Cyclobenzaprine

This page contains recent news articles, when available, and an overview of Cyclobenzaprine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Cyclobenzaprine
(when available)

Pharmacology and use:
Cyclobenzaprine, closely related to the antidepressant amitriptyline, is used as a skeletal muscle relaxant to reduce pain and tenderness to and improve mobility. Unlike dantrolene, cyclobenzaprine cannot be used to treat muscle spasm secondary to cerebral or spinal cord disease. For use as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions

Mechanism Of Action:
Like the tricyclic antidepressants, cyclobenzaprine exhibits anticholinergic activity, potentiation of norepinephrine, and antagonism of reserpine. Cyclobenzaprine does not directly act on the neuromuscular junction or the muscle but relieves muscle spasms through a central action, possibly at the brain stem level. Cyclobenzaprine binds to the serotonin receptor and is considered a 5-HT2 receptor antagonist that reduces muscle tone by decreasing the activity of descending serotonergic neurons.

News Articles on Cyclobenzaprine

Woman: 'I don't want you looking in my purse,'... on drug possession  -  ‎Dec 27, 2009‎
Crawley gave the deputy a bottle for Cyclobenzaprine and said she had methadone tablets and other narcotics in the bottle, the report said. The Northwest Florida Daily News

Former teacher indicted on sex assault charges  -  ‎Dec 29, 2009‎
...in someone who has stopped taking narcotics, Darvocet: a habit forming pain reliever and Cyclobenzaprine: a muscle relaxant according to www.drugs.com. ... Winnisquam Echo

Medical marijuana attorney Rob Corry: "The future is here"  -  ‎Dec 18, 2009‎
These medications include Copaxone, Gabapentin, Cyclobenzaprine, Meloxicam, Sertraline, Advair, and Mirapex. With the addition of medical marijuana to her ... Westword (blog)

FDA Cuts Food and Drug Restrictions for Parkinson's Medication  -  ‎Dec 15, 2009‎
...dextromethorphan, St. John's wort, mirtazapine, or cyclobenzaprine. The drug may cause increased blood pressure if taken with other MAO inhibitors, ... MedPage Today

Cephalon, Inc. - Pharmaceuticals & Healthcare - Deals and Alliances Profile ...  -  ‎Dec 29, 2009‎
...fentanyl buccal tablets, arsenic trioxide injections, oral transmucosal fentanyl citrate and cyclobenzaprine hydrochloride extended release capsules. ... PRMinds (press release)

Falmouth District Court  -  ‎Dec 19, 2009‎
7 in Bourne, dismissed upon payment of $100 court cost; possessing cyclobenzaprine, dismissed upon payment of $100 court cost; license plate violation to ... Cape Cod Times

Continued Growth At Centron With New Assignments From Cephalon And Acorda ...  -  ‎Nov 10, 2009‎
...is pleased to announce that they have been awarded the agency of record assignment for AMRIX® (Cyclobenzaprine Hydrochloride Extended-Release Capsules) ... PharmaLive.com (press release)

Pivotal Data Published in the Journal Cancer Demonstrate that TREANDA Induced ...  -  ‎Nov 5, 2009‎
The company's proprietary products in the United States include: NUVIGIL® (armodafinil) Tablets [C-IV], TREANDA, AMRIX® (cyclobenzaprine hydrochloride ... Reuters

Cephalon, Inc. to Webcast R&D Day  -  ‎Nov 4, 2009‎
The company's proprietary products in the United States include: NUVIGIL® (armodafinil) Tablets [C-IV], AMRIX® (cyclobenzaprine hydrochloride ... Reuters

Majority of Surveyed Physicians Prescribe Cymbalta and Lyrica for Treatment of ...  -  ‎Oct 21, 2009‎
Surveyed rheumatologists told us that similar percentages of their prescriptions for amitriptyline and cyclobenzaprine are in the first line compared with ... Reuters

Mayo Clinic Proceedings Publishes Study of NUVIGIL in Patients with Shift Work ...  -  ‎Nov 2, 2009‎
The company's proprietary products in the United States include: NUVIGIL, TREANDA(R) (bendamustine hydrochloride) for Injection, AMRIX(R) (cyclobenzaprine ... Reuters

Cephalon Appoints Bob Repella as Senior Vice President of U.S. Pharmaceutical ...  -  ‎Oct 27, 2009‎
AMRIX® (cyclobenzaprine hydrochloride extended-release capsules), FENTORA® (fentanyl buccal tablet) [C-II], TRISENOX® (arsenic trioxide) injection, ... Reuters

