Captopril

This page contains recent news articles, when available, and an overview of Captopril but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Captopril
(when available)

Pharmacology and use:
Captopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension, congestive heart failure, and renal syndromes such as diabetic nephropathy and scleroderma. For the treatment of hypertension. It may be used alone or in combination with thiazide diuretics

Mechanism Of Action:
Captopril competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. As angiotensin II is a vasoconstrictor and a negative feedback mediator for renin activity, lower angiotensin II levels results in a decrease in blood pressure, an increase in renin activity, and stimulation of baroreceptor reflex mechanisms. Kininase II, an enzyme which degrades the vasodilator bradykinin, is identical to ACE and may also be inhibited.

News Articles on Captopril

The Taming of the Heart Attack  -  ‎Jan 1, 2010‎
..."My father did one of the earliest studies with captopril, the first of the ACE-inhibitors," Cannon said. The trial studied the drug in the post-MI setting ... MedPage Today

Five Supplements to Watch in 2010  -  ‎Dec 28, 2009‎
ACE inhibitors such as brands Lotensin, Vasotec, and Captopril are used medically to block the action of angiotensin I to treat hypertension, ... eMaxHealth

Tratamiento de la encefalopatía hipertensiva  -  ‎Jan 4, 2010‎
Por otro lado, en un estudios con nifedipina versus captopril, ambas sublinguales, no se encontraron diferencias significativas. ... Intramed.net (Suscripción)

O prejuízo com a biopirataria  -  ‎Dec 27, 2009‎
...de recurso natural que gerou lucros imensos para a indústria farmacêutica e nenhum centavo para o país, que é o do anti-hipertensivo captopril. ... Gazeta do Povo Online

Ask Dr. H: She's had digestive distress since gall bladder removal  -  ‎Nov 9, 2009‎
Wellbutrin and Prozac; blood pressure medications like Norvasc, ACE inhibitors (Vasotec, Captopril) and clonidine; acid blockers like Tagamet, Prevacid, ... Philadelphia Inquirer

ACG: ACE Inhibitor Use Linked to Liver Toxicity  -  ‎Oct 26, 2009‎
Another report in 2001 detailed two additional cases and reviewed 13 prior cases, all involving use of captopril (Am J Med Sci 2001; 322: 236-40). ... MedPage Today

Predictors of Sudden Cardiac Death Change With Time After Myocardial ...  -  ‎Nov 12, 2009‎
Methods: This was a post-hoc analysis of a randomized clinical trial of valsartan versus captopril in 11256 patients (mean age 65 years) with an acute MI ... Cardiosource

The Deadly Mamba as a Lifesaver  -  ‎Oct 19, 2009‎
...the blood pressure drug captopril from the venom of a pit viper; warfarin, the widely used blood thinner, was derived from moldy sweet clover. ... Wall Street Journal

Dr. John Burnett Found Mambo Snake Venom Treats Heart Failure  -  ‎Oct 20, 2009‎
Aspirin stems from willow tree bark, blood thinner Warfarin comes from sweet clovers, Captopril used for blood pressure comes from venom of a viper and now ... Vitals Spotlight

High Blood Pressure Medicines Show Promise For Treating Heart Disease  -  ‎Oct 19, 2009‎
Captopril (sold as Capoten), the first ACE inhibitor to be taken orally, has been commonly available in the United States since the early 1980s. ... Reuters

DOH opens more BnBs in Caraga region  -  ‎Oct 26, 2009‎
BnB sells low-priced generic over-the-counter drugs and six selected prescription drugs namely Captopril, Metoprolol, Metformin, Glibenclamide, ... Philippine Information Agency

LE SYNDROME DE GUILLAIN BARRE, risque connu mais rare de la vaccination  -  ‎Nov 13, 2009‎
...le déclenchement du syndrome peut également être lié à la prise de certains médicaments (comme la streptokinase, le danazol, le captopril…). ... santé log

¿Sabías que el veneno de algunas serpientes puede ayudar al corazón?  -  ‎Oct 19, 2009‎
...con el objetivo de usar el poder antihipersentivo de su veneno, tras lo cual crearon la sustancia captopril, que ha ayudado a salvar miles de vidas. El Informador

