Bupivacaine

This page contains recent news articles, when available, and an overview of Bupivacaine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Bupivacaine
(when available)

Pharmacology and use:
Bupivacaine, a local amino amide-type anesthetic agent, is indicated for the production of local or regional anesthesia or analgesia for surgery, for oral surgery procedures, for diagnostic and therapeutic procedures, and for obstetrical procedures. Bupivacaine blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. In general, the progression of anesthesia is related to the diameter, myelination and conduction velocity of affected nerve fibers. For the production of local or regional anesthesia or analgesia for surgery.

Mechanism Of Action:
Local anesthetics produce anesthesia by inhibiting excitation of nerve endings or by blocking conduction in peripheral nerves. Bupivicaine reversibly binds to and inactivates sodium channels (Voltage-gated sodium channel alpha subunit Nav1.8). Sodium influx through these channels is necessary for the depolarization of nerve cell membranes and subsequent propagation of impulses along the course of the nerve. When a nerve loses depolarization and capacity to propagate an impulse, the individual loses sensation in the area supplied by the nerve. The analgesic effects of Bupivicaine are thought to be due to its binding to the prostaglandin E2 receptors, subtype EP1 (PGE2EP1), which inhibits the production of prostaglandins, thereby reducing fever, inflammation, and hyperalgesia

News Articles on Bupivacaine

Rapid Chondrolysis of the Knee After Anterior Cruciate Ligament Reconstruction  -  ‎Jan 4, 2010‎
Although the exact cause of the severe acute chondrolysis in this patient remains unknown, the postoperative intra-articular infusion of bupivacaine is a ... Journal of Bone and Joint Surgery (subscription)

Court date set for epidural death case  -  ‎Dec 28, 2009‎
Immediately following the tragedy, Great Western Hospital led the way in changing the method in which bupivacaine was stored and hospitals across the UK ... Swindon Advertiser

Ultrasound-Guided Injection Can Benefit Lateral Hip Pain Small study shows ...  -  ‎Dec 29, 2009‎
...ultrasound-guided injection of 30 mg of triamcinolone combined with 3 mL of bupivacaine 0.5 percent using an anterior oblique coronal plane. ... ModernMedicine

Ultrasound Might Aid Treatment of Lateral Hip Pain  -  ‎Dec 22, 2009‎
...a gluteus medius peritendinous injection of 30 mg of triamcinolone combined with 3 mL of bupivacaine 0.5% with continuous ultrasound monitoring. ... MedPage Today

DURECT Reports Positive Phase IIb Data from POSIDUR(TM) Clinical Program  -  ‎Dec 17, 2009‎
It is intended to be administered during surgery, where it continuously releases therapeutic levels of bupivacaine in a controlled fashion, providing up to ... CNNMoney.com (press release)

علاج المÙ?اصل بالصÙ?ائح الدموية  -  ‎Jan 2, 2010‎
Ù?قد تلقى 15 شخصا حقنا بالصÙ?ائح الدموية، بينما تلقى 5 آخرون Ù?ÙŠ مجموعة مراقبة، حقنا من «بابوÙ?اكائين» bupivacaine وهو من الأدوية المخÙ?Ù?Ø© للألم. ... الشرق الاوسط

ì?˜í•™ 칼럼 - 목ì?˜ 통ì¦?ê³¼ 재활ì?˜í•™  -  ‎Dec 29, 2009‎
...전문ì?˜ì?˜ ì†?ì?„ 빌린 ì?´í•™ì ? 검사와 진단치료 목ì ?으로 fluroscopy하ì—? 0.5% Lidocaineì?´ë‚˜ 0.25% Bupivacaine으로 ì‹ ê²½ blockì?„ 함으로ì?¨ í?° ë?„움ì?„ 받습니다. ... 미주 한국일보

FDA warns of chondrolysis with continuously infused local anesthetics  -  14 Nov 2009
...bupivacaine, chlorprocaine, lidocaine, mepivacaine, procaine, ropivacaine) with elastomeric infusion devices to control post-surgical pain. ... Monthly Prescribing Reference

DURECT Corporation Announces Third Quarter 2009 Financial Results  -  ‎Oct 29, 2009‎
POSIDUR is our investigational post-operative pain relief depot that utilizes our patented SABER technology intended to deliver bupivacaine to provide up to ... Reuters

