Amiodarone

This page contains recent news articles, when available, and an overview of Amiodarone but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Amiodarone
(when available)

Pharmacology and use:
Zileuton is an orally active inhibitor of 5-lipoxygenase, the enzyme that catalyzes the formation of leukotrienes from arachidonic acid. Zileuton is indicated for the prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older. For the prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older

Mechanism Of Action:
Zileuton is a specific inhibitor of 5-lipoxygenase and thus inhibits leukotriene (LTB4, LTC4, LTD4, and LTE4) formation. Both the R(+) and S(-) enantiomers are pharmacologically active as 5-lipoxygenase inhibitors in in vitro systems. Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth muscle contraction. These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients.

News Articles on Zileuton

VTACH: Ablation before ICD reduces recurrence of ventricular tachycardia  -  04 Jan 2010
The current standard of care, an ICD, doesn't cure VT but only treats it after the episode occurs, and so amiodarone is typically prescribed. ... TheHeart.Org

Cardiome Pharma says vernakalant (iv) beats amiodarone in European study  -  ‎Dec 17, 2009‎
...(TSX:COM) said Thursday that a Phase 3 study in Europe found vernakalant (iv) performed better than amiodarone in treating atrial fibrillation or an ... The Canadian Press

NICE leans away from dronedarone for atrial fib  -  ‎Dec 30, 2009‎
London, UK - Vaunted as an amiodarone alternative for atrial fibrillation and approved in North America, the European Union, and other places, ... TheHeart.Org

Catheter Ablation Before ICD Implant Improves Outcomes  -  ‎Jan 1, 2010‎
Overall, 35% of patients in both groups were taking amiodarone at randomization. At two years, the estimate of survival free from either ventricular ... MedPage Today

Sanofi's Multaq Fails to Win UK Cost Agency Backing  -  ‎Dec 24, 2009‎
...dose of Multaq would be 2.25 pounds -- 45 times more expensive than an existing generic medicine amiodarone, which costs around 5 pence a day. ... New York Times

Benzinga's Top Pre- Market Gainers (SENO, TTWO, RIMM, SMOD, CRME)  -  ‎Dec 18, 2009‎
Yesterday, CARDIOME PHARMA announced that the Phase 3 European Comparator Study evaluating vernakalant (iv) versus amiodarone met its primary endpoint. ... Benzinga

Real Life Example Of Pharmacy Mistake  -  ‎Dec 20, 2009‎
Amiodarone, a drug used to treat irregular rapid heartbeat when other drugs fail. In following the dosing instructions for the flu medication, ... InjuryBoard.com (blog)

Challenges of Interpreting Results From Analyses That Use Extensive Claims Data  -  ‎Dec 14, 2009‎
Although our approach did not specifically exclude patients receiving amiodarone or pressors, it did exclude patients with a wide range of contraindications ... Annals of Internal Medicine

Avoid a bad drug trip  -  ‎Dec 11, 2009‎
Examples include: c Patients taking Zocor (simvastatin) in doses higher than 20 milligrams along with Cordarone (amiodarone) (prescribed to correct abnormal ... Washington Times

Local Resident, Holly Orman, Recently Had A Heart Transplant  -  ‎Dec 19, 2009‎
She was given an A/V sequential pacemaker and placed on amiodarone and deteriorated. Then a Biventricular pacemaker was placed in Nov. ... Pine Tree

HEART TO HEART: When the heart dances out of rhythm  -  ‎Dec 22, 2009‎
Various drugs are used to convert AF back into normal sinus rhythm such as amiodarone and propafenone but they usually work if the onset of AF is recent. ... Malay Mail

Doctors to perform emergency surgery on Brazil boy with needles in body  -  ‎Dec 18, 2009‎
...(TSX:COM) said Thursday that a Phase 3 study in Europe found vernakalant (iv) performed better than amiodarone in treating atrial fibrillation or an ... Metro Canada - Edmonton

심방세ë?™ 치료제 시장 7ë°° 성장  -  ‎Jan 3, 2010‎
...ë˜?한 ë©€íƒ?ì?€ ì •ìƒ? 굴리듬 유지 표준요법ì?¸ '코다론'(Cordarone, amiodarone)ì—? 비해서ë?„ ê°‘ìƒ?ì„  ë°? í?? ë?…성 부작용 ë©´ì—?서 ë?”ìš± 안전해 2012년까지 새로운 표준요법 ... 디지틀보사

Une AMM européenne pour Multaq dans la FA  -  ‎Dec 11, 2009‎
ADONIS, ERATO, ATHENA — un essai comparatif contre l'amiodarone (DIONYSOS), et un essai contre placebo mené chez des insuffisants cardiaques récemment ... theheart.org/fr

Ceres drugstore gives child heart meds by mistake  -  ‎Nov 10, 2009‎
Oseltamivir is what the label read, but instead the Walgreens pharmacy filled her bottle with Amiodarone, a heart medication. November 9, 2009 (BART AH ... Modesto Bee

Death of pensioner caused by rare reaction to medication  -  ‎Nov 11, 2009‎
Freda Oulsnam was prescribed a medicine called Amiodarone following a heart valve replacement operation. Normally there are few adverse side effects but in ... Derby Evening Telegraph

Girl Gets Wrong Medicine After Pharmacy Mix-Up  -  ‎Nov 11, 2009‎
But by then the girl had taken two doses of amiodarone, a medicine for irregular heart beats. The girl is still being treated for a heart abnormality after ... WCPO

Cardiovascular connections: two-way street between heart and health  -  ‎Nov 4, 2009‎
Drugs used to control abnormal heart rhythms, especially amiodarone (Cordarone), can throw the thyroid out of whack. Liver: As befitting the largest ... Sun-Sentinel.com

What is the appropriate use of chronic medications in the perioperative setting?  -  ‎Nov 5, 2009‎
...the dose should be titrated to a heart rate <65 for optimal cardiac protection.1 Amiodarone has an exceptionally long half-life of up to 142 days. ... The Hospitalist Online

Novartis drug Tasigna(R) meets primary endpoint in pivotal trial against ...  -  ‎Oct 19, 2009‎
Concomitant strong CYP3A4 inhibitors The concomitant use of strong CYP3A4 inhibitors or anti-arrhythmic drugs (including, but not limited to amiodarone, ... Reuters

Looking for an ally? Take a pill  -  ‎Oct 29, 2009‎
...a person with diabetes,someone taking other drugs (particularly oral contraceptives, warfarin or other medicines that thin the blood, or amiodarone for ... BusinessWorld Online

Дронедарон или амиодарон при фибриллÑ?ции предÑ?ердий: непрÑ?мой Ñ?равнительный ...  -  ‎Oct 20, 2009‎
Предварительные результаты иÑ?Ñ?ледованиÑ? DIONYSOS (Efficacy & Safety of Dronedarone Versus Amiodarone for the Maintenance of Sinus Rhythm in Patients With ... Medicus Amicus

Có thần dược trị gan nhiá»…m mỡ?  -  ‎Oct 27, 2009‎
...nghiện rượu, viêm gan siêu vi, ảnh hưởng cá»§a má»™t số thuốc (corticoid, tamoxiphen, amiodarone,…) chứ không phải chỉ do ăn nhiá»?u dầu mỡ mà mắc bệnh. ... Báo điện tử Tuyên Quang

심방세ë?™ì—? 어설픈 ë?™ì¡°ìœ¨í™” '위험'  -  ‎Oct 27, 2009‎
...현재 드로네다론과 아미오다론ì?„ ì§?ì ‘ 비êµ?하는 Efficacy and Safety of Dronedarone versus Amiodarone for the Maintenance of Sinus Rhythm in Patients with ... 메디칼트리뷴

Brand Names/Synonyms:
Amiodarone is also known by the following brand names and/or synonymsAminodarone; Amiodarona; Amiodarona [Inn-Spanish]; Amiodarone; Amiodarone Base; Amiodarone Hcl; Amiodarone Hydrochloride; Amiodarone [Usan:Ban:Amiodarons; Amiodarone [Usan:Ban:Inn]; Amiodarons; Amiodaronum [Inn-Latin]; Amiodaronumhydrochloride; Amjodaronum; Base; Cordarone; Cordarone I've.; Cordarone Intravenous; L 3428; L-3428; L. 3428; Labaz; Pacerone; Pms-Amiodarone; Uro-Septra

Drug Category:
Amiodarone is categorized under the following by the FDA: Vasodilator Agents; Antiarrhythmic Agents; Enzyme Inhibitors; ATC:C01BD01

Dosage Forms:
TABLET; LIQUID; SOLUTION

Absorption:
Slow and variable; about 20 to 55% of an oral dose is absorbed

Interactions:
[an error occurred while processing this directive]



Chemical IUPAC Name:
(2-butylbenzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodo-phenyl]-methanone





Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy