Bumetanide

This page contains recent news articles, when available, and an overview of Bumetanide but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Bumetanide
(when available)

Pharmacology and use:
Bumetanide, a sulfonamide-type loop diuretic structurally related to furosemide, is used to manage hypertension and edema associated with congestive heart failure, cirrhosis, and renal disease, including the nephrotic syndrome. Bumetanide inhibits sodium reabsorption in the ascending limb of the loop of Henle. For the treatment of edema associated with congestive heart failure, hepatic and renal disease including the nephrotic syndrome

Mechanism Of Action:
Bumetanide interferes with renal cAMP and/or inhibits the sodium-potassium possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule. This results in excretion of sodium, chloride, and water and, hence, leads to diuresis.

News Articles on Bumetanide

Will Economic Adulteration Help Bring Down DSHEA?  -  14 Nov 2009
...which it considered unapproved drugs, noting its laboratory tests have found sibutramine, fenproporex, fluoxetine, bumetanide, furosemide, phenytoin, ... Natural Products Industry Insider

Eagles' Hanson hit with four-game suspension  -  ‎Nov 12, 2009‎
All of those players claimed they took the weight-loss supplement StarCaps, which has diuretic bumetanide. The players argued that the league knew ... Philadelphia Inquirer

Loophole leads Vikes' case to Congress  -  ‎Nov 4, 2009‎
But since these two Minnesota Vikings defensive linemen tested positive for a banned drug -- a diuretic called bumetanide, which they say was in aa legal ... ESPN

Congress will examine Vikings' StarCaps case  -  ‎Oct 28, 2009‎
The league attempted to impose four-game suspensions on the players last year for testing positive for bumetanide, a diuretic that's on the league's list of ... Washington Post

Steroid statism  -  ‎Nov 11, 2009‎
Some background: The NFL's steroid-testing program includes on its banned list a diuretic called bumetanide. The substance is not in itself a steroid, ... The Free Lance-Star

Goodell asks Congress for help on anti-doping  -  ‎Nov 6, 2009‎
The Vikings players tested positive in 2008 for the diuretic bumetanide, which is banned by the NFL because it can mask the presence of steroids. ... WSFA

NFL's Goodell to testify on Vikings suspensions  -  ‎Oct 30, 2009‎
The Vikings players tested positive in 2008 for the diuretic bumetanide, which is banned by the NFL because it can mask the presence of steroids. ... The Associated Press

New Orleans Saints' Will Smith making noise, silencing critics  -  ‎Nov 13, 2009‎
...policy after testing positive for bumetanide, a banned diuretic that was an unlisted ingredient in an over-the-counter weight loss product starcaps. ... NOLA.com

The Eighth Circuit Court of Appeals hasn't been good to the NFL in two recent ...  -  ‎Nov 11, 2009‎
Four defensive linemen who were caught using bumetanide, a masking agent that is used to cover up steroids, are beating the system, using litigation to do ... ESPN

NFL Capsules: Spiraling Niners need boost  -  ‎Nov 12, 2009‎
Two Minnesota Vikings, Kevin Williams and Pat Williams — who are not related — tested positive in 2008 for the diuretic bumetanide, which is banned by the ... Brownsville Herald

Congress continues to sniff around NFL issues  -  ‎Oct 30, 2009‎
...and Kevin Williams after testing positive for Bumetanide, a prescription diuretic that also is a banned substance under the league's steroids policy. ... ProFootballTalk

WSJ Panel Grades Sports Organizations On Drug Testing Policies  -  ‎Nov 12, 2009‎
Vikings DTs Kevin and Pat Williams and Saints DEs Will Smith and Charles Grant were "caught using bumetanide, a masking agent that is used to cover up ... SportsBusiness Daily (subscription)

LWIB: StarCaps & MLB, Poll on Competitive Balance, Credit Facility, World ...  -  ‎Nov 9, 2009‎
A quick summary of the history of “StarCaps�: Two Minnesota Vikings players tested positive last season for the aforementioned “Bumetanide� as a result of ... The Biz of Baseball

Four Pharmaceutical Companies Pay $124 Million for Submission of False Claims ...  -  ‎Oct 19, 2009‎
Ibuprofen tablets, Bumetanide, Cephalexin and Cefactor) and several UDL drugs (nifedipine extended release tablets, selegiline HCL, Triamterene & HCTZ, ... Reuters

