Beclomethasone

This page contains recent news articles, when available, and an overview of Beclomethasone but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Beclomethasone
(when available)

Pharmacology and use:
Beclomethasone, a synthetic halogenated glucocorticoid with antiinflammatory and vasoconstrictive effects, is used for treating steroid-dependent asthma, allergic or nonallergic rhinitis, or recurrent nasal polyps. For the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older

Mechanism Of Action:
Unbound corticosteroids cross cell membranes and bind with high affinity to specific cytoplasmic receptors. The result includes inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.

News Articles on Beclomethasone

Soligenix Announces Publication of Positive Pre-Clinical Results with RiVax(TM ...  -  ‎Dec 28, 2009‎
Soligenix's lead product, orBec(®) (oral beclomethasone dipropionate or BDP), is a potent, locally acting corticosteroid being developed for the treatment ... PR Newswire (press release)

Best Evidence Review: Long-acting Beta-Agonists -- Are They Appropriate for ...  -  ‎Dec 30, 2009‎
Linear growth in prepubertal asthmatic children treated with montelukast, beclomethasone, or placebo: a 56-week randomized double-blind study. ... Medscape

Soligenix initiates Phase I/II trial for acute radiation enteritis drug  -  ‎Dec 24, 2009‎
...a late-stage biotechnology company, has initiated a Phase I/II clinical trial evaluating SGX201, a time-release formulation of oral beclomethasone 17, ... Trading Markets (press release)

Soligenix Announces Initiation of a Phase 1/2 Clinical Trial of SGX201 for the ...  -  ‎Dec 21, 2009‎
Soligenix's lead product, orBec® (oral beclomethasone dipropionate or BDP), is a potent, locally acting corticosteroid being developed for the treatment of ... CNNMoney.com (press release)

High-dose inhaled steroids for asthma may increase risk of fetal malformations  -  ‎Dec 19, 2009‎
...per day ICS (beclomethasone dipropionate-chlorofluorocarbone equivalent) versus 154 who took >1000 micrograms per day and 8734 who did not take ICS. ... news Stories

'í?´ë¦¬í?¼ì§€ì†?성장용정' 약제 급여기준 신설  -  ‎Dec 21, 2009‎
Beclomethasone dipropionate 경구제(품명: í?´ë¦¬í?¼ì§€ì†?성 장용정 5mg)ì?˜ 급여기준ì?´ 신설ë?œë‹¤. 보건복지가족부는 ì?´ê°™ì?€ ë‚´ìš©ì?„ í?¬í•¨í•œ 약제급여 기준 개정안ì?„ 고시 ... 데일리팜

Soligenix Reports Third Quarter 2009 Financial Results  -  ‎Nov 13, 2009‎
The granting of Orphan Drug Designation by the FDA's Office of Orphan Products Development for oral BDP (beclomethasone 17,21-dipropionate, or orBec®) for ... PR Newswire (press release)

Mometasone Furoate Triumphs Over Beclomethasone Dipropionate in Patients With ...  -  ‎Nov 10, 2009‎
..."When compared to beclomethasone dipropionate aerosol inhaler with hydrofluoroalkane propellant patients, mometasone furoate dry powder inhaler patients ... DG News

Enzon Offloads Specialty Arm to Sigma-Tau for up to $327M  -  ‎Nov 9, 2009‎
Currently, Sigma-Tau's orBec (oral beclomethasone dipropionate) is in Phase III testing for acute graft-vs.-host disease under a partnership with Solgenix ... BioWorld Online

Bullish Technical Breakout Alert (OTC:SNGX.OB)  -  ‎Nov 11, 2009‎
Soligenix's lead product, orBec® (oral beclomethasone dipropionate or BDP), is a potent, locally acting corticosteroid being developed for the treatment of ... OfficialWire (press release)

Teva Pharmaceutical Industries Limited Q3 2009 Earnings Call Transcript  -  ‎Nov 3, 2009‎
The market share in NRx of 17% up from 13% in 2008 and I'm pleased to report that in October, we began Phase III trial of nasal beclomethasone dipropionate ... Seeking Alpha (blog)

Asthma Control Maintained in Children Switched to Once-Daily Mometasone ...  -  ‎Oct 22, 2009‎
...safely controls asthma in children switched from other corticosteroid therapies, such as fluticasone propionate or beclomethasone dipropionate, ... DG News

Soligenix to Present at 8th Annual BIO Investor Forum  -  ‎Oct 27, 2009‎
Soligenix's lead product, orBec® (oral beclomethasone dipropionate or BDP), is a potent, locally acting corticosteroid being developed for the treatment of ... SunHerald.com (press release)

Brand Names/Synonyms:
Beclomethasone is also known by the following brand names and/or synonymsAerobec; Aldecin; Anceron; Andion; Beclacin; Becloforte; Beclomet; Beclometasona [Inn-Spanish]; Beclometasondipropionat Mikron; Beclometasondipropionat Mikron.; Beclometasone; Beclometasonum [Inn-Latin]; Beclomethasone; Beclorhinol; Becloval; Beclovent; Becodisks; Beconase; Beconase Aq; Beconasol; Becotide; Clenil-A; Entyderma; Inalone; Korbutone; Propaderm; Qvar; Qvar 80; Rino-Clenil; Sanasthmax; Sanasthmyl; Vancenase; Vancenase Aq; Vanceril; Vanceril Double Strength; Viarex; Viarox

Drug Category:
Beclomethasone is categorized under the following by the FDA: Antiarrhythmic Agents; Glucocorticoids; Anti-inflammatory Agents; Corticosteroids; ATC:A07EA07; ATC:D07AC15; ATC:R01AD01; ATC:R03BA01

Dosage Forms:
Oral inhalation; Nasal inhalation; Nasal Spray

Absorption:
mean peak plasma concentration was 88pg/ml at 0.5 hour

Interactions:
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Chemical IUPAC Name:
[9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate





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