Cutivate

This page contains recent news articles, when available, and an overview of Cutivate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Cutivate
(when available)

Pharmacology and use:
Fluticasone Propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma. For the maintenance treatment of asthma as prophylactic therapy and for patients requiring oral corticosteroid therapy for asthma

Mechanism Of Action:
Binds to the glucocorticoid receptor. Unbound corticosteroids cross the membranes of cells such as mast cells and eosinophils, binding with high affinity to glucocorticoid receptors (GR). The results include alteration of transcription and protein synthesis, a decreased release of leukocytic acid hydrolases, reduction in fibroblast proliferation, prevention of macrophage accumulation at inflamed sites, reduction of collagen deposition, interference with leukocyte adhesion to the capillary wall, reduction of capillary membrane permeability and subsequent edema, reduction of complement components, inhibition of histamine and kinin release, and interference with the formation of scar tissue. In the management of asthma, the glucocorticoid receptor complexes down-regulates proinflammatory mediators such as interleukin-(IL)-1, 3, and 5, and up-regulates anti-inflammatory mediators such as IkappaB [inhibitory molecule for nuclear factor kappaB1], IL-10, and IL-12. The antiinflammatory actions of corticosteroids are also thought to involve release of cytosolic phospholipase A2 which controls the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.

News Articles on Fluticasone Propionate

Housewife's eczema  -  ‎Dec 14, 2009‎
Usually we start with Dermovate and get the eczema to settle then we would go to Betnovate, a weaker steroid, then Cutivate. The patient is advised to keep ... Jamaica Observer

PharmaDerm Launches CUTIVATE(R) Lotion.  -  Oct 17, 2005
ATLANTA, Oct. 17 /PRNewswire/ -- PharmaDerm today announced the official launch of CUTIVATE (fluticasone propionate) Lotion, 0.05%, the only mid- potency ... $4.95 - PR Newswire - ECNext

Nycomed files lawsuit against Glenmark Generics  -  Dec 17, 2008
12 against Glenmark for its fluticasone propionate skin lotion, which is the generic version of Nycomed's Cutivate. If Glenmark wins the patent challenge, ... Reuters UK

Cutivate.(Drug overview)  -  Jan 22, 2007
Cutivate cream and ointment are prescribed for relief of inflamed, itchy rashes and other inflammatory skin conditions. When you use Cutivate, ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Aroma Spices to cutivate herbal plants.(organic spices)(Brief Article)  -  Jul 1, 2005
With the health food sector requiring a greater organic content and the tremendous potential of the north-eastern states of India to produce organic spices, ... $4.95 - Nutraceuticals International - ECNext

Ceragenix Announces Results from Phase IV Study of EpiCeram(TM) …  -  Apr 24, 2007
Both EpiCeram(TM) and Cutivate(R) produced significant improvement in patients' conditions after 28 days of treatment; There were no statistically ... Genetic Engineering News - Genetic Engineering News (press release)

Article: Steroid lotion approved for kids.(Products) - Family...  -  Jan 1, 2006
Cutivate (fluticasone propionate) lotion, 0.05%, a midpotency steroid lotion, is approved for the relief of t... Pay-Per-View - Family Practice News - HighBeam Research

Press Release: ALTANA Inc Acquires US Dermatology Business from …  -  Sep 30, 2005
In March 2005, GlaxoSmithKline received FDA approval for Cutivate(R) Lotion. Yet to mark its official launch, Cutivate Lotion will add a valuable exclusive ... Pay-Per-View - PR Newswire - HighBeam Research

Results from study of EpiCeram[TM] show comparable efficacy to mid- …  -  Aug 1, 2007
Both EpiCeram and Cutivate produced significant relief from itching and improvement in sleep habits after 28 days of treatment and that there was no ... $4.95 - Dermatology Nursing - ECNext

ALTANA Inc Acquires US Dermatology Business from GlaxoSmithKline …  -  Sep 30, 2005
In March 2005, GlaxoSmithKline received FDA approval for Cutivate(R) Lotion. Yet to mark its official launch, Cutivate Lotion will add a valuable exclusive ... $4.95 - PR Newswire - ECNext

Mergers & Acquisitions; US dermatology business acquired from …  -  Oct 28, 2005
Yet to mark its official launch, Cutivate Lotion will add a valuable ... "We will move forward with plans to launch Cutivate Lotion this fall and are ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Mergers & Acquisitions; US dermatology business acquired from …  -  Oct 25, 2005
Yet to mark its official launch, Cutivate Lotion will add a valuable ... "We will move forward with plans to launch Cutivate Lotion this fall and are ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Ceragenix Commences Second in Series of Clinical Trials.  -  Apr 25, 2007
The study demonstrated that both EpiCeram[TM] and Cutivate[TM] significantly reduced the symptoms of eczema and that there was no statistically significant ... Free with registration - Business Wire - AccessMyLibrary.com

Mergers & Acquisitions; US dermatology business acquired from …  -  Oct 24, 2005
Yet to mark its official launch, Cutivate Lotion will add a valuable ... "We will move forward with plans to launch Cutivate Lotion this fall and are ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Ceragenix Provides Update on Clinical Study.(Clinical report)  -  Jan 17, 2007
Over a four-week period, half of the subjects will receive treatment with EpiCeram, with the other half to receive treatment with Cutivate. ... Free with registration - Business Wire - AccessMyLibrary.com

Mergers & Acquisitions; US dermatology business acquired from …  -  Oct 24, 2005
Yet to mark its official launch, Cutivate Lotion will add a valuable ... "We will move forward with plans to launch Cutivate Lotion this fall and are ... Pay-Per-View - Biotech Business Week - Factiva, from Dow Jones

Press Release: PharmaDerm to Expand Product Offerings with Purchase …  -  Apr 29, 2008
Article: PharmaDerm Launches CUTIVATE(R) Lotion. ... CUTIVATE Lotion comes on the heels of PharmaDerm's recent acquisition of the prescription ... ... Pay-Per-View - PR Newswire - HighBeam Research

Article: Corticosteroid approved for psoriasis.(Products) - Family...  -  Jan 1, 2006
Article: Cutivate(R) Cream Receives FDA Clearance for Treatment of Atopic ... ... Cutivate is the Only Topical Corticosteroid Approved for Treatment in ... Pay-Per-View - Family Practice News - HighBeam Research

Ceragenix Obtains IRB Approval for Eczema Clinical Study; Study to …  -  Jun 27, 2006
Both EpiCeram and Cutivate will be applied twice daily to the affected skin areas. The study will also measure trans-epidermal water loss (TEWL), ... Genetic Engineering News - Genetic Engineering News (press release)

PharmaDerm acquires GSK's Rx derma business.  -  Oct 10, 2005
In March, GSK received US Food and Drug Administration approval for Cutivate. The drug's official launch has yet to be marked but Altana said in a press ... $4.95 - Pharma Marketletter - ECNext

Boy's eczema may require combination therapy - KID CARE  -  Jan 4, 2005
He was treated with Cutivate ointment, but it has come back again. ... Your son was treated with Cutivate, a mild topical steroid, which helped. ... Pay-Per-View - Star-Ledger - Factiva, from Dow Jones

Market Live from BSE - NSE, Latest Market Commentary | Economic …  -  Dec 17, 2008
Nycomed currently markets its fluticasone product as cutivate. Glenmark filed its ANDA containing a paragraph IV certification for a generic version of ... Economic Times

[U] Giordano v. Astrue, No. 07-1348 (DNJ 03/11/2008)  -  Mar 11, 2008
She was treated with Levaquin and cutivate ointment (R. 284, 297-98). Roger Brodkin of the Center for Dermatology in West Orange examined plaintiff two ... $2.95 - U.S. District Court, District of New... - VersusLaw

ASK DR. ERIKA ; Don't sweat search for causes of perspiration  -  Dec 24, 2006
She had it on her scalp and stomach and that has now cleared up with Cutivate. Unfortunately she now has it on her vagina and buttocks and the treatment is ... Pay-Per-View - Boston Herald - ProQuest Archiver

Ceragenix Pharmaceuticals Initiates EpiCeram(R) Clinical Trial; …  -  Aug 14, 2006
...multicenter pediatric clinical study designed to assess the efficacy of EpiCeram(R) compared to Cutivate(R), a commonly prescribed mid-strength steroid, ... Free with registration - Business Wire - AccessMyLibrary.com

Ceragenix Completes Patient Visits for EpiCeram(TM) Clinical Study  -  Feb 21, 2007
Over a four-week period, half of the subjects used EpiCeram while the other half used Cutivate(R), a mid-strength topical steroid. ... Genetic Engineering News - Genetic Engineering News (press release)

Allergic Contact Dermatitis  -  Feb 14, 2006
Nursing Measures: This patient's dermatitis persisted after topical treatment with a mid-potency corticosteroid (fluticasone propionate [Cutivate] 0.05%) ... RedOrbit

Company Profile Report  -  Mar 29, 2008
Altana Pharma Fluticasone Propionate; Altana Pharma Cutivate (Fluticasone Propionate); Altana Pharma Aclovate (Alclometasone Dipropionate) ... $50.00 - Revere Reports - Revere

Morning Updates for Friday, August 25,2006 - Featuring Sensor System ...  -  Aug 25, 2006
...efficacy of EpiCeram compared to Cutivate , a commonly prescribed mid-strength steroid, in patients with moderate-to-severe atopic dermatitis (eczema). ... Free with registration - M2 Presswire - AccessMyLibrary.com

Treatment options for atopic dermatitis.  -  Feb 15, 2007
There is no evidence that more frequent application of hydrocortisone butyrate 0.1% (Locoid) or fluticasone propionate 0.05% (Cutivate) cream is more ... Free with registration - American Family Physician - AccessMyLibrary.com

Article: More on the effectiveness of EpiCeram for atopic dermatitis.(...  -  Sep 1, 2008
This physiologic skin barrier repair cream proved itself the equal of fluticasone proprionate cream (Cutivate) in a 113-patient multicenter randomized ... Pay-Per-View - Skin & Allergy News - HighBeam Research

With topical steroids for AD, follow age-specific indications.(Clinica...  -  Aug 1, 2007
...indication for pediatric AD that don't carry a warning regarding HPA suppression are prednicarbate 0.1% cream and fluticasone 0.05% lotion (Cutivate). ... Free with registration - Pediatric News - AccessMyLibrary.com

Treating comorbidities may not benefit asthma.(Pulmonary Medicine) | ...  -  Apr 1, 2008
Cutivate (fluticasone propionate) cream 0.05%, a topical corticosteroid that was previously approved for use in adults only, has been approved to treat ... Pay-Per-View - Family Practice News - HighBeam Research

Article: EpiCeram cream alone clears atopic dermatitis.(Skin Disorders...  -  Sep 1, 2008
This physiologic skin barrier repair cream proved itself the equal of fluticasone proprionate cream (Cutivate) in a 113-patient multicenter randomized ... Pay-Per-View - Family Practice News - HighBeam Research

Allergic contact dermatitis.(Clinical Snapshot)  -  Feb 1, 2006
Nursing Measures: This patient's dermatitis persisted after topical treatment with a mid-potency corticosteroid (fluticasone propionate [Cutivate[R]] 0.05%) ... $4.95 - Dermatology Nursing - ECNext

Taro Reports Record Sales for Second Quarter and First Half.  -  Jul 28, 2005
This prescription pharmaceutical product is bioequivalent to GlaxoSmithKline's Cutivate(R) Ointment. Currently, Taro has 28 filings at the FDA. ... $4.95 - Business Wire - ECNext

Analyzing AD and allergies: longitudinal study of asthma development ...  -  Jul 1, 2007
In both arms, children could be treated with fluticasone propionate 0.05 percent cream (Cutivate, GlaxoSmithKline) as a rescue medication if needed after ... $4.95 - Dermatology Times - ECNext

Nycomed moves to next level on own terms.  -  Apr 28, 2008
An example is Cutivate. After acquiring the line from GSK, PharmaDerm extended it by offering the corticosteroid as a lotion in addition to a cream and an ... $9.94 - Chain Drug Review - Alacra Store

Morning Updates for Tuesday, September 5, 2006 - Featuring: Tally-Ho ...  -  Sep 5, 2006
...study designed to assess the efficacy of EpiCeram. compared to Cutivate., a commonly prescribed mid-strength steroid, in patients with moderate. $4.95 - M2 Presswire - ECNext

Be age-specific with topical steroids for AD.(Dermatologic Therapy)  -  Jun 1, 2007
...indication for pediatric AD that don't carry a warning regarding HPA suppression are prednicarbate 0.1% cream and fluticasone 0.05% lotion (Cutivate). ... $4.95 - Skin & Allergy News - ECNext

Alerts for Thursday, September 7, 2006 - Featuring Command Security, ...  -  Sep 7, 2006
Inc., has begun enrolling patients in a multicenter pediatric clinical study designed to assess the efficacy of EpiCeram(R) compared to Cutivate(R), ... $4.95 - M2 Presswire - ECNext

How to take Testosterone Topical from Consumer Reports Health.  -  Jan 4, 2005
Florone), fluocinolone (Derma-Smoothe, Flurosyn, Synalar), fluocinonide (Lidex), flurandrenolide (Cordran), fluticasone (Cutivate), halcinonide (Halog), ... consumerreports.org

Be age-specific with topical steroids for AD.(Dermatologic Therapy) |...  -  Jun 1, 2007
...indication for pediatric AD that don't carry a warning regarding HPA suppression are prednicarbate 0.1% cream and fluticasone 0.05% lotion (Cutivate). ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Ceragenix gets IRB OK for eczema trial in children.  -  Jul 3, 2006
...which received US marketing clearance in April, to Pharmaderm's Cutivate (fluticasone), a commonly-used mid-strength topical steroid approved for use in ... $9.94 - Pharma Marketletter - Alacra Store

New topical antibiotic for impetigo available.(NEWS FROM THE FDA) | …  -  Jun 1, 2007
Bactroban, Cutivate, and Altabax, according to GSK. Combined revenues for the two companies would have totaled $1.5 billion in 2008, and accounted for . ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Melville, NY--Altana Inc. on Monday acquired Consumer Healthcare, …  -  Apr 5, 2006
Altana's PharmaDerm division will manufacture and market the former GSK products, which include Aclovate, Cutivate, Emgel and Oxistat ... $9.94 - Drug Store News-Newsfirst - Alacra Store

Article: Topical steroids unlikely to switch to OTC soon: manufacturer...  -  May 1, 2005
In the United States, GSK sells Cutivate (fluticasone) and Temovate (clobetasol) by prescription, both of which were discussed at the meeting. ... Pay-Per-View - Internal Medicine News - HighBeam Research

Steroid lotion approved for kids.(Products) | Article from Skin &...  -  Jan 1, 2006
Cutivate (fluticasone propionate) lotion, 0.05%, a midpotency steroid lotion, is approved for the relief of t... Pay-Per-View - Skin & Allergy News - HighBeam Research

Treatment options for atopic dermatitis.  -  Feb 15, 2007
There is no evidence that more frequent application of hydrocortisone butyrate 0.1% (Locoid) or fluticasone propionate 0.05% (Cutivate) cream is more ... $4.95 - American Family Physician - ECNext

Research and Markets : Study the global consumer healthcare activities...  -  Jun 23, 2005
The five brands are: Aclovate, Cutivate, Emgel, Oxistat and Temovate and have sales of around $35 million. Elan had licensed the brands from Glaxo Wellcome ... $4.95 - M2 Presswire - ECNext

Atopic Dermatitis; Ceragenix Pharmaceuticals initiates multi-center …  -  Sep 12, 2006
...in a multicenter pediatric clinical study designed to assess the efficacy of EpiCeram compared to Cutivate, a commonly prescribed mid-strength steroid, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Article: Advisory panels: no go on OTC topical steroids.(News)(over...  -  May 1, 2005
In the United States, GSK sells Cutivate (fluticasone) and Temovate (clobetasol) by prescription, both of which were discussed at the meeting. ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Merger and Acquisition Scenario  -  Mar 11, 2006
Temovate (Clobetasol Propionate); Cutivate (Fluticasone Propionate); Betamethasone Dipropionate Cream; Fluocinonide E Cream. Digestive System ... $250.00 - Revere Reports - Revere

fluticasone propionate GlaxoSmithKline supplemental approval, USA ( …  -  Apr 3, 2006
...fluticasone propionate, fluticasone, CCI 18781, SN 410, SN 411MD, FLOVENT, FLIXONASE, FLIXOTIDE, FLONASE, FLUTIVATE, FLUTIDE NASAL, CUTIVATE, RONTILONA, ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Two asthma drugs' efficacy compared.(Pulmonary Medicine) | Article...  -  Oct 15, 2005
Cutivate (fluticasone propionate) cream 0.05%, a topical corticosteroid that was previously approved for use in adults only, has been approved to treat ... Pay-Per-View - Family Practice News - HighBeam Research

New generics.  -  Apr 3, 2006
It is bioequivalent to GlaxoSmithKline's Cutivate Ointment and will be available in 15-, 30-, and 60-gm tubes. Following a temporary suspension, ... $9.94 - Drug Topics - Alacra Store

Competitors by Product Report  -  Dec 16, 2006
Aclovate (Alclometasone Dipropionate); Alclometasone Dipropionate; Betamethasone Dipropionate Cream; Cutivate (Fluticasone Propionate); Fluocinonide E Cream ... $75.00 - Revere Reports - Revere

Ceragenix obtains IRB approval for eczema clinical study.(New...  -  Oct 1, 2006
NJ, will compare the use of EpiCeram[R], a nonsteroidal skin barrier cream that received FDA marketing clearance in April 2006, to Cutivate[R], ... $4.95 - Dermatology Nursing - ECNext

Drug/Medical Device  -  Dec 16, 2006
Cutivate (Fluticasone Propionate), For The Relief Of The Inflammatory And Pruritic Manifestations Of Corticosteroid-Responsive Dermatoses, Pruritus, ... $70.00 - Revere Reports - Revere

Ceragenix obtains IRB approval for eczema clinical study.(New...  -  Oct 1, 2006
N J, will compare the use of EpiCeram[R], a nonsteroidal skin barrier cream that received FDA marketing clearance in April 2006, to Cutivate[R], ... Pay-Per-View - Dermatology Nursing - HighBeam Research

Step-down therapy feasible for stabilized asthma.(Pulmonary Medicine)(...  -  Jul 15, 2006
Cutivate) in a 113-patient multicenter randomized ... after 4 weeks of fluticasone, although the ... therapy, only 4% of patients in the EpiCeram ... Pay-Per-View - Family Practice News - HighBeam Research

GSK fortifies partnerships with pharmacies.(MARKETPLACE 2005/ …  -  Jun 6, 2005
GlaxoSmithKline Consumer Healthcare (GSK) has added five prescription dermatology products to its portfolio. Aclovate, Cutivate, Oxistat and Emgel were all ... Pay-Per-View - Chain Drug Review - HighBeam Research

Signature strengths: achieving your destiny.(On Leadership) | Article...  -  Jun 1, 2005
...a non-steroidal cream, to that of Cutivate[R] cream, a mid-strength topical steroid, in the treatment of moderate-to-severe atopic dermatitis. ... Pay-Per-View - Dermatology Nursing - HighBeam Research

Press Release: Alpharma Launches Halobetasol Propionate Ointment. - …  -  Sep 1, 2005
PR Newswire; March 3, 2003 ; 540 words ... ... rated to Diprolene(R) by Schering and Fluticasone Propionate Ointment 0.005%, AB-rated to Cutivate(R) by ... Pay-Per-View - PR Newswire - HighBeam Research

Factiva Search  -  Nov 15, 2005
2005 NOV 15 - (NewsRx.com) -- PharmaDerm announced the official launch of Cutivate (fluticasone propionate) Lotion, ... © Copyright 2005 Life Science Weekly ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

New drugs.  -  Nov 21, 2005
PharmaDerm, Atlanta, (678) 287-1500, is officially launchinhtdg Cutivate (fluticasone propionate) Lotion, 0.05%. The mid-potency steroid lotion is approved ... $9.94 - Drug Topics - Alacra Store

Disparition irritations cuir chevelu - antibiotique ?  -  Nov 8, 2006
Je n'ai donc plus employé ce produit et ai pris pour me soulager dans l'immédiat du "cutivate" car il se trouve dans un tube en fer. ... Allergique - Allergique (Abonnement)

Press Release: SkinMedica Introduces Desonate(R) (desonide) Gel 0.05 …  -  Jan 8, 2008
Article: Two New Studies Affirm Safety and Efficacy of Cutivate(R) Cream ... PR Newswire; October 19, 1998 ; 700+ words ... ... corticosteroid -- in the ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Manhattan Pharmaceuticals Announces License …  -  Apr 4, 2007
Article: Two New Studies Affirm Safety and Efficacy of Cutivate(R) Cream ... PR Newswire; October 19, 1998 ; 700+ words ... ... corticosteroid -- in the ... Pay-Per-View - PR Newswire - HighBeam Research

Article: Aerospan, Clarinex-D 12-hour tablets.(New & Approved) -...  -  Apr 1, 2006
Article: Cutivate Cream: Indication expanded to pediatric patients ... Formulary; August 1, 1999 ; 422 words ... ... expanded to pediatric patients aged 3 ... Pay-Per-View - Family Practice News - HighBeam Research

Article: Blacks are more likely to survive first stroke.(Neurology)(Br...  -  Dec 1, 2005
Article: Cutivate Cream: Indication expanded to pediatric patients ... Formulary; August 1, 1999 ; 422 words ...Indication expanded to pediatric patients ... Pay-Per-View - Internal Medicine News - HighBeam Research

Topical therapies show promise for treating psoriasis.(PSORIASIS …  -  Oct 1, 2006
Article: New Studies Confirm Safety and Efficacy of Cutivate[R].(for the ... Dermatology Nursing; August 1, 2001 ; 697 words ... ... 005% -- a mid-potency ... Pay-Per-View - Dermatology Nursing - HighBeam Research

Brand Names/Synonyms:
Cutivate is also known by the following brand names and/or synonymsAdvair Diskus 100/50; Advair Diskus 250/50; Advair Diskus 500/50; Cutivate; Flixonase; Flixotide; Flonase; Flovent; Flovent Diskus 100; Flovent Diskus 250; Flovent Diskus 50; Flovent Hfa; Flunase; Fluticasone Propionate

Drug Category:
Cutivate is categorized under the following by the FDA: Anti-allergic Agents; Dermatologic Agents; Bronchodilator Agents; Anti-inflammatory Agents; Adrenergic Agents; ATC:D07AC17; ATC:R01AD08; ATC:R03BA05

Dosage Forms:
METERED-DOSE (AEROSOL)

Absorption:
The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier.

Interactions:
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Chemical IUPAC Name:
[6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propanoate





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