Empresa abandonada com produtos químicos é interditada  -  ‎Oct 26, 2009‎
Também havia medicamentos como Captopril (para pressão alta), Metiformina (para diabetes) e Nimodipine (doenças cardíacas), entre outros. ... Jornal Periscópio

09:47 GAZZETTA UFFICIALE: SOMMARIO (4)  -  ‎Nov 11, 2009‎
Variazione di tipo II all'autorizzazione, secondo procedura di mutuo riconoscimento, del medicinale per uso umano "Captopril Actavis".(ANSA). ANSA Valle d'Aosta

Medicamentos para el tratamiento de la hipertensión arterial se muestran ...  -  ‎Oct 20, 2009‎
El Captopril (nombre comercial Capoten), el primer IECA de administración oral, ha estado ampliamente disponible en Estados Unidos desde comienzos de los ... PR Newswire (Comunicado de prensa)

Warning on child heart drug doses  -  Mar 15, 2007
The amount and formulation of captopril vary widely across the UK when it is ... The survey results showed that only four pharmacies dispensed captopril ... BBC News

… Light Chain Phosphorylation in the Captopril Effects in Spontaneous...  -  Oct 9, 2007
Background: Early treatment with captopril prevents the development of ... Results: At 12 weeks, captopril significantly decreased systolic blood pressure ... Nature.com

Quantitative estimation of renal blood flow by power Doppler …  -  Feb 18, 2005
Captopril was infused intravenously at a rate of 0.2 mg/kg/min after bolus injection (2 ... The infusion of captopril significantly reduced MABP Figure 2, ... Nature.com

Poisonous Tree Frog Could Bring Wealth to Tribe in Brazilian Amazon  -  May 30, 2006
The pharmaceutical giant Squibb used the snake's venom to develop captopril, a blood pressure medicine it began selling in 1975. ... New York Times

Scleroderma - Overview - NY Times Health  -  Sep 6, 2008
A: One of the first major turning points was the introduction of a medicine called captopril. It was a new antihypertensive that had a new mode of action, ... New York Times

Turning Points in Scleroderma Care  -  Sep 11, 2008
A. One of the first major turning points was the introduction of a medicine called captopril. It was a new antihypertensive that had a new mode of action, ... New York Times

Vincent Sauzeau, María A Sevilla, Juan V Rivas-Elena, Enrique de...  -  Jun 11, 2006
...(d–f) Effect of captopril on the plasma levels of AngII (n = 5–7; d), ... +, captopril-treated mice. (g) Histological sections of aortas (top) and hearts ... Nature.com

Zimbabwe: Government to Receive $50,000 Worth of Medical Assistance  -  Oct 5, 2006
The medical assistance includes a variety of drugs, namely Amitryptylline (600 boxes), Atenolol (320 boxes), Captopril (450 boxes), Glibenclamide (310 ... AllAfrica.com

Captopril may limit radiation kidney damage in bone marrow transplant...  -  Nov 15, 2007
Researchers at the Medical College of Wisconsin in Milwaukee have found that the risk of radiation injury in normal tissue after exposure may be reduced by ... News-Medical.net

Cardiovascular Research; Captopril can restore diurnal BP rhythm in …  -  Nov 1, 2005
2005 NOV 1 - (NewsRx.com) -- Captopril administered at night restores the diurnal blood pressure rhythm in adequately controlled, nondipping hypertensives. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Sodium appetite during captopril blockade of endogenous angiotensin...  -  Feb 1, 2008
Angiotensin II and aldosterone increase in response to sodium deficiency to promote sodium and water conservation. In addition, they may act synergistically ... AJP-Regul Integr Comp Physiology...

Captopril enhances renal responsiveness to ANF in dogs with …  -  Jan 1, 2006
The systemic hemodynamic, hormonal, and renal effects of chronic angiotensin-converting enzyme inhibition (CEI) with captopril and the responses to ... AJP-Regul Integr Comp Physiology...

