Aminosalicylic Acid

This page contains recent news articles, when available, and an overview of Aminosalicylic Acid but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Aminosalicylic Acid (when available)

Pharmacology and use:
Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Zidovudine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated. For the treatment of Human immunovirus (HIV) infections

Mechanism Of Action:
Zidovudine, a structural analog of thymidine, inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA.

News Articles on Zidovudine

Shire Presents Results of Five Lialda(R) (mesalamine) Analyses at ACG 2009 ...  -  ‎Oct 26, 2009‎
Nasdaq: SHPGY), the global specialty biopharmaceutical company, presented the results of three 5-aminosalicylic acid (5-ASA) persistency analyses at ACG ... Reuters

Real-World Patient Experiences on Medications for Chronic Conditions ...  -  ‎Oct 26, 2009‎
...perceptions and experiences of patients beginning and continuing a new course of 5-aminosalicylic acid (5-ASA), the mainstay of treatment for UC. ... Reuters

Procter & Gamble Pharmaceuticals Launches Asacol(R) HD (mesalamine ...  -  ‎Jul 7, 2009‎
P&GP is also the maker of Asacol(R) (mesalamine) 400 mg delayed-release tablets, the number one most-prescribed oral 5-aminosalicylic acid (5-ASA) therapy. PR Newswire (press release)

Should You Go For Breast Cancer Screening?  -  ‎Apr 2, 2009‎
Drug treatment with streptomycin, isoniazid and PAS, the sodium salt of para-aminosalicylic acid, helped my body to overcome the TB, but since the bad HULIQ

Grossesse et maladies inflammatoires cryptogénétiques intestinales  -  ‎Mar 12, 2009‎
Influence of salazosulphapyridine and 5-aminosalicylic acid on seminal qualities and male sex hormones. Scand J Gastroenterol 1988 ; 23 : 1100-4. John Libbey Eurotext

FDA Approvals: Apriso, Promacta, Treanda  -  Dec 4, 2008
...the product's patented Intellicor delivery system is the first and only to combine delayed and extended release of 5-aminosalicylic acid (5-ASA) — its Medscape

Study: 5-ASA Not Useful in Colon Cancer Prevention  -  Nov 19, 2008
BETHESDA, Md. — Study findings recently published in Clinical Gastroenterology and Hepatology failed to show that the use of 5-aminosalicylic acid (5-ASA) EndoNurse,

Cephalon's Treanda OK'd for Second Cancer Indication  -  Nov 3, 2008
...a locally acting 5-aminosalicylic acid, to maintain the remission of ulcerative colitis, a chronic inflammatory disease of the colon or large intestine, TMCnet

Predictores de recaída de la enfermedad de Crohn  -  Nov 4, 2008
Controlled trial of oral 5- aminosalicylic acid for the prevention of early relapse in Crohn’s disease. Aliment Pharmacol 1997;11:845–52. 4. Intramed.net (Suscripción),

Effectiveness Confirmed for Multi-Drug Treatment of XDR-TB  Aug 25, 2008
...but 80% or more of XDR-TB patients received capreomycin, ofloxacin, cycloserine, para-aminosalicylic acid, or ethionamide or prothionamide.MedPage Today,

Mild to Moderate Crohn's Disease in Children: High Dose Oral 4 ...  Sep 3, 2008
AP classes aren'ta part of NJ school landscape Want to dig deeper? SmartBrief brings you news, research, and other information related to this issue.SmartBrief,

Traitement des tuberculoses résistantes, les antibiotiques utilisés  Sep 8, 2008
Les antibiotiques les plus utilisés chez les 48 tuberculeux XDR ont été : la cyclosérine, l'éthionamide, le PAS ou para-aminosalicylic acid,Maroc Info Com,

Chronic Nonhealing Ulcer of the Right Thumb With Multiple ...  -  Jul 22, 2008
2-4 Special stains, such as para-aminosalicylic acid or Gomori-methenamine silver, can be used to visualize these cigar-shaped fungi on biopsy specimens. Ortho SuperSite,

Single-Dose MMX Mesalazine May Be Effective for Ulcerative Colitis  -  Jun 19, 2008
..."MMX mesalazine is a once-daily, high-strength (1.2 g/tablet) formulation of 5-aminosalicylic acid [5-ASA]. This study evaluated the safety and efficacy of Medscape (subscription)

Hepatotoxicity of Pyrazinamide: Cohort and Case-Control Analyses  -  Jun 17, 2008
...of pyrazinamide at a dosage of 3 g daily with isoniazid showed a high risk of hepatitis in comparison with isoniazid and para- aminosalicylic acid (12). RedOrbit,

Alaven Pharmaceutical Introduces Kit for UC Patients  -  Jun 9, 2008
5-aminosalicylic acid enema in the treatment of distal ulcerative colitis, proctosigmoiditis, and proctitis. Gastroenterology. 1987;92(6):1894-1898. RedOrbit,

Mesalamine Induces Mucosal Healing in Ulcerative Colitis in ...  -  May 28, 2008
...high-strength (1.2 g/tablet) formulation of 5-aminosalicylic acid/mesalamine (marketed as Lialda in the United States, Mezavant XL in the United Kingdom Medscape (subscription)

Anti-TNF Therapy for Crohn's Disease: Expert Interview With David ...  -  May 27, 2008
We know from studies done with 5-aminosalicylic acid in ulcerative colitis that adherence with prescribed treatment is important for maintaining remission. Medscape (subscription)

Ajinomoto to Obtain Rights for Colon Ulcer Drug from German Firm  -  Apr 7, 2008
The drug, 5-aminosalicylic acid, marketed as Salofalk and Granu-Stix by Dr. Falk Pharma in Europe, comes in a form of granulated powder, and only needs to Japan Corporate News (press release),

Brand Names/Synonyms:
Aminosalicylic Acid is also known by the following brand names and/or synonyms:
A 1909; Amino-Pas; Aminopar; Aminosalicylic Acid; Aminox; Apacil; Apas; Deapasil; Entepas; Ferrosan; Gabbropas; Hellipidyl; Kyselina P-Aminosalicylova; NIH 2939; NSC 2083; Neopasalate; Osacyl; P-Aminosalicylic Acid; PAS; PAS-C; PASK; Pamacyl; Pamisyl; Para-Amino Salicylic Acid; Para-Pas; Paramycin; Parasal; Parasalicil; Parasalindon; Pasa; Pasalon; Pasara; Pascorbic; Pasdium; Pasem; Paser; Pasmed; Pasnodia; Pasolac; Propasa; Rezipas; Sanipirol-4; Sanipriol-4

Drug Category:
Aminosalicylic Acid is categorized under the following by the FDA: Antituberculosis Agents; ATC:J04AA01

Dosage Forms:
Packet of coated granules

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
4-amino-2-hydroxy-benzoic acid

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