US lawmaker fears rulings undermine dope tests  -  ‎Nov 3, 2009‎
The NFL tried to ban the Vikings defenders four games each after they tested positive last year for the banned diuretic bumetanide, a steroid masking agent. ... AFP

Editorial: Congress needs to let NFL devise its own drug policies  -  ‎Nov 10, 2009‎
...which did not state on the label that it contained diuretic bumetanide, and which is banned by the NFL because it can mask the presence of steroids. ... Tri-Valley Herald

Brady Quinn to start for Browns on Monday night  -  ‎Nov 11, 2009‎
Two Minnesota Vikings, Kevin Williams and Pat Williams -- who are not related -- tested positive in 2008 for the diuretic bumetanide, which is banned by the ... The Detroit News

Goodell to testify at StarCaps hearing  -  ‎Oct 31, 2009‎
NFL commissioner Roger Goodell is expected to testify next week at a House subcommittee discussing the league's anti-doping policy. ... 12th Fan.com (subscription)

Williamses reach appeals court  -  ‎Aug 18, 2009‎
He also faulted the league for failing to warn players that bumetanide is contained in StarCaps, even though the league knew that in 2006. Minneapolis Star Tribune

Evans exploiting his opportunities  -  ‎Aug 24, 2009‎
The Williamses were handed four-game suspensions last year after testing positive for the banned substance bumetanide, but they have been appealing those Viking Update (subscription)

Vikings' suspensions case awaits federal ruling  -  ‎Aug 5, 2009‎
The diuretic, bumetanide, wasn't listed on the label. The NFL wants to suspend the players for four games each. "I just want it to be over," Pat Williams The Associated Press

The Michael Vick Chronicles: A Football-Heavy Look at Sports and ...  -  ‎Aug 19, 2009‎
Remember the so-called StarCaps case from last season, when the NFL moved to suspend five players who tested positive for a banned diuretic, bumetanide, The American Lawyer

Deuce 'ready,' waiting for call  -  ‎Aug 17, 2009‎
Star Caps, an over-the-counter weight loss product, do contain a banned diuretic, bumetanide, although it is not listed on the product's label. Jackson Clarion Ledger

NFLPA makes appeal on behalf of Will Smith and Charles Grant of ...  -  ‎Aug 18, 2009‎
He upheld the NFL's four-game suspension of the players, all of whom tested positive last summer for a banned diuretic, bumetanide, in the StarCaps saga. The Times-Picayune - NOLA.com

Offensive-Minded Saints Hoping to Crank Up the 'D'  -  ‎Aug 13, 2009‎
Grant and Smith will miss the first four games of the season due to suspension -- both tested positive for a banned diuretic, bumetanide, last summer. FanHouse

Maclin signs and appears at Eagles camp  -  ‎Aug 5, 2009‎
The Williamses have acknowledged taking StarCaps, which contained an unlisted but illegal ingredient called bumetanide that can mask the presence of Wilkes Barre Times-Leader

[ FDA SAFETY INFORMATION ] FDA Safety Information: Stop Recalls ...  -  ‎Aug 3, 2009‎
For example, in February, the FDA said a product called StarCaps - promoted as an all-natural weight-loss supplement - contained bumetanide, The Ledger

Court Temporarily Halts NFL's Drug Testing Players During Legal ...  -  ‎Aug 4, 2009‎
The two players had tested positive in 2008 for bumetanide, a diuretic banned by the NFL's Policy on Anabolic Steroids and Related Substances because it may Linex Legal (subscription)

NFL to investigate alleged fight between Raiders coaches  -  ‎Aug 18, 2009‎
The diuretic, bumetanide, wasn't listed on the label. The players want some of their arguments in the case heard in state court. SunHerald.com (registration)

NFL Capsules: Appeals court considers NFL suspensions case  -  ‎Aug 18, 2009‎
They had taken the over-the-counter weight loss supplement StarCaps, which did not state on the label that its ingredients included bumetanide, Brownsville Herald

Hartley remorseful over four-game suspension  -  ‎Aug 16, 2009‎
Grant and Smith both tested positive late in 2008 for bumetanide, a chemical that was in a pill known as StarCaps, which they took to lose weight. WWL