Bupivacaine Reduces Pain in Obese Children Recovering From Laparoscopic ...  -  ‎Oct 19, 2009‎
WASHINGTON, DC -- October 19, 2009 -- Bupivacaine is successful in reducing postoperative pain in children undergoing ... DG News

Medical Mistakes and Negligence Have Devastating Effects  -  ‎Nov 4, 2009‎
Before the procedure was to be repeated in 2008, Lee personally checked the dosage of bupivacaine to be administered. Shockingly, the dosage was again 10 ... 24-7PressRelease.com (press release)

Long-term Outcomes Data Validates the Utility of PROSTASCINT in Guiding ...  -  ‎Nov 4, 2009‎
EUSA also has several products in late-stage development, notably Collatamp® G topical, (gentamicin impregnated collagen sponge) and CollaRx®* (bupivacaine ... Reuters

Pacira's Phase III Study of EXPAREL(TM) Meets Primary Pain Relief Endpoint  -  ‎Oct 20, 2009‎
The company's most advanced product, EXPAREL(TM) (DepoBupivacaine), a bupivacaine-based product intended to deliver postoperative pain relief by ... Reuters

FDA Safety Changes: DepoDur, Neoral, Lexiva  -  ‎Nov 4, 2009‎
The FDA also warned that administration of morphine sulfate extended-release injection after an analgesic dose of the local anesthetic bupivacaine increases ... Medscape

Effect of Periarticular Corticosteroid Injections During Total Knee Arthroplasty  -  ‎Nov 2, 2009‎
The purpose of this double-blind study was to compare the clinical efficacy of periarticular injections consisting of bupivacaine, morphine, epinephrine, ... Journal of Bone and Joint Surgery (subscription)

Ultrasound Guidance Versus Electrical Stimulation for Femoral Perineural ...  -  ‎Oct 23, 2009‎
A double-blind comparison of ropivacaine, bupivacaine, and mepivacaine during sciatic and femoral nerve blockade. Anesth Analg 1998; 87:597–600. ... Journal of Ultrasound in Medicine (subscription)

Durect Corp. Reports Operating Results (10-Q)  -  ‎Nov 2, 2009‎
Durect Corp. is pioneering the treatment of chronic diseases and conditions by developing and commercializing pharmaceutical systems to deliver the right ... GuruFocus.com

New mother 'unlawfully killed' by blunder  -  Feb 5, 2008
Following the delivery, Bupivacaine, a potent epidural anaesthetic, ... During the failed resuscitation a 500ml Bupivacaine bag was found attached to the ... Independent

Mother died after epidural injected into her arm  -  Jan 8, 2008
The drip bag containing the anaesthetic Bupivacaine should have been connected to a line into the epidural space in the spinal cord. ... Telegraph.co.uk

… , randomized, double-blind comparison of bupivacaine and lidocaine...  -  Dec 10, 2005
Bupivacaine provides anaesthesia of about twice the duration of that with ... Pulp testing identified onset of anaesthesia with bupivacaine at a mean 6.53 ... Nature.com

Widower fights deportation order  -  Feb 8, 2008
Swindon & Marlborough NHS Trust had previously admitted liability in the case, which involved Bupivacaine toxicity. The inquest heard that the hospital's ... BBC News

Bupivacaine as pre-emptive analgesia in third molar surgery: randomise...  -  Mar 24, 2007
Studies report conflicting results on the ability of bupivacaine to reduce postoperative pain. In this study, 45 patients had bilaterally symmetrical ... Nature.com

… Establishes Corium as Manufacturer of TRANSDUR(TM)-Bupivacaine.  -  Feb 5, 2007
CUPERTINO, Calif., Feb. 5 /PRNewswire-FirstCall/ -- DURECT Corporation announced today that we have entered into a long term manufacturing and supply ... Free with registration - PR Newswire - AccessMyLibrary.com

Drugs mix-up 'led to nurse death'  -  Jan 17, 2008
Ms Rattigan admitted there had possibly been a similar mix-up with Bupivacaine in 1994, although her recollection was sketchy. ... BBC News

Innocoll Announces Initiation Of Phase IIA Clinical Study Of Bupivacai...  -  Mar 29, 2006
The study will examine the effects of the Bupivacaine collagen sponge on variables ... Innocoll's Bupivacaine collagen sponge is intended to provide pain ... Medical News Today - Medical News Today (press release)

