Amoxapine

This page contains recent news articles, when available, and an overview of Amoxapine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Amoxapine (when available)

Pharmacology and use:
Amoxapine is a tricyclic antidepressant. It was thought that tricylic antidepressants work by inhibiting the re-uptake of the neurotransmitters norepinephrine and serotonin by nerve cells. However, this response occurs immediately, yet mood does not lift for around two weeks. It is now thought that changes occur in receptor sensitivity in the cerebral cortex and hippocampus. The hippocampus is part of the limbic system, a part of the brain involved in emotions. Presynaptic receptors are affected: a1 and b1 receptors are sensitized, a2 receptors are desensitised (leading to increased noradrenaline production). Tricyclics are also known as effective analgesics for different types of pain, especially neuropathic or neuralgic pain. A precise mechanism for their analgesic action is unknown, but it is thought that they modulate anti-pain opioid systems in the CNS via an indirect serotonergic route. They are also effective in migraine prophylaxis, but not in abortion of acute migraine attack. The mechanism of their anti-migraine action is also thought to be serotonergic. For the relief of symptoms of depression in patients with neurotic or reactive depressive disorders as well as endogenous and psychotic depressions. It is indicated for depression accompanied by anxiety or agitation.

Mechanism Of Action:
Amoxapine acts by decreasing the reuptake of norepinephrine and serotonin (5-HT).

News Articles on Amoxapine

COMMENTARY: Where Are the Smith Brothers When We Need Them?  -  ‎Jun 26, 2009‎
Amoxapine. Amlodipine. Nifedipine. Nortrilen. Zestril. Nalorex. Imagine how much more fun it would be if you had to search through half a dozen medicine HNN Huntingtonnews.net

But how might Demerol/meperidine have caused cardiac arrest, the ...  -  ‎Jun 26, 2009‎
...[7760] Examples of CNS depressants include amitriptyline; amoxapine; anxiolytics, sedatives, and hypnotics [5610]; carisoprodol; clomipramine; clozapine; ScienceBlogs

People With Dementia Should Avoid Certain Drugs  -  Jun 27, 2008
Antidepressants Tricyclic Antidepressants, such as Amitriptyline (Elavil), Amoxapine (Asendin), Clomipramine (Anafranil), Doxepin (Sinequan), RedOrbit,

Neural Stimulation Successfully Treats Depression in Patients With ...  -  02 Jun 2008
...methylphenidate, buspirone, amoxapine, flupenthixol, carbamazepine, topiramate, and valproic acid. All had failed to provide any sustained benefit. Am J Psychiatry (subscription)

Hydrocodone Online  -  May 8, 2008
Severe dietary ways (rash; hives; itching; hydrocodone online breathing; amoxapine in the chest; signing of the mouth, face, lips, or tongue); command pain; Shell Security,

Where are the Smith Brothers when we need them?  -  Feb 28, 2008
Amoxapine. Amlodipine. Nifedipine. Nortrilen. Zestril. Nalorex. Imagine how much more fun it would be if you had to search through half a dozen medicine Evening Sun (subscription),

New test shows source of disease side-effects  -  Feb 24, 2008
Other drugs that resembled statins in their activity in mitochondria included amoxapine, cyclobenzaprine, griseofulvin, pentamidine, paclitaxel, propafenone Scientific American

New Study Explains Side Effects of Popular Cholesterol Drugs  -  Feb 25, 2008
Other drugs that resembled statins affecting mitochondria included amoxapine, cyclobenzaprine, griseofulvin, pentamidine, paclitaxel, propafenone, RedOrbit,

Brand Names/Synonyms:
Amoxapine is also known by the following brand names and/or synonyms:
Amoxapine; Amoxepine; Ascendin; Asendin; Asendis; CL-67.772; Demolox; Moxadil

Drug Category:
Amoxapine is categorized under the following by the FDA: Antidepressants; Norepinephrine-Reuptake Inhibitors; ATC:N06AA17

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
Not Available

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