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AvalideThis page contains recent news articles, when available, and an overview of Avalide but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Avalide (when available) Irbesartan, an angiotensin II receptor antagonist similar to losartan and valsartan, is used alone or with hydrochlorothiazide to treat hypertension For the treatment of hypertension. Mechanism Of Action: Irbesartan antagonizes angiotensin II, the primary vasoactive hormone of the renin-angiotensin system, at the AT1 receptor subtype. As angiotensin II is vasoconstrictor which stimulates aldosterone secretion by the adrenal gland, blockage of its effects results in a decrease in systemic vascular resistance. News Articles on Irbesartan Bristol-Myers Squibb Achieves Strong Sales, Earnings Performance in Third Quarter - Oct 22, 2009 2008 Three Months Ended September 30, BioPharmaceuticals Cardiovascular Plavix $ 1554 $ 1439 8 % $ 1406 $ 1263 11 % 4 % Avapro/Avalide 329 334 (1 )% 186 189 ... Reuters Brand Names/Synonyms: Avalide is also known by the following brand names and/or synonymsAvalide; Avapro; CHEMBANK1635; Irbesarran; Irbesartan; Irbesartan [Usan:Inn]; Lrbesartan Drug Category: Avalide is categorized under the following by the FDA: Antihypertensive Agents; Angiotensin II Receptor Antagonists; ATC:C09CA04 Dosage Forms: Oral tablets Absorption: 60-80% Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: 3-butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one |
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