Bupropion

This page contains recent news articles, when available, and an overview of Bupropion but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Bupropion
(when available)

Pharmacology and use:
Bupropion, an antidepressant of the aminoketone class and a non-nicotine aid to smoking cessation, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Compared to classical tricyclic antidepressants, Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotonin, and dopamine. In addition, Bupropion does not inhibit monoamine oxidase. Bupropion produces dose-related central nervous system (CNS) stimulant effects in animals, as evidenced by increased locomotor activity, increased rates of responding in various schedule-controlled operant behavior tasks, and, at high doses, induction of mild stereotyped behavior. For the treatment of depression and as aid to Smoking cessation.

Mechanism Of Action:
Bupropion selectively inhibits the neuronal reuptake of dopamine, norepinephrine, and serotonin; actions on dopaminergic systems are more significant than imipramine or amitriptyline whereas the blockade of norepinephrine and serotonin reuptake at the neuronal membrane is weaker for bupropion than for tricyclic antidepressants. The increase in norepinephrine may attenuate nicotine withdrawal symptoms and the increase in dopamine at neuronal sites may reduce nicotine cravings and the urge to smoke. Bupropion exhibits moderate anticholinergic effects.

News Articles on Bupropion

Biovail, GSK Accused of Generic Wellbutrin Delay  -  ‎Jan 4, 2010‎
The plaintiffs allege that Biovail and GSK maintained exclusivity of Wellbutrin XL (bupropion HCl) by filing baseless patent infringement suits against four ... FDA news (subscription)

UW-CTRI's Holiday Health Media Manipulation  -  ‎Dec 16, 2009‎
The study and press release boast six-month quitting rates of 29.9% in a group that combined use of both the nicotine lozenge and bupropion, ... WhyQuit (press release)

Smokers Using Combination Drug Therapies More Likely to Quit, Study Shows  -  ‎Dec 17, 2009‎
The most effective therapy for smokers who wished to quit involved a combination of bupropion SR and nicotine lozenges, revealed a study conducted by Dr. ... DrugWatch.com

Comparative Effectiveness of 5 Smoking Cessation Pharmacotherapies in Primary ...  -  ‎Dec 14, 2009‎
Patients were randomly assigned to five active pharmacotherapies: three monotherapies (nicotine patch, nicotine lozenge, and bupropion hydrochloride ... Cardiosource

Genetic Studies Offer Clues about Addiction Risks, Treatments  -  ‎Dec 30, 2009‎
Instead, these individuals may respond better to alternative treatments such as the antidepressant bupropion (marketed under the trade names Wellbutrin or ... GenomeWeb Daily News

Arena files for approval for weight loss drug  -  ‎Dec 22, 2009‎
Orexigen plans next year to file for approval of its drug, Contrave, which combines the antidepressant Wellbutrin, known generically as bupropion, ... Reuters

Is there hope for life with depression?  -  ‎Dec 22, 2009‎
Will I always be on these meds (I take 200 mg sertraline and 300 mg bupropion)? What about starting a family? That's nine-plus months without them and after ... CNN

Leave your cigs in the old decade  -  ‎Dec 29, 2009‎
Use one of the NHS-approved aids to tackle the addiction – nicotine replacement therapy, Varenicline or Bupropion. List why you want to stop smoking. ... Shields Gazette

Smoking: Why it is best to quit  -  ‎Dec 23, 2009‎
Medication like Chantix (varenicline, FDA-approved 2006) and Zyban (bupropion, FDA-approved 1997) help to decrease withdrawal symptoms by working in the ... San Gabriel Valley Tribune

Resolving to quit smoking - resources  -  ‎Dec 12, 2009‎
...and will help you make a decision about using medication during the process, like patches, gum, lozenges, bupropion or varenicline ( Chantix ). ... Examiner.com

Medicaid and Smoking: One state extends benefits and is helping the poor kick ...  -  ‎Dec 20, 2009‎
Yet effective ways to break the habit — from counseling and support groups to nicotine patches, gum and new prescription remedies like Chantix and bupropion ... The Post-Standard - Syracuse.com (blog)

Research from University of California in the area of depression quality of ...  -  ‎Dec 17, 2009‎
...(1974-2009) using key terms 'quality of life,' 'major depression,' and 'major depressive disorder,' and 'dopaminergic,' 'bupropion,' or 'modafinil. ... Behavioral Health Central (blog)

Meet “Meow Meowâ€?: Mephedrone is the Furry Friend Who Will Kill Your Children  -  ‎Dec 14, 2009‎
It's bupropion, also called Wellbutrin and Zyban. Which may not be plant food, but, as the fourth most frequently prescribed antidepressant, certainly has ... The Faster Times