Angiotensin-converting Enzyme (ACE) Inhibitors and Hydrochlorothiazide...  -  Jul 28, 2005
...(Captopril) -- Studies in rabbits and rats at doses up to 400 times the ... Also, captopril has caused deformed skulls in the offspring of rabbits given ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Captopril - Captopril - Medical Drug  -  Jul 6, 2006
Hypertension: Captopril is effective as a singleragent or in combination with other antihypertensive agents such as thiazide-type diuretics. ... Virtual Medical Centre - The Virtual Medical Centre

Wide UK Variation In Use Of Adult Heart Drug Given To Children  -  Mar 17, 2007
But there are no such data available for captopril in children. "The present lack of consistency in liquid captopril formulations dispensed to children with ... Medical News Today - Medical News Today (press release)

… Orthoiodohippurate and Diethylenetriaminepentaacetic Acid Captopril...  -  Feb 1, 2008
Captopril renography (CR) has been established in the past 10 yr as a useful diagnostic test for renovascular hypertension. However, direct comparison of ... Journal of Nuclear Medicine (subscriptio...

Cancer Therapy; Studies add new findings to cancer therapy body of …  -  Apr 11, 2005
Study 2: Plasminogen activator and captopril combine to eliminate melanoma growth. ... Captopril alone reduced tumor growth by about 60%, whereas treatment ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

… ; Nicotine-induced endothelial dysfunction is prevented by captopril...  -  Oct 24, 2006
..."The protective effects of captopril were tested by exposing isolated ... Co-culture of segments of mesenteric artery with captopril (0.03 or 0.1 mM) ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Cancer Therapy; Studies add new findings to cancer therapy body of …  -  Apr 16, 2005
Study 2: Plasminogen activator and captopril combine to eliminate melanoma growth. ... Captopril alone reduced tumor growth by about 60%, whereas treatment ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Endocrinology; 17beta-estradiol enhances captopril hypotensive effect...  -  Aug 29, 2006
2006 AUG 29 - (NewsRx.com) -- 17beta-oestradiol enhances the acute hypotensive effect of captopril in female ovariectomized spontaneously hypertensive rats. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Cancer Therapy; Studies add new findings to cancer therapy body of …  -  Apr 15, 2005
Study 2: Plasminogen activator and captopril combine to eliminate melanoma growth. ... Captopril alone reduced tumor growth by about 60%, whereas treatment ... Pay-Per-View - Angiogenesis Weekly - Factiva, from Dow Jones

… of endotoxin-induced neutrophil alveolitis by captopril and by...  -  Nov 15, 2006
Captopril pretreatment also increased the chemotactic activity of bronchoalveolar lavage fluid (BALF). There was no concomitant alteration in the ... Journal of Leukocyte Biology (subscripti...

Wockhardt to launch hypertension drug in US  -  Sep 17, 2007
..."Wockhardt is gaining a very strong position in several other cardiovascular products, like Enalapril and Captopril. With Amlodipine, company will reinforce ... Daily News & Analysis

Diovan(R) receives EU approval for the treatment of heart attack...  -  May 9, 2005
VALIANT demonstrated that Diovan preserved the benefit of captopril, ... Valsartan, captopril, or both in myocardial infarction complicated by heart failure ... Medical News Today - Medical News Today (press release)

International Approvals: Diovan, Velcade, Macugen  -  May 16, 2005
Furthermore, the addition of captopril to valsartan therapy did not increase efficacy and was associated with an increased rate of adverse events. ... Medscape

Abstract and Introduction  -  Sep 13, 2005
Valsartan, captopril, or both in myocardial infarction complicated by heart failure ... Effect of captopril on mortality and morbidity in patients with left ... Medscape

… radiation injury may be reduced by Long-term administration of...  -  Nov 24, 2007
It suggests that long-term administration of the drug captopril, ... In a double-blind placebo-controlled trial, the team tested captopril on 52 adults and ... TopCancerNews.com

Diabetic Nephropathy; Endopeptidase inhibition reduces proteinuria in...  -  Mar 15, 2005
No side effects were observed with SLV306 and captopril treatment. ... The captopril-treated diabetic rats showed a strong trend towards reduced albumin ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Coughing fits stumping doctors  -  Feb 8, 2006
I thought maybe it was one of her drugs, such as Captopril, but then it seems like she would cough all the time, but she does not. ... $3.50 - Intelligencer, The - NewsBank

