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BicNUThis page contains recent news articles, when available, and an overview of BicNU but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: BicNU (when available) Carmustine is one of the nitrosoureas indicated as palliative therapy as a single agent or in established combination therapy with other approved chemotherapeutic agents in treatment of brain tumors, multiple myeloma, Hodgkin's disease, and non-Hodgkin's lymphomas. Although it is generally agreed that Carmustine alkylates DNA and RNA, it is not cross resistant with other alkylators. As with other nitrosoureas, it may also inhibit several key enzymatic processes by carbamoylation of amino acids in proteins. For the treatment of brain tumors, multiple myeloma, Hodgkin's disease and Non-Hodgkin's lymphomas. Mechanism Of Action: Carmustine causes cross-links in DNA and RNA, leading to the inhibition of DNA synthesis, RNA production and RNA translation (protein synthesis). Carmustine also binds to and modifies (carbamoylates) glutathione reductase. This leads to cell death. News Articles on Carmustine Brain Tumor - Children Chemotherapy - Brain Tumor - Children Health … - Jun 10, 2008 Carmustine (BCNU, BiCNU). Carmustine is used to treat many types of brain tumors, including glioblastoma, medulloblastoma, and astrocytoma. ... New York Times High-dose chemotherapy using BEAM without autologous rescue … - Oct 2, 2006 ...the treatment regimen consisted of HDC with BEAM (etoposide 200 mg/m 2 twice daily intravenously (iv) for 4 consecutive days (total eight doses), BICNU ... Nature.com Risk factors for invasive aspergillosis in neutropenic patients with ... - Feb 24, 2005 ...stem cell transplantation were mitoxantrone/melphalan (mitoxantrone 60 mg/m 2 iv on day 1 and melphalan 180 mg/m 2 on day 4) or BEAM (BiCNU 300 mg/m 2 ... Nature.com Rifampin, Isoniazid, and Pyrazinamide (Systemic). - Aug 1, 2006 Tegretol) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Dantrolene (eg, Dantrium) or Daunorubicin (eg, Cerubidine) or Divalproex (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com … Testosterone Antianemic Fluoxymesterone Testosterone Antineoplastic... - Oct 27, 2005 Tegretol) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Dantrolene (eg, Dantrium) or Daunorubicin (eg, Cerubidine) or Disulfiram (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Androgens (Systemic).(Drug overview) - May 1, 2006 Tegretol) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Dantrolene (eg, Dantrium) or Daunorubicin (eg, Cerubidine) or Disulfiram (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Estrogens (Systemic). - Jul 28, 2005 Tegretol) or Carmustine (e.g., BiCNU) or Chloroquine (e.g., Aralen) or Dantrolene (e.g., Dantrium) or Daunorubicin (e.g., Cerubidine) or Disulfiram ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Epirubicin (Systemic ).(Drug overview) - May 1, 2006 ...oxandrolone [eg, Oxandrin], oxymetholone [eg, Anadrol], stanozolol [eg, Winstrol]) or Androgens (male hormones) or Carmustine (eg, BiCNU) or Chloroquine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com … Streptomycin Antibacterial, systemic Amikacin Gentamicin Kanamycin... - Jul 28, 2005 Capastat) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Cisplatin (eg, Platinol) or Combination pain medicine containing acetaminophen and ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Antifungals, Azole (Systemic).(Drug overview) - May 1, 2006 ...stanozolol [eg, Winstrol]) or Androgens (male hormones) or Antithyroid agents (medicine for overactive thyroid) or Carmustine (eg, BiCNU) or Chloroquine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Erythromycin and Sulfisoxazole (Systemic). - Oct 27, 2005 Tegretol) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Dantrolene (eg, Dantrium) or Daunorubicin (eg, Cerubidine) or Disulfiram (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Isoniazid (Systemic). - Oct 27, 2005 ...stanozolol [eg, Winstrol]) or Androgens (male hormones) or Antithyroid agents (medicine for overactive thyroid) or Carmustine (eg, BiCNU) or Chloroquine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Anabolic Steroids (Systemic). - Feb 1, 2006 Tegretol) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Dantrolene (eg, Dantrium) or Daunorubicin (eg, Cerubidine) or Disulfiram (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Penicillins (Systemic). - Feb 1, 2006 Winstrol]) or Androgens (male hormones) or Antithyroid agents (medicine for overactive thyroid) or Carmustine (e.g., BiCNU) or Chloroquine (e.g., ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Generic name product may also be available in the US - Jul 28, 2005 Tegretol) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Dantrolene (eg, Dantrium) or Daunorubicin (eg, Cerubidine) or Disulfiram (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Fenofibrate (Systemic).