Not All Drugs Are the Same After All  -  ‎Dec 18, 2009‎
Mr. Graedon worked with an independent laboratory, ConsumerLab.com, to test the drug, which in other generic versions is typically known as bupropion. ... New York Times

Restless leg syndrome and erection problems now linked in older men  -  ‎Jan 1, 2010‎
...(1) An example is the drug bupropion, marketed also as Wellbutrin, and the same types of drugs that can treat Parkinson's disease. ... Examiner.com

Brain serotonin-2 receptors in acute mania  -  ‎Dec 31, 2009‎
Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline. Br J Psychiatry 2006; 189: 124 –31. ... British Journal of Psychiatry

Une combinaison de thérapie pour arrêter de fumer  -  ‎Jan 4, 2010‎
La meilleure thérapie serait de jumeler le bupropion à libération prolongée à des pastilles de nicotine. On a demandé à 7 128 fumeurs s'ils désiraient ... Canoë

å°?æ–¼é‡?度憂鬱症併用抗憂鬱藥物治療比單用Fluoxetine更有效  -  ‎Jan 3, 2010‎
...研究çµ?æ?Ÿæ™‚,çµ?果顯示,雖然bupropionã€?fluoxetineå’Œvenlafaxine併用組比單用fluoxetine組有較多病患é?”到治療å??應(分別是65%ã€?68%å’Œ73%相較於54%),但並未é?”統計上的 ... 臺灣新浪網

Las combinaciones farmacológicas son mejores para dejar de fumar  -  ‎Dec 17, 2009‎
Y en ese entorno del "mundo real", la terapia farmacológica más efectiva fue una combinación de bupropion SR (Zyban de liberación prolongada) y caramelos de ... El Informador

å?¸çƒŸçއ大幅䏋é™? 引全国关注  -  ‎Dec 21, 2009‎
...在麻州的这个计划中,18至64å²?çš„Medicaidå?—ä¿?者å?¯ä»¥å?ˆèµ„格获得180日的戒烟è?¯ç‰©ï¼ŒåŒ…括戒烟è?¯Chantixå?Šbupropion,以å?Šæ¯?å¹´16次谘询期。共å?Œæ”¯ä»˜é‡‘é¢?ä¸?超过三美元,而且 ... 大纪元

Medicamentos ´a la carta´ contra el tabaquismo  -  ‎Dec 15, 2009‎
La terapia sustitutiva de la nicotina, la administración de Bupropion, y de Varenicline son las tres alternativas, según la Sociedad Española de Neumología ... La Provincia - Diario de Las Palmas

Le Qnexa et le Lorcaserin, médicaments pour la perte de poids, soumis à la FDA  -  ‎Dec 29, 2009‎
Ce médicament est une combinaison de bupropion (Wellbutrin, un antidépresseur notamment utilisé pour aider le sevrage tabagique) et naltrexone (Revia ou ... PsychoMédia

IQWiG startet Kosten-Nutzen- Bewertung  -  ‎Dec 18, 2009‎
Das Kölner Institut soll die Wirkstoffe Venlafaxin, Duloxetin, Bupropion und Mirtazapin mit weiteren zu Lasten der Kassen verordnungsfähigen Antidepressiva ... apotheke-adhoc

"Konsument" testete verschiedene nikotinfreie Therapiehilfen zur Raucherentwöhnung  -  ‎Dec 18, 2009‎
Zyban: Ebenfalls rezeptpflichtig, der Wirkstoff Bupropion (Amfebutamon) wird auch zur Behandlung depressiver Erkrankungen eingesetzt. ... derStandard.at

Patch plus lozenge helps smokers quit longer  -  14 Nov 2009
..."While the nicotine lozenge, bupropion, and bupropion plus lozenge produced effects that were comparable with those reported in previous research," the ... Cancerfacts.com

Nicotine Patch Plus Lozenge Best for Quitting Smoking  -  ‎Nov 2, 2009‎
...nicotine lozenge, nicotine patch, bupropion (Wellbutrin, an antidepressant), nicotine patch plus nicotine lozenge, and bupropion plus nicotine lozenge. ... U.S. News & World Report

Varenicline May Not Be Linked to Increased Risk for Self-Harm  -  ‎Nov 9, 2009‎
During follow-up, the initial drugs prescribed were nicotine replacement products in 63265 patients, varenicline in 10973 patients, and bupropion in 6422 ... Medscape

