Celebrex

This page contains recent news articles, when available, and an overview of Celebrex but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Celebrex
(when available)

Pharmacology and use:
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is classified as a nonsteroidal anti-inflammatory drug (NSAID). Celecoxib is used to treat rheumatoid arthritis, osteoarthritis, and familial adenomatous polyposis (FAP). It is not known if there are any effects of Celecoxib on platelets. For relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis

Mechanism Of Action:
The mechanism of action of Celecoxib is believed to be due to inhibition of prostaglandin synthesis. Unlike most NSAIDs, which inhibit both types of cyclooxygenases (COX-1 and COX-2), Celecoxib is a noncompetitive inhibitor of cyclooxygenase-2 (COX-2) enzyme. It binds with its polar sulfonamide side chain to a hydrophilic side pocket region close to the active COX-2 binding site. Both COX-1 and COX-2 catalyze the conversion of arachidonic acid to prostaglandin (PG) H2, the precursor of PGs and thromboxane.

News Articles on Celecoxib

Celebrex combats skin cancer in vulnerable group  -  05 Jan 2010
Celecoxib, marketed as Celebrex, is a nonsteroidal anti-inflammatory drug. Other NSAIDs — including ibuprofen, aspirin and naproxen — suppress ... Science News

Turmeric (Curcumin) for Inflammatory Conditions  -  05 Jan 2010
Down-regulation of COX-2, which is the enzyme targeted by celecoxib (Celebrex); 2. Inhibition of the production of TNF-alpha, which is the cytokine targeted ... EmpowHer (blog)

Celebrex inhibited the burden of skin cancer in high-risk patients  -  05 Jan 2010
Celecoxib, sold under the brand name of Celebrex by Pfizer Inc., is a non-steroidal anti-inflammatory drug (NSAID). Patients with Gorlin syndrome typically ... Bioscience Technology

Common anti-inflammatory drug could help prevent skin cancers, Stanford ...  -  05 Jan 2010
They wondered if the drug, sold by the pharmaceutical company Pfizer under the brand names Celebrex and Onsenal, would have a similar effect on the more ... ScienceBlog.com (blog)

COX-2-Hemmer könnte Hautkrebs vorbeugen  -  05 Jan 2010
Herz-Kreislauf-Erkrankungen unter dem COX-2-Inhibitor Rofecoxib zutage gefördert hatte (Im Gegensatz zu Vioxx wurde Celebrex nicht vom Markt genommen). ... Deutsches Ärzteblatt

Celebrex Reduces Anti-Clotting Effectiveness of Aspirin  -  ‎Dec 16, 2009‎
A new study has revealed that regular users of the painkiller Celebrex, who also use low-dose aspirin to keep the risk of heart attacks and strokes to a ... TopNews United States

People's Pharmacy: Bing cherries ease hip inflammation  -  ‎Jan 3, 2010‎
These enzymes are targeted by anti-inflammatory drugs such as Celebrex, diclofenac and ibuprofen, so it is not surprising that cherry juice appears to ... Houston Chronicle

Latest Tylenol Recall Adds to Arthritis Patients Woes  -  ‎Dec 29, 2009‎
One of the most commonly used prescription drugs, Celebrex (celecoxib), has remained on the market even though its two cousins, Vioxx and Bextra, ... eMaxHealth

Taking Celebrex May Interfere With Aspirin's Anti-Clotting Effects, New Study Says  -  ‎Dec 18, 2009‎
A new US study suggests taking celecoxib, the arthritis pain drug sold under the brand name Celebrex, may prevent low-dose aspirin from preventing ... Attorney at Law

Anti-inflammatory drugs interfere with aspirin's clotting ability: study  -  ‎Dec 23, 2009‎
23 (Xinhua) -- A new study conducted at Ben-Gurion University (BGU) in Israel reveals that Celebrex and other anti-inflammatory coxib medications may ... Xinhua

People's Pharmacy home remedies: Cherry juice for arthritis, vitamin D for ...  -  ‎Dec 30, 2009‎
These enzymes are targeted by anti-inflammatory drugs like Celebrex, diclofenac and ibuprofen, so it is not surprising that cherry juice appears to ... Seattle Times

Celebrex May Counter Benefits of Low-Dose Aspirin  -  ‎Dec 25, 2009‎
Patients who take aspirin and coxibs together (Celebrex is a coxib) inhibit the ability of aspirin to prevent heart attacks and strokes. ... About - News & Issues (blog)

Quid pro quo  -  ‎Jan 4, 2010‎
Two of the pain relievers—Celebrex and the recalled Bextra—that Reuben published favorable findings on were from Pfizer, which paid him a still undisclosed ... ModernHealthcare.com

Chronic Kidney Disease — More Common Than You Think  -  ‎Jan 2, 2010‎
...including anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil) or celecoxib (Celebrex), as well as acetaminophen and some antibiotics. ... Ethiopian Review

Celecoxib could impede effects of low-dose aspirin  -  ‎Dec 17, 2009‎
Ann Arbor, MI - New laboratory research suggests that the COX-2 inhibitor celecoxib (Celebrex, Pfizer), might impede the action of "baby" aspirin [1]. ... TheHeart.Org

Senate Rejects Bulk Imports of Medicine from Canada, but Personal Importation ...  -  ‎Dec 23, 2009‎
For example, a Canadameds.com search for Celebrex shows both name-brand and generic options and provides the cost comparison of the drug sourced from four ... PR Newswire (press release)

Cox-2 Inhibitor Blunts Aspirin's Cardioprotection  -  ‎Dec 16, 2009‎
The pain killer celecoxib (Celebrex) may interfere with the cardioprotective benefit of low-dose ... MedPage Today

One Nice Spice For Wintertime  -  ‎Dec 15, 2009‎
Studies have shown that ginger root has anti-inflammatory actions, similar to arthritis drugs such as Celebrex, but without the risk of side effects. ... Cape May County Herald

Pfizer extends medication giveaway for jobless  -  ‎Dec 10, 2009‎
Drugs covered in the program include some of Pfizer's top money makers, from cholesterol fighter Lipitor and painkiller Celebrex to fibromyalgia treatment ... The Associated Press

Gov't urged to fund BioChem Informatics Center for drug manufacture  -  ‎Dec 25, 2009‎
...“We came up with a score of new candidates predicted to be more potent than existing compounds in the market like celebrex and celecoxib,� said Billones in ... Manila Bulletin

In re: Vioxx Class Cases  -  ‎Dec 16, 2009‎
The first such COX-2 inhibitor was celecoxib, marketed by Pfizer under the trade name Celebrex. The second COX-2 inhibitor was rofecoxib, which was marketed ... Leagle, Inc.

