Cartia XT

This page contains recent news articles, when available, and an overview of Cartia XT but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Cartia XT
(when available)

Pharmacology and use:
Diltiazem, a benzothiazepine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Diltiazem is similar to other peripheral vasodilators. Diltiazem inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload. For the treatment of Hypertension

Mechanism Of Action:
Possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum, dilitiazem, like verapamil, inhibits the influx of extracellular calcium across both the myocardial and vascular smooth muscle cell membranes. The resultant inhibition of the contractile processes of the myocardial smooth muscle cells leads to dilation of the coronary and systemic arteries and improved oxygen delivery to the myocardial tissue.

News Articles on Diltiazem

Company Profile Report  -  Sep 30, 2006
Andrx Pharmaceuticals Diltia XT (Diltiazem HCl Extended-Release); Andrx Pharmaceuticals Taztia (Diltiazem HCl); Andrx Pharmaceuticals Cartia XT (Diltiazem ... $50.00 - Revere Reports - Revere

Competitors by Product Report  -  Aug 2, 2008
Amlodipine Besylate; Andrx Pharmaceuticals Cartia XT (Diltiazem HCl Extended-Release); Andrx Pharmaceuticals Diltia XT (Diltiazem HCl Extended-Release) ... $75.00 - Revere Reports - Revere

Competitors by Product Report  -  Aug 2, 2008
Amlodipine Besylate; Andrx Pharmaceuticals Cartia XT (Diltiazem HCl Extended-Release); Andrx Pharmaceuticals Diltia XT (Diltiazem HCl Extended-Release) ... $75.00 - Revere - Alacra Store

Drug/Medical Device  -  Sep 30, 2006
Andrx Pharmaceuticals Cartia XT (Diltiazem HCl Extended-Release), Chronic Stable Angina, Hypertension, Headache, Dizziness, Bradycardia, ... $70.00 - Revere Reports - Revere

United States top 250 generic drugs by retail sales and manufacturer...  -  Apr 23, 2007
HCI $70112673.08 Andrx Cartia XT $70072533.55 Watson Labs Hydrocodone w/APAP $70023433.78 Mallinckrodt Oxycodone $68467927.46 HCI-acetaminophen Mylan ... $20.00 - Chain Drug Review - Alacra Store

Generics makers keep new products coming.(RX/GENERICS)(Statistical …  -  Sep 17, 2007
00172433160 96 Watson Labs Cartia XT 62037059990 97 Teva USA Amlodipine ... ... Cartia XT 201004636 58 Teva USA Budeprion SR ... 815403 97 Teva USA Naproxen ... Pay-Per-View - Chain Drug Review - HighBeam Research

Global top 300 multisource generic pharmaceuticals by sales, …  -  Apr 28, 2008
Metformin HCI 00172433160 96 Watson Labs Cartia XT 62037059990 97 Teva ... Simvastatin 65862005299 198 Watson Labs Cartia XT 62037059890 199 Global Pharm. ... $20.00 - Chain Drug Review - Alacra Store

Top 300 multisource generics by manufacturer and NDC11 number.(RX/ …  -  Apr 28, 2008
Metformin HCI 00172433160 96 Watson Labs Cartia XT 62037059990 97 Teva ... Simvastatin65862005299 198Watson Labs Cartia XT 62037059890 199Global Pharm. ... Pay-Per-View - Chain Drug Review - HighBeam Research

SHAREHOLDER VOTE ON SALE SCHEDULED FOR JUNE 28  -  May 19, 2006
...recall or reduction in manufacturing or distribution of four key Andrx products -- heart drugs Cartia XT and Taztia XT, cholesterol drug Altoprev or ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

ANDRX REPORTS HIGHER EARNINGS  -  Mar 10, 2005
...several additional counties in New York state have sued the company for allegedly overcharging Medicaid in regard to its Cartia XT and metformin drugs. ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

Article: Cox files charges accusing provider of false Medicaid...  -  Jul 19, 2005
Andrx launched Cartia XT, the first generic equivalent of Cardizem CD. By August, Cardizem CD lost 46 percent of new prescriptions written by primary care . ... Pay-Per-View - Detroit Free Press - HighBeam Research

