Bactroban

This page contains recent news articles, when available, and an overview of Bactroban but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Bactroban
(when available)

Pharmacology and use:
Mupirocin, an antibiotic produced from Pseudomonas fluorescens, is structurally unrelated to any other topical or systemic antibiotics. Mupirocin is used to treat infection caused by Staphylococcus aureus and beta-hemolytic streptococci including Streptococcus pyogenes. This antibiotic has little, if any, potential for cross-resistance with other antibiotics. For the treatment of staphylococci nasal carriers

Mechanism Of Action:
Mupirocin reversibly binds to bacterial isoleucyl-tRNA synthetase, an enzyme which promotes the conversion of isoleucine and tRNA to isoleucyl-tRNA, resulting in the inhibition of bacterial protein and RNA synthesis.

News Articles on Mupirocin

High blood pressure puts expectant mom at risk  -  ‎Dec 24, 2009‎
Bactroban ointment or cream works well. Altabax (retapamulin) ointment is another, newer preparation that does a good job. If the infection has spread, ... SouthCoastToday.com

Brand Names/Synonyms:
Bactroban is also known by the following brand names and/or synonymsBactoderm; Bactroban; Bactroban Nasal; Centany; MRC; Mupirocin; Mupirocine; PSEUDOMONIC ACID; Turixin

Drug Category:
Bactroban is categorized under the following by the FDA: Anti-bacterial Agents; Antibiotics; ATC:D06AX09; ATC:R01AX06

Dosage Forms:
Topical ointment, nasal spray

Absorption:
no measurable systemic absorption

Interactions:
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Chemical IUPAC Name:
13-[3,4-dihydroxy-5-[[3-(2-hydroxy-1-methyl-propyl)oxiran-2-yl]methyl]tetrahydropyran-2-yl]-12-methyl-10-oxo-tridec-11-enoicacid





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