Chlorpheniramine

This page contains recent news articles, when available, and an overview of Chlorpheniramine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Chlorpheniramine
(when available)

Pharmacology and use:
In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Chlorpheniramine, is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies. For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.

Mechanism Of Action:
Chlorpheniramine binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.

News Articles on Chlorpheniramine

Suspect's apartment yields possible clues, questions  -  ‎Nov 11, 2009‎
Chlorpheniramine is also an allergy drug. Its side effects are generally benign, the agency reports. Benzonatate, a cough suppressant, is used to treat ... Austin American-Statesman

Apartment offers a peek at the Fort Hood suspect  -  ‎Nov 12, 2009‎
Also in the box were bottles of benzonatate, a prescription cough medicine, and chlorpheniramine, an antihistamine, from Walter Reed Army Medical Center; ... San Antonio Express

Nothing to Sneeze At  -  ‎Nov 3, 2009‎
Dr. Pray recommends Chlorpheniramine. According to Dr. Pray, Loratadine "carries a warning against use in liver or kidney disease. Chlorpheniramine is safe ... ABC2 News

Curing a cold when your mom isn't around  -  ‎Nov 9, 2009‎
The older antihistamines, such as brompheniramine and chlorpheniramine, are the only antihistamines effective at relieving cold symptoms. ... Chicago Flame Online (subscription)

Promising early results for UCB's new products  -  ‎Oct 22, 2009‎
Net sales of Tussionex (hydrocodone polistirex and chlorpheniramine polistirex) declined due to the mild cough and cold season in the US earlier in the year ... The FINANCIAL

Rapport intermédiaire - Premiers résultats prometteurs pour les nouveaux ...  -  ‎Oct 21, 2009‎
Les ventes nettes de Tussionex® (hydrocodone polistirex et chlorpheniramine polistirex) ont régressé en raison d'une saison hivernale relativement douce aux ... Euronext (persbericht)

Tussentijds rapport - Veelbelovende eerste resultaten voor nieuwe producten ...  -  ‎Oct 21, 2009‎
De nettoverkoop van Tussionex® (hydrocodone polistirex en chlorpheniramine polistirex) is gedaald omwille van het zachte hoest- en verkoudhedenseizoen in de ... Analist.be (persbericht)

3 tips on allergy medicines  -  ‎Aug 25, 2009‎
But older drugs (such as chlorpheniramine and diphenhydramine) can be dangerously sedating. And "among the newer, non-sedating antihistamines, USA Today

A survival guide to the flu  -  ‎Aug 25, 2009‎
Cough and cold medications containing chlorpheniramine, diphenhydramine, pseudoephedrine and lozenges with dyclonine, glycerin or honey can help ease San Diego Union Tribune

SWINE FLU SURVIVAL KIT  -  ‎Aug 5, 2009‎
Fever reducers, such as acetaminophen, ibuprofen, Cough and cold medications containing chlorpheniramine, diphenhydramine, oxymetazoline, Weekly World News (satire)

Get Tips on Preventing, Treating Swine Flu  -  ‎Aug 4, 2009‎
Cough and cold medications must contain: chlorpheniramine, diphenhydramine, oxymetazoline and pseudoephedrine. Chlorpheniramine and diphenhydramine are both ABC News

Consumer Reports: Prescriptions for what ails you  -  ‎Aug 21, 2009‎
If necessary, CR suggests trying to dry up the postnasal drip that causes cold-related coughs with an older antihistamine, such as chlorpheniramine Newton Daily News

Consumer Reports Swine Flu Survival Kit Prepares Consumers for ...  -  ‎Aug 3, 2009‎
Cough and cold medications containing chlorpheniramine, diphenhydramine, oxymetazoline, and pseudoephedrine and lozenges with dyclonine, glycerin, PR Newswire (press release)

抗击æµ?感,童童有责?  -  ‎Aug 20, 2009‎
...于是,我家两个å°?家伙,从å?„自ç?­ä¸Šéš?ç?€å¤§é˜Ÿï¼ˆfollow the crowd)到礼堂,é‡?é‡?体温,ä¸?约而å?Œå¸¦å›žä¸€å¼ â€œéš”离纸â€?和黄橙二色两包丸仔(chlorpheniramine maleateå’Œascorbic 独立新闻在线

Cough, Cold Mixtures Unsuitable For Children Below Two  -  ‎Jul 8, 2009‎
Products affected are oral liquid preparations containing antihistamines (such as Brompheniramine, Chlorpheniramine, Clemastine, Dexbropheniramine, Bernama

Grand Jury: No Case Vs. Dr. In Girl's Death  -  ‎Jul 1, 2009‎
The medical examiner's autopsy indicated that she died from a toxic combination of clonidine, Depakote, dextromethorphan, and chlorpheniramine. Boston Channel.com

Alert on 2 illegal health items  -  ‎Jun 17, 2009‎
...chlorpheniramine and pheniramine are antihistamines used to treat allergy symptoms. Adverse effects of these substances include drowsiness, Straits Times

HONG KONG: Health authority orders tea removal - report  -  ‎Jun 18, 2009‎
Samples taken from herbal tea shops in Tai Kok Tsui, Kowloon City and Tai Wo Hau contained either paracetamol or both paracetamol and chlorpheniramine and just-drinks.com (subscription)

Hong Kong Bans Chinese Herbal Teas Containing Paracetamol and ...  -  ‎Jun 17, 2009‎
Samples taken from herbal tea shops in Tai Kok Tsui, Kowloon City and Tai Wo Hau contained either paracetamol or both paracetamol and chlorpheniramine. FLEXNEWS

Dawa Ltd yet again in drug scam  -  ‎Jun 23, 2009‎
CCI show the consignment comprised of 6300 vials of Benzathine Penicillin (2.4mega), another 3360001 mega vials and 33600 Chlorpheniramine injections. Standard

涼茶å?«è¥¿è—¥ 勒令å?œå”®  -  ‎Jun 17, 2009‎
...衛生署16æ—¥å?ˆè?¯å?Œé£Ÿç‰©ç’°å¢ƒè¡›ç”Ÿç½²ï¼Œåˆ†åˆ¥å¾žå¤§è§’å’€ã€?ä¹?é¾?城å?Šå¤§çª©å?£ä¸‰é–“涼茶舖抽å?–涼茶樣本,çµ?果發ç?¾å?«æœ‰æ’²ç†±æ?¯ç—›ï¼ˆparacetamol)å?Šæ°¯è‹¯é‚£æ•?(chlorpheniramine)兩種 世界日報

新加å?¡â€§æ‘»é›œæœªç”³å ±å¼·å‹?西藥‧ç?…城促å?œæœ?2ä¿?å?¥å“?  -  ‎Jun 18, 2009‎
...當局檢驗顯示,“Delima Raja Uratâ€?å?«4種未經申報的高效西藥æˆ?份“地塞米æ?¾â€?(dexamethasone)ã€?“撲爾æ•?â€?(chlorpheniramine)ã€?“é?žå°¼æ‹‰æ•?â€?(Pheniramine)和“西布曲 星洲日報

Common drugs can help allergic rhinitis  -  ‎Mar 29, 2009‎
Most of these products, while bearing different brand names, contain similar active ingredients such as Brompheniramine maleate (Dimetapp), Chlorpheniramine Daytona Beach News-Journal

Saving Lives through Quality Product  -  ‎Apr 13, 2009‎
...and solution contain three internationally proven active ingredients which are paracetamol, phenylephrine hydrochloride and chlorpheniramine maleate. THISDAY

Watch out for these unapproved cough and cold meds  -  ‎Apr 14, 2009‎
New Allergy DM suspension, D-Tann CT tablets, B-Vex D suspension, Histex SR, and Chlorpheniramine Maleate 12 mg/Pseudoephedrine HCl 120 mg LA tablets. Modern Medicine

FDA Obtains Permanent Injunction Barring Two Companies from ...  -  ‎Apr 13, 2009‎
The unapproved drugs manufactured by Unigen and/or Advent include, but are not limited to: Chlorpheniramine Maleate 12 mg/Pseudoephedrine HCl 120 mg LA Pharmaceutical Processing

FDA stops two firms from manufacturing, selling 50 unapproved drug ...  -  ‎Apr 10, 2009‎
New Allergy DM Suspension, D-Tann CT Tablets, B-Vex D Suspension, Histex SR, and Chlorpheniramine Maleate 12 mg/Pseudoephedrine HCl 120 mg LA Tablets. RTT News