Cephalon Net Sales Increase 9% and Net Cash from Operations Surpasses $200 ...  -  ‎Oct 27, 2009‎
The company's proprietary products in the United States include: AMRIX® (cyclobenzaprine hydrochloride extended-release capsules), TREANDA® for Injection, ... Reuters

Slow diagnosis hampers uptake of fibromyalgia drugs  -  ‎Oct 27, 2009‎
Surveyed physicians report slightly greater first-line use of off-patent agents amitriptyline and cyclobenzaprine, which have a comparatively long history ... Medical Marketing and Media

Orleans District Court  -  ‎Oct 19, 2009‎
CHENEY, Aimee T., 25, 110 Serb St., Eastham; possession of Lyrica, possession of cyclobenzaprine, possession of Trazadone, possession of ... Cape Cod Times

Cephalon, Inc. - Pharmaceuticals & Healthcare - Deals and Alliances Profile ...  -  ‎Nov 9, 2009‎
...fentanyl buccal tablets, arsenic trioxide injections, oral transmucosal fentanyl citrate and cyclobenzaprine hydrochloride extended release capsules. ... PR-Inside.com (Pressemitteilung)

Brother of Misty Croslin arrested on drug charge  -  ‎Nov 6, 2009‎
The drugs found in the van include alprazolam, hydrocodone, methadone, cyclobenzaprine and oxycodone, the report stated. Croslin was charged with possession ... Gainesville Sun

Cephalon Net Sales Increase 9% and Net Cash from Operations Surpasses $200 ...  -  ‎Oct 28, 2009‎
The company's proprietary products in the United States include: AMRIX® (cyclobenzaprine hydrochloride extended-release capsules), TREANDA® for Injection, ... PharmaLive.com (press release)

Cephalon Appoints Bob Repella as Senior Vice President of US Pharmaceutical ...  -  ‎Oct 27, 2009‎
TREANDA(R) (bendamustine hydrochloride) for Injection, AMRIX(R) (cyclobenzaprine hydrochloride extended-release capsules), FENTORA(R) (fentanyl buccal ... Trading Markets (press release)

India Ranbaxy gets FDA nod for cyclobenzaprine HCL  -  May 15, 2008
MUMBAI (Reuters) - Indian drugmaker Ranbaxy Laboratories Ltd (RANB.BO) has received approval from the US Food and Drug Administration for muscle relaxant ... Reuters UK

Cyclobenzaprine hydrochloride for fibromyalgia  -  Oct 30, 2007
Cyclobenzaprine is a drug used to relax muscles. Experts do not know exactly how this drug works to improve fibromyalgia. Cyclobenzaprine is chemically ... WebMD

FDA approves Mylan's cyclobenzaprine  -  Feb 6, 2006
WASHINGTON, Feb. 6 (UPI) -- Mylan said Monday it is cleared to sell cyclobenzaprine, the generic equivalent of McNeil's muscle relaxant Flexeril. ... United Press International

Aurobindo gets FDA nod for Cyclobenzaprine  -  Sep 29, 2008
29 Sep, 2008, 1413 hrs IST, PTI. NEW DELHI: Drug firm Aurobindo Pharma has received US Food and Drug Administration (USFDA) approval for marketing ... Economic Times

Cyclobenzaprine (Systemic).  -  Jul 28, 2005
Cyclobenzaprine (sye-kloe-BEN-za-preen) is used to help relax certain muscles in your body. It helps relieve the pain, stiffness, and discomfort caused by ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Cyclobenzaprine Extended-Release Tablets Superior to Placebo in …  -  Feb 18, 2008
By Ed Susman. KISSIMMEE, FL -- February 18, 2008 -- The extended-release formulation of cyclobenzaprine hydrochloride (Amrix) demonstrated superior ability, ... DG News

Aurobindo gets USFDA nod for Cyclobenzaprine hydrochloride  -  Sep 29, 2008
New Delhi (PTI): Drug firm Aurobindo Pharma has received US Food and Drug Administration (USFDA) approval for marketing Cyclobenzaprine hydrochloride ... Hindu

Pittsburgh Post-Gazette business briefs column.  -  Feb 7, 2006
ALSO IN BUSINESS: Mylan Laboratories received Food and Drug Administration approval to market Cyclobenzaprine Hydrochloride tablets, the generic version of ... Free with registration - Pittsburgh Post-Gazette - AccessMyLibrary.com

Aurobindo Pharma gets USFDA nod for two drugs  -  Oct 10, 2008
Cyclobenzaprine is a generic version of MCNEIL -PPC's Flexeril tablets and are indicated to be used for relief of muscle spasm. ... The Hindu

Clinical Perspectives on Pain Management Advances Highlight Day 2  -  Mar 1, 2005
Cyclobenzaprine (Flexeril) monotherapy is as effective in treating acute ... Patients were randomized to receive 5 mg of cyclobenzaprine 3 times daily as ... Medscape

PRESS RELEASE: Cephalon Announces Agreement to Acquire AMRIX  -  Aug 23, 2007
..."Cyclobenzaprine HCl is the most widely prescribed muscle relaxant in the United ... AMRIX is a once-a-day, extended-release version of cyclobenzaprine ... FierceBiotech

… FDA Approval for Cyclobenzaprine Hydrochloride Tablets USP, 5 mg. ...  -  Feb 6, 2006
Mylan Announces FDA Approval for Cyclobenzaprine Hydrochloride Tablets USP, 5 mg. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… announces approval for Cyclobenzaprine Hydrochloride Tablets USP,...  -  Mar 1, 2006
...(ANDA) for Cyclobenzaprine Hydrochloride Tablets USP, 5 mg. CycIobenzaprine Tablets are the AB-rated generic equivalent of McNeil's Flexeril[R] Tablets. ... Free with registration - Pharmaceutical Processing - AccessMyLibrary.com

Woman facing 4 more charges  -  Oct 23, 2007
The bottles were for hydrocodone, locet and cyclobenzaprine, according to court documents. According to documents, Behles is accused of possessing and ... Bismarck Tribune

… Administrative Code - 77 Ill. Adm. Code 790.2805 CYCLOBENZAPRINE …  -  Aug 10, 2005
77 Ill. Adm. Code 790.2805 CYCLOBENZAPRINE HYDROCHLORIDE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

Ranbaxy gets FDA nod for cyclobenzaprine HCL  -  May 15, 2008
Mumbai, May 15: : Indian drugmaker Ranbaxy Laboratories Ltd has received approval from the US Food and Drug Administration for muscle relaxant ... Financial Express

… Management; US FDA grants approval for cyclobenzaprine HCl tablets...  -  Mar 27, 2006
2006 MAR 27 - (NewsRx.com) -- Actavis Group announced that its wholly owned subsidiary, Amide Pharmaceutical, Inc., has received approval from the United ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

… announces approval for Cyclobenzaprine Hydrochloride Tablets USP,...  -  Mar 1, 2006
Mylan announces approval for Cyclobenzaprine Hydrochloride Tablets USP, 5 mg.(Industry News) ... find Pharmaceutical Processing articles. Pay-Per-View - Pharmaceutical Processing - HighBeam Research

Teen charged in student's death released  -  Mar 9, 2007
They also seized a bottle labeled cyclobenzaprine, containing 60 tablets, ... Flexeril is a brand-name muscle relaxer and cyclobenzaprine is the drug's ... New Castle News

… and Eurand Announce Notification of Generic Filing for Cyclobenzapr...  -  Oct 21, 2008
Cephalon and Eurand Announce Notification of Generic Filing for Cyclobenzaprine Hydrochloride Extended-Release Capsules. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

FTC Alleges Cephalon's Deals Blocked Generics from Market  -  Feb 15, 2008
In separate news this week, the firm reported pooled analysis from the two pivotal studies that supported approval showing that Amrix (cyclobenzaprine ... BioWorld Online - BioWorld Online

Mylan confirms first-to-file patent challenge of AMRIX capsules  -  Dec 1, 2008
Cyclobenzaprine HCl ER Capsules, a muscle relaxant introduced to the market in October 2007, had approximately $53 million in sales for the twelve months ... News-Medical.net

Mylan reaches Femara settlement with Novartis  -  Dec 3, 2008
The legal action relates to the filing of an abbreviated new drug application for Cyclobenzaprine Hydrochloride Extended-release Capsules 15 mg and 30 mg, ... Hays Pharma

From Our Readers - Comments & Suggestions 10-22-08  -  Oct 22, 2008
Note: Flexeril [generic name cyclobenzaprine] is a prescription muscle relaxant that works by blocking nerve/pain impulses to the brain. ... ProHealth

Press Release: Cephalon, Inc. Announces Agreement to Acquire AMRIX, …  -  Aug 23, 2007
..."Cyclobenzaprine HCl is the most widely prescribed muscle relaxant in the United ... AMRIX is a once-a-day, extended-release version of cyclobenzaprine ... Pay-Per-View - PR Newswire - HighBeam Research

Sudden spasms following gradual lordosis—the stiff-person syndrome  -  Feb 6, 2006
Her spasms had at that time improved with oral diazepam 5 mg every 6 h as required, and oral cyclobenzaprine 10 mg every 8 h as required. ... Nature.com

For fibromyalgia, which treatments are the most effective?(CLINICAL …  -  Dec 1, 2005
...(1) A meta-analysis of 5 RCTs on cyclobenzaprine, a muscle relaxant chemically related ... Treatment of fibromyalgia with cyclobenzaprine: a meta-analysis. ... Pay-Per-View - Journal of Family Practice - Factiva, from Dow Jones

FDA first-time generics approvals--2006.(Special Report)(Statistical...  -  Feb 19, 2007
Commit lozenges, 2 mg and 4 mg FEBRUARY Cyclobenzaprine Amide Pharmaceutical Flexeril tablets ... It also ... cyclobenzaprine (Flexeril), folic acid 1 mg, ... Pay-Per-View - Chain Drug Review - HighBeam Research

Press Release: Has added Cephalon Inc. to their watch list. - M2 …  -  Feb 15, 2008
News: Data from Two Pivotal Trials of AMRIX, a New Once-Daily Extended-Release ... controlled clinical trials showing that AMRIX (cyclobenzaprine ... Pay-Per-View - M2 Presswire - HighBeam Research

Use of Muscle Relaxants for Musculoskeletal Conditions Reviewed  -  Aug 5, 2008
A meta-analysis of cyclobenzaprine showed that it was superior to placebo for treating fibromyalgia but that it was not as effective as antidepressants. ... Medscape

First-Time Generic Approvals: Flexeril, Plavix, and AndroGel  -  Feb 21, 2006
Cyclobenzaprine is indicated as an adjunct to rest and physical therapy for the relief of muscle spasm associated with acute, painful musculoskeletal ... Medscape

Treatment of acute low back pain: use of medications: reduction and …  -  Feb 1, 2005
In a meta-analysis of the cyclobenzaprine literature, Browning and associates ... Commonly prescribed muscle relaxants include cyclobenzaprine (5- and 10-mg ... $4.95 - Journal of Musculoskeletal Medicine - ECNext

DJ HUGIN NEWS/Eurand Reports Recent Developments and Second …  -  Aug 7, 2008
EUR-1002 -- Amrix(r) (cyclobenzaprine HCl) * On June 17, 2008, the United States Patent and Trademark Office (USPTO) granted the Company US patent No. ... financial.de

Fibromyalgia update.(drug)  -  Jul 1, 2006
It included three cyclobenzaprine studies, even though cyclobenzaprine is classified as ... Treatment of fibromyalgia with cyclobenzaprine: a meta-analysis. ... $4.95 - Bandolier - ECNext

Narrative of The Stress Cycle By Jonathan Strickling  -  Dec 30, 2007
Upon his examination he prescribed Cyclobenzaprine as a muscle relaxer. ... Dr. Siu prescribed more Cyclobenzaprine, which I took occasionally. ... HealthCentral.com

Press Release: Arena Pharmaceuticals Announces Positive Phase 2b …  -  Dec 13, 2005
FLEXERIL(R) (cyclobenzaprine HCl) 5 mg tablets, the newly approved muscle relaxant ... shelves across the nation. FLEXERIL 5 mg tablets are a new lower-dose ... Pay-Per-View - PR Newswire - HighBeam Research

Generics makers keep new products coming.(RX/GENERICS)(Statistical …  -  Sep 17, 2007
Glyburide-Metformin HCl $112943343.72 Teva USA Nabumetone $110522319.55 Danbury Cyclobenzaprine HCl $109782263.07 Mylan Phenytoin Sodium Extended ... Free with registration - Chain Drug Review - AccessMyLibrary.com

A patient with abdominal pain and markedly elevated transaminase...  -  Dec 13, 2005
Her medications also included alprazolam and cyclobenzaprine taken intermittently ... In this patient, medications on admission included cyclobenzaprine and ... Nature.com

Drug-induced interference of tricyclic antidepressant assays.(Drug...  -  Feb 1, 2006
A recent review has examined the effect of cyclobenzaprine on TCA assays. (1). The newer atypical antipsychotic quetiapine (Seroquel) has a 3-ringed ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

United States top 250 generic drugs by retail sales and manufacturer...  -  Apr 23, 2007
Morphine sulfate $48214095.44 Pliva Cyclobenzaprine HCI $47998641.12 Watson Labs Bupropion HCI $47941787.58 Teva USA Metformin HCI $47908616.18 Teva USA ... $20.00 - Chain Drug Review - Alacra Store

Straits Gold Pty Ltd withdraws offer for Goldminco Corp-Tenements(2) ...  -  Sep 2, 2008
Zevalin; Johnson & Johnson: Duragesic; McNeil Consumer & Specialty Pharmaceuticals: Flexeril, Oros Cyclobenzaprine; Novartis Phormaceuticals… ... Pay-Per-View - deals - Alacra Store

Press Release: Six-Month Study Evaluated Effectiveness of Aripiprazole...  -  May 25, 2006
FLEXERIL(R) (cyclobenzaprine HCl) 5 mg tablets, the newly approved muscle relaxant ... shelves across the nation. FLEXERIL 5 mg tablets are a new lower-dose ... Pay-Per-View - PR Newswire - HighBeam Research

THE 'BUPE' FIX  -  Dec 16, 2007
The medical examiner initially found in Bessette's body a high level of alcohol and a muscle relaxer, cyclobenzaprine, but did not determine a cause of ... Pay-Per-View - The Sun - ProQuest Archiver

Methuen police nab four in pot bust  -  Mar 26, 2008
Cyclobenzaprine is a muscle relaxant that works by blocking nerve impulses or pain sensations that are sent to the brain. The drug is used in the treatment ... Eagle Tribune

Press Release: New River Pharmaceuticals Provides Detail on A01 …  -  Jun 18, 2006
FLEXERIL(R) (cyclobenzaprine HCl) 5 mg tablets, the newly approved muscle relaxant ... shelves across the nation. FLEXERIL 5 mg tablets are a new lower-dose ... Pay-Per-View - PR Newswire - HighBeam Research

Useful Treatments for Fibromyalgia Syndrome  -  Mar 1, 2005
Strong evidence for efficacy was found for treatment with amitriptyline, cyclobenzaprine, exercise, cognitive behavior therapy, and patient education. ... AAFP News Now

Eurand to Be Issued US Patent for Amrix(R)  -  Jun 3, 2008
Eurand's patent will include claims covering Amrix(r) (cyclobenzaprine ... According to IMS, Cyclobenzaprine HCl is the most widely prescribed muscle ... RedOrbit

Eurand's formulations stack up at the FDA  -  Mar 11, 2008
Also employing the Diffucaps technology is EUR-1002, a once-daily formulation of the skeletal muscle relaxant cyclobenzaprine hydrochloride that was ... In-PharmaTechnologist.com

Eurand Reports Fourth Quarter and Year-end 2007 Key Achievements …  -  Mar 6, 2008
Eurand also provided an update on Amrix(r) (cyclobenzaprine HCl), the only once-daily skeletal muscle relaxant which Eurand developed that is currently ... Lifescience-online

Judge John S. McCann  -  Mar 1, 2007
...possession of psilocybin, amended from possession of psilocybin with intent to distribute (second or subsequent offense), possession of cyclobenzaprine, ... $1.95 - Worcester Telegram Gazette - NewsBank

United States top 250 generic pharmaceuticals by sales, and …  -  Feb 4, 2008
Trinessa 89915565 148 Mylan Cyclobenzaprine HCl 88797108 149 Teva USA Tramadol HCl 88725730 150 Watson Labs. Metformin HCl 88576105 151 Mylan Meloxicam ... $20.00 - Chain Drug Review - Alacra Store

Global top 300 multisource generic pharmaceuticals by sales, …  -  Apr 28, 2008
Ranitidine HCI 49884054410 226 Pliva Cyclobenzaprine HCI 50111056303 227 Upsher-Smith Vandazole 00245086070 228 Par Pharm. ... $20.00 - Chain Drug Review - Alacra Store

Choongwae Holdings Co Ltd acquires a minority stake in Three Seven …  -  Jun 26, 2008
Therapeutic Indication Angina LSA…cyclobenzaprine immediate-release (CIR) taken three times a day in alleviating…placebo, and CIR ## mg three time s daily). ... Pay-Per-View - deals - Alacra Store

Top 300 multisource generics by manufacturer and NDC11 number.(RX/ …  -  Apr 28, 2008
Ranitidine HCI 49884054410 226Pliva Cyclobenzaprine HCI50111056303 227Upsher-SmithVandazole 00245086070 228Par Pharm. Cabergoline49884067314 229Apotex ... Pay-Per-View - Chain Drug Review - HighBeam Research

2005 Annual Report of the American Association of Poison Control …  -  Oct 1, 2006
370 70 yr acetaminophen/hydrocodone 371 70 yr acetaminophen/hydrocodone 372 p 33 yr acetaminophen/hydrocodone acetaminophen cyclobenzaprine (A) 373 41 ... Free with registration - Clinical Toxicology - AccessMyLibrary.com

Market Live from BSE - NSE, Latest Market Commentary | Economic …  -  Oct 10, 2008
12:10 pm: Aurobindo Pharma has received final approval from the US Food & Drug Administration to manufacture and market cyclobenzaprine hydrochloride ... Economic Times

Integrative therapy for fibromyalgia: possible strategies for an …  -  Feb 1, 2005
Cyclobenzaprine, a commonly used muscle relaxant, has also shown efficacy in improving sleep in many patients. (11) Recent release of a 5 mg dose permits ... $4.95 - Southern Medical Journal - ECNext

Useful treatments for fibromyalgia syndrome.(Patient Oriented...  -  Feb 1, 2005
Strong evidence for efficacy was found for treatment with amitriptyline, cyclobenzaprine, exercise, cognitive behavioral therapy, and patient education. ... $4.95 - Journal of Family Practice - ECNext

Ascenzi v. Diaz, No. 3:CV-05-1656 (MDPa. 03/30/2007)  -  Mar 30, 2007
Dr. Diaz then prescribed Ibuprofen 600 mg twice daily, Acetaminophen 325 mg daily, and Cyclobenzaprine (a muscle relaxant). Dr. Diaz stated that because ... $2.95 - U.S. District Court, Middle District of... - VersusLaw

Antidepressants and antiepileptic drugs for chronic non-cancer pain.  -  Feb 1, 2005
Cyclobenzaprine, a muscle relaxant that structurally is a tricyclic agent, also has shown modest efficacy in patients with fibromyalgia. (34) ... $4.95 - American Family Physician - ECNext

Gabapentin as a Potential Option for Treatment of Sciatica: Case...  -  Jun 11, 2007
Physical therapy was recommended, and the patient was prescribed oral hydrocodone 10 mg-acetaminophen 1000 mg every 6 hours and oral cyclobenzaprine 10 mg ... Medscape

Wal-Mart $4 Generics Program Launched In Colorado.  -  Nov 27, 2006
Allergy Loratadine 10MG TAB Loratadine 5MG/5ML SYP* Analgesics Antipy/Benzo Otic SOL Baclofen 10MG TAB Cyclobenzaprine 10MG TAB Cyclobenzaprine 5MG TAB ... Free with registration - PR Newswire - AccessMyLibrary.com

Be conservative with neck pain, experts urge: no history of trauma, …  -  Jun 1, 2005
405 patients with low back or neck pain, participants were randomly ... cyclobenzaprine or placebo. Dr. Borenstein noted that the cyclobenzaprine ... ... Pay-Per-View - Family Practice News - HighBeam Research

Man presents with sudden onset ocular congestion  -  Mar 15, 2007
The patient had taken an excessive amount of cyclobenzaprine (Flexeril) 1 week before presentation. He was found unconscious 12 hours later in his home. ... OSN SuperSite

Low-dose drug combos best for sciatica, low back pain.(Rheumatology)...  -  May 15, 2005
Dr. Borenstein noted that the cyclobenzaprine outperformed placebo in three primary, patient-rated end points: relief from pain at the start of the day, ... Pay-Per-View - Internal Medicine News - HighBeam Research

: Key Developments  -  Dec 23, 2008
This patent claims extended-release formulations containing the muscle relaxant cyclobenzaprine, including AMRIX (Cyclobenzaprine Hydrochloride ... MSN Money

Briefs: US Airways traffic falls as it cuts flights  -  Feb 7, 2006
Cyclobenzaprine tablets are the generic equivalent of McNeil's Flexeril tablets. The US sales for the five mg. strength of Flexeril were about $93 million ... Pittsburgh Tribune-Review

Cephalon and Eurand File Patent Infringement Lawsuit Against Mylan …  -  Nov 26, 2008
This patent claims extended-release formulations containing the muscle relaxant cyclobenzaprine, including AMRIX(R) (Cyclobenzaprine Hydrochloride ... Genetic Engineering News - Genetic Engineering News (press release)

Firefighter Deaths from Prescription Medications: Two Case Studies  -  Dec 1, 2008
The death certificate and autopsy listed “acute intoxication by the combined effects of propoxyphene (Darvon®) and cyclobenzaprine (Flexeril®)� as the cause ... FireEngineering.com

Subcutaneous Trigger Point Causing Radiating Postsurgical Pain  -  Mar 17, 2008
Myofascial pain syndrome was diagnosed, and acetaminophen with codeine and cyclobenzaprine hydrochloride were prescribed. The analgesic was provided for the ... Archives of Dermatology

How effective are muscle relaxers?  -  Aug 10, 2008
Cyclobenzaprine hcl has the most recent and largest clinical trials ... Cyclobenzaprine and carisoprodol were compared in the treatment of patients with ... MedIndia

Data From Two Pivotal Trials Of AMRIX, A New Once-Daily Extended- …  -  Feb 15, 2008
AMRIX had similar efficacy to cyclobenzaprine immediate-release (CIR) taken three times a day in alleviating acute muscle spasm associated with lower back ... Medical News Today - Medical News Today (press release)

MisionesOnline - Noticias de Misiones Argentina  -  Apr 30, 2007
El nosocomio ha recibido una donación de aproximadamente cien mil comprimidos de Cyclobenzaprine ClH, cien mil de Citalopram 40 mg y otros cien mil de ... Misiones OnLine

Antidepressants and antiepileptic drugs for chronic non-cancer pain.  -  Feb 1, 2005
Cyclobenzaprine, a muscle relaxant that structurally is a tricyclic agent, also has shown modest efficacy in patients with fibromyalgia. (34) ... Pay-Per-View - American Family Physician - Factiva, from Dow Jones

[U] State v. White, 133 Wash.App. 1035 (Wash.App.Div.3 06/29/2006)  -  Jun 29, 2006
...information on the internet, Mr. Nessan was able to identify the pills as prescription level ibuprofen (400 mg) and cyclobenzaprine, both legend drugs. ... $2.95 - Washington Court of Appeals - VersusLaw

Arkansas Workers' Compensation Decisions - BOLT v. BAILEY PAINT CO …  -  Sep 17, 2008
The claimant was also prescribed Flexeril, Lortab, Hydrocodone, and Cyclobenzaprine. Dr. William Warren examined the claimant on June 9, 2006, ... Pay-Per-View - Arkansas Workers' Compensation Decisions - Loislaw

Press Release: Mylan Confirms First-to-File Patent Challenge Relating...  -  Dec 1, 2008
Cyclobenzaprine HCl ER Capsules, a muscle relaxant introduced to the market in October 2007, had approximately $53 million in sales for the twelve months ... Pay-Per-View - PR Newswire - HighBeam Research

Mylan confirms first-to-file Amrix patent challenge.  -  Dec 8, 2008
Cyclobenzaprine, a muscle relaxant introduced to the market in October 2007, had around $53.0 million in sales for the 12 months ending September 30 and ... $9.94 - Pharma Marketletter - Alacra Store

Companies sue Mylan over generic Amrix  -  Dec 2, 2008
The companies say their versions of cyclobenzaprine hydrochloride would not infringe on the Amrix patents. Citing data from IMS Health, Mylan said Amrix ... $2.95 - Observer-Reporter - NewsBank

Press Release: Barr Confirms Patent Challenge of Amrix(R) Extended- …  -  Nov 26, 2008
Amrix (cyclobenzaprine hydrochloride) extended-release capsules, 15mg and 30mg had annual sales of approximately $53 million in the U.S., based on IMS sales ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Cephalon and Eurand File Patent Infringement Lawsuit …  -  Nov 26, 2008
This patent claims extended-release formulations containing the muscle relaxant cyclobenzaprine, including AMRIX(R) (Cyclobenzaprine Hydrochloride ... Pay-Per-View - PR Newswire - HighBeam Research

Suppliers keep expanding scope of lines.(RX/Generic Drugs)(Amneal …  -  Jun 30, 2008
Cyclobenzaprine HC1 tablets USR 10 mg, are an AB-rated therapeutically equivalent alternative to Flexeril (McNeil Consumer Healthcare) and are indicated as ... Pay-Per-View - Chain Drug Review - HighBeam Research

Press Release: Cephalon Announces Issuance of Patent for AMRIX. - PR ...  -  Jun 17, 2008
U.S. Patent and Trademark Office has issued a pharmaceutical formulation patent for AMRIX(R) (Cyclobenzaprine Hydrochloride Extended-Release Capsules). ... Pay-Per-View - PR Newswire - HighBeam Research

Loislaw Federal District Court Opinions - BRISCOE v. MOSES (WDVa. 10-...  -  Oct 22, 2007
Dr. Moses indicates that, prior to his incarceration, Briscoe was prescribed Naprosyn, Tramodol, Flexeril, and Cyclobenzaprine for his osteoarthritis ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Press Release: Has added Cephalon Inc. to their watch list. - M2 …  -  Feb 15, 2008
AMRIX had similar efficacy to cyclobenzaprine immediate-release (CIR) taken three times a day in alleviating acute muscle spasm associated with lower back ... Pay-Per-View - M2 Presswire - HighBeam Research

Suppliers keep expanding scope of lines.  -  Jun 30, 2008
Cyclobenzaprine HC1 tablets USR 10 mg, are an AB-rated therapeutically equivalent alternative to Flexeril (McNeil Consumer Healthcare) and are indicated as ... $9.94 - Chain Drug Review - Alacra Store

FDA tentative generics approvals--2005.(Special Report)(Illustration)  -  Feb 27, 2006
200 mg Zydus Pharmaceuticals USA Inc. OCTOBER Cyclobenzaprine HCl tablets USP, 5 Amide Pharmaceutical Inc. mg Gatifloxacin tablets 200 mg and 400 Teva ... Free with registration - Chain Drug Review - AccessMyLibrary.com

Loislaw Federal District Court Opinions - KELLOGG v. ASTRUE (Ariz. 3-...  -  Mar 10, 2008
...(Id.) Dr. Beck increased Plaintiff's dosage of Nortriptyline, continued Salsalate, and prescribed Cyclobenzaprine because "much of her pain seems muscular. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

FDA tentative generics approvals--2005.(Special Report)(Illustration)...  -  Feb 27, 2006
200 mg Zydus Pharmaceuticals USA Inc. OCTOBER Cyclobenzaprine HCl tablets USP, 5Amide Pharmaceutical Inc. mg Gatifloxacin tablets 200 mg and 400 Teva ... Pay-Per-View - Chain Drug Review - HighBeam Research

Herniated Nucleus Pulposus (Slipped Disk)  -  May 12, 2008
A combination of nonsteroidal anti-inflammatory drugs and muscle relaxants -- such as cyclobenzaprine (Flexeril), diazepam (Valium), carisoprodol (Soma), ... New York Times

Cervical spondylosis  -  Feb 27, 2008
Taking muscle relaxants, such as methocarbamol (Robaxin) or cyclobenzaprine (Flexeril), particularly if neck muscle spasms occur. ... CNN

Spasticity - Symptoms, Causes, Tests - NY Times Health Information  -  Mar 5, 2007
Medicines for spasticity include baclofen, tizanidine, cyclobenzaprine, and benzodiazepines. In rare cases, a pump may be inserted into the spinal fluid to ... New York Times

Back Pain - Low Medications - Back Pain - Low Health Information - NY...  -  May 5, 2008
A combination of nonsteroidal anti-inflammatory drugs and muscle relaxants -- such as cyclobenzaprine (Flexeril), diazepam (Valium), carisoprodol (Soma), ... New York Times

Loislaw Federal District Court Opinions - THOMAS v. ASTRUE (Minn. 7-7...  -  Jul 7, 2008
The Plaintiff was then taking Cyclobenzaprine, Fluoxepine, Hydrochlorothiazide, Hydrocodone, and Vitamin B12 injections. [T. 130-31]. In September of 2006, ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Par begins shipment of pravastatin tablets.(Industry News) | Article...  -  Nov 1, 2006
Article: Mylan announces approval for Cyclobenzaprine Hydrochloride ... Pharmaceutical Processing; March 1, 2006 ; 509 words . ... Pay-Per-View - Pharmaceutical Processing - HighBeam Research

You know what makes me sick?; It took doctors years to figure out my ...  -  May 27, 2007
THE YEAR I was diagnosed with celiac disease, I wrote the following on a page of my journal: "Relafen, Famotidine/Pepcid, Lorazepam, Cyclobenzaprine, Vioxx, ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

[U] Bellamy v. Director, OWCP, Intermarine USA, 199 Fed.Appx. 808...  -  Sep 28, 2006
Second, the Revco bill for Cyclobenzaprine and Hydrocodone did not state why the medications were prescribed. Third, Bellamy's request for mileage ... $2.95 - U.S. Court of Appeals, Eleventh Circuit - VersusLaw

Bloomberg Printer-Friendly Page  -  Jun 3, 2008
The company's proprietary products in the United States include: TREANDA(R) (bendamustine hydrochloride) for injection, AMRIX(R) (Cyclobenzaprine ... Bloomberg

Bitter brew of pain and fatigue hard to beat - FAMILY MEDICINE  -  Jan 11, 2005
Cyclobenzaprine (Flexeril), a muscle relaxant, and certain seizure medications also have been effective in some cases. ... Pay-Per-View - Star-Ledger - Factiva, from Dow Jones

A case of nephrogenic fibrosing dermopathy/nephrogenic systemic …  -  Jul 31, 2006
The patient's medications upon transfer from the other hospital included metoclopramide, lansoprazole, sertraline, cyclobenzaprine, oxycodone, diazepam, ... Nature.com

Brand Names/Synonyms:
Cyclobenzaprine is also known by the following brand names and/or synonymsCyclobenz; Cyclobenzaprine; Cyclobenzaprine Hcl; Flexeril; Flexiban; MK-130; Proeptatriene; Proheptatriene; RP-9715

Drug Category:
Cyclobenzaprine is categorized under the following by the FDA: Tranquilizing Agents; Muscle Relaxants; Antidepressants; Skeletal Muscle Relaxants; ATC:M03BX08

Dosage Forms:
"D"-shaped, film coated tablets

Absorption:
Well absorbed after oral administration

Interactions:
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Chemical IUPAC Name:
3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine





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