Activin

This page contains recent news articles, when available, and an overview of Activin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Dynamic regulation of CD24 and the invasive, CD44posCD24neg phenotype in ...  -  ‎Nov 11, 2009‎
This interconversion was found to be dependent upon Activin/Nodal signaling. Methods: Breast cancer cell lines were sorted into CD44posCD24pos and ... 7thSpace Interactive (press release)

Acceleron Pharma Initiates First-in-Human Study of ACE-041, a Novel ...  -  ‎Nov 4, 2009‎
ACE-041 is a novel angiogenesis inhibitor that binds to and prevents members of the TGF-β superfamily from signaling through the activin receptor-like ... Reuters

Celgene Reports Record Third Quarter 2009 Operating and Financial Results  -  ‎Oct 22, 2009‎
...oral anti-inflammatory compounds; our kinase inhibitor programs; our Activin inhibitor program with ACE-011 and placenta-derived stem cell programs. ... Reuters

Celgene Reports Record Third Quarter 2009 Operating and Financial Results  -  ‎Oct 22, 2009‎
...oral anti-inflammatory compounds; our kinase inhibitor programs; our Activin inhibitor program with ACE-011 and placenta-derived stem cell programs. ... Business Wire (press release)

Trucuri si cosmetice care te intineresc  -  ‎Nov 4, 2009‎
Observand modul in care se vindeca o taietura cutanata, cercetatorii de la Institutul Avon au descoperit si molecula reparatoare: Activin. ... Avantaje

Researchers zero in on key cancer agent  -  ‎Aug 11, 2009‎
The research, which focuses on the role of a recently discovered growth regulator called activin C, has the potential to characterise the protein as a New Zealand Herald

Protein may hold key to prostate ills  -  ‎Aug 14, 2009‎
The promising research focuses on clarifying the role of a recently-discovered growth regulator called activin C. This protein is also a potential Otago Daily Times

Role of Follistatin in Promoting Adipogenesis in Women  -  ‎Aug 5, 2009‎
Context: Follistatin is a glycoprotein that binds and neutralizes biological activities of TGFβ superfamily members including activin and myostatin. Journal of Clinical Endocrinology and Metabolism

VitaCore Laboratories Introduces Euphallic: The Next-Generation ...  -  ‎Aug 6, 2009‎
ActiVin® - Increases nitric oxide production which increases the elasticity of the blood vessels in the penis. Damiana - Relaxing, warming aphrodisiac; Emediawire (press release)

Six nouveaux intronisés au temple de la renommée et une pétition ...  -  ‎Aug 26, 2009‎
Bernard Trottier, de Bernard Trottier Sports, et Robert Labelle, président de Importations Activin, ainsi qu'en présence de plusieurs personnalités que CNW Telbec (Communiqué de presse)

Activin A induces ovine follicle stimulating hormone beta using ...  -  ‎Jun 24, 2009‎
Activin A increases production of follicle stimulating hormone (FSH) by inducing transcription of its beta subunit (FSHB). This induction has been studied 7thSpace Interactive (press release)

Activin signaling as an emerging target for therapeutic interventions  -  ‎Jun 18, 2009‎
Activin receptors are shared by multiple transforming growth factor-beta (TGF-beta) ligands such as myostatin, growth and differentiation factor-11 and 7thSpace Interactive (press release)

Graceway Acquires Dermatological Compounds from Pfizer  -  ‎Jul 2, 2009‎
In addition, Graceway will acquire an activin-like kinase 5 (ALK-5) inhibitor, currently in early preclinical development for the reduction of surgical and Genetic Engineering News (press release)

Acceleron Pharma Presents Preclinical Study Results for ACE-041 at ...  -  ‎Apr 14, 2009‎
ACE-041 is a protein therapeutic that works by blocking signaling through Activin receptor-like kinase 1 (ALK1), a receptor in the Growth and Business Wire (press release)

Hereditary hemorrhagic telangiectasia  -  ‎Apr 13, 2009‎
Several mutations in 2 genes, endoglin on chromosome 9 (HHT type 1) and activin receptor-like kinase-1 on chromosome 12 (HHT type 2), are associated with CMAJ

山中伸弥Cell Stem Cell倡议建立干细胞新标  -  18 Mar 2009
...germ layers: classical ESCs, epiblast-derived stem cells (EpiSCs), and Fibroblast Growth Factor/Activin/Bio cultivated stem cells (FAB-SCs), among them. 生物通

Celgene (CELG): Strong growth in biotech  -  ‎Feb 23, 2009‎
Leverage clinical potential of Activin Biology by completing Celgene/Acceleron Phase II Study of ACE-011 in Multiple Myeloma Patients With Cancer-Related BloggingStocks