美FDA下令å?œå”®50ç§?咳嗽和感冒è?¯  -  ‎Apr 12, 2009‎
Tann 20 mg/CP Tann 4 mgã€?BP New Allergy DMã€?B-Vex D,和è?¯ç‰‡D-Tann CTã€?Chlorpheniramine Maleate 12 mg/Pseudoephedrine HCl 120 mg LA以å?ŠHistex SR胶囊。 大纪元

50種咳嗽和感冒藥被美FDA明令ç¦?å”®  -  ‎Apr 13, 2009‎
Tann 20 mg/CP Tann 4 mgã€?BP New Allergy DMã€?B-Vex D,和藥片D-Tann CTã€?Chlorpheniramine Maleate 12 mg/Pseudoephedrine HCl 120 mg LA以å?ŠHistex SR膠囊。 希望之聲電台

09年执业西è?¯å¸ˆè?¯ç‰©åŒ–  -  ‎Apr 16, 2009‎
...例如氯苯那æ•?(Chlorpheniramine)等。此类è?¯ç‰©çš„脂溶性大于乙二胺类和氨基醚类,因此抗组胺作用强,作用时间长。 化学å??:N,N-二甲基-γ-(4-氯苯基)-2-å?¡å•¶ä¸™èƒºé¡ºä¸? 青年人

Không nên quá lo lắng bệnh vẩy nến  -  ‎Apr 2, 2009‎
Có thể dùng thêm thuốc chống ngứa, chống dị ứng như Phenecgan hoặc Chlorpheniramine lúc Ä‘i ngá»§. Không nên tiêm K-Cort hoặc uống Prednisolon vì dùng những An ninh thủ đô

Drixoral: Why the Allergy Medicine Isn't Available, and What to ...  -  ‎Mar 9, 2009‎
As an alternative to Drixoral, people can seek out medicines that combine one of two older antihistamines, chlorpheniramine or diphenhydramine, U.S. News & World Report

UCB warding off effects of patent expiries  -  ‎Mar 4, 2009‎
Sales reached 1.27 billion euros, an increase of 23%, while the anti-tussive Tussionex (hydrocodone and chlorpheniramine) grew 29% to 147 million euros, Pharma Times

UCB (BE) - UCB: Full Year 2008 Financial Results  -  ‎Mar 3, 2009‎
Net sales of the antitussive, Tussionex® (hydrocodone polistirex and chlorpheniramine polistirex), grew by 29% (+38% CER) to EUR 147 million benefiting from PharmaLive.com (press release)

Küçüklere ilaç verirken bir daha düşünün  -  ‎Mar 10, 2009‎
Aynı tarihler arasında soÄŸuk algınlığı ilaçlarında bulunan anti-histaminik özellikli diphenhydramine, brompheniramine ya da chlorpheniramine maddelerine İhlas.Net

Au secours ! Mon chat s'arrache les poils !  -  ‎Feb 27, 2009‎
Certains chats souffrant de pelade psychogène peuvent répondre à la chlorpheniramine (un antihistaminique) ou à des glucocorticoïdes systémiques. Waliboo

L'épilepsie canine  -  ‎Feb 27, 2009‎
Réaction allergique à un médicament : Chlorpheniramine (antihistaminique, surdosage), ibuprofène, aspirine ou mitotane, un médicament utilisé dans le Waliboo

Research and Markets: Top Three Drugs by Sales in Kazakhstan were ...  -  Jan 27, 2009
Novartis' over-the-counter (OTC) flu treatment Theraflu (acetaminophen + chlorpheniramine + dextromethorphan + phenylephrine + pheniramine + MarketWatch (press release)

Failure to launch  -  Jan 20, 2009
About a third of men improve after treatment with medicines that close the bladder neck, such as pseudoephedrine, phenylephrine, chlorpheniramine, Malaysia Star,

Treating colds: What works, what doesn't  -  Jan 12, 2009
Take a sustained-release first generation antihistamine (the kind that can make you drowsy) like diphenhydramine (Benadryl), chlorpheniramine (Chlotrimeton Philippine Star,

Can’t cure cold but sure can fight one  -  Jan 16, 2009
My favorite is chlorpheniramine (Chlor-Trimeton), but diphenhydramine (Benadryl) and doxylamine (Unisom) work well. Ibuprofen (Advil) or acetaminophen Greenwood Commonwealth,

GSK introduces Panadol Cold & Catarrh  -  Dec 22, 2008
Paracetamol is for fever and pain relief, phenylephrine hydrochloride to decongest the nose and chlorpheniramine maleate to strongly prevent allergic body Vanguard,

WHEN TAKING CARE OF YOUR COUGH  -  Dec 18, 2008
TussiCaps® is the first and only FDA-approved hydrocodone/chlorpheniramine capsule for the relief of cold-related cough in adults and children 6 years of North American Press Syndicate,

Health warning issued under Section 98 of the Medicines Act 1981  -  Dec 9, 2008
Ankahuangmin Jiaonang (Paracetamol, Caffeine, Artificial Cow Bezoar and Chlorpheniramine Maleate Capsules). This product is presented as blister packs New Zealand Doctor Online,

UPI NewsTrack Health and Science News  -  Dec 18, 2008
The products affected are those containing any active ingredients that are given orally: --Antihistamines: brompheniramine maleate, chlorpheniramine maleate United Press International

Canada mandates relabeling of kids' drugs  -  Dec 18, 2008
The products affected are those containing any active ingredients that are given orally: --Antihistamines: brompheniramine maleate, chlorpheniramine maleate United Press International

China Sky One Medical, Inc. Obtains Production Rights for Two ...  -  Dec 16, 2008
Compound Naphazoline spray is for the treatment of rhinopathy; -- Naphazoline Hydrochloride Chlorpheniramine Maleate and Benzalkonium Bromide spray for SYS-CON Media,

The Promethazine and Codiene Syrup Appreciation...  -  Dec 2, 2008
...(Yellow Syrup: XR Hydrocodone and Atropine or Chlorpheniramine, Pink Syrup: Cheratussin AC brand Codeine and Guaifenesin). Cheratussin AC(and other brands), AllHipHop

Health Canada Releases Decision on the Labelling of Cough and Cold ...  -  Dec 18, 2008
...and brompheniramine maleatecold medicines chlorpheniramine maleate(used to treat sneezing, clemastine hydrogen fumeraterunny nose) dexbrompheniramine International Business Times,

懷孕å?Šå“ºä¹³æœŸçš„æ„Ÿå†’治療  -  Dec 8, 2008
HCL�Acetylcysteine;�鼻水�鼻塞�用傳統藥物如Chlorpheniramine uho優活�康網,

תרופות לל×? מרש×? למחלות חורף  -  Dec 10, 2008
...קלורפנרמין (CHLORPHENIRAMINE)- טיפול בתסמיני הצטננות, התעטשות, דמעת ונזלת. תופעת הלוו×?×™ השכיחה ביותר עקב השפעה על המח ×”×™×? רצון לישון ועייפות. BeOK פורטל ברי×?ות ויופי,

Warning over medicines sold by Chinese supermarket  -  Dec 7, 2008
The Ministry of Health is warning people not to take six medicines that have been on sale at a supermarket selling mainly Chinese goods in South Auckland. Radio New Zealand,

UCB on track  -  Oct 30, 2008
Key products contributing to growth were Keppra(R) (levetiracetam), Xyzal(R) (levocetirizine) and Tussionex(R) (hydrocodone polistirex and chlorpheniramine MarketWatch

Pharmacist weighs in on cold remedies  -  Nov 3, 2008
Antihistamines: Antihistamines are designed to treat allergies; however, some older antihistamines, such as brompheniramine, chlorpheniramine and News-Leader.com,

Safety of Kids Cough and Cold Medicines Questioned  -  Oct 27, 2008
Other deaths occurred because of the association with antihistamine medicines containing diphenhydramine, brompheniramine or chlorpheniramine. Natural News.com,

Küçüklere İlaç İçirmeyin  -  21 Oct 2008
Aynı tarihler arasında soğuk algınlığı ilaçlarında bulunan anti-histaminik özellikli diphenhydramine, brompheniramine ya da chlorpheniramine maddelerine Yeni Bursa,

FDA Hears Testimony On Children's Cold Medicine  -  Oct 2, 2008
A review of records between 1969 and 2006 shows 69 deaths associated with antihistamines, diphenhydramine, brompheniramine, and chlorpheniramine -- active KDKA,

CONSUMER REPORTS: Back to Basics For Safer Childbirth  -  Oct 8, 2008
3rd None trimester: Do not take -- unacceptable risk Chlorpheniramine Chlor- 1st, 2nd trimester: Claritin Trimeton; Use with caution (Loratadine); MarketWatch

First Aid for Bug Bites - Mosquitos, Ticks, Spiders, Bedbugs ...  -  Oct 4, 2008
For stronger bug bite reactions, Dr. Fox recommends taking an antihistamine containing diphenhydramine (Benadryl, Tylenol Severe Allergy), chlorpheniramine PR Web (press release),

Má»™t trẻ dị ứng thuốc nặng do ngưá»?i nhà tá»± Ä‘iá»?u trị  -  Oct 1, 2008
...bá»›t tổn thương Trước khi nhập viện khoảng 1 tuần, M. bị sốt, ho và sổ mÅ©i, ngưá»?i nhà tá»± mua thuốc cho bé uống gồm bactrim, toplexil, chlorpheniramine. Ngưá»?i Lao Ä?á»™ng,

China Sky One Medical develops nasal spray for rheumatic disease  -  Aug 18, 2008
...recently completed R&D for the spray, which includes the active ingredients naphazoline hydrochloride chlorpheniramine maleate and benzalkonium bromide. Trading Markets (press release),

Older People in Danger from Common Drugs  -  Aug 28, 2008
Chlorpheniramine (Chlor-Trimeton) and diphenhydramine (Benedryl) can cause drowsiness, confusion, and urine retention. Consider cetirizine (Zyrtec) NewsMax.com,

中 류마티스 비강 스프레ì?´ì œ 개발  -  Aug 22, 2008
...� 스프레�제� 활성성분� '염산나파졸린'(naphazoline hydrochloride), '�레�산�로르페니�민'(chlorpheniramine maleate), '벤잘코늄브로마�드'(benzalkonium 디지틀보사,

壯陽膠囊誇療效地下電å?°ä¸»æŒ?人é€?辦  -  Aug 26, 2008
...由於膠囊�分被驗出�有Vardenafil�Acetaminophen�Chlorpheniramine 自由時報,

Nhiệt kế thá»§y ngân, ẩn há»?a khôn lưá»?ng  -  07 Aug 2008
Nếu sơ ý để da tiếp xúc với thủy ngân, bị ban đ�, ngứa ngáy thì phải uống thuốc chống dị ứng (như chlorpheniramine) và bôi thuốc ngoài da vào chỗ mẩn ngứa. Ti�n Phong Online,

Ministry Warns Over Traditional Medicine  -  Jul 29, 2008
By Azlan Othman Bandar Seri Begawan - The Ministry of Health has detected an adulterant, Chlorpheniramine, in "Maajun Kuat Sakit Pinggang", Bru Direct,

Brand Names/Synonyms:
Chlorpheniramine is also known by the following brand names and/or synonyms:
Aller-Chlor; Allergican; Allergisan; Antagonate; Chlo-Amine; Chlor-Trimeton; Chlor-Trimeton Allergy; Chlor-Trimeton Repetabs; Chlor-Tripolon; Chlorate; Chloropheniramine; Chlorophenylpyridamin; Chlorophenylpyridamine; Chloropiril; Chloroprophenpyridamine; Chlorphenamine; Chlorpheniramine; Chlorpheniramine Maleate; Chlorprophenpyridamine; Clorfeniramina; Cloropiril; Dexchlorpheniramine; Dexchlorpheniramine Maleate; Efidac 24 Chlorpheniramine Maleate; Gen-Allerate; Haynon; Histadur; Kloromin; Mylaramine; Novo-Pheniram; Pediacare Allergy Formula; Phenetron; Piriton; Polaramine; Polaronil; Pyridamal 100; Telachlor; Teldrin

Drug Category:
Chlorpheniramine is categorized under the following by the FDA: Anti-allergic Agents; Antipruritics; Antihistamines; ATC:R06AB02

Dosage Forms:
Tablet (chlorpheniramine maleate)

Absorption:
Well absorbed by gastrointestinal tract

Interactions:
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Chemical IUPAC Name:
3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine





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