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BuclizineThis page contains recent news articles, when available, and an overview of Buclizine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Buclizine (when available) Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects. For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems). Mechanism Of Action: Vomiting (emesis) is essentially a protective mechanism for removing irritant or otherwise harmful substances from the upper GI tract. Emesis or vomiting is controlled by the vomiting centre in the medulla region of the brain, an important part of which is the chemotrigger zone (CTZ). The vomiting centre possesses neurons which are rich in muscarinic cholinergic and histamine containing synapses. These types of neurons are especially involved in transmission from the vestibular apparatus to the vomiting centre. Motion sickness principally involves overstimulation of these pathways due to various sensory stimuli. Hence the action of buclizine which acts to block the histamine receptors in the vomiting centre and thus reduce activity along these pathways. Furthermore since buclizine possesses anti-cholinergic properties as well, the muscarinic receptors are similarly blocked. News Articles on Buclizine Post-concussion syndrome healing process often a lengthy one - Nov 13, 2009 He may benefit from trying an antivertigo/antinausea medication such as buclizine, cyclizine or meclizine. The blurred vision is more difficult. ... Tulsa World Dr. Gott: Post-concussion syndrome explained - Nov 10, 2009 He may benefit from trying an antivertigo/antinausea medication such as buclizine, cyclizine or meclizine. The blurred vision is more difficult. ... Pasadena Star-News Meclizine/Buclizine/Cyclizine (Systemic). - Feb 1, 2006 Buclizine, cyclizine, and meclizine are used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness, and vertigo (dizziness ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Migraine - Healthcare Republic News - Oct 28, 2005 Products containing a painkiller plus an anti-sickness agent (anti-emetic) such as buclizine may help if the headache is accompanied by nausea. ... Healthcare Republic - Healthcare Republic Drugs trial raises hope of migraine cure - Dec 26, 2007 Other treatments include aspirin, paracetamol and stronger pain-killers, such as Migraleve, which contains paracetamol, codeine phosphate and buclizine ... Belfast Telegraph Potassium Supplements (Systemic). - Feb 1, 2006 ...disease or other conditions affecting control of muscles) or Antihistamines or Antipsychotic medicine (medicine for mental illness) or Buclizine (e.g., ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com OTC: Oh my head.(over-the counter)(migraine: diagnosis and treatment) - Feb 5, 2005 Buclizine is included in the OTC medicine Migraleve and is an antihistamine which acts as an antiemetic and a sedative, helping the patient to relax. ... Free with registration - Chemist & Druggist - AccessMyLibrary.com Antifungals, Azole (Systemic).(Drug overview) - May 1, 2006 ...conditions affecting control of muscles) or Antihistamines or Antipsychotics (medicine for mental illness) or Buclizine (eg, Bucladin) or Cyclizine (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Potassium Supplements (Systemic). - May 1, 2006 ...disease or other conditions affecting control of muscles) or Antihistamines or Antipsychotic medicine (medicine for mental illness) or Buclizine (e.g., ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com OTC: Attacking migraine. - Aug 6, 2005 ...such as aspirin, paracetamol and ibuprofen to treat headache pain, on their own or combined with anti-emetics, such as buclizine or prochlorperazine, ... $4.95 - Chemist & Druggist - ECNext Antiadrenal Ketoconazole Antifungal, systemic Fluconazole Itraconazole... - Aug 1, 2006 ...conditions affecting control of muscles) or Antihistamines or Antipsychotics (medicine for mental illness) or Buclizine (eg, Bucladin) or Cyclizine (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com Georgia Code - 16-13-71. (a) A "dangerous drug" means any drug other ... - Aug 4, 2005 ...(113) Brucella antigen; (114) Brucella protein nucleate; (115) Buclizine; (115.3) Budesonide; (115.5) Bumetanide; (116) Bupivacaine; (116.05) Reserved; ... Pay-Per-View - Georgia Code - Loislaw PHARMACY UPDATE: OTC triptans are coming - Dec 17, 2005 Antiemetics such as buclizine hydrochloride and prochlorperazine. * Analgesic/antiemetic combinations. Analgesics should be taken as soon as possible after ... Pay-Per-View - Chemist & Druggist - Factiva, from Dow Jones Product Round-up: First line migraine help. - Mar 13, 2006 ...associated with migraine Pfizer Consumer Health markets Migraleve, containing the anti-emetic buclizine and the analgesics, paracetamol and codeine. ... $9.94 - Community Pharmacy - Alacra Store OTC - MIGRAINE: Migraleve delivers double whammy.(Brief article) - Jul 29, 2006 Sufferers should start with Migraleve Pink, which contains paracetamol and codeine to treat pain, along with buclizine to relieve nausea. ... $4.95 - Chemist & Druggist - ECNext Chemicals, raw materials & specialties.(BROMOCRESOL GREEN, … - Dec 1, 2007 BUCLIZINE HYDROCHLORIDE RONAS CHEMICALS IND. CO., LTD. BUDESONIDE * SPECTRUM CHEMICAL MFG. CORP. [telephone] 800-378-7899, ask for catalog ... $4.95 - Chemical Week - ECNext Pain relief: Help with headaches. - Mar 13, 2006 ...an antihistamine such as diphenhydramine or doxylamine, the vasoconstrictor isometheptene or the anti-emetic buclizine [see table]. ... $4.95 - Community Pharmacy - ECNext * To look at treatments to prevent, shorten or lessen the impact of... - Jul 29, 2006 Buclizine is in the OTC medicine Migraleve and is an antihistamine that acts as an antiemetic and a sedative. If customers feel they aren't getting the best ... $4.95 - Chemist & Druggist - ECNext Brand Names/Synonyms: Buclizine is also known by the following brand names and/or synonymsA 7668; AH 2526; Aphilan R; Aphilan-R Base; Bucladin; Bucladin-S; Buclifen; Buclina; Buclizina [Inn-Spanish]; Buclizine; Buclizine Dihydrochloride; Buclizine Hydrochloride; Buclizine, Hydrochloride; Buclizinum [Inn-Latin]; Buclodin; Histabuticine; Histabutizine; Histabutyzine; Histabutyzine Dihydrochloride; Histabutyzine Hydrochloride; Hitabutyzyne; Longifene; None; Posdel; Postafen; Softran; UCB 4445; UCB-4445; Vibazine; Vibazine Hydrochloride Drug Category: Buclizine is categorized under the following by the FDA: Antiemetics; Antihistamine; Anticholinergic; ATC:R06AE01 Dosage Forms: TABLET (50 mg) Absorption: Rapidly absorbed following oral administration. Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: 1-[(4-chlorophenyl)-phenyl-methyl]-4-[(4-tert-butylphenyl)methyl]piperazine |
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