Scientific mind  -  ‎Dec 28, 2009‎
That research led to the billion-dollar drug Celebrex, which fights both arthritis and colon cancer but lacks some of the drawbacks of treatment regimens ... St.Louis Jewishlight.com

Pfizer general counsel changes all the rules  -  ‎Dec 23, 2009‎
...had been co-head of the mass tort and class action practice at DLA Piper, and was lead trial counsel for Pfizer in its Celebrex and Bextra litigation. ... Daily Report (registration)

This Week In History: Decembe 13-19  -  ‎Dec 12, 2009‎
Pfizer Inc. said it had found an increased risk of heart problems with patients taking Celebrex. One year ago: President-elect Barack Obama named former ... Philadelphia Bulletin

New sport gives Hayer new chance to represent Canada  -  ‎Dec 27, 2009‎
...“I was on Celebrex, Advil, whatever it took to get me on the hill. So I didn't train much, just went from race to race. They said six weeks (to heal) and ... StarPhoenix

Tedavisi en pahalı 10 hastalık  -  ‎Jan 3, 2010‎
Vioxx ve Celebrex gibi pahalı ilaçların ise 2000 yıllarında tedaviye eklenmesiyle masraflar daha da arttı. Vioxx isimli ilaç, 2004 yılında kalp krizi ... Zaman

Pain Meds Can Cause Serious Side Effects  -  ‎Dec 18, 2009‎
Celecoxib (Celebrex), a COX-2 specific NSAID, may also be considered an option for some patients. "The good news is that for people who take NSAIDs, ... Greenwood Today

Ennis & Ennis, PA Announces Nationwide Free Legal Consultations For Users of Paxil  -  ‎Dec 16, 2009‎
Guidant Pacemakers and Defibrillators, Celebrex, Bextra, Stevens Johnson Syndrome related cases, Ortho Evra Birth Control Patch and others. ... Behavioral Health Central (blog)

תרופות ×?נטי-דלקתיות בשילוב ×?ספירין - סיכון להתקף לב  -  ‎Dec 28, 2009‎
...קבוצה חדשה של תרופות נוגדות דלקת, coxibs, הכוללות ×’×? Celebrex ו-Arcoxia, פותחה בעשור ×”×?חרון לטיפול בדלקת פרקי×?, כמו ×’×? בכ×?בי×? ×?חרי×?. ... News1 מחלקה ראשונה

Pfizer financiará un año más los medicamentos de los desempleados en EEUU  -  ‎Dec 10, 2009‎
...meses algún fármaco de la firma, desde Lipitor (colesterol) o Celebrex (artritis) hasta Viagra, y que se haya quedado sin trabajo durante este año. ... EFE

CELEBREX, extension de la prise en charge au traitement de la spondylarthrite ...  -  ‎Dec 23, 2009‎
CELEBREX 100 mg et 200 mg gélules sont désormais remboursables quand ils sont indiqués pour le soulagement des symptômes dans le traitement de la ... Le Généraliste (Abonnement)

'세레브렉스' 병행하면 효과 ↓  -  ‎Dec 16, 2009‎
...[메디컬투ë?°ì?´ ê¹€ë¡?환 기ìž?ï¼½ 저용량 아스피린ì?„ 복용시 세레브렉스(Celebrex)를 병행 복용하면 아스피린ì?˜ 심장마비와 뇌졸중ì?„ 예방하는 효과가 줄어들 수 있는 ... 마이데일리

ПопулÑ?рные препараты от артрита нейтрализуют дейÑ?твие аÑ?пирина  -  ‎Dec 28, 2009‎
Ð?овые препараты из группы кокÑ?ибов, к которым отноÑ?Ñ?Ñ‚Ñ?Ñ? Celebrex и Arcoxia, в поÑ?ледние деÑ?Ñ?тилетие активно иÑ?пользуютÑ?Ñ? длÑ? лечениÑ? артрита и других болей ... NEWSru.co.il

셀레브렉스, 저용량 아스피린 병용 “좋지 않다â€?  -  ‎Dec 20, 2009‎
...주민우 기ìž? [헬스코리아뉴스] 관절염 치료제 '셀레브렉스(Celebrex)'와 저용량 아스피린 병용ì?´ 아스피린 효과를 ê°?소시킨다는 연구결과가 나왔다. ... 헬스코리아뉴스

إبرة الكورتيزون ...علاج سحري لآلام المرÙ?Ù‚ !  -  ‎Jan 2, 2010‎
وعادة ما يتم صرÙ?ها Ù„Ù?ترة تتراوح لمدة اسبوع أو اسبوعين وتأخذ عن طريق الÙ?Ù… ومن الأمثلة عليها عقار (voltari) Ùˆ(Celebrex) Ùˆ(Ù?Rofenac) وغير ذلك وهي كثيرة. ... الرياض

10 Penyakit dengan Biaya Pengobatan Termahal  -  ‎Dec 16, 2009‎
Obat-obatan mahal seperti Vioxx dan Celebrex yang muncul pada awal tahun 2000 menambah mahal biaya penyembuhan penyakit radang sendi ini. ... Detikcom

