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AloxiThis page contains recent news articles, when available, and an overview of Aloxi but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Aloxi (when available) Palonosetron is an antinauseant and antiemetic agent indicated for the prevention of nausea and vomiting associated with moderately-emetogenic cancer chemotherapy and for the prevention of postoperative nausea and vomiting. Palonosetron is a highly specific and selective serotonin 5-HT3 receptor antagonist, not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors. For the treatment of aausea and vomiting associated with cancer chemotherapy Mechanism Of Action: Palonosetron is a selective serotonin 5-HT3 receptor antagonist. The serotonin 5-HT3 receptors are located on the nerve terminals of the vagus in the periphery and centrally in the chemoreceptor trigger zone of the area postrema. It is thought that chemotherapeutic agents produce nausea and vomiting by releasing serotonin from the enterochromaffin cells of the small intestine, and that the released serotonin then activates 5-HT3 receptors located on vagal efferents to initiate the vomiting reflex. Therefore Palonosetron works by blocking the reception of serotonin at these 5-HT3 receptors. News Articles on Palonosetron Big Buy: ADVENTRX's NDA and Financing News (AMEX:ANX) - 04 Jan 2010 Aloxi was the fourth drug in its class for chemotherapy induced nausea and vomiting. Still, Aloxi gained the market share lead in only 2 years. ... Small Cap Network Biovitrum Interim Report January 1st - September 30th, 2009 - Oct 21, 2009 Aloxi® was recommended by the Multinational Association for Supportive Care in Cancer and the European Society of Medical Oncology as the preferred 5-HT3 ... Ad-Hoc-News (Pressemitteilung) Riemser Arzneimittel AG auf gutem Kurs - Nov 10, 2009 Das gute Resultat lässt sich unter anderem auf sehr gute Leistungen des Onkologie-Force-Produktes Aloxi, ein starkes internationales Geschäft sowie ... Firmenpresse (Pressemitteilung) Brand Names/Synonyms: Aloxi is also known by the following brand names and/or synonymsAloxi; Onicit; Palonosetron; Raloxifene Drug Category: Aloxi is categorized under the following by the FDA: Antiemetics; ATC:A04AA Dosage Forms: Not Available Absorption: Not Available Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: Not Available |
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