(Drug overview) - Aug 1, 2006 Carmustine (eg, BiCNU) or Cisplatin (eg, Platinol) or Combination pain medicine containing acetaminophen and aspirin (eg, Excedrin) or other salicylates or ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Estrogens and Progestins Oral Contraceptives (Systemic ). - Oct 27, 2005 Tegretol) or Carmustine (eg, BiCNU) or Dantrolene (eg, Dantrium) or Daunorubicin (eg, Cerubidine) or Disulfiram (eg, Antabuse) or Divalproex (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Rifampin, Isoniazid, and Pyrazinamide (Systemic).(Drug overview) - May 1, 2006 Tegretol) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Dantrolene (eg, Dantrium) or Daunorubicin (eg, Cerubidine) or Divalproex (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Fenofibrate (Systemic).(Drug overview) - May 1, 2006 Carmustine (eg, BiCNU) or Cisplatin (eg, Platinol) or Combination pain medicine containing acetaminophen and aspirin (eg, Excedrin) or other salicylates or ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Comfrey. - May 1, 2006 Medicines used to treat some types of cancer (Carmustine (BiCNU(R)); Mercaptopurine (Purinethol(R))) * Medicine used to replace male hormones ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com Conjugated Estrogens and Medroxyprogesterone For Ovarian Hormone … - Feb 1, 2006 ...agents (medicine for overactive thyroid) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Dantrolene (eg, Dantrium) or Daunorubicin (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Erythromycin and Sulfisoxazole (Systemic).(Drug overview) - May 1, 2006 Tegretol) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Dantrolene (eg, Dantrium) or Daunorubicin (eg, Cerubidine) or Disulfiram (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Antiadrenal Ketoconazole Antifungal, systemic Fluconazole Itraconazole... - Aug 1, 2006 ...stanozolol [eg, Winstrol]) or Androgens (male hormones) or Antithyroid agents (medicine for overactive thyroid) or Carmustine (eg, BiCNU) or Chloroquine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Aminoglycosides (Systemic).(Drug overview) - May 1, 2006 Capastat) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Cisplatin (eg, Platinol) or Combination pain medicine containing acetaminophen and ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Conjugated Estrogens and Medroxyprogesterone For Ovarian Hormone … - May 1, 2006 ...agents (medicine for overactive thyroid) or Carmustine (eg, BiCNU) or Chloroquine (eg, Aralen) or Dantrolene (eg, Dantrium) or Daunorubicin (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Epirubicin (Systemic ). - Feb 1, 2006 ...oxandrolone [eg, Oxandrin], oxymetholone [eg, Anadrol], stanozolol [eg, Winstrol]) or Androgens (male hormones) or Carmustine (eg, BiCNU) or Chloroquine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Kava. - May 1, 2006 Medicines used to treat cancer or rheumatoid arthritis (examples: Carmustine (BiCNU(R)); Methotrexate (Folex(R), Rheumatrex(R)); ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com Article - Bulletin d'information toxicologique - Centre de toxicologie... - Jun 12, 2006 Que signifient pour vous TMX, HCT, 5-FU, CCNU, BiCNU? (Triméthoprim-sulfaméthoxazole, hydrochlorothiazide, 5-fluoro-uracile, lomustine, carmustine). ... INSPQ Brand Names/Synonyms: BicNU is also known by the following brand names and/or synonymsBCNU; Becenun; Bi Cnu; Bicnu; Bischlorethylnitrosourea; Bischlorethylnitrosurea; Carmubris; Carmustin; Carmustine; FDA 0345; Gliadel; Gliadel Wafer; Nitrumon; SRI 1720 Drug Category: BicNU is categorized under the following by the FDA: Antineoplastic Agents; ATC:L01AD01 Dosage Forms: 100 mg single dose vials of lyophilized material Absorption: 5 to 28% bioavailability Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: N-(2-chloroethyl)-1-(2-chloroethylamino)-N-nitroso-methanamide |
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