利润的诱惑制è?¯ä¼?业走å?‘金字塔尖的抗肿瘤  -  ‎Dec 10, 2009‎
...事实上,目å‰?辉瑞公å?¸æ‰€é”€å”®çš„3å?ªé‡?è¦?的抗肿瘤è?¯ç‰©éƒ½æ˜¯æ?¥è‡ªåŽŸå…ˆçš„ç«žäº‰å¯¹æ‰‹æ³•çŽ›è¥¿äºšï¼Œ2003年辉瑞公å?¸ä¸ºäº†èŽ·å¾—å…³èŠ‚ç‚Žè?¯ç‰©è¥¿ä¹?葆(Celebrex)而收购了法玛西亚。 ... 中国高新技术产业导报

Pharmacist indicted on 69 criminal counts  -  14 Nov 2009
...said she discovered claims for such medications as Advair, Celebrex, Lidoderm, and Provental were billed to her insurance company, United Healthcare. ... Sparta Independent

Viagra Maker Hard On St. Louis; Pfizer Announces It Will Slash 600 Local Jobs  -  ‎Nov 10, 2009‎
...​Yesterday, Pfizer (maker of Viagra, Celebrex, Lipitor and countless other drugs whose advertisements pay for the network evening news) announced that it ... Riverfront Times

Pfizer sanctioned in BYU lawsuit  -  ‎Oct 28, 2009‎
...that Pfizer had engaged in repeated delays in a lawsuit involving billions of dollars earned from the highly successful anti-inflammatory drug Celebrex. ... Salt Lake Tribune

Online Pharmacy - celebrex  -  ‎Oct 31, 2009‎
Before using Celebrex. I took Celebrex should have linked celecoxib at doses without a doctor's prescription. In practice. Patients with this form where you ... Newstalk ZB

Correction: Reading Pfizer's Pulse - Q3 Earnings Preview  -  ‎Oct 20, 2009‎
It would also help offset dwindling sales of Celebrex, which has been impacted severely following the recall of the similar-acting Vioxx. ... RTT News

What NSAIDs Do to Your Kidneys  -  ‎Oct 26, 2009‎
Currently, the only COX-2 inhibitor available in the United States is Celebrex. Two others, Vioxx and Bextra, were taken off the market after they caused an ... EmpowHer (blog)

A dose of Dubai jail  -  ‎Oct 24, 2009‎
Rocky Sharma and Stephen Macleod said they went through a “nightmare� after the arthritis drug Celebrex was found in Macleod's bag. ... 7DAYS

Vt. testimony sharply divided on free drug samples  -  ‎Oct 27, 2009‎
..."Among adults two of the most sampled drugs in 2002 were Vioxx and Celebrex, obviously found within a year or two to have very serious and lethal heart ... The Associated Press

Medicare Drug Plans: Shop Around – You Can Save Thousands of Dollars a Year  -  ‎Nov 10, 2009‎
The five drugs in the package are Altace 10mg (for high blood pressure), Celebrex 200mg (for arthritis type pain), Lipitor 10mg (for high cholesterol), ... Kansas City infoZine

Let hospitals hire doctors  -  ‎Nov 2, 2009‎
Medications such as Vioxx, Celebrex, Cylert, Halcion, and Clioquinol are just a few of the examples of treatments that have caused severe illnesses - even ... San Bernardino Sun

Conflicts of interest? Dr. Mehmet Oz owns 150000 option shares in vaccine ...  -  ‎Nov 11, 2009‎
...sponsors of RealAge include most of the major drug companies and their most profitable pharmaceutical products such as Adderall, Ambien and Celebrex. ... Prison Planet.com

Local woman feels effects of Pfizer lawsuit  -  ‎Oct 30, 2009‎
Some of those drugs included Bextra, Vioxx, Celebrex, Effexor XR and Lyrica. Part of the settlement – $1 billion – will go to health care programs to ... Siskiyou Daily News

Obama Healthcare Reforms Fall Short, but Betterthanmedicare.com Closes the  -  ‎Nov 6, 2009‎
This particular patient takes one 75-mg Plavix tablet daily, one 20-mg Lipitor tablet and a 200-mg capsule of Celebrex. Regular retail costs would run her ... PR Newswire (press release)

The Expanding and Evolving Role of State Attorneys General in Drug and Device ...  -  ‎Nov 11, 2009‎
October produced two large settlements, as Pfizer agreed to pay 33 states $60 million to resolve investigations involving Celebrex and Bextra, ... Linex Legal (registration)

Advanced BioHealing Announces Key Executive Promotions  -  ‎Oct 20, 2009‎
Tozer also spent 10 years in the global pharmaceutical arena and was a commercial team lead for the global launch of Celebrex. ... Reuters

One-time gains boost AstraZeneca's 3Q  -  ‎Oct 29, 2009‎
Concerns over the safety of COX-2 inhibitors, such as Vioxx and Celebrex, could help stimulate increased sales of proton pump inhibitors such as Nexium. ... Hemscott

You...PMS-Free!  -  ‎Nov 4, 2009‎
...or to ask your doctor for a nonsteroidal anti-inflammatory drug, such as Celebrex or Vioxx, which stops the production of prostaglandins. ... MSN Health & Fitness

REG-Pfizer Inc Pfizer Reports Third-Quarter 2009 Results  -  ‎Oct 20, 2009‎
Examples of products in this business unit include, but are not limited to, Lipitor, Lyrica, Celebrex and Viagra. All revenues for such products are ... Reuters

Brigham Young University Awarded $852K in Ongoing Lawsuit with Pfizer  -  ‎Oct 30, 2009‎
BYU claims a professor's research provided to Pfizer's predecessor, Monsanto, helped create the anti-inflammatory drug Celebrex. ... Pharmaceutical Processing