Celgene Reports Record Fourth Quarter and Full Year 2008 Product ...  -  Jan 29, 2009
...our oral anti-inflammatory compounds; as well as our kinase inhibitor programs; our Activin inhibitor program and placenta-derived stem cell programs. Trading Markets (press release),

Celgene Corp. Q4 2008 Earnings Call Transcript  -  Jan 29, 2009
This new biologic targets the activin receptor, and is designed to increase bone formation while decreasing bone resorption. The compound is currently being Seeking Alpha,

Changes in the reproductive function and developmental phenotypes ...  -  Dec 15, 2008
The TGF-beta family protein activin has numerous reported activities with some uncertainty in the reproductive axis and development. 7thSpace Interactive (press release),

Wellness Foods: Products to Watch in 2009  -  Dec 14, 2008
But it also adds DSM Nutritional Products’ (www.dsm.com) Teavigo green tea extract, San Joaquin Valley Concentrate’s (www.activin.com) Activin grape seed Food Processing,

ACE-011 Phase 1 Results Published in the Journal of Bone and ...  -  Dec 18, 2008
ACE-011, a soluble form of the activin receptor type IIA (ActRIIA), is a biologic therapeutic agent that inhibits signaling through the ActRIIA receptor, MarketWatch

StockPicking.com: Stock Trade Newsletter Reports about its Alert ...  -  Dec 5, 2008
ACE-011 is a novel biologic agent that binds tightly to activin and inhibits signaling through the activin type IIA receptor (ActRIIA). Trading Markets (press release),

Leveranciers topwijnen fuseren  -  Dec 1, 2008
...bedrijf gaat Lenselink de wijn aan de man brengen. Bert de Boer heeft ook nog belangen in wijnhandel Activin. Daarnaast bezit hij het Haagse wijncafé Taste. Misset Horeca,

Cripto Localizes Nodal at the Limiting Membrane of Early Endosomes  -  Nov 12, 2008
The EGF domain is thought to recruit Nodal, whereas the CFC domain mediates binding to activin receptor–like kinase 4 (ALK4). We found that the EGF-like Science Magazine (subscription)

Latest research on diagnosis and treatment of allergic diseases  -  Nov 11, 2008
..."Human Mast Cells Stimulate Bronchial Epithelial Cells to Produce Plasminogen Activator Inhibitor-1 Via TGF-Beta and Activin A." (Abstract #54: Nov. News-Medical.net,

Die wichtigste Nebensache der Ernährung  -  Nov 18, 2008
Zu diesen Radikalfängern gehören beispielsweise Lycopin aus Tomaten, Activin in Traubenkernen, Flavonoide wie Resveratol im Rotwein, Quercetin in Zwiebeln MedUNIQA Gesundheitsweb,

干细胞�?沿科学家邓�?�?简介（学术篇）  -  Nov 6, 2008
Inducing Embryonic Stem Cells to Differentiate into Pancreatic Beta Cells by a Novel Three-Step Approach with Activin 生物通,

Acceleron, Celgene begin Phase 2 multiple myeloma study  -  Oct 16, 2008
...initiated a Phase 2 clinical trial for patients with multiple myeloma using its drug ACE-011, an activin receptor type IIA that induces bone formation. Mass High Tech,

Firm Introduces Flavored Anti-malaria Drugs  -  Sep 26, 2008
Also in the Tyonex anti-malaria range is Activin, a combination of Artesunate and Amodiaquine tablets, designed to “flush out malaria fast,�? according to THISDAY,

Timely diagnosis, treatment of HHT can improve outcomes  -  Oct 1, 2008
Mutations in endoglin (ENG) on chromosome 9 and activin receptor-like kinase (Alk-1) on chromosome 12 are among the most common. AAP News (subscription)

Deregulation of Stat5 in the mammary gland of transgenic mice ...  -  Sep 23, 2008
This is supported by the higher expression of genes involved in O-glycan synthesis, TGF-beta, activin, their receptors and Smad3, as well as the Notch 7thSpace Interactive (press release),

人类胚胎干细胞命�?调控新�?�现  -  Oct 15, 2008
...研究�?�现，TGF-β信�?�超家�?(包括Activin 中国生物技术信�?�网,

推动干细胞科研�?�展加强与国际科学家的交�?  -  Oct 19, 2008
...康涅狄格大学�?�生中心的�?�?和教授分别作了题目为“由胚胎干细胞产生的胰岛细胞�?�?“人胚胎干细胞中TGFβ/Activin 北方网,

Lesions of the Adrenal Cortex  Aug 30, 2008
Vanttinen T, Liu J, Kuulasmaa T, Kivinen P, Voutilainen R. Expression of activin/inhibin signaling components in the human adrenal gland and the effects ofRedOrbit,

