Aripiprazole

This page contains recent news articles, when available, and an overview of Aripiprazole but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Aripiprazole
(when available)

Pharmacology and use:
Aripiprazole is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Aripiprazole is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), dopamine Type 2 (D2), 1 and 2 adrenergic, and H1 histaminergic receptors. Aripiprazole acts as an antagonist at other receptors, but with lower potency. Antagonism at receptors other than dopamine and 5HT2 with similar receptor affinities may explain some of the other therapeutic and side effects of Aripiprazole. Aripiprazole's antagonism of histamine H1 receptors may explain the somnolence observed with this drug. Aripiprazole's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug. For the treatment of schizophrenia

Mechanism Of Action:
Aripiprazole exhibits high affinity for dopamine D2 and D3, serotonin 5-HT1A and 5- HT2A receptors, moderate affinity for dopamine D4, serotonin 5-HT2C and 5-HT7, alpha1-adrenergic and histamine H1 receptors and moderate affinity for the serotonin reuptake pump. Aripiprazole has no appreciable affinity for cholinergic muscarinic receptors. Aripiprazole functions as a partial agonist at the dopamine D2 and the serotonin 5-HT1A receptors, and as an antagonist at serotonin 5-HT2A receptor.

News Articles on Aripiprazole

Aripiprazole Generally Safe, Tolerable for Children With Autism-Related ...  -  ‎Nov 12, 2009‎
The findings in the original placebo-controlled trials showed that aripiprazole was superior to placebo in reducing irritable and aggressive symptoms in ... DG News

Use Of Antipsychotic Medications By Children And Adolescents Associated With ...  -  ‎Oct 28, 2009‎
Patients were treated with the antipsychotic medications aripiprazole, olanzapine, quetiapine, or risperidone for 12 weeks. After a median (midpoint) of ... Science Daily (press release)

Generic Name: Aripiprazole, Arizol, Arlemide, Brisking, Ilimit, Irazem, Real One  -  ‎Nov 11, 2009‎
Abilify (generic name: Aripiprazole; brand names include: Arizol / Arlemide / Brisking / Ilimit / Irazem) is an atypical antipsychotic. ... Pattaya Daily News

Kids using anti-psychotic drugs gained weight: study  -  ‎Oct 28, 2009‎
...well as mood disorders, are often prescribed second-generation antipsychotic medications such as aripiprazole, olanzapine, quetiapine, and risperidone. ... AFP

Can Balloon Boy finally shoot down our obsession with fame?  -  ‎Oct 20, 2009‎
...ultimately, the kind of entertainment suitable only to a mental patient crammed full of Aripiprazole 9 or any other third-generation anti-psychotic. ... Globe and Mail

Children Gain Weight on Antipsychotic Medications  -  ‎Oct 31, 2009‎
Average gain was as follows: 18.7 pounds with onanzapine, 13.7 pounds with quetiapine, 11.7 pounds with risperidone, and 9.7 pounds with aripiprazole. ... Healia Health (blog)

B-MS posts strong sales for most of its drugs  -  ‎Oct 23, 2009‎
Biopharmaceutical turnover was up 6% to $4.80 billion, driven by Plavix (clopidogrel), up 8% to $1.55 billion, while sales of Abilify (aripiprazole) climbed ... Pharma Times

Bipolar drug market “to plummet from 2011â€?  -  ‎Nov 10, 2009‎
Bristol-Myers Squibb/Otsuka's Abilify (aripiprazole) and Pfizer's Geodon (ziprasidone), according to the study, from Decision Resources. ... Pharma Times

BristolMyers Squibb Company Reports Operating Results (10-Q)  -  ‎Oct 22, 2009‎
PLAVIX* (clopidogrel bisulfate) and ABILIFY* (aripiprazole) continue to drive sales growth with sales increases of 8% and 16% for the three months ended ... GuruFocus.com

