Avodart

This page contains recent news articles, when available, and an overview of Avodart but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Avodart
(when available)

Pharmacology and use:
Dutasteride is a synthetic 4-azasteroid compound that is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5 alpha-reductase (5AR), an intracellular enzyme that converts testosterone to 5 alpha-dihydrotestosterone (DHT). Dutasteride is indicated for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland. For the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland

Mechanism Of Action:
Dutasteride inhibits the conversion of testosterone to 5 alpha-dihydrotestosterone (DHT). DHT is the androgen primarily responsible for the initial development and subsequent enlargement of the prostate gland. Testosterone is converted to DHT by the enzyme 5 alpha-reductase, which exists as 2 isoforms, type 1 and type 2. The type 2 isoenzyme is primarily active in the reproductive tissues while the type 1 isoenzyme is also responsible for testosterone conversion in the skin and liver. Dutasteride is a competitive and specific inhibitor of both type 1 and type 2 5 alpha-reductase isoenzymes, with which it forms a stable enzyme complex. Dissociation from this complex has been evaluated under in vitro and in vivo conditions and is extremely slow. Dutasteride does not bind to the human androgen receptor.

News Articles on Dutasteride

Preventing prostate problems  -  ‎Dec 27, 2009‎
Finasteride (Proscar, generic) and dutasteride (Avodart) may have a role in prevention for select men with particular needs, but nothing in your history ... Chicago Daily Herald

Research Oracle roundup for 17 December 2009  -  ‎Dec 17, 2009‎
The predominance of late stage products such as Horizon (COPD), Avodart (prostate cancer), MenHibrix (Meningitis, US), Arzerra (cancer) and Benlysta (lupus) ... Research Oracle (blog)

Questions Unasked about Cancer Prevention  -  ‎Nov 13, 2009‎
How many men take finasteride (generic Propecia, $2 a day) or dutasteride (GlaxoSmithKline's Avodart, $3.50 a day) to prevent prostate cancer compared to ... GoozNew (blog)

Lake Hollingworth Restrooms  -  ‎Nov 11, 2009‎
As for the need for restrooms, does Mr. Culberson think that all male baby boomers take Avodart. What can women joggers do - Depends! ... The Ledger

GlaxoSmithKline Sees 30-40 Pdt Launches In Japan In 4 Yrs-CEO  -  ‎Oct 28, 2009‎
It recently launched prostate treatment Avodart as Avolve in Japan, and received approval to sell its cervical cancer vaccine Cervarix there. ... Wall Street Journal

ProtoxPresents Data, Awaits Key Results for PRX302  -  ‎Nov 8, 2009‎
...sales for BPH drugs (eg Flomax, Avodart, Proscar) and the 575000 surgical procedures that are performed each year in the top seven markets worldwide. ... OneMedPlace (blog)

Review: Curb Your Enthusiasm - The Bare Midriff  -  ‎Oct 26, 2009‎
Avodart? That's the weak pee stream pill, right? Or is it Flomax? Whatever it is, I wonder how they feel about their pill being used as a set-up for Jesus' ... TV Squad (blog)

Prostate Health  -  ‎Oct 29, 2009‎
There are a variety of treatments available for men with BPH, including medication (alpha-blockers, and hormonal agents such as Proscar and Avodart, ... Men's News Daily

BREAKING NEWS: Relenza helps GSK return to sales growth  -  ‎Oct 28, 2009‎
Other strong performances came from Avodart (dutasteride), for the treatment of benign prostatic hyperplasia (+14% to £131 million), the heart disease drug ... Pharma Times

GSK lanza medicamento reduce tamaño de próstata y alivia síntomas de ...  -  ‎Nov 10, 2009‎
La compañía farmacéutica GlaxoSmithKline (GSK) ha puesto a disposición de la comunidad médica el medicamento Avodart que inhibe tanto el tipo 1 como el tipo ... El Nuevo Diario (República Dominicana)

전립선암 치료제 시장 '확대ì?¼ë¡œ'  -  ‎Nov 11, 2009‎
...아울러, 제품수명주기 관리ì?˜ ì?¼í™˜ìœ¼ë¡œ '아보다트'(Avodart, dutasteride), '아바스틴'(Avastin, bevacizumab), '글리벡'(Glivec, imatinib), 수í…?(Sutent, ... 디지틀보사

GlaxoSmithKline will in Japan 30 bis 40 neue Produkte einführen  -  ‎Oct 28, 2009‎
Zuletzt hatte das Unternehmen dort das Prostatamittel "Avodart" unter dem Namen "Avolve" auf den Markt gebracht und die Zulassung für den Verkauf von ... manager-magazin.de

Brand Names/Synonyms:
Avodart is also known by the following brand names and/or synonymsAvodart; Dutasteride; Dutasteride [Usan]; GG 745

Drug Category:
Avodart is categorized under the following by the FDA: Anti-baldness Agents; Antihyperplasia Agents; Unclassified Therapeutic Agents (92:00.00); ATC:G04CB02

Dosage Forms:
CAPSULE

Absorption:
60%

Interactions:
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Chemical IUPAC Name:
Not Available





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