EpiCept Licenses Patent for Bupivacaine in Back Pain to DURECT.  -  Dec 26, 2006
TARRYTOWN, NY, Dec. 26 /PRNewswire-FirstCall/ -- EpiCept Corporation (Nasdaq: EPCT; OMX Stockholm) today announced it entered into a license agreement with ... Free with registration - PR Newswire - AccessMyLibrary.com

… Augmentation; Local ketorolac and bupivacaine are effective...  -  Feb 26, 2005
2005 FEB 26 - (NewsRx.com & NewsRx.net) -- Locally administered intraoperative ketorolac and bupivacaine effectively reduces postoperative pain in breast ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

War veteran 'died after receiving wrong drug in operation'  -  Jun 4, 2008
Dr Stearns said the cause of death was bupivacaine and fentanyl toxicity, with ischaemic heart disease and chronic lymphocytic leukaemia as contributing ... Telegraph.co.uk

DURECT Starts Phase II Dosing for TRANSDUR(TM)-Bupivacaine (DUR- …  -  Jan 3, 2007
CUPERTINO, Calif., Jan. 3 /PRNewswire-FirstCall/ -- DURECT Corporation (Nasdaq: DRRX) today announced that we have started Phase II dosing in the US under ... Genetic Engineering News - Genetic Engineering News (press release)

Midwife denies epidural blunder  -  Jan 21, 2008
It was discovered after Mrs Cabrera's death that a bag of Bupivacaine fluid had been wrongly administered via a drip into her hand. ... BBC News

Madison nurse accused of negligence .  -  Nov 4, 2006
But Thao had started the intravenous drip with bupivacaine; soon, Gant began to convulse, have seizures and gasp for air. She was ... Milwaukee Journal Sentinel - Google News Archive

… Augmentation; Local ketorolac and bupivacaine are effective...  -  Feb 22, 2005
2005 FEB 22 - (NewsRx.com & NewsRx.net) -- Locally administered intraoperative ketorolac and bupivacaine effectively reduces postoperative pain in breast ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

DURECT Starts Phase II Dosing For TRANSDUR(TM)-Bupivacaine (DUR …  -  Jan 5, 2007
DURECT Corporation (Nasdaq: DRRX) today announced that we have started Phase II dosing in the US under an FDA-accepted Investigational New Drug (IND) ... Medical News Today - Medical News Today (press release)

Intra-Articular Injection of Bupivacaine in Knee-Replacement Operation...  -  May 1, 2006
The effectiveness of an intra-articular injection of bupivacaine, administered before the incision or after closure of the wound, was studied in an effort ... Journal of Bone and Joint Surgery - Journal of Bone and Joint Surgery...

Injection death inquest jury out  -  Feb 1, 2008
Midwife Marie To is alleged to have attached the Bupivacaine. She denied having done so in evidence. Swindon & Marlborough NHS Trust admitted liability but, ... BBC News

… of TRANSDUR(TM)-Bupivacaine. - PR Newswire | HighBeam  -  Feb 5, 2007
DURECT Establishes Corium as Manufacturer of TRANSDUR(TM)-Bupivacaine. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Innocoll Announces Initiation of Phase IIA Clinical Study of Bupivacai...  -  Mar 28, 2006
The study will examine the effects of the Bupivacaine collagen sponge on variables ... Innocoll's Bupivacaine collagen sponge is intended to provide pain ... Free with registration - PR Newswire - AccessMyLibrary.com

Midwife denies committing error over death of Pinoy mom in UK  -  Jan 22, 2008
It was later discovered that a bag of Bupivacaine fluid had been wrongly administered via a ... But To replied: "I did not put up Bupivacaine knowingly. ... GMA news.tv

… has much lower neurotoxic potential than racemic bupivacaine  -  Nov 1, 2005
..."Lower doses of levobupivacaine and bupivacaine had opposite effects on ... "In this particular model, both levobupivacaine and bupivacaine were ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

… Patent Applications for Its CollaRx(R) BUPIVACAINE IMPLANT for the...  -  Mar 30, 2007
The implant is a biodegradable and fully resorbable Bupivacaine-Collagen ... The CollaRx BUPIVACAINE IMPLANT is intended to provide pain control at the ... RedOrbit

… New Drug Application for its CollaRx(R) BUPIVACAINE TOPICAL for...  -  Oct 17, 2007
The CollaRx BUPIVACAINE IMPLANT is intended to provide pain control at the wound site ... The collagen matrix naturally biodegrades and the bupivacaine is ... Free with registration - PR Newswire - AccessMyLibrary.com