This Week in JAMA  -  ‎Oct 27, 2009‎
Correll and colleagues (SEE ARTICLE) assessed the association of 12-week treatment with aripiprazole, olanzapine, quetiapine, or risperidone with body ... Journal of American Medical Association (subscription)

Antipsychotic Drugs Can Cause Rapid Weight Gain in Kids  -  ‎Nov 3, 2009‎
Zyprexa or olanzapine made by Eli Lilly, Abilify or aripiprazole made by Bristol-Myers Squibb, and Seroquel or quetiapine made by AstraZeneca. ... Fars News Agency

Antipsychotic Drugs Put Kids at Risk  -  ‎Nov 1, 2009‎
...patients on average had gained 18.7 pounds with olanzapine, 13.4 pounds with quetiapine, 11.7 pounds with risperidone and 9.7 pounds with aripiprazole. ... Ivanhoe

Anti-Psychotic Medications Associated With Childhood Weight Gain  -  ‎Oct 28, 2009‎
Specifically, an average of 18.7 pounds with olanzapine, by 13.4 pounds with quetiapine, by 11.7 pounds with risperidone and by 9.7 lbs. with aripiprazole, ... Gant Daily

On the Pulse - 6th November 2009  -  ‎Nov 6, 2009‎
...all four drugs studied were associated with significant weight gains, from a mean of 4.4 kg with aripiprazole to 8.8 kg with olanzapine. ... OnMedica

New systematic study for managing treatment-resistant bipolar depression  -  ‎Oct 27, 2009‎
...carbamazepine 800 mg, aripiprazole 30 mg, olanzapine 5 mg (intolerant), ziprasidone 160 mg (intolerant), fluoxetine 80 mg, duloxetine 90 mg, ... News-Medical.net

New Report Just Published Blood-Brain Barrier: Bridging Options for Drug ...  -  ‎Oct 23, 2009‎
...for treatment of depression) and Bristol-Myers Squibb's/Otsuka's Abilify (aripiprazole, for treatment of bipolar disorder and schizophrenia). ... Live-PR.com (Pressemitteilung)

Les anti-psychotiques pour enfants créent des problèmes de poids  -  ‎Oct 28, 2009‎
Et il n'y avait pas de changements importants observés pour l'aripiprazole ou dans les groupes témoins non traités, selon les chercheurs. ... Le blog bébé (Blog)

Les antipsychotiques causent un rapide et important gain de poids chez les jeunes  -  ‎Oct 27, 2009‎
...pour la première fois, un des quatre antipsychotiques Abilify (aripiprazole), Risperdal (risperidone), Seroquel (quetiapine) ou Zyprexa (olanzapine). ... PsychoMédia

Des antipsychotiques provoquent l'obésité chez les enfants et les adolescents  -  ‎Nov 2, 2009‎
Ils se sont tous vus prescrire quatre différents types d'antipsychotiques à savoir l'aripiprazole, l'olanzapine, le quetiapine et le risperidone pendant 12 ... Algérie Soir

Evidence for the Partial Dopamine-Receptor Agonist Aripiprazole as ...  -  ‎Aug 17, 2009‎
Although a number of studies claim that aripiprazole is a prolactin-sparing antipsychotic drug that may even lower prolactin levels, there has not been an Psychosomatics (subscription)

Treatment of Narcolepsy Complicated by Psychotic Symptoms  -  ‎Aug 17, 2009‎
For this reason, having accomplished 2 weeks of medication with olanzapine, we decided to suspend it gradually and prescribed aripiprazole in doses titrated Psychosomatics (subscription)

New Antipsychotic Eases Schizophrenia Symptoms  -  ‎Aug 27, 2009‎
..."Up until now the drugs that have had better side effect profiles, like ziprasidone [Geodon] and aripiprazole [Abilify], have not been as broadly and MedPage Today

Ask the Expert: Psychosomatic Medicine/Delirium  -  ‎Aug 28, 2009‎
Limited data are available for olanzapine, aripiprazole, and perospirone. Avoid clozapine and ziprasidone. Note: antipsychotics should be used with caution Focus (subscription)

Iloperidone Approved as “Second-Generationâ€? Benefits Debated  -  ‎Aug 24, 2009‎
The effects on overall symptoms of the other 5 studied (aripiprazole, quetiapine, sertindole, ziprasidone, and zotepine) were not significantly different Psychiatric Times

FDA Panel OKs 3 Antipsychotic Drugs for Pediatric Use, Cautions ...  -  ‎Aug 25, 2009‎
DB01124, DB00334, DB00246) Two atypical antipsychotic drugs, risperidone and aripiprazole, are currently approved for the treatment of these conditions in Journal of American Medical Association (subscription)

Onglyza Approved for Treatment of Type 2 Diabetes  -  ‎Aug 10, 2009‎
Their top 3 selling products include PLAVIX® (clopidogrel bisulfate), ABILIFY® (aripiprazole), and AVAPRO®/AVALIDE® (irbesartan and MediNEWS.Direct!

Psychiatric Aspects of HIV Spectrum Disease  -  ‎Aug 28, 2009‎
Thus, the atypical antipsychotic agents less likely to be associated with the metabolic syndrome, ziprasidone and aripiprazole, might be considered the Focus (subscription)

美 ì?¸í„°ë„· '중요 마케팅 통로로 ë¶€ìƒ?'  -  ‎Aug 6, 2009‎
...아울러, 안과ì—?ì„  ì†?눈ì?¹ 발모제 'ë?¼í‹°ì„¸'(Latisse, bimatoprost), ì •ì‹ ê³¼ì—?ì„  '아빌리파ì?´'(Abilify, aripiprazole), 류마티스 전문ì?˜ëŠ” '엔브ë ?'(Enbrel, 디지틀보사

å…¨ç?ƒåŒ»è?¯å¸‚场:å?‘下的曲线 ç–²æ€?下å¥?å“?强音  -  ‎Aug 26, 2009‎
...这些产å“?分别是百时美施贵å®?çš„Abilify(aripiprazole);武田的Actos(pioglitzone);安进的Epogen (epoetin alfa);Forest Laboratoriesçš„Lexapro(escitalopram) 中国生物技术信息网

Buy cheap Abilify Information , side effects, online pills  -  ‎Jun 30, 2009‎
Before you take aripiprazole, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain На плувка и дъно

FDA Advisors Back Additional Antipsychotics for Use in Teens  -  ‎Jul 3, 2009‎
Two other second-generation antipsychotics (SGAs), risperidone and aripiprazole, have previously been approved for treating schizophrenia in patients aged Psychiatric News

Il primo quotidiano e social network di Psichiatria  -  ‎Jul 3, 2009‎
Lo studio CHAT (acronimo di Clozapine Haloperidol Aripiprazole Trial) è una sperimentazione randomizzata che recluterà i pazienti con diagnosi di Associazione Italiana Psichiatri

Treatment of Delusional Parasitosis With Aripiprazole  -  20 Apr 2009
We report 2 cases that responded rapidly to the new antipsychotic agent aripiprazole. A 42-year-old woman with systemic lupus erythematosus reported a Archives of Dermatology

Cops search for clues in slaying  -  ‎Apr 14, 2009‎
Aripiprazole is an antipsychotic medication used to treat schizophrenia, bipolar disorder and other conditions. Police also seized a letter apparently San Diego Union Tribune

Stocks Likely To Give Back Some Ground In Early Trading - US ...  -  ‎Apr 6, 2009‎
...or aripiprazole, from the currently scheduled end date of November 2012 until the expected loss of exclusivity in April 2015. As per the company, RTT News

Bristol-Myers Squibb Announces Extension Of US Agreement For ...  -  ‎Apr 7, 2009‎
...commercialization of ABILIFY®(aripiprazole) from the currently scheduled end date of November 2012 until the expected loss of exclusivity in April 2015. Medical News Today (press release)