Generics makers keep new products coming.(RX/GENERICS)(Statistical …  -  Sep 17, 2007
Amox TR-Potassium Clavulanate $198018118.31 Watson Labs Cartia xt $193614325.46 Barr Fentanyl Citrate $193389905.90 Teva USA Budeprion sr $190606160.83 Teva ... Free with registration - Chain Drug Review - AccessMyLibrary.com

Competitors by Product Report  -  Dec 16, 2006
Andrx Pharmaceuticals Cartia XT (Diltiazem HCl Extended-Release); Andrx Pharmaceuticals Diltia XT (Diltiazem HCl Extended-Release); Andrx Pharmaceuticals ... $75.00 - Revere Reports - Revere

Heart drug users owed refund  -  Jul 20, 2005
Refunds will be mailed to people who paid all or part of the purchase price for Cardizem CD or its generic versions - Cartia XT, diltiazem CD or diltiazem ... $3.50 - Bucks County Courier Times - NewsBank

Pharmaceutical Executive  -  Apr 1, 2007
Another example is Andrx's launch of Cartia XT, or generic Cardizem CD. According to In Vivo's Wendy Diller, for six months, Andrx had no competition, ... PharmExec.com

Competitors by Product Report  -  Sep 30, 2006
Andrx Pharmaceuticals Diltia XT (Diltiazem HCl Extended-Release); Andrx Pharmaceuticals Taztia (Diltiazem HCl); Andrx Pharmaceuticals Cartia XT (Diltiazem ... $75.00 - Revere Reports - Revere

Kansas Regulations - 129-5-1. Prior authorization.  -  Nov 3, 2005
...(18) calcium channel blockers: (A) Diltiazem extended release, with the following brand names: (i) Cardizen SR® (ii) Cardizem CD® (iii) Cartia XT® (iv) ... Pay-Per-View - Kansas Regulations - Loislaw

Andrx Corporation Reports Financial Results for 2006 Second Quarter.  -  Aug 8, 2006
In our generic products business, although revenues continue to be affected by no launches, Cartia XT(R) and Taztia XT(R) have not been impacted by ... $4.95 - Business Wire - ECNext

United States top 250 generic pharmaceuticals by sales, and …  -  Feb 4, 2008
Cartia XT 201004636 58 Teva USA Budeprion SR 198969509 59 Sandoz Metoprolol succinate 198917253 60 Lupin Lisinopril 191626950 61 Barr Tri-sprintec 186051403 ... $20.00 - Chain Drug Review - Alacra Store

United States top 200 generic pharmaceuticals by retail sales in...  -  Feb 19, 2007
...-5.7 54 Enalapril 192256 -3.3 55 Verapamil SR 185361 -9.7 56 Ibuprofen 182898 -6.7 57 Cartia XT 181209 5.8 58 Glipizide ER 168180 -13.6 59 Acetaminophen ... $20.00 - Drug Topics - Alacra Store

Press Release: Maryland and other states distribute $24 million in …  -  Jul 19, 2005
Andrx launched Cartia XT, the first generic equivalent of Cardizem CD. By August, Cardizem CD lost 46 percent of new prescriptions written by primary care . ... Pay-Per-View - M2 Presswire - HighBeam Research

Finance; Andrx reports distributed products revenue increased 11.5%  -  Sep 5, 2006
In our generic products business, although revenues continue to be affected by no launches, Cartia XT and Taztia XT have not been impacted by additional ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Article: Top 250 multisource generics by manufacturer.(RX RETAIL …  -  Feb 4, 2008
53489037001 89 Teva USA Cephalexin 00093314701 90 Watson Labs Hydrocodone ... 00172433160 96 Watson Labs Cartia XT 62037059990 97 Teva USA Amlodipine ... ... Pay-Per-View - Chain Drug Review - HighBeam Research

Top 200 generic drugs by units in 2006.(COMMUNITY PRACTICE)( …  -  Mar 5, 2007
34.6 91 Promethazine/Codeine 4264 -13.2 92 Buspirone HCl 4201 3.6 93 Methotrexate 4188 5.5 94 Bupropion SR 4164 10.6 95 Cartia XT 4071 10.9 96 Terazosin ... $4.95 - Drug Topics - ECNext

