Brimonidine tartrate

This page contains recent news articles, when available, and an overview of Brimonidine tartrate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Brimonidine tartrate
(when available)

Pharmacology and use:
Brimonidine significantly lowers intraocular pressure with minimal effects on cardiovascular and pulmonary parameters. It lowers intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow. For the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Mechanism Of Action:
Brimonidine is an alpha adrenergic receptor agonist. It has a peak ocular hypotensive effect occurring at two hours post-dosing. Fluorophotometric studies in animals and humans suggest that Brimonidine has a dual mechanism of action by reducing aqueous humor production and increasing uveoscleral outflow.

News Articles on Brimonidine

Allergan wins brimonidine patent infringement case  -  ‎Nov 4, 2009‎
...purported generic versions of the company's formulations of brimonidine tartrate 0.1% and 0.15% (Alphagan P) for ocular hypertension and glaucoma. ... ModernMedicine

Allergan wins patent infringement suit over generic versions of brimonidine  -  ‎Oct 30, 2009‎
Allergan filed the suit claiming the defendants infringed on the patent for Alphagan (brimonidine tartrate ophthalmic solution 0.1% and 0.15%) when seeking ... OSN SuperSite

Allergan Reports Third Quarter 2009 Operating Results  -  ‎Oct 29, 2009‎
...proposed generic versions of Allergan`s ALPHAGAN P (brimonidine tartrate ophthalmic solution) 0.1% and 0.15% products infringe Allergan`s patents. ... Reuters

Allergan wins brimonidine patent infringement case against Exela PharmSci & Apotex  -  ‎Oct 27, 2009‎
...the 'Defendants') for seeking to market purported generic versions of Allergan's drugs Alphagan P (brimonidine tartrate ophthalmic solution) 0.1% and ... pharmabiz.com

Aerobic exercise and intraocular pressure in normotensive and ...  -  ‎Aug 13, 2009‎
...latanoprost 0.005% (Group C), or brimonidine tartrate 0.2% (Group D) was instilled; and primary glaucoma patients under monotherapy with beta-blockers 7thSpace Interactive (press release)

Experimental and Clinical Evidence for Brimonidine as an Optic ...  -  ‎Apr 13, 2009‎
Objective To review the available evidence for the neuroprotective qualities of brimonidine tartrate in optic nerve and retinal injury. Archives of Ophthalmology

Lotus Pharma Reports Solid 2008 but Still Lacks Cash  -  ‎Apr 17, 2009‎
On the revenue front, Lotus said the increase was derived from increased sales of its own Brimonidine Tartrate Eye Drops and a number of third-party Seeking Alpha

Court Report  -  ‎Apr 12, 2009‎
...of an ANDA to manufacture a generic version of Allergan's Combigan® (brimonidine tartrate/timolol maleate ophthalmic solution, used to treat glaucoma). Patent Docs

Lotus Increases Profit In Q3 While Revenues Drop  -  Nov 18, 2008
Lotus said that strong revenues from its newest drug, Brimonidine Tartrate Eye Drops, a glaucoma treatment, were responsible for much of the rise in istockAnalyst.com (press release),

Lotus Pharmaceuticals Announces Third Quarter 2008 Results  -  Nov 18, 2008
This increase was attributable to strong sales for the Company's Brimonidine Tartrate Eye Drops, used in the treatment of glaucoma, and strong sales of a Earthtimes (press release),

Lotus Pharmaceuticals Announces Third Quarter 2008 Results  -  Nov 18, 2008
This increase was attributable to strong sales for the Company's Brimonidine Tartrate Eye Drops, used in the treatment of glaucoma, and strong sales of a PharmaLive.com (press release),

Lotus Pharmaceuticals Announces Second Quarter 2008 Results  Aug 18, 2008
This increase was because of increased sales of third- party pharmaceuticals and increased sales of the Company's Brimonidine Tartrate Eyes Drops (soldEarthtimes (press release),

Lotus Pharmaceuticals Announces Second Quarter 2008 Results  Aug 18, 2008
This increase was because of increased sales of third- party pharmaceuticals and increased sales of the Company's Brimonidine Tartrate Eyes Drops (soldBiloxi Sun Herald,

Allergan reports 20.1% rise in second-quarter product sales  -  Aug 1, 2008
Alphagan P (brimonidine tartrate 0.15%), Alphagan (brimonidine tartrate) and Combigan (0.2% brimonidine tartrate, 0.5% timolol maleate) sales totaled OSN SuperSite (subscription),

Hyperemia in Glaucoma Patients  -  Jul 25, 2008
Demographic and clinical factors associated with development of brimonidine tartrate 0.2%-induced ocular allergy. J Glaucoma. 2004;13:163-167. Medscape (subscription)

Lotus plant sows seeds for growth  -  Jul 29, 2008
Last year's key earners included the vasodilator valsartan, the glaucoma drug brimonidine tartrate, the antibacterial levofloxacin and nicergoline for In-PharmaTechnologist.com,

Intoxicación por brimonidina en pediatría. Presentación como ...  -  Jul 22, 2008
Twelve-month results of an ongoing randomized trial comparing brimonidine tartrate 0.2 % and timolol 0.5 % given twice daily in patients with glaucoma or Anales de Pediatría,

Brimonidine tartrate can successfully reduce halo size and pupil ...  -  Jun 10, 2008
Ji Hoon Lee, MD, and colleagues evaluated the effect of Alphagan (brimonidine tartrate 0.2%, Allergan) on halo and pupil size after administering the drug OSN SuperSite (subscription),

Learn about the World Ophthalmic Pharmaceutical Drugs Market  -  Jun 27, 2008
1% II-75 Alimera Sciences Unveils Soothe(tm) Emollient Eye Drops II-75 Novartis Introduces Zaditen in Japan II-76 Falcon Releases Brimonidine Tartrate Market Wire (press release)

Allergan reports 23% rise in first-quarter total product net sales  -  May 8, 2008
Alphagan P (brimonidine tartrate 0.15%), Alphagan (brimonidine tartrate) and Combigan (0.2% brimonidine tartrate, 0.5% timolol maleate) sales totaled $99.5 OSN SuperSite (subscription),

Lotus Pharmaceuticals, Inc. Announces First Quarter 2008 Results  -  May 21, 2008
We focused our sales efforts on our top selling products, Brimonidine Tartrate Eyes Drops and VALSARTAN Capsules, and continued to distribute higher-margin, Earthtimes (press release),

Lotus Reports Higher Q1 and New Asthma Drug  -  May 22, 2008
Lotus said that much of that gain was derived from sales of Brimonidine Tartrate Eyes Drops, a drug used to treat glaucoma, and also Valsartan Capsules, istockAnalyst.com,

Brand Names/Synonyms:
Brimonidine tartrate is also known by the following brand names and/or synonyms:
Alphagan; Alphagan P; Brimonidine; Brimonidine Tartrate; Bromoxidine; CHEMBANK1623

Drug Category:
Brimonidine tartrate is categorized under the following by the FDA: Antihypertensive Agents; EENT Drugs; ATC:S01EA05

Dosage Forms:
0.2% solution

Absorption:
Minimal systemic absorption occurs after ocular insertion.

Interactions:
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Chemical IUPAC Name:
5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine





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