MLB, NBA, NHL support NFL's case against Minnesota Vikings' Kevin ...  -  13 Jul 2009
The Williamses are fighting four-game suspensions after testing positive last year for Bumetanide, which the league and NFLPA classify as a masking agent Pioneer Press

Mayfield, NFL's Williamses take doping cases to court  -  ‎Jul 9, 2009‎
The players argued that they unknowingly ingested the diuretic bumetanide when they took the weight-loss supplement StarCaps, a product that has since been USA Today

Judge blocks suspension of 2 Vikings  -  ‎Jul 10, 2009‎
They took the weight-loss supplement StarCaps, which contained a diuretic, bumetanide, that wasn't listed on the label. The NFL wants to enforce the Philadelphia Inquirer

Saints' Will Smith's Battle Not Over Yet  -  ‎Jul 9, 2009‎
...former teammate Deuce McAllister and two Minnesota Vikings players -- was suspended after testing positive for the banned substance bumetanide. WDSU

Notebook: The Wall and Peterson  -  ‎Jul 2, 2009‎
The five players are accused of using the diuretic StarCaps that was spiked with the banned substance bumetanide, an ingredient that wasn't listed on the OU Insider

Saints' McCray says he'll win starting job  -  ‎Jun 23, 2009‎
Grant and Smith tested positive for the banned substance bumetanide last year, which was in a diuretic they took called StarCaps. With those two sidelined, Pro Football Weekly

Saints DE Smith expected to bounce back after rough season  -  ‎Apr 18, 2009‎
Smith and Grant were suspended after testing positive for StarCaps, a water pill that contains bumetanide, which is banned by the NFL. Pro Football Weekly

Vikings excited about their defense, if everyone stays healthy  -  ‎Apr 5, 2009‎
The Williamses, who are not related, were suspended after testing positive for Bumetanide, a diuretic contained in a weight-loss supplement called StarCaps. Pioneer Press

Dr. Bill Elliott: Some 'natural' products can be anything but healthy  -  ‎Apr 5, 2009‎
StarCaps, which has been widely promoted, was found to contain bumetanide (Bumex - a powerful diuretic). Some of the other undeclared pharmaceutical Marin Independent-Journal

Too Good to Be True  -  ‎Apr 1, 2009‎
...and the diuretic bumetanide. No prescription drug—even a diet aid like an appetite suppressant—should be taken without medical supervision. Newsweek

Study: Diuretic may put women at risk  -  ‎Apr 5, 2009‎
The group of prescription medications, which includes furosemide, torsemide, bumetanide and ethacrynic, work by easing the heart's workload, Memphis Commercial Appeal

10-K: CHINA MEDICINE CORP  -  ‎Mar 31, 2009‎
...the distribution of pharmaceutical products from suppliers, the distribution of self-developed pharmaceutical products (including Bumetanide injection, MarketWatch (press release)

Geneesmiddelenfabriek dicht door buitenlandse concurrentie  -  ‎Apr 12, 2009‎
Onder andere de door nier- en transplantatiepatiënten gebruikte medicijnen captopril, prednison, azathioprine en bumetanide horen tot het assortiment van NierNieuws.nl

10-K: CHINA PHARMA HOLDINGS, INC.  -  18 Mar 2009
In 2008, we launched a new diuretic product: Bumetanide; in November 2008, we were granted approval for our new formulation antibiotic to enter clinical MarketWatch (press release)

Trial date set for Kevin, Pat Williams  -  ‎Feb 25, 2009‎
Kevin and Pat Williams, who are not related, along with three New Orleans Saints players, were suspended after testing positive for bumetanide, ESPN

Authorities drop charges against Vilma  -  ‎Feb 25, 2009‎
The five players tested positive for Bumetanide, a banned substance under the NFL’s steroids and related substance policy. All five players claimed the SunHerald.com (subscription)

Sports briefs  -  ‎Feb 26, 2009‎
The players' union has said the league didn't properly inform the players that a supplement called StarCaps contained the banned diuretic bumetanide. Dubuque Telegraph Herald

NFL Notes: Jets' Coles a free agent  -  ‎Feb 25, 2009‎
The players' union has said the league didn't properly inform the players that a supplement called StarCaps contained the banned diuretic bumetanide. Asbury Park Press