Competitors by Product Report  -  Mar 29, 2008
Benazepril Hydrochloride; Captopril; Enalapril Maleate; Lisinopril ... Captopril/Hydrochlorothiazide; Enalapril Maleate/Hydrochlorothiazide ... $75.00 - Revere Reports - Revere

Diabetic Nephropathy; Endopeptidase inhibition reduces proteinuria in...  -  Mar 18, 2005
No side effects were observed with SLV306 and captopril treatment. ... The captopril-treated diabetic rats showed a strong trend towards reduced albumin ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Proibida a venda do remédio Captomax-Captopril 25 mg  -  Nov 12, 2007
RIO - A Secretaria estadual de Saúde e Defesa Civil determinou a interdição cautelar, a suspensão de venda, distribuição, receita e uso do medicamento ... O Globo

Rosella, Halau Hipertensi Sekuat Captopril  -  Apr 22, 2008
MENURUT data dari National Heart, Lung and Blood Association, hampir sepertiga warga negara Amerika menderita hipertensi. Hipertensi terjadi seperti sebuah ... KOMPAS.com

Abstract and Introduction  -  Aug 23, 2005
We compared effects of losartan to captopril on mortality, morbidity, ... ELITE II showed that losartan was not superior to captopril in improving survival ... Medscape

Lack of efficacy of quinapril on vascular damage in limited cutaneous...  -  Dec 21, 2007
Treatment with the ACEI captopril resulted in a rapid normalization of systemic ... 9 The decrease in pulmonary artery pressure seen with captopril seems at ... Nature.com

A bitter pill: Medicines can alter sense of taste  -  Dec 2, 2008
The ACE inhibitor captopril (Capoten) is in this group. Captopril generates more complaints about changes in taste than any other ACE inhibitor. ... Pay-Per-View - Orlando Sentinel - ProQuest Archiver

Medical College of Wisconsin Study Finds Common Drug May Limit …  -  Nov 13, 2007
It suggests that long-term administration of the drug captopril, ... In a double-blind placebo-controlled trial, the team tested captopril on 52 adults and ... Free with registration - Ascribe Higher Education News Service - AccessMyLibrary.com

:: Pernambuco.com :: Últimas, diversão, comunidade, tecnologia,...  -  Apr 15, 2008
Entre os medicamentos à venda estão remédios como sinvastatina (redutor de colesterol), omeprazol (contra gastrite) e captopril (para tratamento de doenças ... Diário de Pernambuco

FibroGen Reports Combinations of FG-3019 Plus ACEi and FG-3019 Plus …  -  Jun 12, 2006
After six weeks of treatment with IgG (control antibody) or captopril, ... In addition, combinations of FG-3019 with captopril or losartan were better than ... Free with registration - Business Wire - AccessMyLibrary.com

Are oral contraceptives associated with increased renin–angiotensin …  -  Aug 24, 2005
The endpoints were change in renal plasma flow (RPF) following captopril ... In nondiabetic women, a significant increase in RPF after captopril ingestion ... Nature.com

Drug May Limit Radiation Kidney Damage In Bone Marrow …  -  Nov 19, 2007
It suggests that long-term administration of the drug captopril, ... In a double-blind placebo-controlled trial, the team tested captopril on 52 adults and ... sciencedaily.com

Em São Paulo, cartela de remédio muda para evitar intoxicação  -  Aug 13, 2008
...rosa; Glibencamida 5 mg (diabetes), lilás; Hidrocloritiazida 25 mg (hipertensão), verde; Captopril (pressão alta), cor do alumínio. ... Último Segundo

Farmácia Popular chega a 420 unidades  -  Feb 21, 2008
...nas farmácias populares são sinvastatina (redutor de colesterol), omeprazol (contra gastrite), captopril (para tratamento de doenças cardiovasculares). ... JB Online

Morirán muchos pacientes del IMSS por falta de recursos para atenderlo...  -  Jan 17, 2006
El dirigente mostró documentos en los que se informa que en diversas clínicas de la periferia queda fuera del cuadro básico el medicamento Captopril, ... La Jornada - La Jornada (México)

