Arestin

This page contains recent news articles, when available, and an overview of Arestin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Arestin
(when available)

Pharmacology and use:
Minocycline, the most lipid soluble and most active tetracycline antibiotic, is, like doxycycline, a long-acting tetracycline. Minocycline's effects are related to the inhibition of protein synthesis. Minocycline is used to treat nongonococcal urethritis, mucopurulent cervicitis, acne vulgaris, and rheumatoid arthritis and some othet infections. Because of its lipid solubility, minocycline is able to eradicate the meningococcal carrier state in tears and saliva. For the treatment of infections caused by susceptible strains of microorganisms, such as Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox and tick fevers caused by Rickettsiae, Upper respiratory tract infections caused by Streptococcus pneumoniee; For the treatment of asymptomatic carriers of Neisseria meningitidis

Mechanism Of Action:
Minocycline passes directly through the lipid bilayer or passively diffuses through porin channels in the bacterial membrane. Tetracyclines like minocycline bind to the 30 S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis.

News Articles on Minocycline

The Heat is On ... Protocols help the sizzle fizzle!  -  ‎Dec 31, 2009‎
2, 3, 30, and 31with subgingival irrigation, and Arestin was placed in periodontal pockets (D4381) of 5 mm with BOP. The patient scheduled her next visit to ... RDH

Dentist enjoys the people and the variety her practice brings her  -  ‎Dec 28, 2009‎
This year we added digital X-rays; Vizilite, which checks for oral cancer; Arestin, an antibiotic for gum disease; and Diagnodent, a device used to check ... Muscatine Journal

Part III, Profitability and Peace of Mind in a Down Economy  -  ‎Dec 9, 2009‎
Locally Applied Antimicrobials (example ArestinĀ® and others) are being used more and more on SRP patients. The Average has now exceeded two teeth for total ... Dentistry IQ

The HMO experience  -  ‎Oct 30, 2009‎
...anesthesia, scaling/ultrasonic therapy, Peridex irrigation, any Arestin needed, OHI, and breaking down my operatory, and sterilization. ... RDH

Brand Names/Synonyms:
Arestin is also known by the following brand names and/or synonymsAlti-Minocycline; Apo-Minocycline; Arestin; BRN 3077644; CL 59806; DYNACIN; Dynacin; Gen-Minocycline; HSDB 3130; Klinomycin; MINOCYCLINE; Minociclina [Inn-Spanish]; Minocin; Minocyclin; Minocycline; Minocycline Hcl; Minocycline [Usan:Ban:Inn]; Minocyclinum [Inn-Latin]; Minocyn; Minomycin; Novo-Minocycline; Vectrin

Drug Category:
Arestin is categorized under the following by the FDA: Anti-bacterial Agents; Tetracyclines; ATC:A01AB23; ATC:J01AA08

Dosage Forms:
Capsules; Subgingival (sustained-release); IV Injection;

Absorption:
rapidly absorbed from the gastrointestinal tract

Interactions:
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Chemical IUPAC Name:
2-(amino-hydroxy-methylidene)-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4,4a,5,5a,6,12a-hexahydrotetracene-1,3,12-trione





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