Clozaril

This page contains recent news articles, when available, and an overview of Clozaril but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Clozaril
(when available)

Pharmacology and use:
Clozapine is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Clozapine is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), dopamine Type 2 (D2), 1 and 2 adrenergic, and H1 histaminergic receptors. Clozapine acts as an antagonist at other receptors, but with lower potency. Antagonism at receptors other than dopamine and 5HT2 with similar receptor affinities may explain some of the other therapeutic and side effects of Clozapine. Clozapine's antagonism of muscarinic M1-5 receptors may explain its anticholinergic effects. Clozapine's antagonism of histamine H1 receptors may explain the somnolence observed with this drug. Clozapine's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug. For the management of severely ill schizophrenic patients who fail to respond adequately to standard drug treatment for schizophrenia

Mechanism Of Action:
The mechanism of action of Clozapine, as with other drugs used to treat schizophrenia, is unknown. However, it has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of dopamine Type 2 (D2) and serotonin Type 2 (5HT2) receptor antagonism.

News Articles on Clozapine

Hushing the intruders in her brain  -  ‎Dec 29, 2009‎
She takes a combination of the antipsychotic drugs Clozaril and Thorazine and the mood stabilizer lithium. She is less violent, less depressed and behaves ... Los Angeles Times

First Snow in Iowa  -  ‎Dec 11, 2009‎
A new generation of antipsychotic medications called "atypicals" (Steve takes Clozaril twice a day) has calmed his mind and given him his life back. ... Wall Street Journal

Why Are We Drugging Our Kids?  -  ‎Dec 14, 2009‎
...and Invega marketed by Janssen, a division of J&J; Geodon by Pfizer; Abilify from Bristol-Myers Squibb; Novartis' Clozaril and Eli Lilly's Zyprexa. ... AlterNet

Nursing home doctor's prescription record questioned  -  ‎Nov 9, 2009‎
Included in those documents is the account of a Maxwell Manor psychiatric supervisor who said Reinstein heavily promoted Clozaril, the original brand name ... Chicago Breaking News - Tribune

The Dartmouth Psych Kingpin Who's Not on Lilly's List  -  ‎Oct 23, 2009‎
AstraZeneca makes Seroquel, Lilly makes Zyprexa, Janssen makes Respirdal, and Novartis makes Clozaril -- atypical antipsychotics all. ... GoozNew (blog)

Schizophrenia drug gets vote of confidence  -  Apr 2, 2006
That's not a surprise, he said, because Clozaril "was believed to be the most ... Clozaril is sold by Novartis SA, Risperdal by Janssen Pharmaceutica and ... USA Today

FDA: Antipsychotic Drugs Must Warn of Dangers to Elderly  -  Apr 12, 2005
The drugs were approved for treating schizophrenia (search) and mania, and include such brands as Abilify, Zyprexa, Seroquel, Risperdal, Clozaril and Geodon ... FOXNews

Warnings on anti-psychotic drugs made tougher in US  -  Apr 13, 2005
The move, which also applied to anti-psychotic drugs Abilify, Zyprexa, Risperdal, Clozaril and Geodon, as well as Symbyax, which is approved for the ... Telegraph.co.uk

Puzzle of antipsychotic drug weight gain solved  -  Feb 12, 2007
...developing a new generation of antipsychotic drugs that are effective but do not cause weight gain. Clozapine is sold as Clozaril by Novartis AG (NOVN.VX). Reuters

Clozaril-Risperdal Duo Lacks Efficacy Against Schizophrenia  -  Feb 1, 2006
By Jeff Minerd, 0. VANCOUVER, British Columbia, Feb. 1 - When severe schizophrenia is refractory to Clozaril (clozapine), adding Risperdal (risperidone) to ... MedPage Today

Prescribing of Antipsychotic Drugs for Children on Rise  -  Jun 9, 2006
Most of those prescriptions were for second-generation antipsychotic drugs -- such as Clozaril, Risperdal, Zyprexa, and Seroquel -- which the FDA hasn't ... FOXNews

Comments on: Bush, Karzai Look To Stabilize Afghanistan - CBS News  -  Aug 6, 2007
Let's have you titrate to Clozaril, say 30 mg bid, and work up to 100 mg bid. Go down on the Thoraine, 1/2 a tab a day until the Clozaril kicks in. ... CBS News