Anvisa interdita lote do Captropil  -  Aug 29, 2008
A Agência Nacional de Vigilância Sanitária (Anvisa) interditou cauterlamente nesta sexta-feira, dia 29, do lote 0512003 do medicamento Captopril 25 ... A Tarde On Line

Grand Rounds at the British Hypertension Society: renal artery...  -  May 30, 2007
Mercaptoacetyltriglycine (MAG 3 ) scan with captopril challenge revealed normal bilateral ... 11 This principle is used in the captopril nuclear renogram. ... Nature.com

Clinical Trials; Atherosclerotic events are reduced as effectively by...  -  Apr 12, 2006
..."We compared the effects of captopril, valsartan, and their combination on atherosclerotic events in 14703 patients randomized in the Valsartan in Acute ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Le captopril n'est pas plus efficace qu'un traitement antihypertenseur...  -  Nov 25, 2006
Hansson L, Lindholm LH, Niskanen L. et al., for the Captopril Prevention Project (CAPPP) study group. Effect of angiotensin-converting-enzyme inhibition ... EBM Journal (Abonnement)

Blindan a 191 fármacos contra alza de precios .  -  Dec 9, 2005
...morfina, paracetamol, penicilina, suero antialacrán, captopril, diazepam, diclofenaco, así como las vacunas para influenza, sabin, tétanos, entre otras. ... El Universal - El Universal (México)

Competitors by Product Report  -  Apr 5, 2008
Eon Labs Enalapril Maleate; Sandoz Captopril; Sandoz Enalapril Maleate; Sandoz Fosinopril ... Eon Labs Lisinopril; Sandoz Captopril; Sandoz Lisinopril ... $75.00 - Revere Reports - Revere

Is a Rare Cognitive Side Effect Worth Keeping in Mind?  -  Dec 31, 2006
The first member of the class, captopril, became commercially available in ... Captopril was found to block enkephalinase, the CNS enzyme that breaks down ... Psychiatric Times

André Bernardo e Flávia Salme  -  Oct 3, 2007
Os remédios mais procurados são Captopril, Propranolol e Sinvastatina, todos para hipertensão�, afirma o presidente do Instituto Vital Brazil, ... O Dia Online

Angiotensin-converting Enzyme (ACE) Inhibitors (Systemic).  -  Jul 28, 2005
Antihypertensive Benazepril Captopril Cilazapril Enalapril Enalaprilat Fosinopril ... Lisinopril, captopril, ramipril, and trandolapril are used in some ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Emilio: el coma de Miguel Angel, por la contaminación del río Santiago  -  Feb 8, 2008
...–Están administrándole hasta captopril, porque tuvo hipertensión; lo ayudan con ... –¿Además de los quelantes contra metales pesados, solamente captopril? ... La Jornada Jalisco

New data on post-MI benefits of valsartan  -  Sep 7, 2005
A new analysis of the VALIANT (VALsartan In Acute myocardial iNfarcTion) megatrial confirmed that Diovan is as effective as the ACE inhibitor captopril, ... RxPG NEWS

Atherosclerotic renal artery stenosis and reconstruction  -  Sep 20, 2006
Meanwhile several non-invasive tests, such as captopril test, ... Captopril scintigraphy and captopril test were less accurate than color duplex sonography ... Nature.com

Município é credenciado para ter Farmácia Popular  -  Sep 1, 2007
É o caso do Captopril, utilizado no tratamento de hipertensos. A caixa com 30 comprimidos de marca custa R$ 37,68, a de genéricos custa R$ 14,97, ... Jornal Cidade - Rio Claro

Diazepan efficace quanto captopril in crisi ipertensive  -  Oct 24, 2005
La somministrazione di 5 mg per os di diazepan è efficace quanto il captopril nelle crisi ipertensive senza danno d'organo. In questo studio, randomizzato, ... Pillole.org

BUSQUE EN LAS NOTICIAS DE SALUD  -  Jun 5, 2008
..."Sin embargo, el uso de enalapril o captopril se vinculó con una mayor moralidad, comparado con el ramipril", señalaron los investigadores en Canadian ... Buena Salud

