Ciprofloxacin HCl

This page contains recent news articles, when available, and an overview of Ciprofloxacin HCl but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Ciprofloxacin HCl (when available)

Pharmacology and use:
Ciprofloxacin, a broad-spectrum antiinfective agent of the fluoroquinolone class, is used to treat gram-negative infections, sexually transmitted diseases, mycobacterial infections, corneal ulcers, and bacterial conjunctivitis. For the treatment of Bacterial infection of Respiratory tract, UTI, Uncomplicated Cystitis in females, GI, Chronic Bacterial Prostatitis, CNS, Immuno compromised patients, Skin, Bone and Joint Infections, Uncomplicated cervical and urethral gonorrhea

Mechanism Of Action:
Ciprofloxacin has in vitro activity against a wide range of gram-negative and gram-positive organisms. Ciprofloxacin inhibits bacterial DNA gyrase, an enzyme responsible for counteracting excessive supercoiling of DNA during replication or transcription. The mechanism of action of quinolones, including ciprofloxacin, is different from that of other antimicrobial agents such as beta-lactams, macrolides, tetracyclines, or aminoglycosides; therefore, organisms resistant to these drugs may be susceptible to ciprofloxacin. There is no known cross-resistance between ciprofloxacin and other classes of antimicrobials.

News Articles on Ciprofloxacin

… . Announces FDA Approval of Ciprofloxacin HCl Ophthalmic Solution...  -  Dec 12, 2008
Akorn, Inc. (NASDAQ: AKRX) today announced that the US Food and Drug Administration has granted approval for Akorn's Abbreviated New Drug Application (ANDA) ... International Business Times

Generics makers keep new products coming.(RX/GENERICS)(Statistical …  -  Sep 17, 2007
Ranitidine HCl $217543748.22 Dr. Reddy's Lab Ciprofloxacin HCl ... Ciprofloxacin HCl $51143394.11 Actavis Elizabe Diltiazem cd $50951449.58 Barr Sprintec ... Free with registration - Chain Drug Review - AccessMyLibrary.com

United States top 250 generic pharmaceuticals by sales, and …  -  Feb 4, 2008
Bupropion HCI 279364235 41 Ranbaxy Ciprofloxacin HCl 275308736 42 ... Ciprofloxacin HCl 232571325 50 Par Ranitidine HCl 231734307 51 Mylan Zolpidem tartrate ... $20.00 - Chain Drug Review - Alacra Store

United States top 190 multisource generic drugs ranked by sales in …  -  Sep 29, 2008
Bupropion HCl XL 97 Watson Labs Hydrocodone-acetaminophen 98 Apotex Ciprofloxacin HCl 99 Apotex Paroxetine HCl 100 Teva USA Cefdinir 101 Sandoz Fentanyl 102 ... $20.00 - Chain Drug Review - Alacra Store

Article: Top 190 multisource generics by manufacturer and NDC11 …  -  Sep 29, 2008
Bupropion HCl XL 97Watson Labs Hydrocodone-acetaminophen 98Apotex Ciprofloxacin HCl 99Apotex Paroxetine HCl 100Teva USACefdinir 101Sandoz Fentanyl 102Teva ... Pay-Per-View - Chain Drug Review - HighBeam Research

Federal Register 2008 - 73 FR 51829 Publication of Guidances for …  -  Sep 5, 2008
Pseudoephedrine HCl (17) Ciprofloxacin; Ciprofloxacin HCl (18) Ciprofloxacin HCl (19) Clarithromycin (20) Darunavir Ethanolate (21) Delavirdine Mesylate ... Pay-Per-View - Federal Register 2008 - Loislaw

Article: The effect of natural sunlight on ciprofloxacin ophthalmic...  -  Oct 1, 2005
Application (ANDA) for Ciprofloxacin HCl Ophthalmic Solution USP, 0.3%. Ciprofloxacin HCl Ophthalmic Solution is indicated for the treatment ... Pay-Per-View - Journal of the Mississippi Academy of... - HighBeam Research

FDA Approvals: Proquin XR, Atacand, Pegasys  -  May 26, 2005
May 26, 2005 — The US Food and Drug Administration has approved an extended-release tablet formulation of ciprofloxacin HCl with a favorable adverse event ... Medscape

Wait for the healing power  -  May 11, 2008
And Ciprofloxacin Hcl contributes negligible revenues towards its total sales. Also, its promoter group company Nitya Laboratories Limited is in the same ... Financial Express

Depomed, Biovail Update Status of Glumetza NDA  -  Apr 13, 2005
In addition, an NDA has been submitted to the FDA for once daily Proquin(TM) (ciprofloxacin HCl extended-release tablets) for the treatment of urinary tract ... RedOrbit

United States top 200 generic drugs by retail sales in dollars and...  -  Mar 6, 2006
Furosemide Oral 241477 -0.7 35 Triamterene w/HCTZ 235149 -7.5 36 Ciprofloxacin HCl 233391 -44.0 37 Clonazepam 231743 -0.1 38 Clindamycin Systemic 229206 ... $20.00 - Drug Topics - Alacra Store

United States top 200 generic pharmaceuticals by retail sales in...  -  Feb 19, 2007
Cyclobenzaprine 229226 14.4 40 Potassium Chloride 227156 -8.6 41 Nabumetone 223855 -8.0 42 Furosemide Oral 220438 -8.7 43 Ciprofloxacin HCl 219780 -5.8 ... $20.00 - Drug Topics - Alacra Store

Top 200 generic drugs by retail dollars in 2006.(COMMUNITY PRACTICE …  -  Feb 19, 2007
Cyclobenzaprine 229226 14.4 40 Potassium Chloride 227156 -8.6 41 Nabumetone 223855 -8.0 42 Furosemide Oral 220438 -8.7 43 Ciprofloxacin HCl 219780 -5.8 ... $4.95 - Drug Topics - ECNext

Top 200 generic drugs by units in 2006.(COMMUNITY PRACTICE)( …  -  Mar 5, 2007
1.1 26 Paroxetine 16242 -3.8 27 Fexofenadine 16213 324.8 28 Gabapentin 16150 6.5 29 Tramadol 15906 19.6 30 Ciprofloxacin HCl 15815 19.1 31 Acetaminophen ... $4.95 - Drug Topics - ECNext

Global top 200 generic drugs by retail sales in dollars and percent …  -  Feb 21, 2005
Lisinopril 706151 2.9 6 Metformin 653198 -11.7 7 Fluoxetine 558694 -9.6 8 Albuterol Aerosol 455549 -12.0 9 Ciprofloxacin HCl 416972 45.0 10 Amoxicillin ... $20.00 - Drug Topics - Alacra Store

Ranbaxy disappointed with FDA action  -  Sep 18, 2008
The drugs on the list include popular antibiotics, cholesterol medicines and others like Cefuroxime Axetil, Ciprofloxacin HCl, Clarithromycin, Lamivudine, ... Times of India

Wisconsin Administrative Code - RL 10.01 Definitions.  -  Jul 16, 2005
Ciprofloxacin HCl. d. Erythromycin. e. Gramicidin. em. Norfloxacin f. Penicillins. g. Polymyxin B. h. Sulfonamides. i. Tetracyclines. j. Trimethoprim. k. ... Pay-Per-View - Wisconsin Administrative Code - Loislaw

United States top 200 generic drugs by retail sales in dollars for...  -  Feb 28, 2005
981564 3 Paroxetine 924641 4 Omeprazole 811942 5 Lisinopril 706151 6 Metformin 653198 7 Fluoxetine 558694 8 Albuterol aerosol 455549 9 Ciprofloxacin HCl ... $20.00 - Chain Drug Review - Alacra Store

It is a challenge to provide low-cost medicines to consumers  -  Mar 4, 2006
A strip of 10 tablets of 500 mg each of Ciprofloxacin HCL, a widely used antibiotics costs about Rs 29 in India whereas it costs about Rs 2353 to the ... Financial Express

United States top 200 generic drugs by sales in units for 2004  -  Feb 28, 2005
127 Nitroquick 144375 128 Mirtazapine 143615 129 Ciprofloxacin HCl 142895 130 Cartia XT 139205 131 Quinine sulfate 135401 132 Clotrimazl/betamthsn. ... $20.00 - Chain Drug Review - Alacra Store

Sweden's drug authority starts ProQuin review.(Madaus Srl)(Depomed...  -  Apr 3, 2006
...say that a Marketing Authorization Application relating to the antibiotic ProQuin (ciprofloxacin HCl), an extended-release formulation similar to German ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

otic | Definition of otic | HighBeam.com: Online Dictionary  -  Jul 12, 2006
The agreement includes the recently FDA- approved Cipro(R) HC Otic (ciprofloxacin HCl and hydrocortisone otic suspension), a new anti-infective/anti ... ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

Biovail, Depomed Receive Approvable Letter from FDA for Extended- …  -  Mar 1, 2005
In addition to Glumetza(TM), an NDA has been submitted to the FDA for once daily Proquin(TM) XR (ciprofloxacin HCl extended-release tablets) for the ... $4.95 - Business Wire - ECNext

Article: Depomed.(COMPANY NEWS) - Medical Marketing & Media | …  -  Sep 1, 2006
ProQuin XR (ciprofloxacin HCl ext-rel tablets, from Depomed and Esprit) has been made available in a 3-tablet blister pack, in addition to the 50-count ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Drug makers tackle painful problems.  -  Aug 14, 2006
For its part, Depomed Inc. last year received approval from the FDA for Proquin XR, a once-daily, extended-release formulation of ciprofloxacin HCl for the ... $9.94 - Chain Drug Review - Alacra Store

Daily Dose Media Inc. Launches VitaminDaily.com and Expands in …  -  Dec 1, 2008
December 15, 2002 ; 700+ words ... ... once-daily over three days, to the conventional twice-daily dose (250 mg) of Cipro(R) (ciprofloxacin HCl), ... Pay-Per-View - Canadian Corporate News - HighBeam Research

Depomed to Present at the Wells Fargo Securities Healthcare Forum.  -  Feb 23, 2005
...has been submitted to the FDA for once daily Proquin(TM) XR (ciprofloxacin HCl extended-release tablets) for the treatment of urinary tract infections. ... Free with registration - Business Wire - AccessMyLibrary.com

Proper use of antibiotics essential for good outcomes.(Refractive...  -  Mar 15, 2005
The fluoroquinolones moxifloxacin, ciprofloxacin HCl ophthalmic ointment (Ciloxan, Alcon), and levofloxacin ophthalmic solution (Iquix, Santen) do not ... Free with registration - Ophthalmology Times - AccessMyLibrary.com

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...엘 디�?�로페낙나트륨(sodium diclofenac) △�?�방�?프티엘 염산시프로플�?사신(ciprofloxacin HCl)△한국다�?��?�찌산쿄 염산필시카�?�니드(pilsicainide HCl) 등�?�다. ... 메디팜뉴스

Depomed to Present at the Rodman & Renshaw Techvest 2nd Annual …  -  Apr 27, 2005
In addition, an NDA has been submitted to the FDA for once daily Proquin(TM) (ciprofloxacin HCl extended-release tablets) for the treatment of urinary tract ... $4.95 - Business Wire - ECNext

Depomed Announces Extended Phase II Results for Furosemide GR in …  -  May 13, 2005
In addition, an NDA has been submitted to the FDA for once daily Proquin(TM) (ciprofloxacin HCl extended-release tablets) for the treatment of urinary tract ... $4.95 - Business Wire - ECNext

Depomed Reports First Quarter 2005 Financial Results.  -  May 10, 2005
In addition, an NDA has been submitted to the FDA for once daily Proquin(TM) (ciprofloxacin HCl extended-release tablets) for the treatment of urinary tract ... $4.95 - Business Wire - ECNext

Depomed Initiates Phase II Clinical Trial for Gabapentin ER in Pain …  -  Feb 14, 2005
...has been submitted to the FDA for once daily Proquin(TM) XR (ciprofloxacin HCl extended-release tablets) for the treatment of urinary tract infections. ... $4.95 - Business Wire - ECNext

Depomed Comments on Registered Direct Offering.  -  Jan 18, 2005
...has been submitted to the FDA for once daily Proquin(TM) XR (ciprofloxacin HCl extended-release tablets) for the treatment of urinary tract infections. ... $4.95 - Business Wire - ECNext

Depomed Contracted to Develop an Extended Release Formulation of …  -  Apr 28, 2005
In addition, an NDA has been submitted to the FDA for once daily Proquin(TM) (ciprofloxacin HCl extended-release tablets) for the treatment of urinary tract ... $4.95 - Business Wire - ECNext

Brand Names/Synonyms:
Ciprofloxacin HCl is also known by the following brand names and/or synonymsBacquinor; Baycip; Bernoflox; CIPROFLOXACIN HCL; Ciflox; Cifloxin; Ciloxan; Ciprinol; Cipro; Cipro I.V.; Cipro Xl; Cipro Xr; Ciprobay; Ciprocinol; Ciprodar; Ciprofloxacin; Ciprofloxacin Base; Ciprofloxacin Dihydrochloride; Ciprofloxacin Hydrochloride; Ciprofloxacin Monohydrochloride; Ciprofloxacina; Cipromycin; Ciproquinol; Ciproxan; Ciproxin; Flociprin; Floxin; Floxin Otic; Floxin in Dextrose 5%; Ocuflox; Ofloxacin; Proquin Xr; Septicide; Velomonit

Drug Category:
Ciprofloxacin HCl is categorized under the following by the FDA: Anti-Infectives; Quinolones; ATC:J01MA02; ATC:S01AX13; ATC:S03AA07

Dosage Forms:
LIQUID; OINTMENT; SOLUTION; SUSPENSION; TABLET; TABLET (COMBINED RELEASE); TABLET (EXTENDED-RELEASE)

Absorption:
70-80%

Interactions:
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Chemical IUPAC Name:
1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1H-quinoline-3-carboxylicacid

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