Maintenance of Response with Atypical Antipsychotics in the ...  -  ‎Apr 1, 2009‎
Olanzapine did not significantly differ from aripiprazole. The proportion of patients who lost response was significantly lower for olanzapine versus 7thSpace Interactive (press release)

Abilify versus a placebo: Are there any benefits?  -  ‎Apr 13, 2009‎
Critics complained that Bristol-Myers Squibb's researchers set a low bar for "remission" and that their study design gave aripiprazole (Abilify) every Los Angeles Times

Haloperidol changes mRNA expression of a QKI splice variant in ...  -  ‎Mar 31, 2009‎
...(HOG) cell lines were treated with five different antipsychotic drugs including Haloperidol, Aripiprazole, Clozapine, Olanzapine and Risperidone. 7thSpace Interactive (press release)

Amisulpride-Induced Tardive Dyskinesia and Possible Association of ...  -  ‎Apr 9, 2009‎
He was stabilized on olanzapine, up to 20 mg/day for 2 years, and was later switched to aripiprazole due to significant weight gain. Journal of Neuropsychiatry (subscription)

Cost-effectiveness model comparing olanzapine and other oral ...  -  ‎Apr 8, 2009‎
...ziprasidone, and aripiprazole in the treatment of patients with schizophrenia from the perspective of third-party payers in the US health care system. 7thSpace Interactive (press release)

Schizophrenia - Novel Treatment May Provide Relief  -  ‎Apr 1, 2009‎
...take pregnenolone or placebo for eight weeks in conjunction with a newer antipsychotic medication (aripiprazole, olanzapine, quetiapine or risperidone). HealthNewsDigest.com

BRIEFING - ASIA HEALTH - APRIL 13, 2009  -  ‎Apr 12, 2009‎
TOKYO - Otsuka Pharmaceutical Co. said Monday that it has extended its contract with US drugmaker Bristol-Myers Squibb Co. for the aripiprazole Trading Markets (press release)

Company and People Notes: BMS and Otsuka Extend Abilify Agreement ...  -  ‎Apr 9, 2009‎
...of Abilify (aripiprazole) from the currently scheduled end date of November 2012 until the expected loss of the drug's exclusivity in April 2015. Pharmaceutical Technology Magazine

COMUNICADO: Long-Term Tolerability and Safety Data of ABILIFY(R ...  -  ‎Apr 3, 2009‎
ABILIFY(R) (aripiprazole), when used in combination with lithium or valproate, is a generally well-tolerated long-term treatment for patients with Bipolar I Europa Press (Comunicado de prensa)

Heavy metal detox  -  ‎Mar 31, 2009‎
...aripiprazole, clozapine, olanzapine, quetiapine, risperidone, sertindole, ziprasidone, and zotep-ine) against the earlier generation of these drugs. What Doctors Don't Tell You

Bristol-Myers : nouvel accord avec Otsuka sur Abilify.  -  ‎Apr 6, 2009‎
...un accord avec le japonais Otsuka Pharmaceutical concernant leur coopération au sujet du médicament contre la schizophrénie Abilify (aripiprazole). Boursorama

Ð’ 100 медпрепаратах – перебор Ñ? побочными Ñ?ффектами  -  ‎Apr 2, 2009‎
Препарат от шизофрении «Abilify» (aripiprazole) (американÑ?каÑ? компаниÑ? Bristol Myers Squibb Co) имеет выÑ?окое токÑ?ичное воздейÑ?твие на печень, Вечерний Харьков

大塚製薬ã€?米ブリストルマイヤーズ・スクイブ社ã?¨æŠ—精神病薬 ...  -  ‎Apr 6, 2009‎
...ï¼£ï½?rnelius)ã?¨ã€?抗精神病薬「ABILIFY(R)ã€?(日本語表記:エビリファイã€?一般å??:アリピプラゾールï¼?ï½?riï½?iï½?ï½’ï½?zï½?le)ã?®ç±³å›½ã?«ã?Šã?‘ã‚‹ 日本経済新聞 (プレスリリース)