National Inventors Hall of Fame Announces 2007 Inductees.  -  Feb 8, 2007
David Cushman (1939-2000) and Miguel Ondetti (1930-2004) Captopril By ... Captopril was the first of a new class of drugs called ACE inhibitors. ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

Article: Hibiscus tea for hypertension.(Literature Review & Commentary...  -  Feb 1, 2005
The mean reductions in systolic and diastolic BP in the captopril group ... Keywords: Hibiscus sabdariffa; Malvaceae; Captopril; Essential ... al., 1996). ... Pay-Per-View - Townsend Letter for Doctors and Patients - HighBeam Research

胃藥交互作用知多少?  -  Nov 19, 2008
...�血壓藥物如captopril�乙型交感神經阻斷劑(beta blockers)�抗�血藥物如阿�匹 �(aspirin)�ticlopidine等藥與制酸劑併�,除了減少療效,更擔心會有�後�佳� ... udn.com

Noticias de Cuba / El Nuevo Herald - Prensa Internacional / CubaNet …  -  Feb 13, 2006
...enviado por el gobierno cubano cuenta con 102 medicamentos, desde un diurético muy eficaz como la Hidroclorotiazida hasta el antihipertensivo Captopril. ... Cubanet - Cubanet

Sobre el poeta y prisionero de conciencia Ricardo González Alfonso  -  Jun 27, 2008
Por otra parte Ricardo padece de Hipertensión Arterial y el cardiologo le subió la dosis del Captopril (de una a dos tabletas diarias). ... Cuba Nuestra

Noticiário Executivo - DOE/PE 10/06/08  -  Jun 10, 2008
...como no caso do anti-hipertensivo Captopril, comercializado em outras farmácias por cerca de R$ 18, enquanto no Lafepe o envelope com 30 comprimidos de ... pe.gov.br

Tubarão. Um “santo remédioâ€? para quem não pode pagar pelos …  -  Sep 9, 2005
Só de Captopril, comprimido para quem tem problema de pressão alta, a prefeitura adquiriu este ano 1,8 milhão de unidades. Para assegurar que os produtos ... adjorisc.com.br

Programa não tem como se sustentar  -  Apr 12, 2006
O Captopril, usado para combater a hipertensão, por exemplo, custou na última licitação do governo R$ 0,02 por unidade. Agora, no reembolso que o ministério ... bonde.com.br

Bénéfices et limites des traitements pharmacologiques  -  May 12, 2006
Dans une étude limitée à 22 patients présentant une urgence hypertensive, le captopril sublingual 25 mg a montré une efficacité comparable à celle de la ... EBM Journal (Abonnement)

Revue : l'angioscanner et l'IRM sont les examens diagnostiques non …  -  Dec 2, 2005
L'échographie (p = 0,01) et la scintigraphie au captopril (p = 0017) ont été supérieures au test ... Le test au captopril est l'examen le moins performant. ... EBM Journal (Abonnement)

Revue : l'angioscanner et l'IRM sont les examens diagnostiquesnon …  -  Nov 28, 2005
L'échographie (p = 0,01) et la scintigraphie au captopril (p = 0017) ont été supérieures au test ... Le test au captopril est l'examen le moins performant. ... EBM Journal (Abonnement)

Warner-Lambert Co. v. Teva Pharmaceuticals USA, Inc., 418 F.3d 1326, ...  -  Aug 11, 2005
It was developed using the ACE inhibitor known as captopril. The drug was expensive, however, and exhibited adverse side effects. ... $2.95 - U.S. Court of Appeals, Federal Circuit - VersusLaw

Physiology; Data advance knowledge in physiology research  -  Mar 28, 2005
Study 3: A high-salt diet and/or chronic captopril treatment lowers exercise ... "Rats were placed on normal rat chow, normal rat chow with captopril (100 ... Pay-Per-View - Proteomics Weekly - Factiva, from Dow Jones

