|
 |
Balsalazide disodiumThis page contains recent news articles, when available, and an overview of Balsalazide disodium but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Balsalazide disodium (when available) Balsalazide is a prodrug that is enzymatically cleaved in the colon to produce mesalamine (5-aminosalicylic acid), an anti inflammatory drug indicated for the treatment of mildly to moderately active ulcerative colitis. Balsalazide disodium is delivered intact to the colon where it is cleaved by bacterial azoreduction to release equimolar quantities of mesalamine, which is the therapeutically active portion of the molecule, and 4-aminobenzoyl-(beta)-alanine. For the treatment of mildly to moderately active ulcerative colitis Mechanism Of Action: The mechanism of action of 5-aminosalicylic acid is unknown, but appears to be topical rather than systemic. Mucosal production of arachidonic acid metabolites, both through the cyclooxygenase pathways, i.e., prostanoids, and through the lipoxygenase pathways, i.e., leukotrienes and hydroxyeicosatetraenoic acids, is increased in patients with chronic inflammatory bowel disease, and it is possible that 5-aminosalicylic acid diminishes inflammation by blocking production of arachidonic acid metabolites in the colon. News Articles on Balsalazide Shire Presents Results of Five Lialda(R) (mesalamine) Analyses at ACG 2009 ... - Oct 26, 2009 6 percent of balsalazide [combined results from generic balsalazide disodium and Colazal] patients (n=4557), and 6 percent (500mg) of Dipentum patients ... Reuters Salix Pharmaceuticals, Ltd. - Pharmaceuticals & Healthcare - Deals and ... - Nov 13, 2009 Oral Suspension DIURIL (Chlorothiazide); APRISO (mesalamine) extended-release capsules 0.375 grams, and COLAZAL (balsalazide disodium) Capsules 750 ... PR-inside.com (press release) Brand Names/Synonyms: Balsalazide disodium is also known by the following brand names and/or synonymsBALSALAZIDE; Balsalazida [Spanish]; Balsalazide Disodium; Balsalazido [Spanish]; Balsalazidum [Latin]; Carbadox; Colazal Drug Category: Balsalazide disodium is categorized under the following by the FDA: Anti-ulcer Agents; ATC:A07EC04 Dosage Forms: Not Available Absorption: Not Available Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: 5-[4-(2-carboxyethylcarbamoyl)phenyl]azo-2-hydroxy-benzoicacid |
|
Health Home | Conditions | Cancer | Medications | Surgery | Vaccines The Cancer News Network
COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy |