Antithymocyte globulin

This page contains recent news articles, when available, and an overview of Antithymocyte globulin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Antithymocyte globulin (when available)

Pharmacology and use:
This immunosuppressive product, obtained by immunization of rabbits with human thymocytes, contains cytotoxic antibodies directed against antigens expressed on human T-lymphocytes. This reduces the host immune response against tissue transplants or organ allografts. For prevention of renal transplant rejection

Mechanism Of Action:
Binds to multiple, T-cell specific antigens leading to T-lymphocyte cell death via complement mediated cytotoxicity or apoptosis.

News Articles on Antithymocyte globulin

Affordable anti-rejection drug effective - ‎Oct 19, 2009‎
...antithymocyte globulin, which costs about four times more for its multi-dose treatment than alemtuzumab, and is marketed under the name Thymoglobulin. ... United Press International

Brand Names/Synonyms:
Antithymocyte globulin is also known by the following brand names and/or synonymsThymoglobulin; Thymoglobulin (SangStat Medical; Genzyme)

Drug Category:
Antithymocyte globulin is categorized under the following by the FDA: Immunomodulatory Agents; unclassified therapeutic agents (92:00.00)

Dosage Forms:
POWDER FOR SOLUTION

Absorption:
Not Available

Interactions:
Not Available

Chemical IUPAC Name:
Rabbit anti-thymocyte globulin

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