Physiology; Data advance knowledge in physiology research  -  Mar 29, 2005
Study 3: A high-salt diet and/or chronic captopril treatment lowers exercise ... "Rats were placed on normal rat chow, normal rat chow with captopril (100 ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Proteinuria linked to MI deaths.(Cardiovascular Medicine)  -  Dec 1, 2005
The analysis also examined the impact of the ACE inhibitor treatment used in the study, a regimen of 50 mg captopril tid, which was compared with placebo. ... Pay-Per-View - Internal Medicine News - Factiva, from Dow Jones

Neurology; Recent studies from Medical College of Wisconsin, US, add ...  -  Dec 5, 2006
A furosemide + captopril 14-day treatment group was added to control for the blood pressure change (96±3 mmHg)." Scientists said, "microvessel density ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Researchers have identified genetic markers that can predict the risk...  -  May 23, 2007
Blood pressure reduction with captopril was also significantly lower in women with the ACE2 gene. Further work is continuing to ascertain the association of ... Nature.com

Antihypertensive and Renal Protective Effects of Renin-Angiotensin …  -  Apr 12, 2006
Treatment with losartan, captopril, and the TRx prevented the rhEPO-induced increased in systolic BP. The TRx was less effective in preventing histologic ... Nature.com

The benefits of renin–angiotensin blockade in hypertension are …  -  Mar 22, 2006
To illustrate the above point, a substudy published after the landmark trial of captopril in diabetic nephropathy conducted by the Collaborative Study Group ... Nature.com

Abstract and Introduction  -  Aug 2, 2007
Following captopril and losartan, which were respectively the first ACE inhibitor ... In contrast with captopril and enalapril, imidapril has a prolonged ... Medscape

Hibiscus tea for hypertension.(Literature Review & Commentary)  -  Feb 1, 2005
The mean reductions in systolic and diastolic BP in the captopril group were slightly, but not significantly, greater than the reductions in the hibiscus ... Free with registration - Townsend Letter for Doctors and Patients - AccessMyLibrary.com

Recurrent acute pancreatitis probably secondary to lisinopril.(Case …  -  Dec 1, 2006
The offending agents have included captopril, enalapril, quinapril, ramipril, perindopril and lisinopril. ... Acute pancreatitis due to captopril treatment. ... Free with registration - Southern Medical Journal - AccessMyLibrary.com

{beta}-Blockers for hypertension -- Carlberg 176 (7): 971 -- Canadian...  -  Mar 27, 2007
Second, we excluded the results of the Captopril Prevention Project (CAPPP) trial, 3 because it is impossible to retrieve data on how many patients in that ... CMAJ

Erie Times-News : Front Page<br>  -  Oct 27, 2006
Capoten Captopril 100mg tab. Capoten Captopril 12.5mg tab. Capoten Captopril 25mg tab. Capoten Captopril 50mg tab. Tegretol Carbamazepine 100mg ctb ... $2.95 - Erie Times-News - NewsBank

Diabetic Nephropathy; Researchers describe findings in diabetic …  -  Apr 25, 2005
No side effects were observed with SLV306 and captopril treatment. ... The captopril-treated diabetic rats showed a strong trend towards reduced albumin ... Pay-Per-View - Obesity & Diabetes Week - Factiva, from Dow Jones

Pancreatic Fibrosis; Angiotensin II contributes to development of...  -  Feb 8, 2005
Subgroups daily received captopril (60 mg/kg/day), ... They concluded, "These increases were blunted significantly by captopril or losartan treatment. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Article: Aggressive secondary prevention urged in CHD.(Cardiovascular...  -  Jul 1, 2006
ACE inhibitors were enalapril 10 or 20 mg, captopril 100 ... two years). ACE inhibitors were enalapril 5-40 mg, captopril 75 ... ... Pay-Per-View - Internal Medicine News - HighBeam Research

Article: Heart attack response.(News) - Coventry Evening Telegraph ( …  -  Jul 4, 2008
VALIANT demonstrated that ... benefits of captopril in heart attack patients - and is at least ... Journal of the National Medical Association ... Pay-Per-View - Coventry Evening Telegraph - HighBeam Research

Press Release: National Inventors Hall of Fame Announces 2007 …  -  Feb 8, 2007
David Cushman (1939-2000) and Miguel Ondetti (1930-2004) Captopril By ... Captopril was the first of a new class of drugs called ACE inhibitors. ... Pay-Per-View - PR Newswire - HighBeam Research

Pancreatic Fibrosis; Angiotensin II contributes to development of...  -  Feb 12, 2005
Subgroups daily received captopril (60 mg/kg/day), ... They concluded, "These increases were blunted significantly by captopril or losartan treatment. ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Anvisa barra venda de lotes de medicamento contra hipertensão  -  Oct 24, 2007
O problema detectado é um excesso de captopril dissulfeto, substância que é um dos produtos normais da degradação do captopril ao longo do tempo. ... G1.com.br

1987: Toxin weist Weg zum ersten ACE-Hemmer  -  Mar 21, 2005
Captopril, das von Dr. David Cushman und Dr. Miguel A. Ondetti vom Unternehmen ... Und 1987 wurde Captopril schließlich mit dem von der "Ärzte Zeitung" ... Ärzte Zeitung

,,Plots had ik bloeddruk 20''  -  Mar 18, 2005
Toen mijn huisdokter op mijn vraag het generische Captopril voorschreef, ... Op aanraden van de hartspecialist ben ik meteen gestopt met Captopril en weer ... Het Nieuwsblad

Capozide.(Drug overview)  -  Jan 22, 2007
Captopril, the ACE inhibitor, works by preventing a chemical in your blood called ... Captopril also enhances blood flow throughout your blood vessels. ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Photos by Chris Thompson  -  Jul 1, 2005
How to take it: While on captopril, it would be wise to supplement with 15 mg of zinc daily, the amount included in a typical multivitamin/mineral. ... Delicious Living Magazine

Antianxiety Treatment May Lower Blood Pressure  -  Oct 17, 2005
The researchers randomly assigned 19 subjects to 5 mg oral diazepam and 17 subjects to 25 mg sublingual captopril. The researchers monitored BP and heart ... RedOrbit

Hospital short of heart tablets  -  Jun 7, 2007
Patients will be given Captopril which is of the same group as Enalapril. ... Ironically, he said now Enalapril is out of stock and Captopril is available. ... www.gov.bw

Diovan® receives EU approval for the treatment of heart attack...  -  May 10, 2005
VALIANT demonstrated that Diovan preserved the benefit of captopril, ... Valsartan, captopril, or both in myocardial infarction complicated by heart failure ... i-newswire.com

A Publication of BMJ Publishing Group  -  Dec 1, 2005
Captopril. One RCT that included persons with type 1 diabetes and late nephropathy found that, compared with placebo, captopril (an ACE inhibitor) reduced ... AAFP News Now

Article: Easy, refreshing and no oven time - The Topeka Capital...  -  Jun 28, 2006
Medical research indicates that hibiscus tea may be effective in the treatment ... study, participants took either the hibiscus tea or captopril daily for 4 ... Pay-Per-View - Topeka Capital-Journal - HighBeam Research

Pollutant particles produce vasoconstriction and enhance MAPK …  -  Aug 1, 2005
The UP-induced activation of ERK1/2 and p38 was attenuated by captopril, ... Effects of captopril on UP-induced ERK1/2 and p38 phosphorylation. ... $4.95 - Environmental Health Perspectives - ECNext

Brand Names/Synonyms:
Captopril is also known by the following brand names and/or synonymsAcediur; Aceplus; Acepress; Acepril; Alopresin; Apopril; Capoten; Capozide; Captolane; Captopril; Captopril [Usan:Ban:Inn:Jan]; Captoprilum [Inn-Latin]; Captopryl; Captoril; Cesplon; Dilabar; Garranil; HSDB 6527; Hipertil; Hypertil; L-Captopril; Lopirin; Lopirin [Switzerland]; Lopril; SA 333; Tenosbon; Tensobon; Tensoprel

Drug Category:
Captopril is categorized under the following by the FDA: Antihypertensive Agents; Angiotensin-converting Enzyme Inhibitors; ATC:C09AA01

Dosage Forms:
in potencies of 12.5, 25, 50, 100mg as scored tablets

Absorption:
75% without food

Interactions:
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Chemical IUPAC Name:
1-(2-methyl-3-sulfanyl-propanoyl)pyrrolidine-2-carboxylicacid





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