DURECT Announces Preliminary Results From Cohort 2 of Its On-Going …  -  Jun 20, 2005
SABER-Bupivacaine is based on DURECT's patented SABER delivery ... Of note, five of the ten patients receiving SABER-Bupivacaine in cohort 2 of our Phase II ... RedOrbit

Drugs, not alcohol, killed wife, court told  -  Jan 25, 2008
He said the presence of high levels of the anesthetics lidocaine and bupivacaine in her body was surprising and potentially fatal. ... Toronto Star

Bupivacaine Fails to Provide Relief from Pain Post-Tonsillectomy: …  -  Sep 22, 2006
By Louise Gagnon. TORONTO, CANADA -- September 22, 2006 -- The intraoperative use of bupivacaine in tonsillectomy did not lessen postoperative pain in ... DG News

… Starts Phase II Dosing for TRANSDUR(TM)-Bupivacaine (DUR-843). - PR...  -  Jan 3, 2007
DURECT Starts Phase II Dosing for TRANSDUR(TM)-Bupivacaine (DUR-843). from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… of Phase IIA Clinical Study of Bupivacaine Collagen Sponge. - PR N  -  Mar 28, 2006
Innocoll Announces Initiation of Phase IIA Clinical Study of Bupivacaine Collagen Sponge. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Event Brief of Q3 2005 DURECT Corporation Earnings Conference Call - ...  -  Oct 13, 2005
SABER-Bupivacaine is the Co.'s post-operative pain depot product. 2. The Co. is taking a local anaesthetic, bupivacaine, and administering it in a depot ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

EpiCept Amends DURECT Bupivacaine Patch Licensing Agreement  -  Sep 15, 2008
EpiCept Corporation (Nasdaq and OMX Nordic Exchange: EPCT) today announced that it has amended its December 20, 2006 licensing agreement with DURECT ... Genetic Engineering News - Genetic Engineering News (press release)

… an Update on Its Post-Operative Pain Depot (SABER(TM)-Bupivacaine)...  -  Apr 27, 2006
Based on the well known efficacy of immediate release bupivacaine, ... SABER-Bupivacaine injections also appeared to be well tolerated by patients. ... RedOrbit

Fishbein death accidental, autopsy shows  -  May 2, 2008
Adverse reactions to lower levels of bupivacaine are uncommon but have been described in medical books, Martin said. Fishbein went into cardiac arrest. ... Rocky Mountain News

DURECT Corporation Announces Fourth Quarter and Year End 2006 …  -  Feb 8, 2007
TRANSDUR-Bupivacaine. We announced that we had successfully completed Phase ... DURECT's Phase II program for TRANSDUR-Bupivacaine has begun in the US under ... Free with registration - PR Newswire - AccessMyLibrary.com

Press Release: DURECT Announces Preliminary Results from Cohort 2 …  -  Jun 20, 2005
SABER-Bupivacaine is based on DURECT's patented SABER delivery technology and is intended to be administered around the surgical site after surgery to ... Pay-Per-View - PR Newswire - HighBeam Research

Key witness 'medical hit man,' trial told  -  Feb 12, 2008
..."He's used far bigger doses (of lidocaine and bupivacaine) and he's never had any complications himself in his own practice," Hobson said. ... Toronto Star

… ; Pain management with intraoperative instillation of bupivacaine...  -  Sep 11, 2006
..."Pain perception was no different in the bupivacaine group compared with the ... "Women in the bupivacaine group were less nauseated than controls in the ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones

DURECT Corporation at BIO CEO & Investor Conference 2007 - Part …  -  Feb 14, 2007
And this is our TRANSDUR-Bupivacaine patch. ... Does that you're your Bupivacaine patch seem less appealing to potential partners? ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

Q2 2005 DURECT Corporation Earnings Conference Call - Final.  -  Jul 22, 2005
The opportunity here is to take Bupivacaine, which normally is quite infused ... It was very free flowing and felt similar to the Bupivacaine plus saline. ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

Bupivacaine Brings Post-Op Pain Relief for Women Undergoing …  -  May 6, 2008
By Carole Bullock. NEW YORK -- May 6, 2008 -- Bupivacaine demonstrated significantly better postoperative pain control in women undergoing mastectomy ... DG News