FDA Releases Names of Drugs Now Available as Money-Saving Generics  -  ‎Feb 24, 2009‎
...(Feb 24, 2009)-- Each year, the Food and Drug Administration (FDA) approves scores of generic drugs that treat a wide variety of conditions and help Compliance Home

Diet Pills: Are They Natural or Not?  -  ‎Mar 4, 2009‎
Unfortunately for supporters like Kathie Lee Gifford, the popular supplement, StarCaps, was found to contain bumetanide, a diuretic that can cause Pierce Mattie Public Relations

Lions sign free-agent DT Jackson, CB Buchanon  -  ‎Mar 4, 2009‎
Some players said the banned substance Bumetanide was not listed as an ingredient in StarCaps, an over-the-counter weight-loss pill. The Associated Press

Tackle Grady Jackson expected to sign with Lions  -  ‎Mar 3, 2009‎
The still-pending suspensions resulted from the use of a weight-loss supplement -- called StarCaps -- that contained Bumetanide, a banned diuretic. DetNews.com

Magic pill, herb do not exist;  -  ‎Feb 25, 2009‎
...an anti-seizure medication, phenolphthalein, a solution used in chemical experiments and a suspected cancer causing agent and bumetanide, a diuretic. Benson News Sun

China Biotech in Review: Investments Continue  -  ‎Feb 22, 2009‎
Bumetanide; a hepatitis B treatment, Tiopronin Enteric-Coated Capsules; and Pusen OK, a generic version of cold medication Aleve-D. Sinobiomed (SOBM. Seeking Alpha

Your “Naturalâ€? Weight-Loss Supplement May Be a Health Hazard  -  ‎Feb 19, 2009‎
...“That product contained an active pharmaceutical ingredient that was, again, not declared, called bumetanide—a diuretic.� The FDA recently asked all the Health.com

NFL Free Agency Capsules: Giants sign Houston Texans safety CC Brown  -  ‎Mar 4, 2009‎
Some players said the banned substance Bumetanide was not listed as an ingredient in StarCaps, an over-the-counter weight-loss pill. Brownsville Herald

FDA Warns Consumers About Tainted Weight Loss Products  -  Jan 30, 2009
...(an anti-seizure medication), phenolphthalein (a solution used in chemical experiments and a suspected cancer causing agent) and bumetanide (a diuretic). InjuryBoard.com,

FDA expands list of tainted weight-loss products  -  Jan 15, 2009
The FDA analysis found that these products contained sibutramine, phenytoin, phenolphthalein, and bumetanide. One product, known as Phyto Shape, TheHeart.Org,

FDA Warns About Diet Pills  -  Jan 23, 2009
The FDA's Consumer Information website lists the weight-loss products that contain Sibutramine, Rimonabant, Phenytoin, Phenolphthalein, and Bumetanide, InjuryBoard.com,

Study looks at side effects of blood pressure medicine  -  Jan 21, 2009
Other loop diuretics include bumetanide (Burinex) and torasemide (Torem). They work well, but they do have side effects. One of the side effects is to guardian.co.uk,

China Pharma Wins Approval of Hepatitis Drug  -  Jan 13, 2009
Buflomedil, a treatment for peripheral blood vessel diseases; Roxithromycin dispersible tablet, a macrolide antibiotic; and Bumetanide, a newly approved Seeking Alpha,

FDA Publishes More Weight Loss Supplement Warnings  -  Jan 10, 2009
50 products which contain either rimonabant, phenolphthalein, phenytoin, bumetanide or sibutramine and which make no mention of them on the labeling. UKMedix Health News,

Brand Names/Synonyms:
Bumetanide is also known by the following brand names and/or synonyms:
B3023; Bumetanida [Inn-Spanish]; Bumetanide; Bumetanide [Usan:Ban:Inn:Jan]; Bumetanidum [Inn-Latin]; Bumex; Burine; Burinex; CHEMBANK404; EI-168; Fontego; Fordiuran; Lixil; Lunetoron; PF 1593; Segurex; [Inn-Spanish]

Drug Category:
Bumetanide is categorized under the following by the FDA: Diuretics; ATC:C03CA02

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid





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