Crestor

This page contains recent news articles, when available, and an overview of Crestor but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Crestor
(when available)

Pharmacology and use:
Rosuvastatin is an antilipemic agent and a competitive HMG-CoA reductase inhibitor effective in lowering LDL cholesterol and triglycerides. It is used to treat primary hypercholesterolemia and mixed dyslipidemia (Fredrickson types IIa and IIb). For the treatment of pure hypercholesterolaemia and mxed hyperlipidaemia

Mechanism Of Action:
Rosuvastatin selectively and competitively inhibits the hepatic enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. As HMG-CoA reductase is responsible for converting HMG-CoA to mevalonate, this results in a decrease in mevalonate, a precursor of cholesterol, and a subsequent decrease in hepatic cholesterol levels and increase in uptake of LDL cholesterol.

News Articles on Rosuvastatin

Lilly's research chief to retire in February  -  14 Nov 2009
...based in London, whose best-selling products include Crestor for cholesterol, Seroquel for schizophrenia and Symbicort for asthma. ... Indianapolis Star

AstraZeneca to weigh buyback in January  -  ‎Nov 10, 2009‎
It also faces a patent challenge from generic drugmakers to its new blockbuster cholesterol drug Crestor, which could prematurely cut off revenues from a ... Reuters

AstraZeneca quarterly earns up 22 percent  -  ‎Oct 29, 2009‎
Revenue rose 5.5 percent to $8.2 billion, supported by strong demand for its cholesterol drug Crestor alongside sales of the H1N1 vaccine and reduced ... The Associated Press

Statins may reduce severe H1N1 death risk  -  ‎Nov 13, 2009‎
One group will receive the statin rosuvastatin, Crestor, every day for the duration of their hospital stay, and the other group will receive a placebo. ... United Press International

Drugmaker AstraZeneca cutting its US sales force  -  ‎Oct 19, 2009‎
The maker of cholesterol pill Crestor and anti-psychotic drug Seroquel is asking interested sales representatives to identify themselves. ... The Associated Press

U.S. FDA advisory meetings through Dec. 18  -  ‎Nov 2, 2009‎
L) for Crestor. The proposed use of Crestor in this application is primary prevention of cardiovascular disease based on the results of JUPITER. ... Reuters

STOCKS NEWS EUROPE-UK pharmas rise; BarCap starts coverage  -  ‎Nov 12, 2009‎
On AstraZeneca it says there is a strong case in the Crestor US patent trial, with the potential for a positive summary judgement hearing before year-end. ... Reuters UK

Simcere Pharmaceutical Group to Acquire China Manufacturing License for ...  -  ‎Nov 9, 2009‎
Rosuvastatin was first marketed by Astrazeneca as Crestor in 2003 and is an effective statin to treat high cholesterol and related conditions. ... CNNMoney.com (press release)

ASK DR. H: Breast lump linked to Zocor?  -  ‎Nov 11, 2009‎
An interesting observation is that switching a patient from one statin drug to another (eg, Zocor or Crestor to Lipitor) may reverse the gynecomastia. ... Atlanta Journal Constitution

AstraZeneca on Crestor crusade  -  ‎Nov 8, 2009‎
AstraZeneca is preparing for the start of a legal battle to protect the patent on Crestor, one of its most profitable drugs. ... This is Money

Low cholesterol may prevent some prostate cancers  -  ‎Nov 3, 2009‎
Doctors say it is premature to advise men to take statin drugs like Lipitor or Crestor in the hope of preventing prostate cancer, but these medicines are ... The Associated Press

Crestor Reduces Lipids Better Than Pravachol in People With HIV  -  ‎Oct 27, 2009‎
Statins (or HMG-CoA reductase inhibitors) are frequently prescribed to treat elevated LDL—notably Crestor and Pravachol, because they are the least likely ... AIDSmeds.com HIV/AIDS Treatment News

Lower Cholesterol Lessens Risk Of Some Cancers  -  ‎Nov 10, 2009‎
However, researchers were not sure how many men participating in the study were taking statin drugs like Lipitor, Zocor or Crestor. ... Visit Bulgaria

CORONA analysis reopens door for statins in heart failure  -  ‎Nov 3, 2009‎
...the efficacy of rosuvastatin (Crestor, AstraZeneca) was inversely related to levels of amino-terminal pro-brain natriuretic peptide (NT-proBNP), ... TheHeart.Org

Gary Wenzel Named President TBWA\WorldHealth  -  ‎Nov 12, 2009‎
His work on those two brands was instrumental in AZ awarding Crestor to Saatchi where Steve created the Mandy Patinkin campaign. Steve began his career at ... CNNMoney.com (press release)

Cholesterol Drug Crestor Approved for Children  -  ‎Oct 27, 2009‎
The US Food and Drug Administration (FDA) has approved the use of Crestor, generic name rosuvastatin, for lowering cholesterol for children and teens with a ... eMaxHealth

Buy On-line - crestor side effects  -  ‎Oct 31, 2009‎
Buy crestor lawyer to discuss the FDA not to buy Organic. Crestor rebate. Drug information contained on this one. Risk of myopathy and rhabdomyolysis among ... Newstalk ZB

Statins for Lowering Cholesterol Linked to Increased Diabetes Risks  -  ‎Oct 23, 2009‎
Lipitor, Crestor and other brands of statins taken by millions of people to lower cholesterol do not reduce the risks of diabetes and may in fact slightly ... Attorney at Law

Cholesterol-Lowering Statin May Diminish Flu Deaths  -  ‎Oct 30, 2009‎
...were taking statins containing Crestor, Lescol, Lipitor, Mevacor, Pravachol, and Zocor, are less likely to die than those who weren't taking the drugs. ... TopNews New Zealand

People's Pharmacy: a cholesterol dilemma  -  ‎Oct 25, 2009‎
A: In searching the medical literature, we found an article in Drug Safety (July 2009) confirming that some statin-type drugs (Crestor, Lipitor, ... Houston Chronicle

Red Yeast Rice To The Rescue  -  ‎Nov 11, 2009‎
...liver damage which are caused by the prescription high cholesterol medicines which are grouped as statins; namely the Lipitor, Crestor, Simplilcor, ... Barnacle

What You Don't Know May Cost You When It Comes To Prescriptions  -  ‎Nov 4, 2009‎
Lipitor, Zocor, Pravacol and Crestor are all statins used to control cholesterol. But Lipitor and Crestor don't have generics. You need to ask for the ones ... WPXI.com

Waning Cost Cuts Help Pfizer's 3Q  -  ‎Oct 20, 2009‎
...as the drug continues to lose market share to cheaper generic versions of Zocor and the potentially strong competitor Crestor from AstraZeneca AZN . ... Morningstar.ca

SCR: To Acquire Manufacturing License in China for Rosuvastatin (Crestor)  -  ‎Nov 9, 2009‎
Rosuvastatin was first marketed by Astrazeneca as Crestor in 2003 and is an effective statin to treat high cholesterol and related conditions. ... Trading Markets (press release)

Rx copay cards: There's an easier way  -  ‎Nov 3, 2009‎
In my pharmacy, the most frequently used copay cards are for Lipitor, Nexium, and Crestor. Then there are the checks/coupons for Advair, Vesicare, ... ModernMedicine

Improvements to CV risk factors, but magnitude very low  -  ‎Oct 28, 2009‎
The investigators pointed out several times that the amount of hsCRP decrease seen with lorcaserin was equivalent to what was shown by Crestor in the ... Gerson Lehrman Group

A Little Distracted, Are You, Merck?  -  ‎Nov 3, 2009‎
...its Zetia and Zocor, and Abbott Labs (NYSE: ABT) and AstraZeneca (NYSE: AZN) are working on a combination of their TriLipix and Crestor, respectively. ... Motley Fool

AstraZeneca withdraws filings for lung cancer drug  -  ‎Nov 2, 2009‎
Seroquel (quetiapine) for schizophrenia and cholesterol-lowerer Crestor (rosuvastatin). Just ahead of the marketing submissions, analysts at Jefferies ... Pharmafocus

Maintaining Healthy Cholesterol Levels May Lower Risk of Prostate Cancer  -  ‎Nov 5, 2009‎
...men in the study who were taking cholesterol-lowering medications such as statin drugs, which include such name brands as Lipitor, Zocor, and Crestor. ... HealthNews

Business news in brief  -  ‎Oct 20, 2009‎
The maker of cholesterol pill Crestor is asking interested sales representatives - among 5500 of them in the United States - to identify themselves. ... Philadelphia Inquirer

AstraZeneca PLC third quarter and nine months financial results 2009  -  ‎Oct 29, 2009‎
...underlying business performance driven particularly by Crestor, with sales up 30% in the quarter, and Symbicort, with sales in the third quarter up 22%. ... DeHavilland (press release) (subscription)

Another Notch in the Bottle for Statin Drugs: They Decrease Gallstones ...  -  ‎Nov 11, 2009‎
Consumer Reports' chief medical adviser blogs about recent study showing a cholesterol lowering drug - Crestor - cut the risk of heart attack and stroke, ... SeniorJournal.com

Money Briefs  -  ‎Oct 20, 2009‎
Spokesman Tony Jewell says AstraZeneca, maker of the cholesterol pill Crestor and anti-psychotic drug Seroquel, will know the full scope of the sales force ... Worcester Telegram

Cholesterol drug sales set to double  -  ‎Nov 6, 2009‎
Other than Lipitor, statins also include other top grossers like AstraZeneca's Crestor, Merck's Zocor and Mevacor, amongst others. Daily News & Analysis

Prescription assistance program rolls into Canton  -  ‎Oct 21, 2009‎
His prescription list includes Crestor, Tegretol, and Claritin-D. To date, the “Help is Here Express� has traveled to 3000 cities in every state and helped ... Canton Repository

Protecting patients during influenza season especially important this year  -  ‎Nov 2, 2009‎
Bernard and colleagues are examining the utility of rosuvastatin (Crestor, AstraZeneca) vs. placebo in hospital mortality to 28 days, or time to resolution ... Cardiology Today

Judge refuses secondhand smoke testimony in South Dakota smoking ban lawsuit  -  ‎Nov 3, 2009‎
Dallas Morning News http://ff.im/aWv2e VerveHealth Verve Health Statins may prevent flu deaths: Cholesterol-lowering drugs such as Zocor, Crestor, ... Gaea Times

AZ-BMS launch Onglyza in Europe  -  ‎Oct 19, 2009‎
Also in the US, the FDA has approved AstraZeneca's Crestor (rosuvastatin calcium) for use in children ages 10-17 with genetic disease heterozygous familial ... Pharmafocus

Naturopaths want the ability to prescribe  -  ‎Oct 23, 2009‎
..."This is not about ND s suddenly turning around and writing scripts for Crestor, because as you're pointing out, we don't need to. ... Standard Freeholder

AstraZeneca relève à nouveau sa prévision de résultat annuel  -  ‎Oct 29, 2009‎
2009 pour le deuxième trimestre d'affilée, en raison de la forte demande pour son vaccin contre la grippe A(H1N1) et pour son anti-cholestérol Crestor. ... nouvelobs.com

Simcere Pharma收购中国的Rosuvastatin制造许å?¯  -  ‎Nov 10, 2009‎
...æ ¹æ?®å??议,Simcere Pharmaå°†é€?过入股Tianda,以å?ŠTianda转移特定技术给Simcere,完æˆ?收购制造许å?¯ã€‚2003å¹´Astrazeneca最åˆ?以Crestorå??义行销Rosuvastatin。 ... 凤凰网

FDA aprova uso de Crestor® em doentes pediátricos  -  ‎Oct 19, 2009‎
A AstraZeneca anunciou que a FDA (Food and Drug Administration) aprovou o Crestor® (rosuvastatina cálcica) para uso em crianças dos 10 aos 17 anos com ... RCM Pharma

Crestorâ„¢ одобрен в СШÐ? длÑ? применениÑ? у детей  -  ‎Oct 20, 2009‎
что Управление по контролю за пищевыми продуктами и лекарÑ?твенными Ñ?редÑ?твами СШÐ? (Food and Drug Administration) одобрило препарат Crestorâ„¢/КреÑ?тор ... Аптека online

AUDIO: LAS MEDICINAS GENÉRICAS SON ECONÓMICAS PERO ES IMPORTANTE SABER QUE SU ...  -  ‎Oct 29, 2009‎
CRESTOR, JUNTO CON LA DIETA, SE INDICA PARA RETRASAR LA EVOLUCIÓN DE LA ATEROESCLEROSIS COMO PARTE DEL PLAN DE TRATAMIENTO PARA REDUCIR EL COLESTEROL HASTA ... Hispanic PR Wire (Comunicado de prensa)

Düşük kolestrol prostat kanserinden koruyabilir  -  ‎Nov 3, 2009‎
Doktorlar, kolesterol tedavisi için kullanılan Lipitor ve Crestor gibi statin tipi ilaçları erkeklere tavsiye etmek için henüz erken olduÄŸunu belirterek, ... CNN Türk

Ateronon, al via la sperimentazione di massa  -  ‎Nov 6, 2009‎
...come nel caso di Crestor, nuovo farmaco autorizzato dalla FDA statunitense per combattere il colesterolo alto nei bambini dai 10 ai 17 anni. ... AgoraVox Italia

AstraZeneca Ersteinschätzung  -  ‎Nov 13, 2009‎
Im US-Patentverfahren bezüglich Crestor gebe es Chancen für ein positives Ergebnis. Generischer Wettbewerb müsse aber berücksichtigt werden. ... FINANZEN.NET NEWS

Ð?еÑ?мотрÑ? на кризиÑ? прибыль AstraZeneca Ñ?оÑ?тавила до 2,1 млрд. долл.  -  ‎Nov 3, 2009‎
Ð’ чаÑ?тноÑ?ти увеличение продаж произошло за Ñ?чёт роÑ?та Ñ?проÑ?а на препараты Toprol-XL и Crestor, говоритÑ?Ñ? в Ñ?ообщении компании. ... ИИА. Ремедиум

스타틴 복용, ë?…ê°? ì?¸í•œ 사ë§?률 50% ê°?소해  -  ‎Oct 29, 2009‎
...ì?´ë²ˆ 시험ì—? í?¬í•¨ë?œ 스타틴ì?€ 아스트ë?¼ì?˜ 'í?¬ë ˆìŠ¤í† (Crestor)', BMSì?˜ '프ë?¼ë°”콜(Pravachol)'ê³¼ 머í?¬ì?˜ '메바코(Mevacor)'ì?´ë‹¤. ë?°ì?¼ë¦¬íŒœ ì?´ì˜?ì•„ 기ìž?. 데일리팜

阿斯利康第三季净盈利增长22%  -  ‎Oct 29, 2009‎
...季度è?¥æ”¶å¢žé•¿5.5%,从上年å?ŒæœŸçš„78亿美元增至82亿美元,主è¦?得益于胆固醇è?¯ç‰©Crestor的强劲需求ã€?甲æµ?疫苗的销售,以å?Šä»¿åˆ¶è?¯ç«žäº‰çš„å‡?少。 在固定汇率的基础上,è?¥æ”¶ ... 新浪网

Cholesterol Drug Crestor Poses Risks, Journal Says  -  May 24, 2005
By Marc Kaufman. The powerful cholesterol-lowering drug Crestor is significantly more likely than other statins to cause muscle deterioration that can lead ... Washington Post

AstraZeneca's Crestor cuts deaths, heart attacks  -  Nov 9, 2008
By Bill Berkrot and Ransdell Pierson. NEW ORLEANS, Nov 9 (Reuters) - AstraZeneca's (AZN.L) cholesterol fighter Crestor dramatically cut deaths, ... Reuters

Pfizer Unfazed By Positive Crestor Trial Data  -  Mar 14, 2006
Bear Stearns maintained sales estimates for Pfizer's blockbuster Lipitor following the release of positive trial results for rival cholesterol drug Crestor. ... Forbes

Crestor Warning A Boon For Astra--Or Pfizer?  -  Mar 3, 2005
NEW YORK - AstraZeneca strengthened the warnings on its cholesterol-lowering drug Crestor, which has been dogged by criticism regarding safety since its ... Forbes

Pfizer Irked by Crestor Data  -  Mar 13, 2006
By TSC Staff 03/13/06 - 05:29 PM EST. A two-year study shows that AstraZeneca's (AZN Quote) cholesterol fighter Crestor reversed plaque buildup in the ... TheStreet.com - TheStreet.com (subscription)

AstraZeneca's Crestor cuts risk of heart problems, trial shows  -  Apr 1, 2008
By Stephen Foley in New York. AstraZeneca, the drug company, said it was halting a 15000-patient study of its blockbuster cholesterol medicine Crestor, ... Independent

FDA rejects Crestor petition  -  Mar 14, 2005
By Julie Appleby, USA TODAY. The anti-cholesterol drug Crestor does not pose a greater risk of muscle damage than other drugs like it, the FDA said Monday, ... USA Today

Study: Crestor Not As Effective As Hoped  -  Mar 25, 2007
AstraZeneca PLC's Crestor cholesterol drug slowed thickening in the neck arteries of people at low risk for heart attacks and strokes, but it failed to ... FOXNews

Astrazeneca's Crestor gets FDA approval for atherosclerosis  -  Nov 9, 2007
By Sten Stovall. LONDON (MarketWatch) -- AstraZeneca PLC Friday said its cholesterol-lowering drug Crestor has been approved in the US for the treatment of ... MarketWatch

Shionogi shares soar on success of Crestor trial  -  Apr 1, 2008
TOKYO (Reuters) - Shares in Japanese drug maker Shionogi & Co Ltd (4507.T: Quote, Profile, Research) soared nearly 8 percent on Tuesday, boosted by news ... Reuters UK

AZ and Abbott to develop two-in-one pill from Crestor  -  Jul 6, 2006
By Sam Lister, Health Correspondent. CRESTOR, the blockbuster statin taken to lower cholesterol, is to be combined with another compound to make a ... Times Online

New Crestor Death Reported  -  Jan 12, 2005
By Daniel J. DeNoon. A patient taking the cholesterol-lowering drug Crestor (search) has died, the drug's manufacturer reported today. ... FOXNews

Crestor slows plaque growth in low-risk patients  -  Mar 26, 2007
By Bill Berkrot. NEW ORLEANS (Reuters) - AstraZeneca Plc's cholesterol drug Crestor significantly slowed build-up of plaque in the main artery supplying ... Reuters

Astra's Crestor fails in new heart-failure study  -  Aug 31, 2008
By Ben Hirschler. MUNICH, Aug 31 (Reuters) - AstraZeneca Plc's (AZN.L) cholesterol drug Crestor has failed in a second clinical trial for heart failure, ... Reuters

AstraZeneca's Crestor fails in heart-failure study  -  Nov 5, 2007
By Ben Hirschler and Ransdell Pierson. LONDON/NEW YORK (Reuters) - Heart-failure patients given AstraZeneca Plc's Crestor and standard drugs are just as ... Reuters UK

Vytorin is better than Crestor, says study - Jun. 19, 2006  -  Jun 19, 2006
By Aaron Smith, CNNMoney.com staff writer. NEW YORK (CNNMoney.com) - Merck and Schering-Plough announced a study on Sunday showing that their combination ... CNNMoney.com

FDA Warns AstraZeneca On Crestor Marketing  -  Mar 11, 2005
NEW YORK - For the second time in four months, the Food and Drug Administration's Division of Drug Marketing, Advertising, and Communications (DDMAC) has ... Forbes

Crestor cuts heart disease risks by 44%  -  Nov 11, 2008
The world's most popular anti-cholesterol drug Crestor could reduce by 44 per cent the risk of heart problems among patients who currently don't face a high ... Sydney Morning Herald

AstraZeneca Sues Generic Companies on Crestor Copies  -  Dec 12, 2007
By Angela Cullen. Dec. 12 (Bloomberg) -- AstraZeneca Plc, the UK's second- largest pharmaceutical company, sued seven generic-drug makers including Apotex ... Bloomberg

Crestor sales give AZ heart  -  Mar 29, 2006
By Richard Irving. ASTRAZENECA'S recovery under its new chief executive gathered strength yesterday when the company reported the biggest weekly jump in ... Times Online

AstraZeneca's Crestor in spotlight at heart meeting  -  Nov 6, 2008
By Bill Berkrot. NEW YORK (Reuters) - AstraZeneca's powerful cholesterol fighter Crestor will take center stage at the American Heart Association scientific ... Reuters

Astra's Crestor faces generic threat  -  Nov 1, 2007
By Ben Hirschler. LONDON (Reuters) - AstraZeneca (AZN.L) said on Thursday its blockbuster cholesterol medicine Crestor faced a generic challenge from ... Reuters UK

Crestor warnings too weak, group says  -  Mar 10, 2005
By Julie Appleby, USA TODAY. Warnings added to anti-cholesterol drug Crestor last week sharply understate the drug's risk, the consumer group Public Citizen ... USA Today

Abbott and AstraZeneca to co-market Crestor  -  Aug 14, 2008
NEW YORK --Drug maker Abbott Laboratories will co-promote the cholesterol drug Crestor in the US after Abbot expanded its relationship with AstraZeneca PLC, ... Boston Globe

Reuters Summit-Astra forecasts renewed Crestor growth  -  Nov 12, 2007
By Ben Hirschler. NEW YORK, Nov 12 (Reuters) - AstraZeneca Plc (AZN.L) expects its anti-cholesterol drug Crestor to pick up business again in the United ... Reuters

… Schering-Plough say FDA oks positive comparitor for VYTORIN vs...  -  Oct 5, 2006
...'VYTORIN now has been shown in clinical studies to provide greater LDL cholesterol lowering efficacy versus Lipitor, Crestor and Zocor at all study dose ... Forbes

AstraZeneca's Crestor, Linked to Muscle Risk, Posts Sales Gains  -  May 27, 2005
By Kerry Dooley Young and Michelle Fay Cortez. May 27 (Bloomberg) -- AstraZeneca Plc, Europe's third- largest drugmaker, regained as much as 50 percent of ... Bloomberg

AstraZeneca's Crestor sees market share stall-Citi  -  Jun 8, 2007
LONDON, June 8 (Reuters) - AstraZeneca Plc's (AZN.L) key cholesterol drug Crestor has seen its market share growth in the United States stall, ... Reuters

Crestor boost for AstraZeneca  -  Nov 11, 2008
By Alistair Dawber. The Anglo-Swedish drug group AstraZeneca got a boost yesterday when its anti-cholesterol treatment, Crestor, was shown to cut the ... Independent

Article: Cholesterol Drug Crestor Poses Risks, Journal Says; Study …  -  May 24, 2005
Cholesterol Drug Crestor Poses Risks, Journal Says; Study Suggests Use Only as Last Resort ... find The Washington Post articles. Pay-Per-View - Washington Post - HighBeam Research

AstraZeneca Profit Rises, Helped by Seroquel, Crestor  -  Jul 27, 2006
By Etain Lavelle. July 27 (Bloomberg) -- AstraZeneca Plc, the UK's second- largest drugmaker, said second-quarter profit rose as more patients took Seroquel ... Bloomberg

AstraZeneca trial to compare Crestor and Lipitor  -  Jan 15, 2008
LONDON, Jan 15 (Reuters) - AstraZeneca Plc (AZN.L) announced on Tuesday the first head-to-head clinical trial comparing its cholesterol-fighting drug ... Reuters

Article: FDA says Crestor must warn users of possible muscle damage. ...  -  Mar 3, 2005
FDA says Crestor must warn users of possible muscle damage. ... find Chicago Tribune (Chicago, IL) articles. Byline: Bruce Japsen Mar. Pay-Per-View - Chicago Tribune - HighBeam Research

AstraZeneca's Crestor 'to benefit most' from ENHANCE statin study - …  -  Apr 9, 2008
LONDON (Thomson Financial) - AstraZeneca Plc.'s blockbuster statin Crestor is set to benefit most from a study which showed that a key rival had little ... Forbes

Article: Still Taking Crestor? - The Washington Post | HighBeam...  -  May 31, 2005
Still Taking Crestor? ... find The Washington Post articles. A study last week found that the cholesterol-lowering drug Crestor (rosuvastatin) is two to six ... Pay-Per-View - Washington Post - HighBeam Research

Generic Zocor Expected to Challenge Lipitor  -  Jun 16, 2006
Experts said AstraZeneca PLC's Crestor and Vytorin, made by a joint ... Reports have linked Crestor to higher risk of a serious kidney and muscle problems. ... FOXNews

… Effects of AstraZeneca's CRESTOR(R) (Rosuvastatin Calcium) on...  -  Nov 7, 2007
Results demonstrated that CRESTOR significantly slowed the progression of CIMT in all ... The new analysis showed that CRESTOR, when compared with placebo, ... Free with registration - PR Newswire - AccessMyLibrary.com

Should Healthy People Take Statins?  -  Nov 14, 2008
Heart researchers from 26 countries tested the drug Crestor (generic name: ... The study released Sunday was sponsored by Crestor manufacturer AstraZeneca. ... NPR

Crestor should only be used as last resort - FDA chief  -  Feb 12, 2005
CRESTOR, AstraZeneca's most important new drug, should only be used after every other alternative has failed, David Graham, the outspoken government ... Independent

Research alert-Analyst sees negative Crestor data  -  Mar 16, 2007
NEW YORK, March 16 (Reuters) - Morgan Stanley said on Friday that AstraZeneca's (AZN.L) cholesterol fighter Crestor did not significantly reduce plaque in ... Reuters

AstraZeneca's Crestor winning US market share  -  Jun 5, 2008
LONDON, June 5 (Reuters) - AstraZeneca Plc's (AZN.L) cholesterol drug Crestor is gaining market share in the highly competitive US market, following recent ... Reuters

Article: Study: Crestor in high doses reverses heart disease - The...  -  Mar 14, 2006
Study: Crestor in high doses reverses heart disease ... find The Record (Bergen County, NJ) articles. MARILYNN MARCHIONE, THE ASSOCIATED PRESS The Record ... Pay-Per-View - The Record - HighBeam Research

Crestor May Not Cut Heart Failure Death  -  Nov 28, 2007
By Miranda Hitti. Nov. 28, 2007 -- Crestor, a statin drug that lowers LDL ("bad") cholesterol, may not reduce heart deaths in heart failure patients. ... WebMD

AstraZeneca Forecasts Run the Gamut  -  Apr 27, 2005
For example, expenses for the cholesterol drug Crestor will be much lower ... On the one hand, worldwide sales growth for Crestor looks good for the first ... TheStreet.com - TheStreet.com (subscription)

No home run for a heart disease drug, Crestor faces concerns on...  -  Mar 21, 2006
Plus, unlike other cholesterol-lowering drugs known as statins, there is no trial that proves AstraZeneca's Crestor leads to fewer heart attacks and strokes ... Pay-Per-View - Newsday - ProQuest Archiver

Astra's Crestor gets sales boost after positive data  -  Nov 24, 2008
By Ben Hirschler. LONDON, Nov 24 (Reuters) - US doctors are writing more prescriptions for AstraZeneca Plc's (AZN.L) cholesterol drug Crestor, ... Reuters

Broker says Astra's Crestor may face patent threat  -  Aug 31, 2007
LONDON, Aug 31 (Reuters) - Five generic firms have recently filed manufacturing applications with the US Food and Drug Administration to make a form of ... Reuters

Shionogi, AstraZeneca Start Nationwide Crestor Sales  -  Sep 25, 2006
By Hiroshi Suzuki. Sept. 25 (Bloomberg) -- Shionogi & Co. and AstraZeneca Plc, the UK's second-largest drugmaker, began nationwide sales of cholesterol ... Bloomberg

Still Taking Crestor?  -  May 31, 2005
Start Low One [Joel Rosenberg] strategy for reducing Crestor risk: Start with a low (five milligrams per day) dose, sometimes in combination with ezetimibe, ... Pay-Per-View - Washington Post - ProQuest Archiver

AstraZeneca posts 29% profit rise  -  Oct 30, 2008
LONDON (MarketWatch) -- AstraZeneca Thursday posted a sharp rise in quarterly net profit on improved sales for cholesterol drug Crestor and raised its ... MarketWatch

Abbott, Astra plan trial of combo cholesterol pill  -  Aug 31, 2007
The companies will pursue late-stage trials of the Crestor/ABT-335 combination, ... "Crestor was going to be paired with either Tricor or ABT-335, ... Reuters

Oils boost FTSE 100  -  Dec 4, 2006
0.3 percent in early trading on Monday, boosted by oil stocks and by Astrazeneca after a key competitive threat to its heart drug Crestor was removed. ... IBTimes

Crestor artery plaque regression reconfirmed-study  -  Mar 31, 2008
CHICAGO, March 31 (Reuters) - A new look at a two-year-old study of AstraZeneca Plc's (AZN.L) potent Crestor cholesterol fighter bolsters earlier findings ... Reuters

Summary: New Study Shows Crestor's Risks  -  May 23, 2005
A consumer group says it will resume efforts to remove Crestor from the market. HOW MUCH TO WORRY: The risk of side effects with any cholesterol drug, ... Los Angeles Times

AstraZeneca Ads Help Crestor Outpace Pfizer's Lipitor  -  Jan 30, 2007
By Etain Lavelle. Jan. 30 (Bloomberg) -- AstraZeneca Plc outspent larger rivals Pfizer Inc. and Merck & Co. by 30 percent on advertising for ... Bloomberg

Drug pipeline setbacks hit AstraZeneca and GSK shares  -  Oct 27, 2006
...sales 11 per cent higher at $6.52bn in the quarter, driven by a strong performance across its key products, such as cholesterol-beating drug Crestor. ... Scotsman

STOCKS NEWS EUROPE-Astra gains on dramatic Crestor data  -  Nov 10, 2008
Shares in AstraZeneca gain 4.1 percent, boosted by weekend news that its Crestor drug dramatically reduces the risk of deaths, heart attacks and strokes in ... Forbes

Astra drug Crestor finally gets German green light  -  Oct 30, 2008
LONDON, Oct 30 (Reuters) - It has been a long time coming but AstraZeneca's (AZN.L) blockbuster cholesterol drug Crestor has finally won approval in Germany ... Reuters

AstraZeneca's Crestor has room to grow  -  Nov 18, 2008
NEW YORK, Nov 18 - With only 10 percent of the US market share, AstraZeneca's <AZN.L> cholesterol fighter Crestor has plenty of room to grow, ... Alibaba News Channel

Generic Zocor won't be a market healer: As lapse of patent protection...  -  Dec 29, 2005
Meanwhile, Zocor's co-payments as a generic could be half of the co-payments of branded products like Lipitor and AstraZeneca PLC's Crestor. ... Free with registration - Chicago Tribune - AccessMyLibrary.com

… Collaboration to Develop and Commercialize CRESTOR(R) and Next- …  -  Jul 5, 2006
TriCor and CRESTOR are both lipid-regulating agents available within the ... It also is effective at reducing elevated LDL-C. CRESTOR is part of a class of ... RedOrbit

Crestor research program weighs on AstraZeneca shares  -  Apr 18, 2008
LONDON - AstraZeneca PLC is entering a final phase in an unprecedented research program to prove its Crestor cholesterol pill is better than Pfizer Inc.'s ... Boston Globe

AstraZeneca heart beats faster on Crestor hope  -  Nov 9, 2008
Shares in AstraZeneca rose in early trading after new research showed its Crestor drug treatment has reduced heart attacks and the risk of a stroke. ... Telegraph.co.uk

Advice about rosuvastatin (Crestor)  -  Nov 6, 2008
The Committee on Safety of Medicines has published this advice to doctors about prescribing rosuvastatin (Crestor).[1] ... guardian.co.uk

Heart Drug 'Hype'? Docs Debate Crestor  -  Dec 4, 2008
By NICOLE MARTIN, MD. On Nov. 9, when the results of a trial on the use of statin drugs became public at the American Heart Association meeting, ... ABC News

AstraZeneca Seeks a Stronger Pipeline  -  Feb 1, 2007
Crestor sales, at $625 million, nearly doubled. The company also announced a $4 billion share-buyback program. Like No.1 drugmaker Pfizer (PFE), ... BusinessWeek

Article: FDA Claim On Crestor Side Effects Is Disputed - The Washingto...  -  Mar 11, 2005
FDA Claim On Crestor Side Effects Is Disputed ... find The Washington Post articles. The rate of serious muscle damage in patients who took AstraZeneca ... Pay-Per-View - Washington Post - HighBeam Research

Health advisory likely for Abbott obesity drug.  -  Mar 13, 2005
FDA safety officer Dr. David Graham listed Crestor and Meridia among five potentially ... In its March 2 announcement regarding Crestor, the FDA said it was ... Free with registration - Chicago Tribune - AccessMyLibrary.com

Crestor may be riskier than rivals | Article from Deseret News (Salt...  -  May 24, 2005
Crestor may be riskier than rivals ... find Deseret News (Salt Lake City) articles. DALLAS -- Contrary to government claims, side effects happen more often ... Pay-Per-View - Deseret News - HighBeam Research

Drug trials under pressure  -  Jan 16, 2008
Consider another highly promoted drug, Crestor, a statin made by AstraZenica. Crestor was approved on the basis of trials in more than 10000 patients ... USA Today

HEALTH FOR LIFE The Power of Statins  -  Dec 6, 2008
Half of the volunteers took a daily 20mg tablet of Crestor; the rest took a placebo. ... Statins are expensive—a year's supply of Crestor or one of its ... Newsweek

Questions About the Crestor Study  -  Nov 10, 2008
..." A new study showed AstraZeneca is cholesterol drug Kress store sharply lower the risk of heart attacks. Among healthy patients I'm Kelsey Hubbard and ... FOXNews

New blow for Crestor  -  Mar 3, 2005
By Richard Irving. The regulator mitigated its warning by saying that the benefits of Crestor outweighed the risks when it was used as directed and that the ... Times Online

Crestor inhibits development of arteriosclerosis.  -  Apr 25, 2005
Results from the ORION study have shown an improvement in the atherosclerotic plaque status and therefore a reduced tendency towards atherosclerosis in ... Pay-Per-View - Dagens Industri - Factiva, from Dow Jones

Astrazeneca chief attacks 'unfounded' drug safety scares  -  Jan 28, 2005
The company's greatest product hope, cholesterol-lowering drug Crestor, has been hit by ... Sir Tom said fears over Crestor were, in the company's opinion, ... Telegraph.co.uk

JOURNAL: FDA ERRED ON RISK OF CRESTOR USE.(News) | Article …  -  May 24, 2005
JOURNAL: FDA ERRED ON RISK OF CRESTOR USE.(News) ... find The Cincinnati Post (Cincinnati, OH) articles. Byline: Marc Kaufman The Washington Post WASHINGTON ... Pay-Per-View - Cincinnati Post - HighBeam Research

Drug firm lowers sales forecasts  -  Jan 23, 2005
But the controversy over Crestor has continued because of the death of a patient from a severe muscle-wasting disease that is a rare side effect. ... Times Online

No Relief For AstraZeneca  -  Jan 31, 2005
The company could yet be dealt another setback with Crestor. Already, prescriptions for the drug have been falling as more information about the potentially ... BusinessWeek

AstraZeneca's first-quarter profit is up 31 pct.  -  Apr 29, 2005
Worldwide sales of Crestor more than doubled to $273 million in the first ... But now that the Food and Drug Administration has rejected a Crestor recall ... $2.95 - Philadelphia Inquirer - NewsBank

Heart Disease: Not About Cholesterol?  -  Apr 15, 2008
Its drug, Crestor, had been late to the cholesterol-lowering game, and it lagged behind ... But if the trial showed that Crestor worked in patients with low ... BusinessWeek

Deaths linked to heart drugs  -  Mar 6, 2005
Last week the FDA said patients taking Crestor or other statins might be at higher risk of kidney failure for reasons other than the drug. ... Times Online

Saudi Group Welcomes Approval of Dietary Supplement Crestor  -  Jan 9, 2008
RIYADH, 9 January 2008 — The Saudi Heart Association has welcomed the US Food and Drug Administration's (FDA) recent approval of Crestor (rosuvastatin) as a ... Arab News

Drugs 'can reverse heart disease'  -  Mar 14, 2006
They were given intensive treatment with rosuvastatin, known commercially as Crestor, which, along with other statins, was known to cut cholesterol levels. ... BBC News

Drugmakers cut back on television ad spending  -  Jul 4, 2005
...•Crestor. AstraZeneca spent $1.1 million on TV ads for anti-cholesterol drug Crestor in the first quarter, down from $9.4 million last year. ... USA Today

Study raises questions about Crestor's risks | Article from The...  -  May 24, 2005
Instead, the FDA ordered a warning on the label, saying Crestor could cause ... "We haven't found any convincing evidence that Crestor poses any more of a ... Pay-Per-View - The Record - HighBeam Research

AstraZeneca blames customer cut backs for disappointing results  -  Apr 25, 2008
The patents of Seroquel, the company's psychiatric treatment, and Crestor, an anti-cholesterol drug, face challenges in the next 18 months. ... Independent

Drug firms step up marketing efforts with coupons, free gifts aimed...  -  Jan 17, 2005
AstraZeneca Pharmaceuticals LLP is running a consumer-oriented promotional campaign that provides a 15-day, free supply of Crestor, its drug to treat high ... Free with registration - Boston Globe - AccessMyLibrary.com

Heart drug study merits caution; Crestor research a reminder of need...  -  Nov 11, 2008
Heart drug study merits caution; Crestor research a reminder of need for industry accountability.(NEWS)(Editorial) ... find Star Tribune (Minneapolis, ... Pay-Per-View - Star Tribune - HighBeam Research

Heart 'wonder drug' punted  -  Mar 19, 2006
..."We're excited about launching the drug known as Crestor in South Africa. Crestor blocks the production of cholesterol in the body." ... Independent Online

… $50,000 Donation Through The CRESTOR(R) Charity Challenge at PGA …  -  Feb 10, 2005
The CRESTOR(R) Charity Challenge is a season-long competition that recognizes and rewards ... For Choi and Trahan's performances, CRESTOR, an AstraZeneca ... Euro am Sonntag

AstraZeneca and Pfizer get statins all-clear from the Food and Drug …  -  Sep 30, 2008
Astra's Crestor and Pfizer's Lipitor are among the companies' most successful blockbuster treatments. The Food and Drug Administration did not find any ... Daily Mail

Bristol-Myers net income sinks while AstraZeneca earnings jump  -  Jan 27, 2005
Meanwhile, analysts worry about the future of AstraZeneca's cholesterol medicine Crestor following the disclosure last November that a prominent scientist ... San Diego Union - Tribune - San Diego Union Tribune

Crestor Sales Boost AstraZeneca  -  Jul 31, 2008
By ELENA BERTON. LONDON -- AstraZeneca PLC on Thursday reported a 13% rise in second-quarter net income, helped by strong sales of cholesterol drug Crestor ... Subscription - Wall Street Journal Online - Dow Jones & Company

… Receives $50,000 Donation Through The CRESTOR(R) Charity Challeng  -  Oct 24, 2005
The CRESTOR(R) Charity Challenge is a season-long competition that recognizes and rewards the ... CRESTOR is the presenting sponsor of TOUR Fantasy Golf at ... Free with registration - PR Newswire - AccessMyLibrary.com

Here is important safety information about CRESTOR you need to know.  -  Sep 20, 2005
CRESTOR is prescribed along with diet for lowering high cholesterol and has not been determined to prevent heart disease, heart attacks, or strokes. ... St. Petersburg Times - Google News Archive

Drug firm profits beat forecasts  -  Oct 27, 2005
Sales of its top five products - including cholesterol drug Crestor, ... The slow uptake of Crestor in the lucrative US market has also concerned investors. ... BBC News

Statins aren't magic pills, doctors say  -  Nov 23, 2008
Although many doctors hailed the study as a major breakthrough, a closer look at the research suggests that statins (like Crestor, from AstraZeneca, ... San Francisco Chronicle

AstraZeneca Q3 beats forecasts; raises full year guidance UPDATE  -  Oct 27, 2005
...percent; while Crestor sales rose 23 pct to 325 mln usd, and its market rhare rose to 6.8 pct. Symbicort sales in the third quarter rose 28 pct to 240 mln ... Forbes

A Heart-Stopping Deal  -  Dec 22, 2005
The company's cholesterol drug, Crestor, has been dogged by safety controversies--although Astra says they are unfounded. Moreover, AstraZeneca has had ... Forbes

Lipitor to Face Pressure From Insurers  -  Mar 19, 2007
AstraZeneca's Crestor and Vytorin, made by Merck and Schering-Plough Corp., have been gaining market share. Each can get cholesterol lower than Lipitor. ... FOXNews

Brand Names/Synonyms:
Crestor is also known by the following brand names and/or synonymsCrestor; Rosuvastatin; Rosuvastatin [Inn]; ZD 4522

Drug Category:
Crestor is categorized under the following by the FDA: Anticholesteremic Agents; HMG-CoA Reductase Inhibitors; ATC:C10AA07

Dosage Forms:
TABLET

Absorption:
20%

Interactions:
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Chemical IUPAC Name:
7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid





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