Crixivan

This page contains recent news articles, when available, and an overview of Crixivan but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Crixivan
(when available)

Pharmacology and use:
Indinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Indinavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. For the treatment of HIV infection

Mechanism Of Action:
Indinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

News Articles on Indinavir

Lower Norvir Boosting Dose Possible  -  ‎Oct 29, 2009‎
With lopinavir, Crixivan and Aptivus, there was evidence that the dose of Norvir had a direct effect on the blood levels of these drugs. ... AIDSmeds.com HIV/AIDS Treatment News

Dietary Supplements May Increase Longevity Of HIV Patients  -  ‎Nov 8, 2009‎
Specifically the use of St. John's Wort with Crixivan (indinavir sulfate) reduced the effectiveness of this medication. Other protease inhibitors are ... The AIDS Beacon (blog)

Merck Announces Third-Quarter 2009 Financial Results  -  ‎Oct 22, 2009‎
CANCIDAS, COSOPT, CRIXIVAN, EMEND, FOSAMAX, INVANZ, ISENTRESS, MAXALT, PRIMAXIN, PROPECIA, PROSCAR, STOCRIN, TIMOPTIC/TIMOPTIC XE, TREDAPTIVE, TRUSOPT, ... Reuters

Atazanavir et lithiases urinaires  -  ‎Nov 2, 2009‎
...pour l'autre, à l'indinavir (Crixivan®), inhibiteur de protéase. La spectrophotométrie a mis en évidence des cristaux d'atazanavir dans les calculs. ... vih.org

Merck Sharp and Dohme (MSD) Again Reduces Price of STOCRIN ( …  -  Mar 16, 2006
Today's announcement comes five years to the day, March 7, 2001, since MSD first announced that it was reducing the prices of STOCRIN and CRIXIVAN in ... AllAfrica.com

Argentinian generic indinavir compares well with Crixivan  -  Mar 28, 2005
Systemic exposure to indinavir is similar whether using Crixivan brand name indinavir or a generic indinavir formulation from Argentina, according to a ... Aidsmap

Pregnant women should not use Crixivan.(FDA Bits)(Food and drug …  -  Apr 1, 2005
Pregnant women should not use Crixivan.(FDA Bits)(Food and drug administration)(Brief Article) ... find HIV Treatment: ALERTS! articles. Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

Merck & Co cuts HIV AIDS drug prices 22%.(Merck and Company Inc …  -  Mar 20, 2006
At the time, the decision was taken by the drugmaker to offer Stocrin and Crixivan to the poorest developing countries at a break-even price. ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Dry skin affects up to half of adults with HIV  -  Oct 5, 2007
The study, published in the October issue of AIDS, also found that use of the protease inhibitor indinavir (Crixivan) increased the risk of having dry skin. ... Aidsmap

Pregnant women should not use Crixivan.(FDA Bits)(Food and drug …  -  Apr 1, 2005
The protease inhibitor Crixivan should not be used in HIV+ pregnant women. New data have shown that blood levels of Crixivan are lower in pregnant women, ... $4.95 - HIV Treatment: ALERTS! - ECNext

How to take Bortezomib from Consumer Reports Health.  -  Jan 8, 2007
...certain medications to treat human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) such as indinavir (Crixivan), ... consumerreports.org

Nilotinib Side Effects from Consumer Reports Health.  -  Jan 1, 2008
...indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); moxifloxacin (Avelox); nefazodone; ... consumerreports.org

NRTI-sparing combination of ritonavir-boosted indinavir and efavirenz...  -  Aug 10, 2006
...of ritonavir (Norvir)-boosted indinavir (Crixivan) and efavirenz (Sustiva). However, these improvements come at the cost of deteriorations in blood fat, ... Aidsmap

Study finds no link between brain-penetrating antiretroviral drugs...  -  Mar 22, 2006
Retrovir), d4T (stavudine, Zerit), 3TC (lamivudine, Epivir), abacavir (Ziagen), nevirapine (Viramune), efavirenz (Sustiva) and indinavir (Crixivan). ... Aidsmap

Adherence tips  -  Dec 8, 2005
Indinavir (Crixivan) capsules are especially sensitive to moisture, however, and should be stored away from other medications. ... NAPWA

Ã?ndice de lecciones  -  Mar 1, 2008
Crixivan es un medicamento anti-VIH que pertenece a la categoría de los inhibidores de ... Crixivan evita que las células T que están infectadas con el VIH, ... AIDSmeds.com HIV/AIDS Treatment News

Prix des inventeurs de l'année 2007  -  Apr 20, 2007
Le procédé Bosch, par exemple, a permis de réaliser un airbag salvateur, tandis que le Crixivan, inhibiteur de protéases, a révolutionné le traitement du ... Invention - Europe

Which Are The Easiest Drug Combinations? (A Look At Fewer Pills and …  -  Aug 17, 2007
Combine Crixivan with Norvir. Norvir boosts Crixivan levels in the bloodstream. This allows Crixivan to be taken fewer times a day, either with or without ... AIDSmeds.com HIV/AIDS Treatment News

Loislaw Federal District Court Opinions - RODRIGUEZ v. MANPOWER …  -  Sep 22, 2006
Plaintiff told her it was Crixivan. Crixivan is a drug used only for treating HIV. Pérez stated at her deposition that she did not know what Crixivan was ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Joseph Vacca (USA)  -  Nov 14, 2008
Crixivan nahm eine Sonderstellung ein, weil es ein anderes virales Ziel ins Visier nahm ... Bis heute haben Medikamente wie Crixivan das Leben all jener, ... European Patent Office

Article: Diarrhea dilemmas.(diarrhea and drug loperamide)(Brief...  -  Apr 1, 2005
New Pharmacokinetic Study Showed Blood Levels of Crixivan Boosted by ... Crixivan with ritonavir 100 mg. The blood levels in the Crixivan 1200 mg and ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

Article: Your Health.(Health & Fitness) - Daily Herald (Arlington...  -  Feb 19, 2007
New Pharmacokinetic Study Showed Blood Levels of Crixivan Boosted by ... Crixivan with ritonavir 100 mg. The blood levels in the Crixivan 1200 mg and ... Pay-Per-View - Daily Herald - HighBeam Research

Article: Merck CEO Resigns as Drug Probe Continues; House Panel …  -  May 6, 2005
Article: MERCK: FDA COMMITTEE RECOMMENDS CRIXIVAN(R), . ... Crixivan is the Merck registered trademark ... necessarily indicative of final FDA decisions to ... Pay-Per-View - Washington Post - HighBeam Research

protease | Definition of protease | HighBeam.com: Online Dictionary  -  Jul 12, 2006
CRIXIVAN is a type of HIV drug called a protease (PRO-tee-ase) inhibitor. How does CRIXIVAN work? CRIXIVAN is a protease inhibitor that fights HIV. ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

PIs Increase Heart Disease Risk, and NNRTIs Decrease It  -  Mar 21, 2008
After controlling for multiple factors, people taking the PIs Crixivan (indinavir) ... People using low-dose Norvir to boost Crixivan levels had fibrinogen ... AIDSmeds.com HIV/AIDS Treatment News

Merck Will Help Expand Access to HIV/AIDS Treatment In Least …  -  Feb 15, 2007
The prices of other formulations of STOCRIN and Merck's other HIV/AIDS medicine, CRIXIVAN (indinavir sulfate), remain unchanged. ... ChinaCSR.com

Tipranavir.(Pipeline HIGHLIGHTS) | Article from HIV Treatment:...  -  Apr 1, 2005
The protease inhibitor Crixivan should not be used in HIV+ pregnant women. New data have shown that blood levels of Crixivan are lower in pregnant women, ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

HIV Drugs Not at Fault for Causing Gain in Girth  -  Nov 1, 2005
Many also developed a paunch - nicknamed "Crix belly" after Crixivan, one protease inhibitor - and they gained weight in their upper trunks. ... New York Times

COLUMN ONE; The Ones HIV Left in Limbo; Salvage therapy is the last …  -  Jan 19, 2006
Fuzeon (two injections a day to help prevent the virus from fusing with normal cells); Crixivan (two pills a day; a protease inhibitor that interferes ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Article: Brazil Bypasses Patent on US AIDS Drug - AP Online |...  -  May 4, 2007
It would sell the AIDS drug Crixivan to developing countries for ... United States. It would also sell the AIDS drug Stocrin for $500 per patient per year . ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Bristol's shaky public image could get a lift from AIDS drug - Oct....  -  Oct 9, 2006
For example, Merck sells Stocrin and Crixivan at a reduced price to some 500000 patients in 76 developing nations. Regardless of sales, Atripla could ... CNNMoney.com

Article: Merck agrees to TV ad pre-clearance.(DTC REPORT) - Medical …  -  Jul 1, 2008
Article: MERCK: FDA COMMITTEE RECOMMENDS CRIXIVAN(R), . ... Crixivan is the Merck registered trademark ... necessarily indicative of final FDA decisions to ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Brazil AIDS Drug Negotiations Break Down | Article from AP Online | …  -  May 3, 2007
It would sell the AIDS drug Crixivan to developing countries for ... United States. It would also sell the AIDS drug Stocrin for $500 per patient per year . ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Article: Tx for noncompliant H. pylori patients.(CLINICAL CAPSULES)( …  -  Dec 1, 2005
...dosing with twice- daily dosing (1200 mg every 12 hours) of Crixivan. The first study compared Crixivan twice-daily versus Crixivan three-times daily . ... Pay-Per-View - Pediatric News - HighBeam Research

Brazil Bypasses Patent on US AIDS Drug | Article from AP Online | …  -  May 4, 2007
It would sell the AIDS drug Crixivan to developing countries for ... United States. It would also sell the AIDS drug Stocrin for $500 per patient per year . ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Brazil Minister Says No AIDS Drug Deal | Article from AP Online | …  -  Jul 14, 2005
It would sell the AIDS drug Crixivan to developing ... would also sell the AIDS drug Stocrin for $500 per ... with real prices. ... Pay-Per-View - AP Online - HighBeam Research

Los estigmas del virus  -  Jun 14, 2008
...“Cuando en 1996 empecé a tomar el cóctel de drogas (Crixivan + 3TC Complex), ... Yo al tipo no le había contado que tomaba Crixivan, ni siquiera que tenía ... Página 12

USPHS releases updated guidelines for management of occupational …  -  Dec 1, 2005
Indinavir (Crixivan) with Potential for serious or life- or without ritonavir threatening drug interactions; serious toxicity possible; consumption of eight ... $4.95 - American Family Physician - ECNext

Article: Ruling Puts Texas Vioxx Lawsuits on Hold - AP Online | …  -  Apr 21, 2007
Article: MERCK: FDA COMMITTEE RECOMMENDS CRIXIVAN(R), . ... Crixivan is the Merck registered trademark ... necessarily indicative of final FDA decisions to ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Article: Recommendation Against Vioxx Successor - AP Online | …  -  Apr 12, 2007
Article: MERCK: FDA COMMITTEE RECOMMENDS CRIXIVAN(R), . ... Crixivan is the Merck registered trademark ... necessarily indicative of final FDA decisions to ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Merck Lowers Price of HIV/AIDS Medication STOCRIN in Poor Countries  -  Mar 7, 2006
Today's announcement comes five years to the day, March 7, 2001, since Merck first announced that it was reducing the prices of STOCRIN and CRIXIVAN in ... Newsinferno.com

Article: FDA Panel Frowns on Vioxx Successor - AP Online | HighBeam …  -  Apr 13, 2007
Article: MERCK: FDA COMMITTEE RECOMMENDS CRIXIVAN(R), . ... Crixivan is the Merck registered trademark ... necessarily indicative of final FDA decisions to ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Article: Iman Promotes Auction for AIDS Funds - AP Online | HighBeam ...  -  Nov 30, 2006
It would sell the AIDS drug Crixivan to developing countries ... States. It would also sell the AIDS drug Stocrin for $500 per patient ... forever on the ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Indinavir use not recommended for pregnant HIV-infected patients, FDA...  -  Jan 13, 2005
The protease inhibitor indinavir (Crixivan) is not recommended for use in ... Crixivan is manufactured by Merck Sharpe & Dohme, and was approved for use in ... Aidsmap

Invirase (saquinavir, SQV)  -  Mar 1, 2008
Seis inhibidores de la proteasa: Crixivan (indinavir), Norvir (ritonavir), Kaletra (lopinavir/ritonavir), Reyataz (atazanavir); y Agenerase y Lexiva ... AIDSmeds.com HIV/AIDS Treatment News

Navy meds dwindle for woman with HIV  -  Jul 3, 2007
She takes out two white, oval Crixivan tablets and swallows them. In graduate school, Richelle knew she wanted to study HIV policy and said so in ... Marine Corps Times - Marine Corps Times (subscription)

The Saga Continues  -  Oct 21, 2005
Yes, it's true that Crix belly is caused by Crixivan just like beer bellies are caused by beer and pregnant bellies come from, well, pregnant bellies. ... Seattle Gay News

Kidney stones  -  Jan 31, 2008
...topiramate (Topamax), an anti-seizure drug; and indinavir (Crixivan), which is used to treat human immunodeficiency virus, the cause of AIDS. ... CNN International

Reyataz May Cause Kidney Stones  -  Jun 19, 2007
In clinical trials of Crixivan® (indinavir), one of the first PIs approved, kidney stones were documented in approximately 9% of patients taking the drug. ... AIDSmeds.com HIV/AIDS Treatment News

Aging HIV Patients Face Complicated Health Issues | Newsweek Health |...  -  Sep 18, 2008
Chew slowly began to wake from that nightmare with the approval of a new antiretroviral drug, Crixivan, that would help nurse him back to health. ... Newsweek

European Inventor of the Year Awards 2007: Biodegradable plastics, …  -  Apr 18, 2007
The Bosch Process, for instance, paved the way for the life-saving airbag, while Crixivan, a protease inhibitor, has revolutionised HIV treatment. ... European Patent Office

Calidad de vida - eluniversal.com  -  Dec 26, 2005
Me dijeron en Las Adjuntas que no tienen Crixivan, ¿saben ustedes para cuándo ... Nos informaron que no habrá Indinavir (Crixivan es el nombre de la marca ... El Universal - El Universal (Venezuela)

US Makes Strides in Fight Against AIDS | Article from AP Online | …  -  Jun 4, 2006
It would sell the AIDS drug Crixivan to developing countries ... States. It would also sell the AIDS drug Stocrin for $500 per patient ... forever on the ... Pay-Per-View - AP Online - HighBeam Research

Merck & Co cuts AIDS drug prices to LDCs.(Brief article)  -  Feb 26, 2007
The prices of other formulations of Stocrin and Merck's other HIV/AIDS drug, Crixivan (indinavir sulfate), remain unchanged. ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Brazilian patent threat poses challenge to big pharma  -  Jun 23, 2005
Finally, Merck agreed to slash the prices of Crixivan by 65% to 47 cents from $1.33 for a 400 mg dose, and of Stocrin by 59% to 84 cents from $2.06 for a ... Pay-Per-View - Datamonitor News and Comment - Factiva, from Dow Jones

Ex-College Hoopster Helping Africans | Article from AP Online | …  -  Jun 17, 2005
It would sell the AIDS drug Crixivan to developing countries ... States. It would also sell the AIDS drug Stocrin for $500 per patient ... forever on the ... Pay-Per-View - AP Online - HighBeam Research

Solutions for an upset stomach.(HIV AND TRAVEL)(Brief Article)  -  Nov 8, 2005
Alka-Seltzer, Maalox, Tums, and Rolaids can interfere with the stomach's absorption of Agenerase, Crixivan, Rescriptor, and Reyataz, while Axid, Pepcid, ... $4.95 - The Advocate - ECNext

UN Campaigns to End AIDS in Kids | Article from AP Online | HighBeam ...  -  Oct 25, 2005
It would sell the AIDS drug Crixivan to developing countries ... States. It would also sell the AIDS drug Stocrin for $500 per patient ... forever on the ... Pay-Per-View - AP Online - HighBeam Research

Solutions for an upset stomach.(HIV AND TRAVEL)(Brief Article) |...  -  Nov 8, 2005
Alka-Seltzer, Maalox, Tums, and Rolaids can interfere with the stomach's absorption of Agenerase, Crixivan, Rescriptor, and Reyataz, while Axid, Pepcid, ... Pay-Per-View - The Advocate - HighBeam Research

Reyataz Oral : Uses, Side Effects, Interactions, Pictures, Warnings &...  -  Sep 30, 2008
Crixivan (indinavir sulfate) US prescribing information. Merck & Co., Inc. December, 2008. 7.Norvir (ritonavir) US prescribing information. ... WebMD

Merck buys rights to Canadian firm's HIV drug in early testing.  -  Oct 12, 2006
Merck already makes Crixivan and Stocrin, and says it is testing two other products, including an HIV vaccine. The transaction calls for Merck to pay ... Free with registration - Philadelphia Inquirer - AccessMyLibrary.com

The search for an HIV/AIDS vaccine  -  Nov 30, 2006
Quick to follow were protease inhibitors, like Crixivan, Viracept and Kaletra, drugs which did nothing to prevent the virus from replicating but kept it ... Gay and Lesbian Times

Ritonavir Oral : Uses, Side Effects, Interactions, Pictures, Warnings...  -  Sep 30, 2008
Crixivan (indinavir sulfate) US prescribing information. Merck & Co., Inc. January, 2004. 7.Viracept (nelfinavir mesylate) US prescribing information. ... WebMD

Ritonavir Oral : Uses, Side Effects, Interactions, Pictures, Warnings...  -  Sep 30, 2008
Crixivan (indinavir sulfate) US prescribing information. Merck & Co., Inc. December, 2008. 2.Viracept (nelfinavir mesylate) US prescribing information. ... WebMD

Grapefruit Juice Bad Mix With Some Rx Drugs  -  Jan 20, 2005
...tamoxifen, vinblastine, vincristine, Dextromethorphan (found in many over-the-counter cold medicines), Agenerase, Crixivan, Viracept, Norvir, Fortovase, ... FOXNews

Note d'information aux patients sur les données de COPHAR I  -  May 3, 2005
...associations comportant une antiprotéase de type indinavir (Crixivan®) ou nelfinavir (Viracept®), et ayant un bon résultat virologique sous traitement, ... survivreausida.net

Les inventeurs de l'année récompensés pour leur apport à l' …  -  Apr 18, 2007
Le "procédé Bosch" a permis l'avènement de l'Airbag, qui a sauvé de nombreuses vies, tandis que l'inhibiteur de protéases Crixivan a révolutionné le ... European Patent Office

Blog this on:  -  Sep 20, 2007
The US firm created some of the first ARVs capable of treating HIV and AIDS (Crixivan and Stocrin), but has in the past been criticized for its methods of ... TIME

Biotech Behemoth - Forbes.com  -  Jan 10, 2005
Merck, for talent, grabbing chemist Paul Reider, who designed the complex production process for the breakthrough AIDS drug Crixivan. ... Forbes

[U] Walker v. Barnhart, 172 Fed.Appx. 423 (3d Cir. 03/06/2006)  -  Mar 6, 2006
He obtained and continued taking Zerit, Zithromax, Combivent, Acyclovir, Epivir, Guaifenex, Crixivan, Norvir, Sulfamethoxazole, Diflucan, and Viramune. ... $2.95 - U.S. Court of Appeals, Third Circuit - VersusLaw

Merck's Isentress HIV Medicine Approved by US FDA  -  Oct 12, 2007
...which markets it under the name Sustiva. Merck continues to market Stocrin outside the US and sells another older AIDS drug, Crixivan. Bloomberg

Leading HIV vaccine researcher joins Wyeth.  -  Nov 3, 2005
During his two decades at Merck, Emini helped lead five AIDS vaccine candidates into human research and worked on development of the HIV medicine Crixivan. ... Free with registration - Philadelphia Inquirer - AccessMyLibrary.com

Schor v. Abbott Laboratories, 457 F.3d 608 (7th Cir. 07/26/2006)  -  Jul 26, 2006
...amprenavir (AGENERASE®), atazanavir (REYATAZ®), fosamprenavir (LEXIVA®), indinavir (CRIXIVAN®), and nelfinavir (VIRACEPT®) are widely used. ... $2.95 - U.S. Court of Appeals, Seventh Circuit - VersusLaw

ALS remains unrelenting, and there's no cure in sight  -  Aug 20, 2006
...the HIV/ AIDS drug indinavir (Crixivan), the COX-2 inhibitor celecoxib (Celebrex), and a nerve-nourishing drug called insulin-like growth factor (IGF-1) ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Costs Grow for Common Medicare Drugs; Price Increase in Prescription ...  -  May 13, 2007
The Washington Post; March 15, 2001 ; 700+ words ... ... protease inhibitor, Crixivan. Together, this is far more than the $350 a year price offered by some ... Pay-Per-View - Washington Post - HighBeam Research

Prudential Insurance Co. of America v. Life Partners, Inc., No. 07...  -  May 8, 2008
He previously had been treated with Kaletra, Viread, AZT, DDI, Viramune, Norvir, Viracept, Ziagen, Sustiva, Trizivir, Fortovase and Crixivan. ... $2.95 - U.S. District Court, District of... - VersusLaw

Merck & Co Inc. issued the following statement in a press release, on...  -  May 5, 2007
In fact, Merck's global HIV pricing policy offers Brazil access to both STOCRIN and CRIXIVAN at the lowest price of any country with a comparable wealth and ... ag-IP-news Agency

Kidney Stones - What Increases Your Risk  -  May 30, 2007
...have more problems with kidney stones. Medicine. Some medicines, such as acetazolamide (Diamox), or indinavir (Crixivan), can cause kidney stones to form. WebMD

Ritonavir Oral : Uses, Side Effects, Interactions, Pictures, Warnings...  -  Oct 24, 2006
Crixivan (indinavir sulfate) US prescribing information. Merck & Co., Inc. December, 2008. 5.Kaletra (lopinavir/ritonavir tablets) US prescribing ... WebMD

REGIONAL NEWS: MEDIQUEST SAYS FDA WILL ISSUE EARLY …  -  Jun 26, 2008
The new drug, indinavir, made by Merck & Co., appears in early trials to be ... Crixivan, came 42 days after the company submitted its application to the ... Pay-Per-View - Seattle Post-Intelligencer - HighBeam Research

Merck Sharp&Dhome lamenta la decisión de Brasil de suspender la …  -  May 5, 2007
Y mantiene que comercializa el 'Stocrin' y el 'Crixivan' a un precio menor que en "cualquier país con una riqueza y carga de enfermedad comparable". ... IBLNEWS

Merck buys rights to Canadian firm's HIV drug in early testing. |...  -  Oct 12, 2006
Merck already makes Crixivan and Stocrin, and says it is testing two other products, including an HIV vaccine. The transaction calls for Merck to pay ... Pay-Per-View - Philadelphia Inquirer - HighBeam Research

Article: Ending of HIV vaccine trial jolts industry. - Philadelphia...  -  Oct 10, 2007
Merck already makes Crixivan and Stocrin ... testing two other products, including an HIV vaccine. The transaction calls for Merck to pay Ambrilia $17 ... Pay-Per-View - Philadelphia Inquirer - HighBeam Research

Article: Woman blitzes to win `Wheel' bonus round.(NEWS) - Star...  -  Jan 7, 2005
This is life in the bonus round, after all, and Schalchlin says he ... that developed Crixivan. Life in the bonus round, it turns out, ... Pay-Per-View - Star Tribune - HighBeam Research

Philadelphia Inquirer, The : Merck ex-chief on caustic e-mail - <br>By...  -  Oct 13, 2005
He then recounted an unrelated FDA hearing on Merck's HIV drug, Crixivan, in which a reviewer complimented Merck for its presentation that made critics look ... $2.95 - Philadelphia Inquirer - NewsBank

Vioxx tarnished Merck's sterling image, hurting morale at the vast...  -  Apr 3, 2005
Its huge manufacturing facility made only a few thousand doses of liquid-form Vioxx, but it pumps out vast quantities of other drugs, including Crixivan for ... $2.95 - Philadelphia Inquirer - NewsBank

Business News in Brief  -  Oct 13, 2006
Merck already makes Crixivan and Stocrin, and it says it is testing two other products, including an HIV vaccine. The transaction calls for Merck to pay ... $2.95 - Philadelphia Inquirer - NewsBank

Brasil aguanta el pulso contra el sida  -  Jun 5, 2007
Y mantiene que comercializa el Stocrin y el Crixivan a un precio menor que en "cualquier país con una riqueza y carga de enfermedad comparable". ... El País - El País (España)

AIDS: Die Pille danach  -  Jul 13, 2006
Crixivan und Viracept sind hochwirksame Proteasehemmer. Diese modernen Medikamente gaben erstmals Hoffnung, daß Aids eines Tages heilbar sein wird. ... FOCUS Online

DRUGS FAILING FOR 40,000 AMERICANS WITH AIDS  -  Feb 5, 2006
Fuzeon (two injections a day to help prevent the virus from fusing with normal cells); Crixivan (two pills a day; a protease inhibitor that interferes ... $2.95 - Miami Herald - NewsBank

Vaccination and Enrollment Are Discontinued in Phase II Trials of...  -  Sep 21, 2007
In the 1990s, Merck scientists discovered the protease inhibitor, CRIXIVAN([R]) (indinavir sulfate), and the non-nucleoside reverse transcriptase inhibitor, ... Free with registration - Business Wire - AccessMyLibrary.com

Rivera v. Barnhart, No. 03 Civ. 10127 (SDNY 02/01/2006)  -  Feb 1, 2006
According to the records, Rivera did not begin treatment for his condition until November 2001, when he began taking Combivir, Crixivan and Norvir, ... $2.95 - U.S. District Court, Southern District... - VersusLaw

Loislaw Federal District Court Opinions - SCHOR v. ABBOTT …  -  Jul 12, 2005
At least seven other boosted PIs, not manufactured by defendant, are boosted by Norvir: Agenerase, Crixivan, Fortovase, Invirase, Lexiva, Reyataz, ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Plea deal sends brother's killer to prison for manslaughter.(Local) |...  -  May 25, 2005
A state fund to help AIDS patients has a waiting list for people who want to start therapy with Crixivan, said Joseph Riddick of the Eastern Regional AIDS ... Pay-Per-View - Virginian-Pilot - HighBeam Research

Merck price attack on Teva worries generics biz | Article from...  -  Jun 23, 2006
Teva and the FDA also warned about ... the generic erythromycin and Merck & Co.'s AIDS pill Crixivan, as a precaution. Teva this month sent a letter to ... ... Pay-Per-View - Jerusalem Post - HighBeam Research

AIDS activists fault USefforts | Article from The Record (Bergen...  -  Jun 1, 2006
B, Two Star P, One Star B AIDS activists welcomed Merck & Co ... percent to 55 percent. In the United States, Crixivan costs $6016 per ... ... Pay-Per-View - The Record - HighBeam Research

St. Paul Pioneer Press : LIVER TESTS MANDATED TO AVOID SUDDEN …  -  Apr 13, 2005
...griseofulvin (Gris-PEG), imatinib (Gleevec), indinavir (Crixivan), isoniazid, isotretinoin (Accutane), itraconazole (Sporanox), ketoconazole (Nizoral), ... $2.95 - St. Paul Pioneer Press - NewsBank

Rivera v. Barnhart, No. 03 Civ. 10127 (SDNY 03/08/2006)  -  Mar 8, 2006
According to the records, Rivera did not begin treatment for his condition until November 2001, when he began taking Combivir, Crixivan and Norvir, ... $2.95 - U.S. District Court, Southern District... - VersusLaw

THE ESSENTIALS  -  Jul 25, 2007
HIV drugs: saquinavir (Fortovase, Invirase), indinavir (Crixivan). Immunosuppressant drugs: cyclosporine (Neoral, Sandimmune), tacrolimus (Prograf) ... Pay-Per-View - Providence Journal - ProQuest Archiver

AIDS drug works as first treatment in study | Article from Deseret...  -  Aug 13, 2006
The two others are reverse transcriptase, which is targeted by drugs including Viread, and protease, attacked by Merck's Crixivan and other medicines. ... Pay-Per-View - Deseret News - HighBeam Research

Virginian-Pilot, The : gRAPEFRUIT, ITS JUICE CAN INTERFERE WITH …  -  Jul 30, 2007
HIV drugs: saquinavir (Fortovase, Invirase), indinavir (Crixivan). * Immunosuppressant drugs: cyclosporine (Neoral, Sandimmune), tacrolimus (Prograf) ... $2.95 - Virginian-Pilot - NewsBank

Saving face; Province urged to pay for procedure  -  Jul 22, 2005
...where unsightly lumps of fat accumulate under the skin of the back (a buffalo hump) and belly (called Crixi belly, after the drug Crixivan). ... Pay-Per-View - Toronto Star - ProQuest Archiver

Article: Tough pill: Prescription instructions causing confusion -...  -  Nov 30, 2006
Merck will continue to study twice-daily dosing of Crixivan in combination trials ... Journal of Dairy Science. Article: A Systems Comparison of Once- ... Pay-Per-View - Chicago Sun-Times - HighBeam Research

An AZ guide for essential terms relating to HIV/Aids  -  Oct 22, 2008
Indinavir (Crixivan): a protease inhibitor from Merck. Indinavir must be taken every eight hours on an empty or mostly empty stomach; fat interferes with ... The Times

Brand Names/Synonyms:
Crixivan is also known by the following brand names and/or synonymsCompound J; Crixivan; Indinavir; Indinavir Sulfate; Indinavir [Usan]

Drug Category:
Crixivan is categorized under the following by the FDA: Anti-HIV Agents; ATC:J05AE02

Dosage Forms:
Oral capsules

Absorption:
Rapidly absorbed

Interactions:
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Chemical IUPAC Name:
1-[2-hydroxy-4-[(2-hydroxy-2,3-dihydro-1H-inden-1-yl)carbamoyl]-5-phenyl-pentyl]-4-(pyridin-3-ylmethyl)-N-tert-butyl-piperazine-2-carboxamide





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