… ; Innocoll Technologies initiates Phase 2a clinical study of bupivac...  -  Apr 26, 2006
The study will examine the effects of the bupivacaine collagen sponge on variables ... Innocoll's bupivacaine collagen sponge is intended to provide pain ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Q4 2004 DURECT Corporation Earnings Conference Call - Final.  -  Feb 10, 2005
First, with regard to SABER-bupivacaine, we started our Phase II program. * Next, with regard to our DURIN-based Alzheimer's disease product, we started the ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

Study: Bupivacaine plus lidocaine comparable to levobupivacaine, …  -  Dec 28, 2007
When administered for peribulbar anesthesia, bupivacaine and lidocaine combined shows comparable efficacy to levobupivacaine alone and ropivacaine alone for ... OSN SuperSite

Event Brief of Q4 2005 DURECT Corporation Earnings Conference Call - ...  -  Feb 8, 2006
With respect to SABER-Bupivacaine, DRRX completed a Phase II study in over 80 patients. 2. ... With regard to SABER-Bupivacaine, which is the Co. ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

Effect Of Pre-Emptive Bupivacaine Infiltration On Post Thyroidectomy...  -  Jan 1, 2005
Effect Of Pre-Emptive Bupivacaine Infiltration On Post Thyroidectomy Pain Effect Of Pre-Emptive Bupivacaine Infiltration On Post Thyroidectomy Pain 45 ... Subscription - Internet Journal of Anesthesiology - EBSCO Publishing

Innocoll Files IND Application for CollaRx Bupivacaine Topical  -  Oct 22, 2007
Innocoll Technologies has filed an investigational new drug (IND) application for its CollaRx bupivacaine topical, which is under development for the ... FDA news - FDA news (subscription)

Alpharma Licenses Durect's Novel Bupivacaine Patch  -  Sep 22, 2008
BRIDGEWATER, NJ--(Marketwire - September 22, 2008) - Apharma Inc. ( NYSE : ALO), a leading global specialty pharmaceutical company, announced today that its ... marketwire.com

Preemptive Local Anesthesia at Surgical Site Reduces Incidence of …  -  Oct 16, 2006
...[Presentation title: Role of Pre-Emptive Analgesia with Bupivacaine for Chronic Pain after Laparoscopic Cholecystectomy. Abstract 348] DG News

SkyePharma in $80m anaesthetic deal  -  Apr 20, 2005
The result is that the duration of local anesthesia with bupivacaine can be extended for up to four days from around 8-12 hours with the current ... In-PharmaTechnologist.com

DURECT Corporation Announces First Quarter 2007 Financial Results.  -  May 7, 2007
POSIDUR is our post-operative pain relief depot that utilizes our patented SABER(TM) technology to deliver bupivacaine to provide up to three days of pain ... Free with registration - PR Newswire - AccessMyLibrary.com

Drug safety in Canada: 2 steps forward, 1 step back  -  Jan 3, 2006
Bupivacaine is a potent, potentially lethal local anesthetic that is used for ... The label on the bupivacaine Polyamp® ampoule sold by AstraZeneca does not ... CMAJ

Durect Wins Orphan Drug Designation for Bupivacaine  -  Jul 1, 2008
Durect has announced that the FDA has granted the company orphan drug designation for bupivacaine for relief of persistent pain associated with ... RedOrbit

Event Brief of Q4 2004 DURECT Corporation Earnings Conference Call - ...  -  Feb 10, 2005
SABER-Bupivacaine: Started Phase II programs. 3. ... SABER-Bupivacaine: 1. Used SABER controlled released injectable deeper (Phonetic) technology to develop ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

The unmasking of a Brugada phenotype after pulmonary resection: A …  -  Jul 3, 2007
The epidural solution consisted of 0.1% bupivacaine and 10 mg/mL of hydromorphone, ... There is 1 case report in the literature in which bupivacaine was ... The Journal of Thoracic and Cardiovascul...