Global top 200 generic drugs by retail sales in dollars and percent …  -  Feb 21, 2005
Tartrate 192975 -4.8 43 Isosorbide Mononitrt 191358 -11.6 44 Glybrid/Metfrmin HCl 190564 NA 45 Cartia XT 187929 -4.6 46 Acetaminophen w/Cod 184115 -10.1 ... $20.00 - Drug Topics - Alacra Store

Article: Top 250 multisource generics.(RX/GENERIC DRUGS)(Statistical ...  -  Apr 23, 2007
53489037001 89 Teva USA Cephalexin 00093314701 90 Watson Labs Hydrocodone ... 00172433160 96 Watson Labs Cartia XT 62037059990 97 Teva USA Amlodipine ... ... Pay-Per-View - Chain Drug Review - HighBeam Research

United States top 200 generic drugs by retail sales in dollars for...  -  Feb 28, 2005
191358 44 Glybrid/metformin HCl 190564 45 Cartia XT 187929 46 Acetaminophen w/codeine 184115 47 Glyburide 181720 48 Ibuprofen 181402 49 Albuterol nebulizer ... $20.00 - Chain Drug Review - Alacra Store

Article: Top 190 multisource generics by manufacturer and NDC11 …  -  Sep 29, 2008
53489037001 89 Teva USA Cephalexin 00093314701 90 Watson Labs Hydrocodone ... 00172433160 96 Watson Labs Cartia XT 62037059990 97 Teva USA Amlodipine ... ... Pay-Per-View - Chain Drug Review - HighBeam Research

Watson Pharmaceuticals to Acquire Andrx | Article from AP Online | …  -  Mar 13, 2006
Cardizem when the generic drugs, such as Andrx's Cartia XT, would have cost about ... investor relations for Weston, Fla.-based Andrx, said the company ... Pay-Per-View - AP Online - HighBeam Research

United States top 200 generic drugs by sales in units for 2004  -  Feb 28, 2005
127 Nitroquick 144375 128 Mirtazapine 143615 129 Ciprofloxacin HCl 142895 130 Cartia XT 139205 131 Quinine sulfate 135401 132 Clotrimazl/betamthsn. ... $20.00 - Chain Drug Review - Alacra Store

Top 200 generic drugs by retail dollars in 2006.(COMMUNITY PRACTICE …  -  Feb 19, 2007
...-5.7 54 Enalapril 192256 -3.3 55 Verapamil SR 185361 -9.7 56 Ibuprofen 182898 -6.7 57 Cartia XT 181209 5.8 58 Glipizide ER 168180 -13.6 59 Acetaminophen ... $4.95 - Drug Topics - ECNext

United States top 200 generic drugs by retail sales in dollars and...  -  Mar 6, 2006
193113 -5.5 52 Mirtazapine 190291 -12.9 53 Ranitidine HCl 174205 -21.8 54 Acetaminophen w/Cod 171909 -6.6 55 Cartia XT 171351 -8.8 56 Fluconazole 168275 ... $20.00 - Drug Topics - Alacra Store

Brand Names/Synonyms:
Cartia XT is also known by the following brand names and/or synonymsAcalix; Anoheal; Adizem; Altiazem; Anginyl; Angizem; Apo-Diltiaz; Britiazim; Bruzem; Calcicard; Cardizem; Cardizem CD; Cardizem SR; Cardizen LA; Cartia XT; Citizem; Cormax; Deltazen; Dilacor; Dilacor-XR; Diladel; Dilcontin; Dilpral; Dilrene; Dilt-cd; Dilta-Hexal; Diltia; Dilticard; Dilzem; Dilzen; Endrydil; Herbesser; Incoril AP; Masdil; Novo-Diltazem; Nu-Diltiaz; Syn-Diltiazem; Tiazac Tildiem; d-cis-Diltiazem

Drug Category:
Cartia XT is categorized under the following by the FDA: Vasodilator Agents; Cardiovascular Agents; Antihypertensive Agents; Calcium-channel blocking agents; ATC:C08DB01

Dosage Forms:
SOLUTION

Absorption:
Diltiazem is well absorbed from the gastrointestinal tract but undergoes substantial hepatic first-pass effect.

Interactions:
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Chemical IUPAC Name:
[2-(2-dimethylaminoethyl)-5-(4-methoxyphenyl)-3-oxo-6-thia-2-azabicyclo[5.4.0]undeca-7,9,11-trien-4-yl]ethanoate





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