Psychiatric pills can pack on pounds  -  Mar 31, 2008
Lau said the anti-psychotics most likely to be associated with weight gain are: Clozaril, or clozapine; Zyprexa, Seroquel or quetiapine; Risperdal, ... United Press International

First-Time Generic Approvals: Clozaril, Ultracet, Sandostatin, Elocon  -  May 17, 2005
May 17, 2005 — The US Food and Drug Administration (FDA) has approved a first-time generic formulation and first-time 50-mg dosage strength of clozapine ... Medscape

Schizophrenia - Treatment Overview  -  Feb 5, 2008
Clozapine, such as Clozaril or Leponex, is usually considered a second-generation antipsychotic. This drug is approved in the United States for treating ... WebMD

Doctors rely too heavily on drug company data: CMA  -  Dec 19, 2007
Many atypical antipsychotics, which include drugs such as risperidone (Risperdal), quetiapine (Seroquel), olanzapine (Zyprexa) and clozapine (Clozaril), ... CBC.ca

NEED ADVICE: low white blood cell count with CLOZARIL  -  Jul 14, 2007
This is my first post.I have bipolar disorder,not schizophrenia,but am posting my question here because I don't know too many bipolars who take clozaril. ... HealthCentral.com

Wisconsin Case Law - STATE v. STANLEY, 2009 WI App 1  -  Nov 13, 2008
His medication was then changed from Prolixin to Clozaril, and he has remained on ... Dr. Castillo testified that the dosage of Clozaril which Stanley is ... Pay-Per-View - Wisconsin Case Law - Loislaw

Dementia patients warned off new drugs  -  Jun 16, 2005
The warning relates to four drugs - olanzapine (Zyprexa), risperidone (Risperdal), quetiapine (Seroquel) and clozapine (Clozaril) - and was issued yesterday ... Pay-Per-View - Toronto Star - ProQuest Archiver

Clozaril Monitoring Schedule Modified to Include ANC Reporting  -  Jan 17, 2006
Jan. 17, 2006 — The US Food and Drug Administration (FDA) and Novartis Pharmaceutical Corporation have notified healthcare professionals via letter ... Medscape

FDA Safety Labeling Changes: Cefuroxime, Zocor, Clozaril  -  Aug 31, 2005
Aug. 31, 2005 -- The US Food and Drug Administration (FDA) approved in May and June revisions to safety labeling to advise that oral vancomycin is ... Medscape

Novartis's drug Clozaril received a label change updating the "Other ...  -  Dec 1, 2008
Novartis's drug Clozaril received a label change updating the "Other Events Observed During the Premarketing Evaluation". Pay-Per-View - Medical Marketing & Media - HighBeam Research

Clozapine (generic): Clozaril (brand).(YOUR MEDICATION …  -  Jul 1, 2005
COMMON USAGE: Clozapine is indicated for treatment-resistant psychosis and for suicidal behavior in patients with schizophrenia or schizoaffective disorder ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

FDA Calls for Safety Plans for 25 Agents  -  Mar 28, 2008
The list as published in the Federal Register includes the multiple myeloma medication thalidomide (Thalomid), the anti-psychotic clozapine (Clozaril), ... MedPage Today

Medications for Schizophrenia  -  Dec 10, 2006
The first of these, clozapine (Clozaril), has been shown to be more effective than other antipsychotics, although the possibility of severe side effects ... PsychCentral.com

Using clozapine in agitated dementia patients.(INPATIENT PRACTICE)( …  -  Nov 1, 2007
According to one recent article, however, clozapine (Clozaril) may produce significant improvement in cases in which other antipsychotics, antidepressants, ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Tramadol (Systemic).(Drug overview)  -  May 1, 2006
Neuroleptic drugs (antipsychotic drugs) (chlorpromazine [eg, Thorazine], clozapine [eg, Clozaril], haloperidol [eg, Haldol], loxapine [eg, Loxitane]) or ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Code of New Hampshire Rules - He-M 426.07 Medication-Related …  -  Aug 12, 2005
...(g) Comprehensive medication service for clozapine/clozaril management shall be a covered service provided by a physician, physician assistant, ARNP, ... Pay-Per-View - Code of New Hampshire Rules - Loislaw

Ivax to sell new dosage on schizophrenia drug  -  Apr 26, 2005
Clozapine is a generic form of Clozaril, a schizophrenia drug marketed by Novartis. ... Last year's US sales for Clozaril and its generic were $182 million, ... South Florida Business Journal

Should kids get these drugs?  -  May 11, 2008
They're sold under the names Zyprexa, Geodon, Risperdal, Abilify, Seroquel, Clozaril and Invega. The drugs belong to a relatively new class of ... $2.95 - News Tribune - NewsBank

MGH Docs Link Diabetes to Anti-Psychotic Meds  -  Jan 4, 2005
Clozapine and olanzapine are sold under the brand names Clozaril and Zyprexa, respectively. "Clinicians need to recognize there is a risk and inform ... RedOrbit

CATIE Phase 2: Clozapine Most Effective, Followed by Risperidone, …  -  Jun 1, 2006
Another 99 patients who had discontinued treatment agreed to take clozapine (Clozaril), which is known to be more effective than other second-generation ... Pay-Per-View - Psychiatric Times - Factiva, from Dow Jones

… Administrative Rules - APPENDIX E Clozaril Enrollment Information...  -  Aug 9, 2005
APPENDIX E Clozaril Enrollment Information Form, repealed, 31 SDR 214, SEE: § 67:16:02:05.04 Source: 18 SDR 50, effective September 15, 1991; 26 SDR 168, ... Pay-Per-View - South Dakota Administrative Rules - Loislaw

… Dakota Administrative Rules - 67:16:14:06.08. Coverage limits —...  -  Aug 9, 2005
Coverage limits — Clozaril. Repealed. it is discontinued or suspended. Source: 18 SDR 50, effective September 15, 1991; repealed, 31 SDR 214, effective July ... Pay-Per-View - South Dakota Administrative Rules - Loislaw

… Rules - 67:16:02:05.05. Requirements for monitoring clozaril therap...  -  Aug 9, 2005
Requirements for monitoring clozaril therapy. Repealed. Source: 18 SDR 50, effective September 15, 1991; repealed, 31 SDR 214, effective July 6, 2005. ... Pay-Per-View - South Dakota Administrative Rules - Loislaw

Study affirms effectiveness of schizophrenia drug  -  Mar 31, 2006
That's not a surprise, he said, because Clozaril "was believed to be the most ... Clozaril is sold by Novartis SA, Risperdal by Janssen Pharmaceutica and ... $2.95 - Associated Press Archive - NewsBank

South Dakota Administrative Rules - 67:16:02:05.03. Clozaril therapy ...  -  Aug 9, 2005
67:16:02:05.03 . Clozaril therapy — Limits. Repealed. Source: 18 SDR 50, effective September 15, 1991; repealed, 31 SDR 214, effective July 6, 2005. ... Pay-Per-View - South Dakota Administrative Rules - Loislaw

… - 67:16:02:05.06. Requirements when clozaril therapy discontinued...  -  Aug 9, 2005
Requirements when clozaril therapy discontinued or suspended. Repealed. Source: 18 SDR 50, effective September 15, 1991; repealed, 31 SDR 214, ... Pay-Per-View - South Dakota Administrative Rules - Loislaw

FDA calls for warnings on atypicals used for dementia.(News)  -  May 1, 2005
...clozapine (Clozaril), and ziprasidone (Geodon). The FDA said Symbyax, a combination of olanzapine and fluoxetine, will also get the warning. ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Diabetes risk does vary with choice of antipsychotic drug.  -  Jan 14, 2005
Patients with schizophrenia who are taking either clozapine (Clozaril) or olanzapine (Zyprexa) may be at higher risk of diabetes than patients taking other ... Free with registration - GP - AccessMyLibrary.com

Lawsuits filed over fatal overdose - Patient died at Community after...  -  Apr 16, 2007
13 and 14 Gremminger was given 300 milligrams of Clozaril. Spitz wrote that the combination of both drugs was dangerous. The doses were given despite a note ... $2.95 - Fresno Bee - NewsBank

New warning issued  -  Apr 19, 2005
The warning affects Eli Lilly's Zyprexa and Symbyax, AstraZeneca Pharmaceuticals's Seroquel, Johnson & Johnson's Risperdal, Novartis's Clozaril, ... Pay-Per-View - Pharmacy News - Factiva, from Dow Jones

More restructuring.(Tysabri)(Brief Article)  -  Apr 18, 2005
The drugs affected are Eli Lily's Zyprexa and Symbyax, AstraZeneca's Seroquel, Johnson & Johnson's Risperdal, Novartis's Clozaril, Pfizer's Geodon, ... $4.95 - Chemistry and Industry - ECNext

Article: FDA: Antidepressants Pose Risk to Teens - AP Online |...  -  Dec 5, 2006
Article: FDA approves Clozaril to reduce the risk of ... ... Article: FDA Committee Recommends Approval for Clozaril(R) to Treat ... ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Code of New Hampshire Rules - He-W 530.04 Co-Payments.  -  Aug 12, 2005
...in accordance with He-W 530.02(b); (2) For family planning products that require a prescription; and (3) For Clozaril (Clozapine) prescriptions. Source. ... Pay-Per-View - Code of New Hampshire Rules - Loislaw

New warning on antipsychotic drugs used to treat older people.(Updates...  -  Jul 1, 2005
The drugs, which include Abilify (aripiprazole), Zyprexa (olanzapine), Seroquel (quetiapine), Risperdal (risperidone), Clozaril (clozapine), ... $4.95 - FDA Consumer - ECNext

Article: Effects of Adult Antidepressants Mixed - AP Online |...  -  Dec 5, 2006
Article: FDA approves Clozaril to reduce the risk of ... ... Article: FDA Committee Recommends Approval for Clozaril(R) to Treat ... ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

After decades of darkness, light  -  Jan 21, 2007
He says that before Clozaril, the drugs used to treat mental illness ... Clozaril controls the thought disorder. It has turned some people's lives around. ... Boston Globe

Article: FDA: Antidepressants Dangerous for Teens - AP Online | …  -  Dec 5, 2006
Article: FDA approves Clozaril to reduce the risk of ... ... Article: FDA Committee Recommends Approval for Clozaril(R) to Treat ... ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Metabolic syndrome common with clozapine.(Adult Psychiatry) | Article...  -  Oct 1, 2008
All patients were taking clozapine (Clozaril), with a mean duration of 9 years of ... The choice comes down to augmenting clozapine (Clozaril) with ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Article: Effects of Adult Antidepressants Mixed - AP Online |...  -  Dec 5, 2006
Article: FDA approves Clozaril to reduce the risk of ... ... Article: FDA Committee Recommends Approval for Clozaril(R) to Treat ... ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Could he have been saved?: Death of man with schizophrenia points out...  -  Dec 17, 2006
For the last several years, he was treated with Clozaril. ... "I almost died when I went off Clozaril years ago," said Bruce Bjorum, 52, ... Free with registration - Milwaukee Journal Sentinel - AccessMyLibrary.com

Second-generation antipsychotics offer mixed results; finding the...  -  Jun 1, 2007
Clozaril is effective in schizophrenia patients who do not respond to other ... "Some second-generation drugs, particularly Clozaril and Zyprexa, ... Free with registration - Managed Healthcare Executive - AccessMyLibrary.com

Big Pharma Baffled Again  -  Apr 3, 2006
One study of 99 patients in the second round included Clozaril from Novartis, ... The median time patients stayed with Clozaril was 10.5 months, ... TheStreet.com - TheStreet.com (subscription)

Many treatments available for clozapine-related drooling.(EVIDENCE- …  -  Nov 1, 2008
All patients were taking clozapine (Clozaril), with a mean duration of 9 ... mood stabilizer, than among those taking clozapine monotherapy (83% vs 7%). ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

HE DEDICATED HIS LIFE TO MAKE LIFE BETTER FOR THE MENTALLY …  -  Jul 22, 2007
Clozaril "changed peoples' lives dramatically," says Sheryl Breetz, ... It was Clozaril, sold as Clozapine, and though it had been used in Europe, ... Pay-Per-View - Hartford Courant - ProQuest Archiver

Clozapine 'wins again' in phase II of CATIE.(drug usage)(clinical...  -  May 1, 2006
According to one recent article, however, clozapine (Clozaril) may produce ... All patients were taking clozapine (Clozaril), with a mean duration of ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

FDA approves two monitoring changes for clozapine patients.(Food and ...  -  Sep 1, 2005
All the WBC data have been entered into the Clozaril National Registry and have been ... The revised Clozaril label is available on the FDA's Web site at: ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Eisai Inc.(MANUFACTURERS) | Article from Medical Marketing & Media | ...  -  Sep 1, 2008
Article: Managing a product under attack: a firsthand report on Clozaril. ... ... Honigfeld, Ph.D., associate director, product marketing, Clozaril ... the ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

I pazienti con schizofrenia e disturbo schizoaffettivo trattati con...  -  Aug 2, 2006
...disturbo schizoaffettivo che hanno ricevuto Clozapina ( Clozaril/Leponex ) e un gruppo partecipante al National Health and Nutrition Examination Survey ... XagenaSalute

L'aggiunta di Risperidone alla Clozapina nei pazienti con grave …  -  Feb 20, 2006
Risperidone Enhancement ) hanno esaminato i pazienti affetti da schizofrenia e con scarsa risposta al trattamento con Clozapina ( Clozaril/Leponex ). ... XagenaSalute

Zyprexa Edges Four Other Agents With Modest Benefit for Schizophrenia  -  Sep 19, 2005
The other drug, Clozaril (clozapine) was not included in the CATIE trial and Dr. ... So, Dr. Freedman wrote, Zyprexa and Clozaril although effective have ... MedPage Today

Press Release: Oridion Launches its Fully Integrated Remote Monitoring...  -  Oct 15, 2007
Article: Sandoz discussing changes for Clozaril monitoring ... ... Article: Unique Clozaril National Registry Paramount to Patient ... ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Boston Scientific Releases Remote Monitoring Data from...  -  Sep 14, 2007
Article: CAREMARK ANNOUNCES AGREEMENT TO SELL CLOZARIL PATIENT ... ... The Clozaril patient management business involves managing the care ... executive ... Pay-Per-View - PR Newswire - HighBeam Research

FDA approves changes to clozapine blood monitoring.(Rx)  -  Oct 1, 2005
Novartis, which manufactures Clozaril, the trade formulation, is planning to send out ... The revised Clozaril Label is available on the FDA's Web site at: ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Drug Companies Still Peddling Risperdal & Zyprexa  -  Jun 19, 2006
None of the 6 drugs including Clozaril, Risperdal, Zyprexa, Seroquel, ... The less popular atypical, Clozaril, approved by the FDA on April 28, ... scoop.co.nz

New antipsychotic drugs carry risks for children  -  May 2, 2006
None of the six drugs — Clozaril, Risperdal, Zyprexa, Seroquel, Abilify and Geodon — is ... Also, neither Clozaril, which is rarely used, nor Abilify, ... USA Today

Drugs not enough for mentally ill, study finds  -  Mar 1, 2007
She said her daughter, Kristen, started and stopped about five medicines before finding Clozaril about 10 years ago. It was one of the first "next ... News & Observer

The FDA said it examined the wrong factory when assessing the safety...  -  Mar 1, 2008
Article: Managing a product under attack: a firsthand report on Clozaril. ... Medical Marketing & Media; September 20, 1991 ; 700+ words ... ... disorder ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Special to CNN.com  -  Feb 6, 2006
These antipsychotics include clozapine (Clozaril), risperidone (Risperdal), ... For this reason, people who take Clozaril, Risperdal, Zyprexa, Seroquel, ... CNN

Patients With Treatment-Resistant Schizophrenia Get Good News Today …  -  May 23, 2005
In this study, FazaClo was administered without any liquids and Clozaril was ... *Clozaril(R) is a registered trademark of Novartis Pharmaceutical Corporation. RedOrbit

Molecular Stewardship: advocate: Paul Duffy.(Leading Indicators: …  -  Jun 1, 2005
Back in June 2003, Novartis reallocated the promotional dollars behind Clozaril (clozapine), a product used for treatment-resistant schizophrenia that faced ... Free with registration - Pharmaceutical Executive - AccessMyLibrary.com

The experience of bipolar disorder: a personal perspective on the...  -  Jun 10, 2005
Clozaril ® (clozapine), the medication of last resort, turned things around. ... My parents together went to Clozaril support groups and family therapy. ... Nature.com

lupus A transplant rejectio ...  -  Dec 6, 2005
Vesprin, Taractan, Haldol, Loxitane, Moban, Orap and Navane and the atypical drugs Abilify, Clozaril, Zyprexa, Seroquel, Risperdal and Geodon. ... Pay-Per-View - Washington Post - ProQuest Archiver

All antipsychotic drugs are risky, study says  -  Feb 28, 2007
A fourth in this class, clozapine (Clozaril), was not studied. But because it is in the same family, Health Canada included it in its warning about the ... Pay-Per-View - The Record - ProQuest Archiver

Article: Metabolic risks of atypicals dissected.(Adult Psychiatry) -...  -  Apr 1, 2005
Clozapine (Clozaril) and olanzapine (Zyprexa) cause the most ... Read all of this article with a FREE trial. Related newspaper, magazine, and journal ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

FDA Grants Monthly WBC Monitoring for FazaClo(R) (clozapine, USP).  -  May 18, 2005
In this study, FazaClo was administered without any liquids and Clozaril was ... *Clozaril(R) is a registered trademark of Novartis Pharmaceutical Corporation. $4.95 - PR Newswire - ECNext

Article: Cara's pals really take the biscuit for caring; FUNDRAISERS:...  -  Nov 15, 2006
WEEKLY BLOOD MONITORING WILL REMAIN REQUIREMENT FOR CLOZARIL ... receiving Clozaril therapy have weekly blood monitoring, as required by the FDA, ... Pay-Per-View - Coventry Evening Telegraph - HighBeam Research

Ask the Doc  -  Jun 13, 2006
Recently the doctor suggested that he should try Clozaril. He has tried Seroquel for four months in 2002 ... My concern is whether Clozaril can help him. ... Pay-Per-View - TODAY - Factiva, from Dow Jones

Parkinson's Disease: Other Medical Concerns: Mental Illness  -  Jun 1, 2005
Medications such as Zyprexa, Seroquel and Clozaril can effectively control ... Clozaril is the least likely to worsen Parkinson's symptoms; but, ... WebMD

Drug discovery: Playing dirty  -  Oct 13, 2005
The schizophrenia drug Clozaril (clozapine), for example, works because it targets a large number of proteins, says Bryan Roth, a biochemist at Case Western ... Nature.com

Antipsychotic drugs are doing harm  -  Mar 16, 2008
Known as atypical antipsychotics, drugs such as Clozaril, Zyprexa and Risperdal largely replaced older medications such as Thorazine, Haldol and Prolixin. ... Pay-Per-View - Register-Guard - ProQuest Archiver

Another drug, another red flag; New anti-psychotics linked to...  -  Apr 16, 2005
Doctors are well aware that patients taking Clozaril, for instance, must take weekly blood tests because the drug can cause a fatal blood disorder. ... Pay-Per-View - Toronto Star - Factiva, from Dow Jones

NATION & WORLD BRIEFING  -  Apr 1, 2006
However, Clozaril is under-used because of side effects, including a loss of white blood cells and a potentially fatal inflammation of heart muscle. ... $2.95 - St. Paul Pioneer Press - NewsBank

BUSINESS BRIEFING  -  Dec 20, 2005
Clozapine is the generic equivalent of Clozaril, which is marketed by Novartis and ... According to industry figures, sales for Clozaril and its generic ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

Richardson Independent School Dist. v. Michael Z., No. 3:05-CV-535-M...  -  Apr 22, 2008
...[43], The second category of tests-blood diagnostics- was administered while Leah was taking Clozaril and Lithium. The tests, performed between August 20 ... $2.95 - U.S. District Court, Northern District... - VersusLaw

Psychiatrists encouraged to stop underprescribing clozapine.(Adult …  -  Oct 1, 2007
..."If a clinician is uncomfortable administering clozapine (Clozaril), that should not stop a patient from getting it, given its superior effectiveness," he ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Ivax gets approval for schizophrenia tablet  -  Dec 19, 2005
US sales for Clozaril and clozapine were $135.5 million for the 12 months ending on Sept. 30, according to Ivax. Its generic version accounted for 53 ... South Florida Business Journal

Risperidone (Systemic).  -  Jul 28, 2005
Tegretol) or Clozapine (eg, Clozaril) or Fluoxetine (eg, Prozac, Sarafem) or Paroxetine (eg, Paxil) -- These medicines may affect the blood levels of ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Worried about the risk of atypical antipsychotics for your child? …  -  Oct 1, 2006
In the mid-to-late 1990s, we began to see an increasing number of prescriptions of Risperdal, Zyprexa, Geodon, and Clozaril. In our work thirty years ago in ... Free with registration - Townsend Letter: The Examiner of... - AccessMyLibrary.com

Label-printing software eases management of patients on clozapine  -  Feb 22, 2005
Novartis, manufacturers of the proprietary brand Clozaril, provide both the analysis and an Internet Patient Monitoring System (IPMS) required to track and ... bjhcim

Schizophrenia Treatment  -  Apr 10, 2006
Clozapine (also known as clozaril) has been shown to be more effective than many newer antipsychotics as well. Antipsychotic medications help to normalize ... PsychCentral.com

Antipsychotic Drugs Boost Stroke Risk  -  Aug 29, 2008
Atypical antipsychotics include drugs such as Abilify, Clozaril and Zyprexa. Typical antipsychotics include Thorazine, Haldol and Clopixol. ... Washington Post

Psychiatrists encouraged to stop underprescribing clozapine.(Adult …  -  Oct 1, 2007
..."If a clinician is uncomfortable administering clozapine (Clozaril), that should not stop a patient from getting it, given its superior effectiveness," he ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

In re Michael L., No. 2005-08748 (NYApp.Div. 02/14/2006)  -  Feb 14, 2006
Nine months after a similar petition was denied, the State sought another order permitting it to administer Clozaril, an anti-psychotic medicine, ... $2.95 - New York State Courts - VersusLaw

Article: Schizophrenia Drug Gets Vote of Confidence - AP Online | …  -  Apr 1, 2006
That's not a surprise, he said, because Clozaril "was believed ... Read all of this article with a FREE trial. Related newspaper, magazine, and journal ... Pay-Per-View - AP Online - HighBeam Research

FDA Issues Warning on Drug Use by Elderly | Article from AP Online | ...  -  Apr 11, 2005
The drugs were approved for treating schizophrenia and mania, and include such brands as Abilify, Zyprexa, Seroquel, Risperdal, Clozaril and Geodon. ... Pay-Per-View - AP Online - HighBeam Research

Worried about the risk of atypical antipsychotics for your child? …  -  Oct 1, 2006
In the mid-to-late 1990s, we began to see an increasing number of prescriptions of Risperdal, Zyprexa, Geodon, and Clozaril. In our work thirty years ago in ... Pay-Per-View - Townsend Letter: The Examiner of... - HighBeam Research

FDA clears more products for market.  -  Jun 6, 2005
...s Clozaril), a schizophrenia treatment; 600- and 800-mg gabapentin tablets (the generic version ... It is the generic equivalent to Novartis AG's Clozaril. ... $9.94 - Chain Drug Review - Alacra Store

J&J Schizophrenia Drug Wins Federal OK | Article from AP Online | …  -  Dec 20, 2006
Novartis' Clozaril, Janssen' s Risperdal and AstraZeneca's Seroquel ... lilly.com U.S. Food and Drug Administration: www.fda.gov ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Lilly and Novartis antipsychotics keep patients on treatment longer  -  Apr 7, 2005
Findings from three studies show that schizophrenia patients taking atypical antipsychotics such as Eli Lilly's Zyprexa or Novartis' Clozaril stayed on ... Pay-Per-View - Datamonitor News and Comment - Factiva, from Dow Jones

The patient's page.(side-effects of Warfarin)(methods for the...  -  Jul 1, 2005
Antipsychotic medications, such as Clozaril (clozapine), ... Weight gain: Clozaril, Zyprexa, and Seroquel are the most likely to cause weight gain, ... $4.95 - Southern Medical Journal - ECNext

North Carolina Administrative Code - 10A NCAC 27A .0212 CLOZAPINE  -  Aug 1, 2005
10A NCAC 27A .0212 CLOZAPINE (a) The Division shall administer a program for the reimbursement of area programs for the purchase of the drug Clozaril for ... Pay-Per-View - North Carolina Administrative Code - Loislaw

SOFTWARE DONATED.(Business) | Article from The Cincinnati Post ( …  -  May 27, 2005
Article: CLOZARIL WORKS, BUT DOCTORS UNSURE WHY.(LIVING) The Cincinnati Post (Cincinnati, OH); April 1, 1996 ; 637 words ... ... said Dr. Walter Smitson, ... Pay-Per-View - Cincinnati Post - HighBeam Research

Report: Zyprexa maker minimized possible risks  -  Dec 17, 2006
The drugs, which also are the most widely used medications for aggressive, disruptive children, also include Risperdal, Seroquel, Clozaril, Geodon and ... USA Today

Brand Names/Synonyms:
Clozaril is also known by the following brand names and/or synonymsAsaleptin; Clozapin; Clozapine; Clozaril; Fazaclo ODT; HF-1854; Iprox; Leponex; Lepotex; W-801

Drug Category:
Clozaril is categorized under the following by the FDA: Antipsychotics; Antipsychotics; ATC:N05AH02

Dosage Forms:
TABLET

Absorption:
rapid and almost complete

Interactions:
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Chemical IUPAC Name:
Not Available





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