetazolamide a basse dosi pare migliorare la qualità del sonno stimolando i centri del respiro, ma l'acclimatazione rimane il miglior modo per ... DiscoveryAlps - Incontrarsi sulle Alpi

Brand Names/Synonyms:
Acetazolamide is also known by the following brand names and/or synonymsAcetamidothiadiazolesulfonamide; Acetamox; Acetazolam; Acetazolamid; Acetazolamide; Acetazolamide Sodium; Acetazolamine; Acetazoleamide; Acetozalamide; Ak-Zol; Apo-Acetazolamide; Atenezol; Carbonic Anhydrase Inhibitor; Carbonic Anhydrase Inhibitor 6063; Cidamex; Dazamide; Defiltran; Dehydratin; Diacarb; Diakarb; Diamox; Diamox Sequels; Didoc; Diluran; Diuramid; Diureticum-Holzinger; Diuriwas; Diutazol; Donmox; Duiramid; Edemox; Eumicton; Fonurit; Glaupax; Glupax; Natrionex; Nephramid; Nephramide; Phonurit; Sk-Acetazolamide; Storzolamide; Vetamox

Drug Category:
Acetazolamide is categorized under the following by the FDA: Diuretics; Anticonvulsants; Carbonic Anhydrase Inhibitors; ATC:S01EC01

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)ethanamide





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