ACR: Tanezumab Keeps OA Knee Pain Under Control  -  ‎Oct 23, 2009‎
For example, the COX-2 inhibitor celecoxib (Celebrex) retails for about $1500 per year at the most common dosage. Joanne Jordan, MD, MPH, director of the ... MedPage Today

Alumnus Walter Hauck III Of Old Lyme Honored By The University Of Hartford  -  ‎Oct 20, 2009‎
He was a research and development team member for several drug approval teams, including Geodon, Viagra and Celebrex. Hauck began his professional career in ... Hartford Courant

Swine Flu: Is Meditation the Best Medication?  -  ‎Oct 25, 2009‎
A report by Life Extension magazine found that such well-known drugs as Celebrex, Lipitor, and Prozac had enormous mark-ups, topped by Xanaz, marked-up from ... Center for Research on Globalization

Pfizer quiere agrandar su rebanada del pastel  -  ‎Oct 21, 2009‎
Hablando de los productos que empujarán sus metas de venta, se refirió a Lirica, su tratamiento contra el dolor neuropático y fibromialgia, Celebrex, ... El Economista.com.mx

Pfizer erhöht nach Wyeth-Übernahme erneut Prognose 2009  -  ‎Oct 20, 2009‎
Die Erlöse der Potenzpille Viagra sanken um 8% auf 466 Mio USD, die Nachfrage für das Schmerzmittel Celebrex ging um 4% auf 602 Mio USD zurück. ... FOCUS Online

Pfizer outperform  -  ‎Oct 22, 2009‎
..."Celebrex" und "Lyrica" hätten die Umsatzschätzung der Credit Suisse-Analysten um 36 Mio. bzw. 13 Mio. USD übertroffen. Nach dem soliden dritten Quartal ... FINANZEN.NET NEWS

Les résultats des laboratoires dopés par des baisses de coûts  -  ‎Oct 22, 2009‎
...car les recettes issues de produits dont les brevets sont désormais libres, tels que le Norvasc, le Celebrex, et le Viagra, ont reculé. ... Le Point

Bénéfice trimestriel en hausse et meilleur que prévu pour Pfizer  -  ‎Oct 20, 2009‎
...-4% à 602 millions de dollars pour le Celebrex (anti-douleur) et -8% à 466 millions de dollars pour le Viagra (dysfonctionnements érectiles). Le Point

Celebrex's safety data was inadequate, panel says  -  Feb 16, 2005
The committee is meeting to discuss the future of Celebrex, Bextra and other COX-2 inhibitor drugs not yet on the market. The group is expected to make ... USA Today

Saving Celebrex  -  Dec 13, 2005
On Aug. 22, the Monday after Merck was slammed with a multimillion-dollar verdict in the first trial related to Vioxx, Pfizer brought a team of academic ... Forbes

Message Mixed From Celebrex | Pharmaceuticals News | Print Financial ...  -  Apr 3, 2006
Pfizer (PFE Quote) says two studies show the arthritis drug Celebrex helps halt the growth of precancerous colon polyps that can lead to cancer. ... TheStreet.com - TheStreet.com (subscription)

FDA Panel Says Celebrex Should Stay on Market  -  Feb 18, 2005
By AP. WASHINGTON - Advisers to the Food and Drug Administration concluded Friday that the popular painkiller Celebrex poses an increased risk for heart ... New York Times

FDA Panel OKs Celebrex Use for Children  -  Nov 29, 2006
By ANDREW BRIDGES, AP Writer. WASHINGTON — Federal advisers recommended Wednesday that Pfizer Inc. be allowed to market the painkiller Celebrex as a ... FOXNews

Pfizer to settle Bextra, Celebrex lawsuits  -  Oct 17, 2008
By Ransdell Pierson. NEW YORK (Reuters) - Pfizer Inc said on Friday it plans to pay $894 million to settle lawsuits alleging that its withdrawn Bextra ... Reuters UK

FDA: Celebrex, Bextra TV Ads Misleading, Illegal  -  Jan 14, 2005
Advertisements for the arthritis drug Celebrex (search) were misleading and unsubstantiated, overstating the pain reliever's benefits and understating the ... FOXNews

Celebrex Commercial Draws Criticism  -  Apr 10, 2007
By STEPHANIE SAUL. A new television advertisement for Pfizer's painkiller Celebrex that has attracted attention for both its length and innovative marketing ... New York Times

Pfizer to Settle Claims Over Bextra and Celebrex  -  Oct 18, 2008
By STEPHANIE SAUL. Pfizer said Friday it had agreed to set aside $894 million to settle virtually all the lawsuits related to its withdrawn painkiller ... New York Times

Pfizer to resume airing ads for Celebrex  -  Apr 2, 2007
By Julie Schmit. Pfizer plans to launch a 2½-minute TV commercial today for arthritis painkiller Celebrex, which has been off TV for more than two years due ... USA Today

Pfizer leader steps up to plate for Celebrex  -  Jan 3, 2005
On Sept. 30, Merck (MRK) withdrew its blockbuster pain reliever, Vioxx — the biggest recall in the drug industry's history. By Robert Deutsch, USA TODAY ... USA Today

Celebrex: Colon Benefit, Heart Risk  -  Aug 30, 2006
By none. New studies find that Celebrex's heart risks outweigh its polyp prevention benefit for the average person. (AP). Key events involving the safety of ... CBS News

Bextra sales to stop; Celebrex adds warning.  -  Apr 8, 2005
Apr. 8--WASHINGTON -- Pfizer Inc. yesterday agreed to stop selling the painkiller Bextra and will add the government's sternest safety warning to its ... Free with registration - Boston Globe - AccessMyLibrary.com

Celebrex, Naproxen Won't Prevent Mental Decline  -  May 12, 2008
By Amanda Gardner. MONDAY, May 12 (HealthDay News) -- Contrary to prior studies, a new trial shows that daily use of two popular pain-relieving drugs, ... Washington Post

Some patients back on Celebrex  -  Aug 31, 2006
By Julie Schmit, USA TODAY. Two years after safety concerns bloodied and bruised the arthritis painkiller market, Pfizer's Celebrex is making a comeback. ... USA Today

Advocacy Group Attacks New Celebrex TV Ad  -  Apr 9, 2007
A new television commercial for the painkiller Celebrex was launched last week, two years after ads for the drug were pulled off the air at the request of ... ABC News

How Celebrex Could Recover Its Sheen  -  Feb 23, 2005
NEW YORK - Less than a month after Merck's Vioxx was yanked from the market, Pfizer announced a bold move. It was so confident in its rival arthritis ... Forbes

Pfizer gets sued over Celebrex - Feb. 27, 2006  -  Feb 27, 2006
By Aaron Smith, CNNMoney.com staff writer. NEW YORK (CNNMoney.com staff writer) - The first Celebrex lawsuit in the country, filed by a stroke survivor ... CNNMoney.com

Pfizer reaches deal with some Celebrex users: report  -  May 3, 2008
NEW YORK (Reuters) - Pfizer Inc has reached tentative deals with some patients who claim to have suffered heart attacks and strokes from taking the ... Reuters India

RPT-UPDATE 2-Pfizer says Canadian court blocks generic Celebrex  -  Apr 30, 2007
By Ransdell Pierson. NEW YORK, April 30 (Reuters) - Pfizer Inc. (PFE.N) said on Monday the Federal Court of Appeal of Canada has blocked generic drugmaker ... Reuters

Pfizer reveals study linking Celebrex to heart risks.  -  Feb 1, 2005
Feb. 1--WASHINGTON -- Pfizer Inc. has revealed it completed a study four years ago that links its painkiller Celebrex to a "statistically significant" ... Free with registration - Boston Globe - AccessMyLibrary.com

Arthritis Drug Celebrex Approved for Kids, Despite Safety Concerns  -  Nov 30, 2006
WASHINGTON — Federal advisers recommended Wednesday that Pfizer Inc. be allowed to market the painkiller Celebrex as a treatment for children with a ... FOXNews

Pfizer's Celebrex at High Doses May Raise Heart Attack Risk  -  Mar 31, 2008
By Shannon Pettypiece. March 31 (Bloomberg) -- Pfizer Inc.'s painkiller Celebrex, prescribed 11 million times last year, poses a danger to the hearts of ... Bloomberg

Second Opinion: Return of the killer painkillers? - Second Opinion-...  -  Apr 10, 2007
The FDA allowed Pfizer, maker of Celebrex, to keep that drug on the ... Vioxx and Celebrex are the best-known drugs in a class called Cox-2 inhibitors. ... msnbc.com

FDA Approves New Use for Celebrex  -  Dec 16, 2006
By Robert Steyer 12/16/06 - 06:10 PM EST. The Food and Drug Administration says Pfizer's(PFE Quote) pain reliever Celebrex can be used to treat juvenile ... TheStreet.com - TheStreet.com (subscription)

Pfizer reaches deal with some Celebrex users-WSJ  -  May 2, 2008
NEW YORK, May 2 (Reuters) - Pfizer Inc (PFE.N) has reached tentative deals with some patients who claim to have suffered heart attacks and strokes from ... Reuters

Debate Over Celebrex Safety Continues  -  Feb 3, 2005
By Todd Zwillich. Two conflicting studies on the pain relief drug Celebrex (search ) are deepening questions over whether the drug's benefits are worth the ... FOXNews

Pfizer's Celebrex patents upheld vs. Teva challenge  -  Mar 20, 2007
NEW YORK, March 20 (Reuters) - Pfizer Inc. (PFE.N) said on Tuesday a US court upheld the three main patents covering its Celebrex arthritis treatment, ... Reuters

For Former Vioxx Users, Celebrex May Be an Option  -  Sep 12, 2006
By RYAN STANTON, MD, ABC News Medical Unit. The painkiller Celebrex may be safe for some patients who suffer from chronic bone and joint pain, ... ABC News

Celebrex shows promise in lung cancer prevention  -  Jun 1, 2008
By Julie Steenhuysen. CHICAGO (Reuters) - A high dose of the arthritis drug Celebrex showed early signs that it may help prevent lung cancer in heavy ... Reuters India

Pfizer wins ruling that may limit Celebrex lawsuits  -  Nov 20, 2007
NEW YORK (Reuters) - Pfizer Inc has won a US court ruling that could limit lawsuits alleging its painkiller Celebrex caused heart attacks and strokes. ... Reuters

Vioxx, Celebrex overpromoted, study says Older, cheaper drugs seen as...  -  Jan 25, 2005
A majority of the patients who were persuaded to use prescription arthritis drugs such as Celebrex and Vioxx would have done just as well on older, ... San Francisco Chronicle

Celebrex-Lipitor combination may halt prostate cancer, US researchers...  -  Apr 15, 2008
WASHINGTON, April 14 (Xinhua) -- Administering a combination of the widely used drugs Celebrex, an anti-inflammatory drug, and Lipitor, ... 新�网

Pfizer's Celebrex Risk Gets Worse  -  Jan 19, 2005
NEW YORK - Pfizer's earnings are still growing fast, but the risk due to pain drugs Celebrex and Bextra is only increasing. ... Forbes

Tea Antioxidant Plus Celebrex May Fight Prostate Cancer  -  Mar 2, 2007
FRIDAY, March 2 (HealthDay News) -- A component of green tea, combined with low doses of the cox-2 inhibitor painkiller Celebrex, may be able to slow ... Washington Post

Judge calls Celebrex evidence unreliable  -  Jan 10, 2008
NEW YORK (AP) — A state court has ruled that plaintiffs suing Pfizer Inc. over its pain medication Celebrex do not have reliable scientific evidence to ... USA Today

As trial looms, Celebrex eases Pfizer sales pain  -  Mar 2, 2006
Even as the painkiller Celebrex heads for its first product- liability trial, the drug is making a comeback of sorts for its maker, Pfizer Inc. ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Watchdog Asks FDA to Stop Celebrex Ad  -  Apr 9, 2007
A consumer advocacy group called on the government Monday to order Pfizer Inc. to stop running a television ad for painkiller Celebrex, calling the ad ... FOXNews

Some Patients Sticking By Celebrex  -  Jan 24, 2005
By Jaime Holguin. While the FDA comes under fire over the sale of Celebrex and Bextra, new studies suggest that taking the drugs is neither easier on the ... CBS News

Celebrex may prevent colon cancer but still risky for heart, studies...  -  Apr 4, 2006
By MARILYNN MARCHIONE. AP. WASHINGTON — Is a drug that might lower the risk of colon cancer worth taking if it also raises the risk of heart problems? ... Seattle Times

Ahead of the Bell: Celebrex Review  -  Mar 25, 2008
WASHINGTON (AP) - A group of government experts on Tuesday will review the safety of a handful of drugs when used in children. ... Forbes

Pfizer says 17 European countries extend Celebrex arthritis drug label  -  Feb 23, 2007
LONDON (AFX) - Pfizer Inc said 17 European countries have agreed to extend the Celebrex drug label to include symptomatic relief in the treatment of ... Forbes

Pfizer Says 1999 Trials Revealed Risks With Celebrex  -  Feb 1, 2005
By ALEX BERENSON AND GARDINER HARRIS. Celebrex, the popular arthritis and pain medicine from Pfizer, sustained another blow yesterday when the company ... New York Times

Celebrex disrupts heart rhythm in fruit flies  -  Jan 26, 2008
By Julie Steenhuysen. CHICAGO (Reuters) - Celebrex, an arthritis drug in the same class as the recalled painkiller Vioxx, caused irregular heartbeats in ... Reuters India

Heart Experts Issue Guidelines on Use of Celebrex  -  Feb 26, 2007
MONDAY, Feb. 26 (HealthDay News) -- The American Heart Association is weighing in on the potential heart dangers of controversial cox-2 nonsteroidal ... Washington Post

Readers' Questions Answered - Celebrex and Colon Cancer - Denise …  -  Sep 8, 2006
By DENISE GRADY. Q. In your research did you find any information regarding the use of Celebrex (or other NSAIDs) and breast cancer prevention or control? ... New York Times

Celebrex-Lipitor combo may fight prostate cancer  -  Apr 14, 2008
By Deena Beasley. SAN DIEGO (Reuters) - The combination of anti-inflammatory and cholesterol-lowering drugs may be able to stop the progression of prostate ... Reuters

Celebrex not as risky as Vioxx, study suggests  -  Feb 2, 2005
Low-dose anti-inflammatory drugs such as Celebrex don't seem to be as dangerous as Vioxx for seniors with no history of heart attacks, a Montreal study ... CBC.ca

Pfizer, FDA talks could bring ads for Celebrex back to television  -  Mar 29, 2007
The controversial arthritis pain pill Celebrex could return to television in new ads by this summer pending negotiations under way between the drug's maker, ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Old, 'safe' painkillers found to cause same heart ills as new  -  Sep 13, 2006
Celecoxib (brand name Celebrex) -- which is still available -- may cause heart problems, ... He said that while the data on Celebrex look relatively good, ... Globe and Mail

Court ruling protects Pfizer's Celebrex  -  Mar 7, 2008
NEW YORK (AP) - Pfizer Inc. said Friday an appeals court has upheld patents on its pain drug Celebrex, preventing a generic drug competitor from launching a ... Forbes

FDA approves Celebrex for spinal arthritis  -  Aug 1, 2005
AP. NEW YORK (AP) — Pfizer Inc. said Monday the Food and Drug Administration approved and finalized prescription information of painkiller Celebrex for the ... MLive.com

Celebrex Ads Are Back, Dire Warnings and All  -  Apr 29, 2006
By ALEX BERENSON. The ads for the Pfizer painkiller Celebrex feature a man holding a boy's hand as they walk up a stadium staircase. ... New York Times

How safe is Celebrex?  -  Feb 25, 2007
The FDA has thousands of accounts suggesting the painkiller may be linked to heart attacks. Critics are unsure if flaw is in drug or agency's reporting ... Boston Globe

Pfizer says ruling favorable in NY Celebrex case  -  Jan 9, 2008
LOS ANGELES (Reuters) - US drugmaker Pfizer Inc (PFE.N) said on Wednesday a New York State court ruling related to litigation over the company's painkiller ... Reuters

Pfizer CEO sees Celebrex rebound  -  Nov 7, 2005
NEW YORK (Reuters) - Pfizer Inc. (PFE.N) Chief Executive Officer Hank McKinnell on Monday said he expects sales of the company's Celebrex arthritis drug to ... Reuters

Pfizer hit over new ads for Celebrex  -  Apr 19, 2006
By Bloomberg News | April 19, 2006. WASHINGTON -- Pfizer Inc. is advertising its Celebrex arthritis medicine again, a year after US regulators asked the ... Boston Globe

MoH Still to Act as FDA Approves Cox-2 Class Drugs  -  Mar 4, 2005
18, members of the FDA advisory panel voted to recommend keeping Bextra and Celebrex on the market. The Celebrex vote was an overwhelming 30-1. ... Arab News

Drug firms taking hard look at ads after Vioxx, Celebrex  -  Feb 25, 2005
Ads starring Olympic gold-medal skater Dorothy Hamill helped send sales of the pain reliever Vioxx soaring. And a catchy tune reminding arthritis sufferers ... $2.95 - Kansas City Star - NewsBank

For those in pain, relief trumps risks of banned painkillers  -  Jan 4, 2005
Vioxx, Celebrex and Bextra belong to a class of painkillers known as COX-2 inhibitors ... But a study in 2001 that set out to prove that Celebrex provided a ... USA Today

Pfizer Recovers Some Loss in Shift to Celebrex; Its arthritis...  -  May 18, 2005
Celebrex, like Bextra and the also-withdrawn Vioxx from Merck & Co., belongs to a class of drugs known as Cox-2 inhibitors. Last year all were linked to an ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

HARD SELL: HOW MARKETING DRIVES THE PHARMACEUTICAL …  -  Feb 27, 2005
The painkillers Vioxx, Celebrex and Bextra may go down in history as a classic example of the ... When Vioxx and Celebrex hit the market in the late 1990s, ... San Francisco Chronicle

Suffering Boomers want to fill Vioxx void: Celebrex sales surge...  -  Mar 23, 2007
Mar. 23--Given the option of living with pain or an increased heart attack risk, some Baby Boomers are assuming the risk and going back to a drug still ... Free with registration - Chicago Tribune - AccessMyLibrary.com

Pfizer Says Internal Studies Showed No Celebrex Risks  -  Feb 5, 2005
Pfizer has told federal regulators that the company's analysis of 41 of its patient trials of the arthritis and pain drug Celebrex found no evidence that ... New York Times

Pfizer reveals $4bn cost-cutting plan  -  Apr 6, 2005
It said a 50 per cent drop in prescriptions for Celebrex and another Cox-2 inhibitor drug, Bextra, were contributory factors in its need to reduce forecasts ... Independent

Article: FDA Actions Leave Pfizer's Celebrex Without Rival - The …  -  Apr 8, 2005
FDA Actions Leave Pfizer's Celebrex Without Rival ... find The Washington Post articles. While federal regulators forced Pfizer Inc. to pull a billion- ... Pay-Per-View - Washington Post - HighBeam Research

Celebrex sales will be flat in 2006: analysts - Jun. 29, 2005  -  Jun 29, 2005
By Aaron Smith, CNN/Money staff writer. NEW YORK (CNN/Money) - The health risks surrounding arthritis painkillers have caused physicians to back away from ... CNNMoney.com

Arthritis painkillers fallen from grace, FDA gathering info - Feb....  -  Feb 10, 2006
Pfizer's Celebrex remains on the market to this day, but sales have been cut ... Rubin of Morgan Stanley said that not only will Celebrex always have that ... CNN

Pfizer Gets European Request for More Celebrex Data  -  Jan 20, 2005
By Angela Zimm. Jan. 20 (Bloomberg) -- European health regulators asked Pfizer Inc., the world's biggest drugmaker, for more information from a study that ... Bloomberg

Timeline: Pain Reliever Controversy  -  Aug 19, 2005
17, 2004: A cancer-prevention study shows that Celebrex more than doubled ... 24, 2005: A study in the Archives of Internal Medicine says Celebrex and Vioxx ... FOXNews

New study links pain killers to cardio problems  -  Feb 14, 2005
NEW YORK -- A new study has linked pain killers Vioxx, Celebrex and Bextra to ... Vioxx and Celebrex increased patients' risk of heart attack and stroke by ... CTV.ca

Vioxx's Heart Risk Lingered Long After Use Ended  -  Oct 14, 2008
There is a dose-dependent risk with Celebrex as well, whose magnitude was not that ... Whether or not other drugs like Celebrex shared that isn't known. ... Washington Post

Editorial Urges "Black-Box" Warning for Bextra and Celebrex  -  Jan 18, 2005
Newswise — Physicians should avoid prescribing Bextra altogether, or use it only as a drug of last resort, says a researcher from Wake Forest University ... newswise.com

Atlanta health, diet and fitness news | ajc.com  -  Jan 29, 2005
Bextra, along with Vioxx and Celebrex, belong to a class of drugs known as cox-2 inhibitors. ... Celebrex, another Pfizer drug, remains on pharmacy shelves. ... Atlanta Journal Constitution

Arthritis pill gains in respect and price.  -  Feb 6, 2005
At the time, painkillers Vioxx and Celebrex were in the spotlight, billed as new ... The commonly prescribed dose of Celebrex, a 200 mg pill, costs $3.26. ... Free with registration - Chicago Tribune - AccessMyLibrary.com

Celebrex may fight cancer, but with risks- msnbc.com  -  Apr 24, 2006
WASHINGTON - A popular arthritis drug that seems to raise the risk of heart problems also seems to lower the risk of growths that lead to colon cancer, ... msnbc.com

Panel says Celebrex for kids should get OK  -  Nov 30, 2006
By Andrew Bridges. AP. WASHINGTON — Federal advisers recommended Wednesday that Pfizer be allowed to market the painkiller Celebrex as a treatment for ... Seattle Times

The FDA's medicine is just what Pfizer needs  -  Apr 10, 2005
For one thing, it followed on the heels of concerns raised last autumn about the safety of Celebrex, Pfizer's blockbuster painkiller, and the withdrawal ... Telegraph.co.uk

Study: Vioxx ups pressure; Celebrex doesn't.  -  Jan 27, 2005
Jan. 27--The blood pressure of arthritis patients rose significantly after they began taking the pain reliever Vioxx, but no such increase was noted in the ... Free with registration - Hartford Courant - AccessMyLibrary.com

Pfizer profit slides 52%; 2005 outlook cut - MarketWatch  -  Oct 20, 2005
Sales of the company's pain reliever Celebrex came in at $446 million, a slide of 44%. ... Celebrex sales have been under pressure since rival Merck & Co. ... MarketWatch

Pfizer could make $2 billion sales goal for Celebrex - Sep. 21, 2006  -  Sep 21, 2006
With Merck's Vioxx gone, Pfizer's Celebrex enjoys monopoly status, but can the Cox-2 arthritis drug market come back? By Aaron Smith, CNNMoney.com staff ... CNNMoney.com

Pfizer knocked by drug suspension  -  Apr 19, 2005
The FDA said Celebrex also increased the possible risk of heart attack or stroke. Pfizer now expects its overall 2005 earnings to fall by almost 7% to $1.98 ... BBC News

Study: Celebrex as risky as Vioxx  -  Apr 15, 2005
A study of New Zealand patients on two previously common arthritis drugs has found a similar risk of heart attacks and strokes regardless of the brand. ... TVNZ

Ibuprofen link to heart attack risk  -  Jun 10, 2005
..."For many patients, Celebrex can provide pain relief that is not achieved with alternative therapies such as NSAIDs which cannot be easily used for long ... Telegraph.co.uk

Pfizer Profit Probably Rose on Revived Celebrex Sales  -  Oct 18, 2006
By Shannon Pettypiece. Oct. 18 (Bloomberg) -- Pfizer Inc. is likely to report higher third-quarter profit after the world's largest drugmaker revived sales ... Bloomberg

Pfizer will fund study on safety of Celebrex | Article from Internatio...  -  Dec 15, 2005
Pfizer will fund study on safety of Celebrex ... find International Herald Tribune articles. Stephanie Saul International Herald Tribune 12-15-2005 Pfizer, ... Pay-Per-View - International Herald Tribune - HighBeam Research

Celebrex's new role in killing cancer?  -  May 17, 2007
They found the Cox-2 inhibitor pain drug celecoxib (Celebrex) worked the best, ... The team tested the effects of celecoxib (Celebrex), sulindac sulfide ... United Press International

Taking Pains With Painkillers .After Ok, .Tion, .You Outfit To Hut...  -  Feb 20, 2005
Unfortunately, many pa tients who are candidates for Celebrex, Vioxx and Bextra, ... Many patients can avoid taking Celebrex, Bextra or Vioxx altogether by ... Milwaukee Journal Sentinel - Google News Archive

SEC asking Pfizer for data on Bextra, Celebrex  -  Aug 9, 2005
By MADLEN READ. AP. NEW YORK (AP) — Pfizer Inc. is responding to a request from the Securities and Exchange Commission for information and documents on its ... MLive.com

Celebrex No Help Against Alzheimer's Disease  -  May 13, 2008
A large government experiment has offered disappointing results. It was hoped a link could be found between Celebrex and Aleve and improved function in ... Newsinferno.com

Canada Panel Backs Vioxx Return  -  Jul 7, 2005
The Canadian advisory panel also voted unanimously that Celebrex, ... The panel voted 31-1 that Celebrex remain available in the US market. ... TheStreet.com - TheStreet.com (subscription)

Celebrex warning hurts Pfizer  -  Oct 21, 2005
Pfizer Inc. The world's biggest drugmaker said third-quarter earnings plunged 52 percent on lower sales of its Celebrex painkiller and Neurontin epilepsy ... Pay-Per-View - Newsday - ProQuest Archiver

Commentary: Side Effects Of The Drug Scares  -  Mar 7, 2005
Another study fingered Celebrex, a similar drug made by rival Pfizer Inc. (PFE ). ... Putting limits or warnings on Celebrex thus "risks bringing about an ... BusinessWeek

FDA Approves Celebrex for Spinal Arthritis  -  Aug 2, 2005
Pfizer Inc. said Monday the Food and Drug Administration approved and finalized prescription information of painkiller Celebrex (search) for the treatment ... FOXNews

Canadian warning adds to Merck's troubles over Vioxx  -  May 3, 2006
..."Our previous study on COX-2 inhibitors, which included Vioxx and Celebrex, evaluated whether there was an increased risk of heart attack while taking these ... Independent

Celebrex Trial Is Delayed  -  Jun 6, 2006
The first trial over claims that Pfizer Inc.'s painkiller Celebrex causes strokes, set to start today in an Alabama state court, was postponed to give ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Supplements do little for arthritis, study finds  -  Feb 23, 2006
The drug Celebrex did reduce pain – 70 per cent reported improvement – affirming the study's validity, but it is being studied to see if it is safe for ... Globe and Mail

Pfizer looking to put Bextra back on market.  -  May 12, 2005
In a 19-page memo issued April 6, the FDA explained why it is adding its sternest warning to the label for Pfizer's Celebrex and why it recommended halting ... Free with registration - Boston Globe - AccessMyLibrary.com

Article: Celebrex still on the mart - New Straits Times | HighBeam …  -  Jan 19, 2005
Celebrex still on the mart ... find New Straits Times articles. Dr Wong Kok Seng New Straits Times 01-19-2005 Celebrex still on the mart Byline: Dr Wong Kok ... Pay-Per-View - New Straits Times - HighBeam Research

Polyp stopper: controversial drug may prevent colon growths.(Celebrex)  -  Apr 8, 2006
An anti-inflammatory drug currently prescribed for arthritis and pain can prevent formation of precancerous growths in the colon and rectum, two analyses ... Free with registration - Science News - AccessMyLibrary.com

Brand Names/Synonyms:
Celebrex is also known by the following brand names and/or synonymsCelebra; Celebrex; Celecoxib; Celocoxib; HSDB 7038; YM 177

Drug Category:
Celebrex is categorized under the following by the FDA: Cyclooxygenase Inhibitors; Anti-inflammatory Agents; Nonsteroidal Antiinflammatory Agents (NSAIDs); ATC:L01XX33; ATC:M01AH01

Dosage Forms:
CELEBREX oral capsules contain 100 mg and 200 mg of celecoxib.

Absorption:
When CELEBREX capsules were taken with a high fat meal, peak plasma levels were delayed for about 1 to 2 hours with an increase in total absorption (AUC) of 10% to 20%. Coadministration of CELEBREX with an aluminum-and magnesium-containing antacid resulted in a reduction in plasma celecoxib concentrations with a decrease of 37% in Cmax and 10% in A.C. CELEBREX capsules can be administered without regard to the timing of meals.

Interactions:
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Chemical IUPAC Name:
4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide





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