Nicotine Patch Plus Lozenge Best Therapy for Smoking Cessation  -  ‎Nov 5, 2009‎
During treatment, the patch, bupropion plus lozenge, and patch plus lozenge were all significantly more efficacious than placebo, but at 6 months, ... Medscape

Use of Pharmacotherapy for Smoking Cessation in Italy  -  ‎Nov 9, 2009‎
In a cluster-randomized smoking cessation trial conducted in Germany on 577 smokers, cost-free nicotine replacement therapy (NRT) or bupropion hydrochloride ... Archives of Internal Medicine

COR trials: Combination bupropion, naltrexone improved cardiometabolic risk ...  -  ‎Oct 29, 2009‎
New data from the COR program demonstrate significant improvement in markers of cardiometabolic risk with combination sustained-release bupropion and ... Endocrine Today

EEG Biomarker May Reveal if Antidepressant Is Working  -  ‎Nov 6, 2009‎
In the BRITE-MD study, two-thirds of the participants were randomly switched to either bupropion or the bupropion-escitalopram combination after taking ... Psychiatric News

Orexigen(R) Therapeutics Announces Contrave(R) Data Presentations at Annual ...  -  ‎Oct 21, 2009‎
...the schedule of its upcoming Contrave® (naltrexone SR/bupropion SR) data presentations at the 27th Annual Scientific Meeting of The Obesity Society. ... Reuters

Companies Race To Bring Diet Drugs To Market  -  ‎Oct 28, 2009‎
Essentially, bupropion stimulates cells in the hypothalamus, a regulatory center in the brain, that curb appetite, and the naltrexone blocks endorphins, ... NPR

Orexigen(R) Therapeutics Announces Third Quarter 2009 Financial Results  -  ‎Nov 4, 2009‎
These new data show that after completing 56 weeks of therapy with Contrave32 (bupropion SR 360 mg/naltrexone SR 32 mg): -- Approximately 34-48% of patients ... Reuters

Even With Very Small Breast Tumors, Studies Find HER2 Status Matters  -  ‎Nov 3, 2009‎
...including nicotine replacement products (such as the nicotine patch) and non-nicotine medications (such as bupropion), can help people quit smoking. ... National Cancer Institute - NCI Cancer Bulletin

New systematic study for managing treatment-resistant bipolar depression  -  ‎Oct 27, 2009‎
Bupropion 75 mg was added 10 days later. After 3 weeks, the QIDS-SR score was 13 (moderate) without mania or hypomania. After 15 weeks, the QIDS-SR was 14 ... News-Medical.net

American Lung Association Urges Full Coverage of Clinically Proven Smoking  -  ‎Nov 10, 2009‎
These medications include over-the-counter and prescription nicotine-replacement-therapies and two non-nicotine prescription drugs: bupropion and ... PR Newswire (press release)

Does Chantix cause suicidal thoughts?  -  ‎Oct 22, 2009‎
Some received nicotine replacement therapy (about 63000), others received bupropion (Wellbutrin 6400), and others were on Chantix (11000). ... Eagle Tribune

What Did STAR*D Teach Us? Results From a Large-Scale, Practical, Clinical ...  -  ‎Oct 30, 2009‎
Mean daily dosage at the final visit for bupropion-SR was 282.7 mg, for sertraline it was 135.5 mg, and for venlafaxine-XR was it 193.6 mg. ... Psychiatric Services (subscription)

University of Wisconsin: World's Pharm Nicotine Sales Center  -  ‎Nov 12, 2009‎
Aside from the Commit lozenge, GlaxoSmithKline sells the Nicoderm CQ line of nicotine patches and the prescription quitting pill Zyban (bupropion). ... WhyQuit (press release)

The Role of Antidepressants for the Treatment of Bipolar Depression  -  ‎Nov 4, 2009‎
...with bipolar I or bipolar II disorder were treated with an antidepressant (bupropion, sertraline, or venlafaxine) in addition to a mood stabilizer. ... Psychiatric Times

Orexigen obesity drug seems to be effective  -  ‎Oct 24, 2009‎
It is to be noted that Contrave happens to be a pill known for combining the antidepressant Wellbutrin, famous commonly as bupropion, with a sustained- ... What is the Word

Personal Health: News and Notes  -  ‎Nov 9, 2009‎
...of Wisconsin compared five smoking- cessation treatments, including nicotine lozenges, nicotine patches, and the antidepressant bupropion sold as Zyban. ... Philadelphia Inquirer

3 new prescription diet drugs may soon help obese  -  ‎Oct 21, 2009‎
It combines two drugs now on the market — bupropion, an antidepressant and smoking cessation medication, and naltrexone, currently used for alcohol and ... USA Today

Which Antidepressants Treat Comorbid Anxiety and Depression?  -  ‎Oct 28, 2009‎
Augmenting agents include another antidepressant (eg, TCA, bupropion, or trazodone), thyroid hormone (synthetic T3), lithium, antiepileptic medications, ... Medscape

This Month in Archives of General Psychiatry  -  ‎Nov 2, 2009‎
One thousand five hundred four adults who smoked 10 or more cigarettes per day were randomized to 1 of 6 conditions: sustained-release bupropion, ... Archives of General Psychiatry

CHEST: Varenicline Helps Patients with COPD Quit Smoking  -  ‎Nov 4, 2009‎
Varenicline and bupropion are the two first-line pharmacologic aids for smoking cessation recommended by the Department of Health and Human Services' Public ... MedPage Today

Nearly Half of Patients to Try Experimental Diet Drug Shed 10 Percent of Body ...  -  ‎Oct 26, 2009‎
Contrave is a pill that combines the antidepressant Wellbutrin, known generically as bupropion, with a sustained- release version of naltrexone, ... FOXNews

No Clear Winner as Top Obesity Candidates Reveal Detailed Data  -  ‎Oct 26, 2009‎
...while Orexigen Therapeutics Inc.'s Contrave (bupropion SR/naltrexone SR) came in at 4.2 percent to 5.2 percent. Arena Pharmaceuticals Inc.'s lorcaserin, ... BioWorld Online

Orexigen(R) Therapeutics Releases New Efficacy Data for Contrave(R) in Late ...  -  ‎Oct 27, 2009‎
COR-I and COR-II Phase 3 trials of Contrave® (naltrexone SR/bupropion SR), the first of two late stage Orexigen candidates for the treatment of obesity. ... Reuters

Orexigen(R) Therapeutics Presents New Data Showing Weight Loss with Contrave ...  -  ‎Oct 24, 2009‎
...new data from the COR-I, COR-II and COR-Diabetes trials for Contrave® (bupropion SR/ naltrexone SR) to expand on top-line results announced in July. ... Reuters

Combination drugs for weight loss  -  ‎Oct 29, 2009‎
MA) and colleagues presented data from a phase 3 randomized controlled trial comparing the efficacy and safety of naltrexone and bupropion (Orexigen ... TheHeart.Org

22nd Century Continuing Development of its Smoking Cessation Aid; Independent ...  -  ‎Oct 27, 2009‎
Smokers currently have few choices of FDA-approved products for smoking cessation: varenicline (Chantix), bupropion (Zyban), and nicotine in several forms ... Reuters

Researchers find effective way to quit smoking  -  ‎Nov 4, 2009‎
The study compared nicotine patches, nicotine lozenges and a combination of the two; bupropion — a prescription medication — and its combination with the ... UW Badger Herald

Three biotechs race for Holy Grail of drug development  -  ‎Oct 19, 2009‎
Orexigen also combines two generics, including the well known antidepressant bupropion. Only Arena's Lorcaserin is a new drug. But a history of serious side ... FierceBiotech

Nicotine Patch And Lozenge Most Effective At Helping Smokers Quit  -  ‎Nov 7, 2009‎
The participants were divided into six treatment groups involving different treatment methods like nicotine lozenge group, nicotine patch group, bupropion ... india-server.com

New weight loss drugs on the horizon!  -  ‎Nov 7, 2009‎
...•Contrave:This medication combines two drugs already on the market — bupropion, an antidepressant and smoking cessation medication (also known as Zyban or ... Drumheller Mail

Three new prescription diet drugs for the obese on FDA roadmap  -  ‎Oct 22, 2009‎
Contrave from Orexigen: combines two drugs, bupropion, an antidepressant and smoking cessation medication, and naltrexone, currently used for alcohol and ... ChattahBox

A Doctor's Word--Tips to Escape the Smoking Trap  -  ‎Oct 20, 2009‎
Varenicline can be used alone, while bupropion and nicotine replacement are often used together. Jones has been using patches alone with success. ... New America Media

BREAKING NEWS: Relenza helps GSK return to sales growth  -  ‎Oct 28, 2009‎
The antidepressant Wellbutrin (bupropion) slumped 70% to £16 million, reflecting the sale in May of the US rights to Wellbutrin XL in the USA to Biovail for ... Pharma Times

Michael Cowley, Obesity Expert, Named Life Scientist Of The Year  -  ‎Oct 31, 2009‎
Contrave combines new formulations of two existing drugs: Bupropion, an antidepressant; and Naltrexone, an addiction medication. ... Medical News Today (press release)

El Gobierno vasco moviliza a su personal sanitario en la lucha contra el tabaco  -  ‎Nov 9, 2009‎
Como ejemplo, un tratamiento de dos meses con pastillas de bupropion, que inhibe el deseo de fumar, cuesta entre 130 y 150 euros -algo similar al dinero que ... El Correo Digital (Vizcaya)

Patchs et pastilles de nicotine : la combinaison fait mouche !  -  ‎Nov 12, 2009‎
Patchs, chewing-gums, pastilles à sucer, bupropion… Pas facile, de choisir un traitement pour cesser de fumer ! Selon une étude américaine, l'association de ... Destination Santé

Røykeslutt: Bupropion mer effektivt enn narremedisin  -  ‎Nov 3, 2009‎
Bupropion ser ut til å hjelpe flere til å slutte å røyke enn narremedisin (placebo). Det viser en gjennomgang Cochrane-samarbeidet har gjort. ... Nasjonalt kunnskapssenter for helsetjenesten

La cruzada antitabaco se cuela en Internet  -  ‎Nov 2, 2009‎
...parches de nicotina; el antidepresivo bupropion; parches combinados con pastillas de nicotina; bupropion más pastillas de nicotina y un placebo. ... Expansión.com

Bei der medikamentösen Unterstützung der Raucherentwöhnung erwies sich die ...  -  ‎Nov 9, 2009‎
Die Behandlung mit Bupropion wurde eine Woche vor der Abstinenz begonnen und acht Wochen lang durchgeführt. Die anderen Behandlungen begannen unmittelbar ... DKG Krebsgesellschaft

Pflaster plus Pastille wirkt am besten  -  ‎Nov 4, 2009‎
Sie wurden in sechs Gruppen unterteilt und erhielten zur Raucherentwöhnung Nicotinpastillen, Nicotinpflaster, Bupropion, Pflaster plus Pastille, Bupropion ... DAZ.online

Kein leichter Weg zur Raucherabstinenz: Fünf medikamentöse Hilfen im ...  -  ‎Nov 3, 2009‎
Die Bupropion-Behandlung wurde eine Woche vor der Abstinenz begonnen und über acht Wochen fortgesetzt. Alle anderen Therapien begannen mit der letzten ... Deutsches Ärzteblatt

La pilule Contrave de Orexigen fait perdre 10 à 15% de poids  -  ‎Oct 26, 2009‎
La pilule Contrave mélange deux principes actifs bien connus et utilisés depuis plus de 20 années : bupropion (un antidépresseur également prescrit aux ... RegimesMaigrir.com

비만실험약 '콘트ë?¼ë¸Œ' 3ìƒ?ìž„ìƒ? 목표 ë?„달  -  ‎Oct 25, 2009‎
...콘트ë?¼ë¸ŒëŠ” 항우울제 '웰부트린(Wellbutrin, bupropion)'ê³¼ 알코올 중ë?… 치료제로 사용ë?˜ëŠ” 날트렉ì†?(naltrexone)ì?˜ 복합제. 지난 7ì›” 발표ë?œ ìž?료ì—? 따르면 첫 번째 ... 데일리팜

Parches y pastillas de nicotina elevan éxito cesación tabáquica  -  ‎Nov 5, 2009‎
...pastillas de nicotina, parches de nicotina, bupropion de liberación prolongada (Wellbutrin), parche más pastilla, bupropion más pastilla o placebo. ... Público

Chantix ayuda a las personas con enfisema a dejar de fumar  -  ‎Nov 10, 2009‎
En julio, la Administración de Alimentos y Medicamentos de Estados Unidos (FDA, por sus siglas en inglés) exigió que Chantix y Zyban (bupropion), ... Público

Nikotinersatz bald auf Rezept?  -  ‎Oct 22, 2009‎
Auch die als Lifestyle-Präparate ausgeschlossenen verschreibungspflichtigen Raucherentwöhnungsmedikamente Zyban (Bupropion) und Vareniclin (Champix) sollen ... apotheke-adhoc

Sanidad creará unidades especializadas en tabaquismo para avanzar en la ...  -  ‎Nov 10, 2009‎
...las terapias de sustitución de la nicotina -parches, chicles, sprays- o medicamentos como el Bupropion, la Vareniclina, la Clonidina o la Nortriptilina. ... Noticias de Álava

Bupropion doesn't prevent smoking in ADHD patients  -  Aug 29, 2007
By Will Boggs, MD. NEW YORK (Reuters Health) - The high risk of smoking among young people with attention-deficit/hyperactivity disorder (ADHD) is not ... Reuters UK

FDA ruling seen delaying Biovail's bupropion  -  Nov 20, 2007
By Scott Anderson. TORONTO, Nov 20 (Reuters) - The US Food and Drug Administration dealt a blow to Biovail Corp's (BVF.TO) (BVF.N) hopes for quick approval ... Reuters

A switch to bupropion might reverse sexual dysfunction  -  Oct 13, 2008
I have been taking Prozac for five years. I've definitely noticed a downturn in my ability to achieve a climax. My doctor switched me to Celexa to see if it ... Los Angeles Times

… P450 2B6 activity as measured by bupropion hydroxylation: Effect...  -  Dec 8, 2005
Blood samples were taken for up to 72 hours after each bupropion dose, ... Rifampin treatment decreased the half-life of bupropion from 15.9 hours (95% CI, ... Nature.com

New drug shows promise in helping smokers quit.  -  Jul 5, 2006
Nicotine-replacement compounds, such as bupropion and patches, are commonly used to help people quit, but their success rate is only moderate. ... Free with registration - Chicago Tribune - AccessMyLibrary.com

Biovail awaits response from FDA on bupropion  -  Oct 24, 2007
TORONTO, Oct 24 (Reuters) - Biovail Corp (BVF.TO) (BVF.N) said on Wednesday it submitted a response to the US Food and Drug Administration's non-approval ... Reuters

Generic Bupropion Antidepressant Safe, Effective: FDA  -  Apr 16, 2008
Teva Pharmaceuticals' version of generic bupropion extended-release tablets (marketed as Budeprion XL 300 milligram) is a safe and effective choice for the ... Washington Post

Bupropion hydrochloride (Zyban) for quitting smoking  -  Jul 24, 2007
Bupropion is a pill you take to reduce your craving for tobacco. The way it does this is not entirely known. Bupropion does not contain nicotine and does ... WebMD

Anti-smoking drug may cut crystal meth craving  -  Nov 29, 2005
Bupropion - the active chemical ingredient found in the nicotine addiction drug ... The users given doses of bupropion reported experiencing a significantly ... New Scientist

A Genetic Clue to Quitting Smoking  -  Jun 2, 2008
Bupropion, on the other hand, is an antidepressant, which does not contain nicotine; instead, it works to curb nicotine cravings by interfering with the ... TIME

The Nation; Study Suggests Antidepressant May Help Treat Meth …  -  Nov 23, 2005
A common antidepressant, bupropion, can reduce the craving for methamphetamine ... Bupropion, sold under the trade name Wellbutrin, has long been used as an ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Chantix: New stop smoking medication to help you quit  -  Nov 16, 2006
Chantix also appears to work better than the antidepressant bupropion, ... Others found Chantix worked better than bupropion for up to a year after ... CNN International

No Evidence for a Major Role of Polymorphisms During Bupropion …  -  Aug 15, 2005
However, no polymorphisms or their interactions with bupropion consistently ... Bupropion, an antidepressant medication with effects on dopamine reuptake ... Nature.com

FDA says Budeprion antidepressant is safe  -  Apr 16, 2008
The FDA said it evaluated the reports concerning the generic version of bupropion hydrochloride extended-release 300-milligram tablets and found the generic ... United Press International

Wellbutrin XL: bupropion extended-release tablets.(New indications)( …  -  Jul 1, 2006
This antidepressant of the aminoketone class is believed to exert its effect through inhibition of norepinephrine and dopamine reuptake. Bupropion was ... Free with registration - Formulary - AccessMyLibrary.com

New drug can help smokers quit - Smoking- msnbc.com  -  Jan 24, 2007
Three of these also included a comparison with bupropion, an antidepressant that is also used for smoking cessation. The six trials included 4924 smokers, ... msnbc.com

FDA Approves First Generic Bupropion Hydrochloride Extended-Release …  -  Dec 15, 2006
The US Food and Drug Administration (FDA) today approved the first generic version of Wellbutrin XL (Bupropion hydrochloride) Extended-Release Tablets, ... Free with registration - M2 Presswire - AccessMyLibrary.com

Biovail says FDA rejection won't affect outlook  -  Jul 23, 2007
Last week, the FDA rejected Biovail's application for a once-daily version of bupropion, citing concerns about pharmacokinetics, or the way the body absorbs ... Reuters

Extended-Release Bupropion Improves Symptoms in Adults With Major …  -  Oct 25, 2005
By Mark Pownall. AMSTERDAM, THE NETHERLANDS -- October 25, 2005 -- An extended-release version of bupropion appears to improve the symptoms of decreased ... DG News

Orexigen: Patent office issues notice of allowance for obesity drug …  -  Jan 31, 2008
Contrave is a proprietary fixed dose combination of bupropion sustained release and Orexigen's novel formulation of naltrexone sustained release in a single ... Forbes

Drug shows promise in helping smokers kick habit  -  Jul 7, 2006
This compared with about 30 per cent for bupropion, marketed as Zyban, and 17 per cent ... Nicotine-replacement compounds, such as bupropion and patches, ... Sydney Morning Herald

The Five Dumbest Things on Wall Street This Week  -  Jul 20, 2007
The Food and Drug Administration sent Biovail a nonapproval letter covering BVF-033, a drug candidate based on bupropion -- the active ingredient in Glaxo's ... TheStreet.com - TheStreet.com (subscription)

Intensive care helps smokers quit, study finds  -  Feb 13, 2007
Half then were given at least 12 weeks of behavior modification counseling and either nicotine replacement therapy, treatment with the drug bupropion, ... Reuters

Bupropion XL Effective and Safe in Elderly Patients With Major …  -  Sep 20, 2006
By Chris Berrie. PARIS, FRANCE -- September 20, 2006 -- Once-daily use of an extended-release formulation of bupropion (Wellbutrin XL(R)) is both ... DG News

Chantix controversy  -  Jun 9, 2008
...of people taking Chantix had stopped smoking at the end of 12 weeks, compared to 30 percent of people treated with bupropion, another prescription drug. ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Bupropion re-kindles interest in dopamine strategy for major depressio...  -  Nov 12, 2005
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FDA Approves First Generic Bupropion Hydrochloride Extended-Release …  -  Dec 28, 2006
The US Food and Drug Administration (FDA) today approved the first generic version of Wellbutrin XL (Bupropion hydrochloride) Extended-Release Tablets, ... Medical News Today - Medical News Today (press release)

Pill eases craving.(BIOMEDICINE)(Brief Article)  -  Nov 26, 2005
An experimental drug called varenicline helps smokers kick the habit better than does bupropion, the only drug currently prescribed for the task, ... Free with registration - Science News - AccessMyLibrary.com

Treating depression improves diabetes control  -  Mar 6, 2007
Researchers from Missouri treated 93 patients with type 2 diabetes and depression with the antidepressant bupropion (Wellbutrin). ... Reuters

… film containing nicotine and bupropion for combined smoking...  -  Feb 1, 2008
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Bupropion (Systemic).  -  Jul 28, 2005
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FDA Approves Wellbutrin XL(R) (bupropion HCI extended-release tablets...  -  Jun 12, 2006
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Bupropion, bupropion sustained release, bupropion extended release ( …  -  Jun 1, 2006
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Wellbutrin (bupropion) and tamoxifen  -  Mar 14, 2008
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Bupropion as Methamphetamine Addiction Treatment Hold Promise  -  Nov 26, 2005
By Semel Institute, UCLA, A new study led by researchers at UCLA's Semel Institute suggests the antidepressant bupropion may help treat methamphetamine ... RxPG NEWS

Orexigen Starts New Trial of Obesity Drug  -  May 22, 2007
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Anti-smoking drug backed by 3 studies -  -  Jul 5, 2006
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Value of Adding Bupropion to Nicotine Replacement  -  Jan 15, 2005
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Health Canada sounds antidepressant arning  -  Mar 10, 2006
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RIGOROUS TESTS OF GENERIC DRUGS ARE NOT AUTOMATIC  -  May 30, 2008
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Hikal, Crompton Manufacturing in alliance  -  Feb 23, 2005
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Bupropion [sustained release, extended release] (generic); Wellbutrin,...  -  Jan 1, 2006
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Orexigen(R) Therapeutics Presents Data on Its Proprietary Formulation...  -  Oct 6, 2008
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Efficacy of Bupropion and Nortriptyline for Smoking Cessation Among …  -  Oct 24, 2005
Background The observations that smokers with chronic obstructive pulmonary disease (COPD) are at increased risk of depression and that nicotine may have ... Archives of Internal Medicine

Generic Not Same as Brand Antidepressant?  -  Oct 12, 2007
The FDA is reviewing reports on Bupropion. Meanwhile, Todd Cooperman is planning to test other generic drugs, and Sheryl, who had problems with Bupropion, ... NPR

Bupropion XL and Venlafaxine XR for Treatment of Major Depression: …  -  May 25, 2006
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GOOD DIET MIGHT REPLACE PILLS  -  Jun 12, 2008
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Bupropion (Zyban) May Help Teens Quit Smoking  -  Nov 5, 2007
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The "Bupropion for Smoking Cessation" Trial From a Family Practice …  -  Feb 28, 2005
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Bupropion for the Treatment of Methamphetamine Dependence  -  Jun 20, 2007
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Bupropion XL Has Strong Antianxiety Properties: Presented at ADAA  -  Mar 29, 2006
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Gene impacts smoking cessation drug  -  Sep 11, 2007
11 (UPI) -- US and Canadian scientists have demonstrated a link between a genetic variant and the effectiveness of the smoking cessation drug bupropion, ... United Press International

Drug 'improves chances of kicking the habit'  -  Jan 25, 2007
Three of these also included a comparison with bupropion, an antidepressant that is also used for smoking cessation. The six trials included 4 924 smokers, ... Independent Online

Learn about Bupropion from Consumer Reports Health.  -  Jan 8, 2007
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Bupropion and Escitalopram Provide Similar Relief in Depressed...  -  Oct 28, 2005
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Study: bupropion-naltrexone combo best for weight loss.(Across …  -  Feb 1, 2008
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ShopSmart: Try nondrug treatments first for SAD  -  Oct 28, 2007
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Giving Up Cigarettes: Drugs That Raise the Odds  -  Jan 25, 2007
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… depression with venlafaxine, sertraline and bupropion.(What's New...  -  Jun 1, 2006
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Article: Abuse of bupropion.(EVIDENCE-BASED PSYCHIATRIC …  -  Sep 1, 2007
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Croatian Lucic on the comeback trail after troubled past  -  Mar 10, 2007
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Delirium associated with bupropion and fluoxetine.(Drug-Drug …  -  Mar 1, 2007
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How to take Bupropion from Consumer Reports Health.  -  Jan 8, 2007
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Obesity drug shows promise in testing  -  Jul 25, 2007
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Quit failure higher for young smokers - TVNZ Smartphone - tvnz.co.nz  -  Dec 28, 2006
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Bupropion and Nortriptyline for Smoking Cessation  -  May 15, 2006
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Don't let 2007 go up in smoke  -  Dec 29, 2006
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Drug rejection pummels Biovail shares  -  Jul 21, 2007
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Combined Bupropion and Naltrexone Shows Promise for Obesity: …  -  Jun 12, 2006
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Interactive Tool: How Much Is Smoking Costing You? - What's next?  -  Oct 11, 2007
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Substance abuse low among the obese, study says  -  Jul 11, 2006
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Bupropion SR vs. Buspirone for Treating Depression  -  Aug 15, 2006
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Disappointment for Biovail bupropion plans  -  Jul 25, 2007
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FDA Clears Generic Wellbutrin, Consumer Advocates Skeptical  -  Apr 18, 2008
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Varenicline gets fast-track nod for smoking cessation.(care and...  -  Jun 1, 2006
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OREXIGEN(TM) Therapeutics Reports Preclinical Results Showing …  -  Oct 23, 2007
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Bupropion as adjunct to patch yields long-term results.(Addiction …  -  Apr 1, 2007
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Pharmacology Watch: Reversal of Atherosclerosis Via Intensive Statin ...  -  May 1, 2006
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Investors reward Biovail rebound  -  Mar 11, 2005
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Bupropion effect much better in controlled trials.(Clinical Rounds)  -  Aug 1, 2005
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Pregnant women warned about antidepressant risk  -  Mar 11, 2006
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bupropion GlaxoSmithKline receives US FDA approval for prevention of ...  -  Jun 26, 2006
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New genetic research into nicotine addiction shows promise for …  -  Sep 17, 2007
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Strong efficacy data for GSK's bupropion, ahead of European filing...  -  Oct 31, 2005
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Bupropion boosts quitters' success.(Brief Article)  -  Nov 19, 2005
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Quick antidepressant effect seen with escitalopram/bupropion mix.( …  -  Oct 15, 2005
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Scientists Demonstrate Genetic Variant Is Linked To Effectiveness Of ...  -  Sep 20, 2007
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Brand Names/Synonyms:
Bupropion is also known by the following brand names and/or synonymsBupropion; Bupropion Hcl; Wellbatrin; Wellbutrin; Wellbutrin Sr; Wellbutrin Xl; Zyban

Drug Category:
Bupropion is categorized under the following by the FDA: Antidepressants; Antidepressants; ATC:N07BA02

Dosage Forms:
immediate and sustained release tablets

Absorption:
for sustained release, peak plasma conc. are achieved within 3 hours.

Interactions:
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Chemical IUPAC Name:
1-(3-chlorophenyl)-2-tert-butylamino-propan-1-one





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