Aripiprazole Boosts Efficacy of Antidepressants in Older Patients ...  -  ‎Mar 7, 2009‎
By Emma Hitt, PhD HONOLULU -- March 7, 2009 -- Adjunctive aripiprazole appears to be effective in relieving the symptoms of depression in patients aged 50 DG News

Changing Rx Practices in the Treatment of Mental Illness: Impact ...  -  ‎Mar 12, 2009‎
...(2003a, 2003b) have demonstrated the effectiveness of the atypical antipsychotic drugs Aripiprazole and Ziprasidone in the double-blind, placebo-controlled Forensic Examiner

Dangerous medicines in drugstores  -  ‎Mar 10, 2009‎
In particular, it contains medicine for schizophrenia Abilify (aripiprazole) made by US company Bristol Myers Squibb Co. It has a high toxic effect on liver MIGnews.com.ua

Redefining Antipsychotics  -  ‎Mar 9, 2009‎
In order of approval, these are risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole, and paliperidone. Although the degree to which this group of Medscape

Data Demonstrates Metabolic Benefits of Adding CORLUX(R) to ...  -  ‎Feb 23, 2009‎
These medications are: Abilify® (aripiprazole, Bristol Myers Squibb and Otsuka American Pharmaceutical) Clozaril® (clozapine, Novartis) Geodon® (ziprasidone CNNMoney.com

Mortality With Antipsychotic Use in Alzheimer Disease  -  ‎Mar 4, 2009‎
...risk of stroke with 3 second-generation antipsychotics based on a meta-analysis of 11 trials with risperidone or olanzapine and 3 with aripiprazole. Psychiatric Times

Ask the Expert: Geriatric Psychiatry  -  ‎Feb 25, 2009‎
...the FDA conducted an extensive meta-analysis of the 17 placebo-controlled North American and European trials of risperidone, quetiapine, aripiprazole, Focus (subscription)

Families of the Wounded Fund to benefifrom auction and gala this ...  -  ‎Feb 25, 2009‎
...age 35 and currently taking one of five medications for schizophrenia, including olanzaphine, risperidone/paliperidone, quetiapine or aripiprazole. Chesterfield Observer (subscription)

Feketelistás gyógyszerek  -  ‎Mar 12, 2009‎
A felsorolásban szerepel többek között az amerikai gyártmányú Ability (aripiprazole), melyet a skizofrénia kezelésére alkalmaznak. Kárpáti Igaz Szó

Минздрав готовит "черный" Ñ?пиÑ?ок медицинÑ?ких препаратов  -  ‎Mar 12, 2009‎
в том чиÑ?ле и в Украине. Это, в чаÑ?тноÑ?ти, препарат от шизофрении Abilify (aripiprazole) производÑ?тва американÑ?кой компании Bristol Myers Squibb Co. Версии.сом

Минздрав Ñ?оÑ?тавлÑ?ет "черный" Ñ?пиÑ?ок лекарÑ?тв  -  ‎Mar 9, 2009‎
Ð’ чаÑ?тноÑ?ти, отмечает издание, в Ñ?пиÑ?ок входит препарат длÑ? лечениÑ? шизофрении "Abilify" (aripiprazole) производÑ?тва американÑ?кой компании "Bristol Myers ЛІГА.Новости

Brand Names/Synonyms:
Aripiprazole is also known by the following brand names and/or synonyms:
Abilify; Abilitat; Aripiprazole; Aripiprazole [Usan]; OPC 31

Drug Category:
Aripiprazole is categorized under the following by the FDA: Antipsychotics; ATC:N05AX12

Dosage Forms:
Not Available

Absorption:
Not Available

Interactions:
[an error occurred while processing this directive]



Chemical IUPAC Name:
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one





Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy