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AlupentThis page contains recent news articles, when available, and an overview of Alupent but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Alupent (when available) Metaproterenol, a synthetic amine, is structurally and pharmacologically similar to isoproterenol. Metaproterenol is used exclusively as a bronchodilator. The pharmacologic effects of beta adrenergic agonist drugs, such as Metaproterenol, are at least in part attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic- 3',5'- adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. For the treatment of Bronchospasm; Chronic bronchitis; Asthma; Emphysema Mechanism Of Action: Metaproterenol is a moderately selective beta(2)-adrenergic agonist that stimulates receptors of the smooth muscle in the lungs, uterus, and vasculature supplying skeletal muscle, with minimal or no effect on alpha-adrenergic receptors. Intracellularly, the actions of metaproterenol are mediated by cAMP, the production of which is augmented by beta stimulation. The drug is believed to work by activating adenylate cyclase, the enzyme responsible for producing the cellular mediator cAMP. News Articles on Metaproterenol Bleibe im Lande und wehre dich täglich - Nov 9, 2009 Der gelernte DDR-Bürger wusste damit umzugehen, der HNO-Arzt erhielt von mir Flucinarsalbe gegen Alupent oder Berotec-Asthmaspray. ... Ärzte Zeitung What treatments work for bronchiolitis? - Jan 21, 2009 Examples include salbutamol (Ventolin, Airomir), orciprenaline (Alupent), adrenaline, ipratropium bromide (Atrovent) and aminophylline. guardian.co.uk, Brand Names/Synonyms: Alupent is also known by the following brand names and/or synonyms: Alotec; Alupent; CHEMBANK1252; Metaprel; Metaproterenol; Metaproterenol Polistirex; Metaproterenol Polistirex [Usan]; Metaproterenol Sulfate; Novasmasol; ORCIPRENALINE; Orciprenalina [Inn-Spanish]; Orciprenalinum [Inn-Latin]; Prometa Drug Category: Alupent is categorized under the following by the FDA: Tocolytic Agents; Bronchodilator Agents; ATC:R03AC Dosage Forms: Inhalation Absorption: 3% (oral bioavailability of 40%) Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: 5-[1-hydroxy-2-(1-methylethylamino)ethyl]benzene-1,3-diol |
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