TGFβ induces SIK to negatively regulate type I receptor kinase ...  Aug 25, 2008
Abbreviations used in this paper: ALK, activin receptor-like kinase; BMP, bone morphogenetic protein; CA, constitutively active; GAPDH,Journal of Cell Biology (subscription)

[비만퇴치 실전 가�?�드]여성과 비만관리  Aug 21, 2008
...�?� 파�?� 빈�?��?� �?가와 �?�로 �?�한 LH-β 전사 RNA�?� 발현 �?가 �? 뇌하수체 내�?서 FSH와 고친화력�?� 가진 activin 결합단백질�?� follistatin�?� �?가를 유�?�한다.디지틀보사,

Aging Baby Boomers Devoting Nutrition and Money to Maintain Eye Health  -  06 Aug 2008
San Joaquin Valley Concentrates (www.activin.com), Fresno, Calif., offers ActiVin brand of oligomeric proanthocyanidin (OPC), a polyphenolic bioflavanoid Food Processing,

Mutation study of Spanish patients with Hereditary Hemorrhagic ...  -  Aug 1, 2008
...and age-dependent vascular disorder characterised mainly by mutations in the Endoglin (ENG) or activin receptor-like kinase-1 (ALK1, ACVRL1) genes. 7thSpace Interactive (press release),

What's New in Orthopaedic Research  -  Aug 1, 2008
Previously, the group of Edward Schwarz, PhD, at the University of Rochester reported on the use of AAV encoding a constitutively active form of activin Journal of Bone and Joint Surgery (subscription)

´다분화 능력 조절 유전�?´ 국내연구진�?� �?혀  -  Jul 8, 2008
...�?�스�?�?� 8�?� �?명과학과 한진관(50) �?수팀�?� ‘랩2(Rap2)’ �?�는 유전�?가 �?�간 배아줄기세�?��?� 다분화능력�?� 유지하는�?� 필요한 액티빈(Activin)과 노들(Nodal) �?��?�리안,

Endometrial Inhibin/Activin β-B Subunit Expression Is Related to ...  -  Jun 6, 2008
Results: Inhibin/activin β-B expression was lower in decidualized endometrium from ectopic pregnancies when compared with that of ongoing pregnancies (P Journal of Clinical Endocrinology and Metabolism,

Targeted Anticancer Drugs - In Vitro Assessment and Non-Invasive ...  -  Jun 11, 2008
TACE; acidic fibroblast growth factor (aFGF); activin receptor IIA (ActrIIA); adenosine deaminase; adenosine monophosphate (AMP); alpha5beta1 integrin; Earthtimes (press release),

Yasushi Saka: Stirring a melting pot of math and morphogens  -  02 Jun 2008
The morphogen, activin, which Saka studies, prompts a regulatory protein to enter the nucleus and activate target genes (right). My grandparents once lived Journal of Cell Biology (subscription)

Novel Mechanisms Controlling Insulin Release And Fat Deposition ...  -  May 13, 2008
In agreement with these results, mice lacking Activin B also developed hyperinsulinemia to a similar extent as ALK7 mutants. "In other words, our data Science Daily (press release)

The pregnancy-associated glycoprotein-hormones activin A and ...  -  May 6, 2008
...family including activin A (ActA) and inhibin A (InA) are candidates that could direct the differentiation of DCs into a tolerance-inducing phenotype. 7thSpace Interactive (press release),

ACE-011 Preclinical Data Published in the Proceedings of the ...  -  May 7, 2008
..."A Soluble Activin Type IIA Receptor Induces Bone Formation and Improves Skeletal Integrity" was published in the journal Proceedings of the National PR-Inside.com (Pressemitteilung),

Basal Expression of Bone Morphogenetic Protein Receptor Is Reduced ...  -  May 16, 2008
Smad1/5 (pSmad1/5) expression together with induction of activin-like kinase (ALK)-2 and ALK-6 mRNA and protein after inhaled allergen (20). RedOrbit,

Women Involved in Sexual Offences Have Mental Issues  -  May 16, 2008
The research is the largest study ever conducted of women convicted of sexual offences in Sweden. Between 1988 and 2000, 93 women and 8500 men were MedIndia,

Growing human eggs in the lab  -  Apr 21, 2008
Thirty-eight of the culture plates contained a chemical called activin, which has been shown to be important in growing and maturing eggs from sheep and NHS Choices,

Acceleron Pharma Announces Global Collaboration with Celgene ...  -  Feb 21, 2008
ACE-011, a protein therapeutic based on the activin receptor type IIA, is a novel bone-forming agent. In numerous pre-clinical models of bone loss, Lifescience-online,

Acceleron, Celgene in Potential $1.8B Bone Loss Collaboration  -  Feb 20, 2008
ACE-011, a protein drug designed to work by inhibiting activin, a negative regulator of bone mass, has demonstrated in preclinical studies an ability to BioWorld Online,

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