Durect, Nycomed Agree On Pain Drug Marketing Deal  -  Dec 1, 2006
In the case of Posidur, the gel is combined with bupivacaine, a local anesthetic ... Yet while immediate-release bupivacaine only lasts four to six hours, ... BioWorld Online - BioWorld Online

Event Brief of Q1 2005 DURECT Corporation Earnings Conference Call - ...  -  May 3, 2005
Post-operative Pain Depot (SABER-Bupivacaine Program): 1. This is an application of the Co. ... Pharmacokinetic evaluation of the size of Bupivacaine level. ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

Doctor's anger at blunders  -  Jan 11, 2008
In a second blunder a midwife brought him another bag of Bupivacaine. ... He replied: "I was shocked to be handed a bag of Bupivacaine in the context of a ... This is Wiltshire.co.uk - This is Wiltshire.co.uk

Bupivacaine blocks digital nerve for nearly 25 hours.(Research …  -  Oct 1, 2006
Bupivacaine provides digital nerve blockade for approximately 25 hours, significantly longer than lidocaine alone or with epinephrine. ... $4.95 - Dermatology Times - ECNext

DURECT Corporation Announces Third Quarter 2007 Financial Results.  -  Nov 1, 2007
ELADUR(TM) (TRANSDUR-Bupivacaine). We have completed enrollment of patients and expect to report results in 2007 from a Phase IIa trial designed to assess ... Free with registration - PR Newswire - AccessMyLibrary.com

Article: Drug storage was chaotic.(News) - The Journal (Newcastle, …  -  Feb 6, 2008
A bag of Bupivacaine, an epidural anaesthetic, had been ... ... Article: Bupivacaine inhibits whole blood coagulation in vitro ... Pay-Per-View - The Journal - HighBeam Research

Illinois Administrative Code - 77 Ill. Adm. Code 790.1721 BUPIVACAINE...  -  Aug 10, 2005
77 Ill. Adm. Code 790.1721 BUPIVACAINE HYDROCHLORIDE; EPINEPHRINE BITARTRATE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. ... Pay-Per-View - Illinois Administrative Code - Loislaw

Epidural injection does not reduce long-term pain for people with...  -  Jan 20, 2006
Dr van Wijck comments: "We conclude that one epidural injection of methylprednisolone and bupivacaine, applied in the acute phase of herpes zoster, ... PsychCentral.com

SkyePharma aims for $82m with sale of injectable business  -  Jan 10, 2007
The one on which the company is banking is DepoBupivacaine (bupivacaine), a long-acting injectable formulation of local anaesthetic bupivacaine for the ... In-PharmaTechnologist.com

… of Investigational New Drug Application for Its CollaRx(R) BUPIVACA...  -  Mar 1, 2007
The implant is a biodegradable and fully resorbable Bupivacaine-Collagen ... The CollaRx BUPIVACAINE IMPLANT is intended to provide pain control at the ... Pay-Per-View - PR Newswire - HighBeam Research

Countering the effects of drug overdose  -  Aug 15, 2006
The scientists found that the nanoparticles extracted 81 percent amitriptyline and 62 percent bupivacaine in five minutes from a saline solution at 37 ... Chemistry World

Caudal Analgesia In Paediatrics: A Comparison Between Bupivacaine …  -  Aug 30, 2006
Caudal Analgesia In Paediatrics: A Comparison Between Bupivacaine And Ketamine Caudal Analgesia In Paediatrics: A Comparison Between Bupivacaine And ... Subscription - Internet Journal of Anesthesiology - EBSCO Publishing

Innocoll cleared to start Ph II with CollaRx bupivacaine implant.  -  Apr 9, 2007
Innocoll cleared to start Ph II with CollaRx bupivacaine implant. Innocoll, a privately-held US specialty pharmaceutical company, says that the Food and ... $9.94 - Pharma Marketletter - Alacra Store

Study of a Bupivacaine patch (Eladur[TM]) to treat postherpetic...  -  Nov 1, 2007
Sponsored by Durect. This study will test the safety and efficacy of treating postherpetic neuralgia patients with the analgesic patch, Bupivacaine TTS ... $4.95 - Journal of Drugs in Dermatology - ECNext

DURECT Signs POSIDUR(TM) Manufacturing Agreement with Hospira  -  Jan 29, 2007
POSIDUR (SABER(TM)-Bupivacaine) is a long-acting local anesthetic under development by DURECT for the treatment of post-surgical pain. ... Genetic Engineering News - Genetic Engineering News (press release)

Durect teams with Nycomed in $202M agreement  -  Nov 29, 2006
It is intended to be injected during surgery, where it continuously releases therapeutic levels of bupivacaine in a controlled fashion. San Jose Business Journal - San Jose Business Journal (subscription)

… Patent Applications for its CollaRx(R) BUPIVACAINE IMPLANT for the...  -  Mar 29, 2007
The implant is a biodegradable and fully resorbable Bupivacaine-Collagen ... The CollaRx BUPIVACAINE IMPLANT is intended to provide pain control at the ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: EpiCept Licenses Patent for Bupivacaine in Back Pain...  -  Dec 26, 2006
EpiCept Licenses Patent for Bupivacaine in Back Pain to DURECT. from PR Newswire Europe. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire Europe - HighBeam Research

… Laparoscopic Procedures With Intraperitoneal Bupivacaine  -  Jul 1, 2006
Post-Operative Pain Relief After Operative Gynecological Laparoscopic Procedures With Intraperitoneal Bupivacaine Post-Operative Pain Relief After Operative ... Subscription - Internet Journal of Gynecology and... - EBSCO Publishing

Press Release: EpiCept Licenses Patent for Bupivacaine in Back Pain...  -  Dec 26, 2006
EpiCept Licenses Patent for Bupivacaine in Back Pain to DURECT. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Illinois Administrative Code - 77 Ill. Adm. Code 790.1719 BUPIVACAINE...  -  Aug 10, 2005
77 Ill. Adm. Code 790.1719 BUPIVACAINE HYDROCHLORIDE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

Midwife accused of 'gross failure'  -  Jan 25, 2008
The 30-year-old, from Liden, died of Bupivacaine toxicity just an hour after giving birth to son Zac on the morning of May 11, 2004. ... Swindon Advertiser

Ultrasound delivers more accurate pain relief  -  May 1, 2006
They use a low-dose and a low volume of a local anesthetic called bupivacaine. Then, they attach the catheter to a bottle that contains a balloon filled ... News 8 Austin

Paravertebral Block for Pain Control in Percutaneous Transhepatic...  -  Apr 3, 2006
Bupivacaine 0.5% at a dose of 10 mL to 12 mL was injected into the right paravertebral space at 2 levels, T 8-9 and T 9-10. The procedure took about 10 to ... DG News

Press Release: Innocoll Announces Dosing of First Patient in a Second...  -  Mar 13, 2008
Innocoll's BUPIVACAINE SURGICAL IMPLANT is a biodegradable and fully ... This extended action was achieved despite a low total bupivacaine dose (150mg as ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Innocoll Announces Dosing of First Patient in a Third...  -  Jul 28, 2008
Innocoll's BUPIVACAINE SURGICAL IMPLANT is a biodegradable and fully bioresorbable matrix of purified fibrillar collagen impregnated with the local ... Pay-Per-View - PR Newswire - HighBeam Research

Thornhill doctor sentenced to 7 years for wife's death  -  Jun 5, 2008
Alcohol, along with anesthetics lidocaine and bupivacaine, were found in Mrs. Roncaioli's blood. Court heard the combination of those two drugs could be ... YorkRegion.com

Roncaioli may kill self, psychiatrist tells court  -  May 6, 2008
Alcohol, along with anesthetics Lidocaine and Bupivacaine were found in Ms Roncaioli's blood. Court heard the combination of those two drugs could be fatal. ... Liberal

Press Release: Innocoll Receives FDA Approval to Commence Phase 2 …  -  Apr 4, 2007
The implant is a biodegradable and fully resorbable Bupivacaine-Collagen Sponge ... Bupivacaine-Collagen Sponge formulated using Innocoll's proprietary ... Pay-Per-View - PR Newswire - HighBeam Research

Dramatic Government Intervention Allows NHS Negligence Widower To …  -  Aug 5, 2008
...at the Great Western Hospital when a midwife mistakenly hooked up a drip to her arm of Bupivacaine, a potent anaesthetic to be administered epidurally. ... Medical News Today - Medical News Today (press release)

New study shows epidural during birth may negatively affect …  -  Nov 12, 2006
...had no analgesia were breastfeeding at 24 weeks compared with 53% who received pethidine or epidurals containing bupivacaine and fentanyl (an opioid). ... innovations report - Innovations-Report

Occipital Nerve Block for Migraine Headaches  -  Dec 11, 2006
Occipital nerve block is a procedure where anesthetic agents (lidocaine and bupivacaine) are injected near the occipital nerve on the back of the head near ... HealthCentral.com

San Diego Business Journal Online - business news for San Diego, …  -  Dec 26, 2006
...worldwide rights to certain EpiCept intellectual property for a transdermal patch containing bupivacaine for the treatment of back pain. ... San Diego Business Journal - San Diego Business Journal

DURECT Announces Positive Preliminary Results From Its Phase II Study...  -  Oct 18, 2005
SABER-Bupivacaine is based on DURECT's patented SABER delivery technology and is intended to be administered around the surgical site after surgery to ... RedOrbit

… an Update on Its Post-Operative Pain Depot (SABER(TM)-Bupivacaine)...  -  Apr 27, 2006
Based on the well known efficacy of immediate release bupivacaine, ... SABER-Bupivacaine injections also appeared to be well tolerated by patients. ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Innocoll Announces Dosing of First Patient in US Phase...  -  Jan 4, 2008
Innocoll's BUPIVACAINE SURGICAL IMPLANT is a biodegradable and fully bioresorbable matrix of purified fibrillar collagen impregnated with the local ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Innocoll Announces Dosing of Last Patient in US Phase...  -  Aug 8, 2008
Innocoll Announces Dosing of Last Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of ... Pay-Per-View - PR Newswire - HighBeam Research

DURECT Corporation Announces Completion of Dosing in Cohort 3 of its ...  -  Sep 19, 2005
SABER-Bupivacaine is based on DURECT's patented SABER delivery technology and is intended to be administered around the surgical site after surgery to ... $4.95 - PR Newswire - ECNext

… Phase 2 Clinical Development With Its CollaRx(R) BUPIVACAINE …  -  Apr 5, 2007
The implant is a biodegradable and fully resorbable Bupivacaine-Collagen ... The CollaRx BUPIVACAINE IMPLANT is intended to provide pain control at the ... Medical News Today - Medical News Today (press release)

… New Drug Application for its CollaRx(R) BUPIVACAINE TOPICAL for t  -  Oct 17, 2007
Innocoll Files Investigational New Drug Application for its CollaRx(R) BUPIVACAINE TOPICAL for the Treatment of Painful Chronic Skin Ulcers and Burns. from ... Pay-Per-View - PR Newswire - HighBeam Research

Anesthetics; Anesthetics have enantioselective actions on coronary …  -  Apr 23, 2005
In parallel experiments, we examined the effects of bupivacaine and ... In addition, the effect of bupivacaine on mitochondrial membrane potential was ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

University of Marburg; Anesthetics have enantioselective actions on …  -  Apr 20, 2005
In parallel experiments, we examined the effects of bupivacaine and ... In addition, the effect of bupivacaine on mitochondrial membrane potential was ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Anesthetics; Anesthetics have enantioselective actions on coronary …  -  Apr 19, 2005
In parallel experiments, we examined the effects of bupivacaine and ... In addition, the effect of bupivacaine on mitochondrial membrane potential was ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Anesthetics; Anesthetics have enantioselective actions on coronary …  -  Apr 18, 2005
In parallel experiments, we examined the effects of bupivacaine and ... In addition, the effect of bupivacaine on mitochondrial membrane potential was ... Pay-Per-View - Cardiovascular Week - Factiva, from Dow Jones

Anesthetics; Anesthetics have enantioselective actions on coronary …  -  Apr 18, 2005
In parallel experiments, we examined the effects of bupivacaine and ... In addition, the effect of bupivacaine on mitochondrial membrane potential was ... Pay-Per-View - Pain & Central Nervous System Week - Factiva, from Dow Jones

… New Drug Application for Its CollaRx(R) BUPIVACAINE IMPLANT for the  -  Mar 1, 2007
The implant is a biodegradable and fully resorbable Bupivacaine-Collagen ... The CollaRx BUPIVACAINE IMPLANT is intended to provide pain control at the ... $4.95 - PR Newswire - ECNext

Brand Names/Synonyms:
Bupivacaine is also known by the following brand names and/or synonymsAnekain; Bloqueina; Bupivacaine; Bupivacaine Hcl; Bupivacaine Hcl Kit; Bupivacine Hcl Preservative Free; Bupivan; Carbostesin; Cbupivacaine; Chirocaine; D,L-Bupivacaine; Dl-Bupivacaine; LAC-43; Marcaina; Marcaine; Marcaine Hcl; Marcaine Spinal; Sensorcaine; Sensorcaine Forte; Sensorcaine-Mpf Spinal

Drug Category:
Bupivacaine is categorized under the following by the FDA: Anesthetics; Local Anesthetics; ATC:N01BB01; ATC:N01BB10

Dosage Forms:
SOLUTION

Absorption:
Not Available

Interactions:
[an error occurred while processing this directive]



Chemical IUPAC Name:
1-butyl-N-(2,6-dimethylphenyl)-piperidine-2-carboxamide





Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy