Azulfidine

This page contains recent news articles, when available, and an overview of Azulfidine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Azulfidine (when available)

Pharmacology and use:
Sulfasalazine is an anti-inflammatory indicated for the treatment of ulcerative colitis and rheumatoid arthritis. For the treatment of Crohn's Disease and Rheumatoid Arthritis as a second-line agent

Mechanism Of Action:
The mode of action of Sulfasalazine or its metabolites, 5-aminosalicylic acid (5-ASA) and sulfapyridine (SP), is still under investigation, but may be related to the anti-inflammatory and/or immunomodulatory properties that have been observed in animal and in vitro models, to its affinity for connective tissue, and/or to the relatively high concentration it reaches in serous fluids, the liver and intestinal walls, as demonstrated in autoradiographic studies in animals. In ulcerative colitis, clinical studies utilizing rectal administration of Sulfasalazine, SP and 5-ASA have indicated that the major therapeutic action may reside in the 5-ASA moiety. The relative contribution of the parent drug and the major metabolites in rheumatoid arthritis is unknown.

News Articles on Sulfasalazine

Brand Names/Synonyms:
Azulfidine is also known by the following brand names and/or synonymsAccucol; Alti-Sulfasalazine; Asulfidine; Azlufidine En-Tabs; Azopyrin; Azopyrine; Azulfidine; Azulfidine En-Tabs; Benzosulfa; Colo-Pleon; Pms-Sulfasalazine; Pms-Sulfasalazine E.C.; Reupirin; Rorasul; S.A.S. 500; S.A.S. Enteric-500; S.A.S.-500; Salazopiridazin; Salazopyridin; Salazopyrin; Salazopyrin En-Tabs; Salazosulfapyridin; Salazosulfapyridine; Salicylazosulfapyridine; Salisulf; Sulcolon; Sulfasalazin; Sulfasalazine; Sulphasalazine; W-T Sasp Oral

Drug Category:
Azulfidine is categorized under the following by the FDA: Antirheumatic Agents; Gastrointestinal Agents; Anti-inflammatory Agents; Anti-Infectives; Sulfonamides; ATC:A07EC01

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
2-hydroxy-5-[4-(pyridin-2-ylsulfamoyl)phenyl]azo-benzoicacid

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