Angiomax

This page contains recent news articles, when available, and an overview of Angiomax but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Angiomax
(when available)

Pharmacology and use:
Angiomax directly inhibits thrombin by specifically binding both to the catalytic site and to the anion-binding exosite of circulating and clot-bound thrombin. Thrombin is a serine proteinase that plays a central role in the thrombotic process, acting to cleave fibrinogen into fibrin monomers and to activate Factor XIII to Factor XIIIa, allowing fibrin to develop a covalently cross-linked framework which stabilizes the thrombus; thrombin also activates Factors V and VIII, promoting further thrombin generation, and activates platelets, stimulating aggregation and granule release For treatment of heparin-induced thrombocytopenia

Mechanism Of Action:
Inhibits the action of thrombin by binding both to its catalytic site and to its anion-binding exosite.

News Articles on Bivalirudin

Medicines Co. Suing Teva, Pliva Again Over Patent  -  04 Jan 2010
Specifically, it is suing over the '343' patent. Medicines is already involved in lawsuits with the same companies over a separate patent on Angiomax. ABC News

Medicines Co. Buys Heart Drug From Pfizer: BioBuzz  -  ‎Dec 23, 2009‎
...s primary product is Angiomax, a blood thinner used by doctors during angioplasty and cardiac stenting procedures. However, Angiomax faces generic ... TheStreet.com

The Medicines Company Announces Option Grants Under NASDAQ Marketplace Rule 5635  -  ‎Dec 15, 2009‎
The Company markets Angiomax® (bivalirudin) in the United States and other countries for use in patients undergoing coronary angioplasty, and Cleviprex® ... CNNMoney.com (press release)

DotW: Last-Minute Shopping  -  ‎Dec 23, 2009‎
TMC needs to add critical-care products to a portfolio threatened by next year's patent expiration of top seller Angiomax. ... The IN VIVO Blog (blog)

Medicines Co. amps up Angiomax lobbying  -  ‎Oct 23, 2009‎
...s case, the full-court press isn't for reform, but for something much more specific: a patent extension on its anti-coagulant Angiomax. ... FiercePharma

Medicines Company Reports Operating Results (10-Q)  -  ‎Nov 9, 2009‎
US Food and Drug Administration intends to approve its first product, Angiomax, for use in the treatment ofpatients with unstable angina undergoing coronary ... GuruFocus.com

Medicines Co. gets positive EU panel result  -  ‎Oct 23, 2009‎
The European Medicines Agency will make a final decision on the potential approval. In the US, the drug is sold under the name Angiomax. Forbes

Medicines Co. Q3 Loss Narrows; Cuts FY09 EPS View - Update  -  ‎Oct 28, 2009‎
Angiomax US sales increased by 9% to $92.2 million from $85 million in the third quarter of 2008. Angiomax/Angiox international net revenue was $5.5 million ... RTT News

The Medicines Company Reports Third Quarter 2009 Financial Results  -  ‎Nov 1, 2009‎
Angiomax US sales increased by 9% to $92.2 million in the third quarter of 2009 compared to $85.0 million in the third quarter of 2008. ... PR-CANADA.net (press release)

Cleviprex Results Reported From Study in Patients With Intracerebral Hemorrhage  -  ‎Nov 12, 2009‎
The Company markets Angiomax® (bivalirudin) in the United States and other countries for use in patients undergoing coronary angioplasty, ... CNNMoney.com (press release)

Armey says he mastered dual roles of lobbyist, conservative leader  -  ‎Oct 29, 2009‎
Armey's biggest client at DLA Piper, New Jersey drug maker Medicines Co., lobbied mostly to extend a patent on its blood thinner Angiomax, according to ... Dallas Morning News

EC approves Merck, Schering-Plough merger; Swine flu market on the rise;  -  ‎Oct 23, 2009‎
...s case, the full-court press isn't for reform, but for something much more specific: a patent extension on its anti-coagulant Angiomax. ... FierceBiotech

The Medicines Company Announces Positive CHMP Opinion for Angiox® (Bivalirudin ...  -  ‎Oct 23, 2009‎
Angiox is marketed as Angiomax in the USA and other territories. About The Medicines Company The Medicines Company (Nasdaq: MDCO) is focused on advancing ... Reuters

New approaches to eptifibatide administration  -  ‎Nov 2, 2009‎
Patients with recent STEMI (<48 hours); visible thrombus; bivalirudin (Angiomax, The Medicines Company) treatment; unprotected left main; use of ablative or ... Cardiology Today

The Medicines Company gibt positive Empfehlung des CHMP für Angiox ...  -  ‎Oct 23, 2009‎
Angiox wird in den USA und anderen Territorien als Angiomax vermarktet. Über The Medicines Company The Medicines Company (NASDAQ: MDCO) ist auf die ... Reuters

—Aprobación basada en los datos del ensayo de referencia HORIZONS-AMI—  -  ‎Oct 23, 2009‎
Angiox se comercializa como Angiomax en los Estados Unidos y otros territorios. El principal objetivo de The Medicines Company (Nasdaq: MDCO) es progresar ... Business Wire (press release)

The Medicines Company annonce un avis favorable pour Angiox (Bivalirudine ...  -  ‎Oct 23, 2009‎
Angiox est commercialisé sous le nom d`Angiomax aux Etats-Unis et dans d`autres territoires. A propos de The Medicines Company The Medicines Company (MDCO ... Reuters

—Aprovação baseada nos dados do ensaio clínico de referência HORIZONS-AMI—  -  ‎Oct 23, 2009‎
Angiox é comercializado como Angiomax nos EUA e em outras regiões. The Medicines Company (Nasdaq: MDCO) dedica-se ao avanço do tratamento de pacientes de ... Business Wire (press release)

Medicineså…¬å?¸å®£å¸ƒï¼ŒCHMP核准Angiox? (比ä¼?å?¢å®š)用于接å?—急诊心è„?手术的心è„?ç—…å?‘作患者  -  ‎Oct 26, 2009‎
Angiox是美国和其他地区的商å“?å??为Angiomax。 Medicineså…¬å?¸(Nasdaq: MDCO)专注于为全ç?ƒåŒ»é™¢å¸‚场æ??供具有æˆ?本效益的创新è?¯ç‰©ï¼Œä»¥æ­¤æŽ¨åЍå?±é‡?患者的治疗。 ... 凤凰网

Medicineså…¬å?¸å®£ä½ˆï¼ŒCHMP核准Angiox® (比ä¼?盧定) 用於接å?—急診心臟手術的心臟病發作患者  -  ‎Oct 26, 2009‎
Angiox在美國和其他地å?€çš„商å“?å??稱為Angiomax。 Medicineså…¬å?¸(Nasdaq: MDCO) 專注於為全ç?ƒé†«é™¢å¸‚å ´æ??供具有æˆ?本效益的創新藥物,以此推動é‡?症患者的治療。 ... 中央通訊社

ザ・メディシンズ・カンパニーã€?欧州CHMPã?Œç·Šæ€¥æ‰‹è¡“ã‚’å?—ã?‘る心臓発作患者ã?¸ã?®Angiox ...  -  ‎Oct 26, 2009‎
Angioxã?¯ç±³å›½ã??ã?®ä»–ã?®åœ°åŸŸã?§Angiomaxã?®å??ç§°ã?§è²©å£²ã?•れã?¦ã?„ã?¾ã?™ã€‚ ザ・メディシンズ・カンパニー(Nasdaq: MDCO)ã?¯ã€?é?©æ–°çš„ã?§ã€?コスト効果ã?®é«˜ã?„医薬å“?を世界ã?®ç—…院 ... Business Wire (press release)

Brand Names/Synonyms:
Angiomax is also known by the following brand names and/or synonymsAngiomax; Angiomax (Medicines Co or MDCO)

Drug Category:
Angiomax is categorized under the following by the FDA: Anticoagulants; Antithrombotic Agents

Dosage Forms:
Not Available

Absorption:
Not Available

Interactions:
Not Available



Chemical IUPAC Name:
FPRPGGGGNGDFEEIPEEYL





Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy