Demeclocycline

This page contains recent news articles, when available, and an overview of Demeclocycline but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Demeclocycline (when available)

Pharmacology and use:
Demeclocycline is a tetracycline antibiotic that is commonly prescribed by medical doctors for infections and to treat acne. It may also be used to treat urinary tract infections, gum disease, and other bacterial infections such as gonorrhea and chlamydia. Demeclocycline is also used commonly as a prophylactic treatment for infection by Bacillus anthracis (anthrax). It is also effective against Yersinia pestis and malaria and is also prescribed for the treatment of Lyme disease. Demeclocycline inhibits cell growth by inhibiting translation. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Cells become resistant to Demeclocycline by at least two mechanisms: efflux and ribosomal protection. In efflux, a resistance gene encodes a membrane protein that actively pumps Demeclocycline out of the cell. This is the mechanism of action of the tetracycline resistance gene on the artificial plasmid pBR322. In ribosomal protection, a resistance gene encodes a protein which binds to the ribosome and prevents Demeclocycline from acting on the ribosome. For infections caused by the following microorganisms: Rickettsiae: (Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsial pox, tick fevers). M.pneumoniae (PPLO, Eaton agent). Agents of psittacosis and ornithosis. Agents of

Mechanism Of Action:
Demeclocycline inhibits cell growth by inhibiting translation. It binds to the site of the ribosome. The binding is reversible in nature. Demeclocycline is lipophilic and can easily pass through the cell membrane or passively diffuses through porin channels in the bacterial membrane.

News Articles on Demeclocycline

Learn about Demeclocycline from Consumer Reports Health.  -  Jan 10, 2005
Demeclocycline is used to treat bacterial infections including pneumonia and other respiratory tract infections; acne; and infections of skin, genital, ... consumerreports.org

… Laboratories.(Generics Notebook )(demeclocycline HCl tablets...  -  Jan 17, 2005
Barr Laboratories received approval and began shipment of demeclocycline HCl tablets USP, in 150 mg and 300 mg doses. The drug is the generic equivalent of ... Free with registration - Drug Store News - AccessMyLibrary.com

How to take Demeclocycline from Consumer Reports Health.  -  Jan 10, 2005
...tell your doctor and pharmacist if you are allergic to demeclocycline, tetracycline, minocycline, doxycycline, or any other medications. ... consumerreports.org

Generic Drugs; Approval granted for Demeclocycline Hydrochloride …  -  Jan 23, 2005
2005 JAN 23 - (NewsRx.com & NewsRx.net) -- Barr Pharmaceuticals, Inc., (BRL) announced that its subsidiary, Barr Laboratories, Inc., has received approval ... Pay-Per-View - Medical Letter on the CDC & FDA - Factiva, from Dow Jones

TETRACYCLINE (CLASS) (Oral route, Parenteral route).(Drug overview)  -  May 1, 2007
Demeclocycline, doxycycline, and minocycline also may be used for other ... Some doctors may prescribe demeclocycline for certain patients who retain (keep) ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

This information applies to the following medicines:  -  Feb 1, 2006
Demeclocycline, doxycycline, and minocycline also may be used for other problems ... For demeclocycline For (oral) dosage form (tablets): For bacterial or ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Tetracyclines (Systemic).(anti acne agent overview)(Drug overview)  -  Aug 1, 2006
Demeclocycline, doxycycline, and minocycline also may be used for other problems ... For demeclocycline For (oral) dosage form (tablets): For bacterial or ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Suppliers keep expanding scope of lines.  -  Jun 30, 2008
Demeclocycline HCI tablets USE in strengths of 150 mg and 300 mg, are an AB-rated, therapeutically equivalent alternative to Declomycin (Stonebridge Pharma) ... $9.94 - Chain Drug Review - Alacra Store

Suppliers keep expanding scope of lines.(RX/Generic Drugs)(Amneal …  -  Jun 30, 2008
Demeclocycline HCI tablets USE in strengths of 150 mg and 300 mg, are an AB-rated, therapeutically equivalent alternative to Declomycin (Stonebridge Pharma) ... Pay-Per-View - Chain Drug Review - HighBeam Research

Article: Generics makers keep product pipeline moving.(RX/GENERIC …  -  Sep 25, 2006
...manufacture primidone tablets (50/250 mg), cyclobenzaprine tablets (10 mg) and demeclocycline tablets (150/300 mg). Demeclocycline HCI tablets USE ... ... Pay-Per-View - Chain Drug Review - HighBeam Research

DRUG CAPSULE WHAT YOU SHOULD KNOW  -  Jul 17, 2006
Interactions: Tell your doctor if you drink alcohol or are taking any other medications, particularly carbamazepine, chlorpropamide, demeclocycline, ... $2.95 - Milwaukee Journal Sentinel - NewsBank

DRUG CAPSULE WHAT YOU SHOULD KNOW | Article from The …  -  Jul 17, 2006
Interactions: Tell your doctor if you drink alcohol or are taking any other medications, particularly carbamazepine, chlorpropamide, demeclocycline, ... Pay-Per-View - Milwaukee Journal Sentinel - HighBeam Research

How to take Aminolevulinic Acid Topical from Consumer Reports Health.  -  Jan 10, 2007
...and nausea; sulfa antibiotics; and tetracycline antibiotics such as demeclocycline (Declomycin), doxycycline (Doryx, Vibramycin), minocycline (Dynacin, ... consumerreports.org

How to take Tretinoin from Consumer Reports Health.  -  Jan 6, 2008
...methylprednisolone (Medrol), and prednisone (Deltasone); tetracycline antibiotics such as demeclocycline (Declomycin), doxycycline (Monodox, Vibramycin, ... consumerreports.org

How to take Isotretinoin from Consumer Reports Health.  -  Jan 1, 2007
...methylprednisolone (Medrol), and prednisone (Deltasone); tetracycline antibiotics such as demeclocycline (Declomycin), doxycycline (Monodox, Vibramycin, ... consumerreports.org

How to take Molindone from Consumer Reports Health.  -  Jan 11, 2008
...phenytoin (Dilantin); sedatives; sleeping pills; tetracycline antibiotics such as demeclocycline (Declomycin), doxycycline (Doryx, Monodox, Vibramycin), ... consumerreports.org

Bismuth Subsalicylate.(Drug overview)  -  Feb 1, 2007
Tetracycline antibiotics (examples: tetracycline, doxycycline, demeclocycline, methacycline, minocycline) * Warfarin (Coumadin(R)) Warnings: ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Minocycline (Dental).  -  Oct 27, 2005
...unusual or allergic reaction to minocycline or any other tetracycline medicine (such as doxycycline, demeclocycline, oxytetracycline, or tetracycline). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

How to take Desmopressin Nasal from Consumer Reports Health.  -  Jan 1, 2008
...carbamazepine (Tegretol); chlorpromazine (Thorazine, Sonazine); chlorpropamide (Diabinese); clofibrate; demeclocycline (Declomycin); fludrocortisone; ... consumerreports.org

Clinical Review: Hyponatraemia.  -  Sep 21, 2007
If patients are unable to tolerate fluid restriction, demeclocycline, which acts on the kidney to inhibit ADH action, may be commenced, but it can cause ... Free with registration - GP - AccessMyLibrary.com

How to take Acitretin from Consumer Reports Health.  -  Jan 8, 2006
...do not take methotrexate (Rheumatrex, Trexall) or tetracycline antibiotics such as demeclocycline (Declomycin), doxycycline (Doryx, Vibramycin), ... consumerreports.org

New generics.(Rx)  -  Feb 7, 2005
Demeclocycline hydrochloride tablets, a generic alternative to ESP Pharma's Declomycin Tablets, are available in 150-mg and 300-mg strengths for treating ... Free with registration - Drug Topics - AccessMyLibrary.com

The Vaptans Cast a Wide Net for Potential Therapeutic Uses  -  May 9, 2008
...approaches in hyponatremia, such as severe water restriction, furosemide (Lasix), salt supplementation, urea, and demeclocycline (Declomycin). ... MedPage Today

How to take Heparin Injection from Consumer Reports Health.  -  Jan 8, 2007
...indomethacin (Indocin); phenylbutazone (Azolid) (not available in the US); quinine; and tetracycline antibiotics such as demeclocycline (Declomycin), ... consumerreports.org

Tetracyclines (Ophthalmic).  -  Jul 28, 2005
...such as demeclocycline (eg, Declomycin), doxycycline (eg, Vibramycin), methacycline (eg, Rondomycin), minocycline (eg, Minocin), or oxytetracycline (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Minocycline (Dental).(Drug overview)  -  May 1, 2006
...unusual or allergic reaction to minocycline or any other tetracycline medicine (such as doxycycline, demeclocycline, oxytetracycline, or tetracycline). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Sun Herald : Photosensitive medicines listed  -  Aug 23, 2007
...cefazolin (Ancef); ceftazidime (Fortaz); ciprofloxacin (Cipro); cycloserine (Seromycin); dapsone demeclocycline (Declomycin); doxycycline (Vibramycin); ... $2.95 - Sun Herald - NewsBank

Antiacne agent, topical Meclocycline Tetracycline Antibacterial,...  -  May 1, 2006
...such as chlortetracycline for the eye (eg, Aureomycin); demeclocycline (eg, Declomycin); doxycycline (eg, Vibramycin); methacycline (eg, Rondomycin); ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Antibiotics for Acute Purulent Rhinitis? 'S not a Good Idea  -  Sep 29, 2006
Several different antibiotics were studied: demethylchlortetracycline (demeclocycline, Declomycin® and others), amoxicillin (Amoxil® and others), ... Free with registration - Internal Medicine Alert - AccessMyLibrary.com

Factiva Search  -  Jan 17, 2005
Generic Drugs; Approval granted for Demeclocycline Hydrochloride tablets. 17 January, 2005 Health & Medicine Week. 2005 JAN 17 - (NewsRx.com & NewsRx.net) ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Press of Atlantic City, The : Question & Answer from the pharmacy:...  -  Aug 27, 2007
...cefazolin (An-cef); ceftazidime (Fortaz); ciprofloxacin (Cipro); cycloserine (Seromycin); dapsone demeclocycline (Declomycin); doxycycline (Vibramycin); ... $2.95 - Press of Atlantic City, The - NewsBank

Tetracyclines (Ophthalmic).(Antibacterial agent overview)(Drug...  -  Aug 1, 2006
...such as demeclocycline (eg, Declomycin), doxycycline (eg, Vibramycin), methacycline (eg, Rondomycin), minocycline (eg, Minocin), or oxytetracycline (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Factiva Search  -  Jan 19, 2005
Barr Pharmaceuticals, Inc. Approval granted for Demeclocycline Hydrochloride tablets. 19 January, 2005 Biotech Week. 2005 JAN 19 - (NewsRx.com & NewsRx.net) ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Tetracycline Periodontal Fibers (Dental).  -  Aug 1, 2006
...unusual or allergic reaction to tetracycline or any other tetracycline medicine (such as doxycycline, demeclocycline, oxytetracycline, or minocycline). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Factiva Search  -  Jan 18, 2005
Generic Drugs; Approval granted for Demeclocycline Hydrochloride tablets. 18 January, 2005 Science Letter. 2005 JAN 18 - (NewsRx.com & NewsRx.net) -- Barr ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

메디팜뉴스 - �?�약전문 1등 �?�터넷 신문 (주소창�? 한글로 '메디팜뉴스'를...  -  Dec 28, 2007
...�? 품목�?� �?진취하�?� �?�메�?�로사�?��?�린(demeclocycline), 톨�?사톤(toloxatone), 사 퀴나비르(saquinavir), 마프로틸린 HCI(maprotiline HCI) 등 4개 성분 제품�?� �?진 ... 메디팜뉴스

Factiva Search  -  Jan 17, 2005
Generic Drugs; Approval granted for Demeclocycline Hydrochloride tablets. 17 January, 2005 Anti-Infectives Week. 2005 JAN 17 - (NewsRx.com & NewsRx.net) ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

::: 건강�?� 보�?�는 대한민국 대표 �?�료신문 메디컬투�?��?� :::  -  Sep 29, 2007
...세균 �?염�? 따위�? 쓰는 합성 페니실린�?� 암피실린(ampicillin), 디�?��?사실 린(dicloxacillin), 옥사실린(oxacillin), �?�메�?�로사�?��?�린(demeclocycline) 등�?� 있다. ... 메디컬투�?��?�

Oregon Regulations - 850-060-0226 Naturopathic Formulary by …  -  Feb 1, 2006
...(i) Sulfonamide/Trimethoprim/Sulfones; (H) Tetracyclines**; (i) Demeclocycline Hydrochloride; (ii) Doxycycline; (iii) Minocycline; (iv) Oxytetracycline; ... Pay-Per-View - Oregon Regulations - Loislaw

Georgia Code - 16-13-71. (a) A "dangerous drug" means any drug other ...  -  Aug 4, 2005
...(244) Deferoxamine; (244.5) Delavirdine; (245) Demecarium; (246) Demeclocycline; (247) Demethylchlortetracycline; (248) Deoxyribonuclease, Pancreatic; ... Pay-Per-View - Georgia Code - Loislaw

Treatment of oncologic emergencies.(Clinical report)  -  Dec 1, 2006
...(1) Demeclocycline (Declomycin) is recommended for persistent hyponatremia or for outpatient treatment of minor symptoms. (1,21) HEMATOLOGIC ... $4.95 - American Family Physician - ECNext

Oregon Regulations - 850-060-0225 Naturopathic Formulary …  -  Feb 1, 2006
...(101) Demeclocycline Hydrochloride; (102) Desmopressin; (103) Desoxyribonuclease; (104) Dexamethasone; (105) Dextran; (106) Dextromethorphan; ... Pay-Per-View - Oregon Regulations - Loislaw

Brand Names/Synonyms:
Demeclocycline is also known by the following brand names and/or synonymsBioterciclin; Clortetrin; DMCT; Declomycin; Deganol; Demeclociclina [Inn-Spanish]; Demeclocycline; Demeclocycline Hcl; Demeclocycline Hydrochloride; Demeclocycline [Usan:Ban]; Demeclocyclinum [Inn-Latin]; Demeclor; Demethylchlorotetracycline; Demethylchlortetracyclin; Demethylchlortetracycline; Demethylchlortetracycline Base; Demethylchlortetracycline Hydrochloride; Demethylchlortetracyclinum; Demetraclin; Diuciclin; Elkamicina; HSDB 3051; Ledermycin; Ledermycin Hydrochloride; Methylchlorotetracycline; Mexocine; Novotriclina; Perciclina; Sumaclina; Tri-Demethylchlortetracycline

Drug Category:
Demeclocycline is categorized under the following by the FDA: Anti-bacterial Agents; Tetracyclines; ATC:D06AA01; ATC:J01AA01

Dosage Forms:
TABLET

Absorption:
Readily absorbed

Interactions:
[an error occurred while processing this directive]

Chemical IUPAC Name:
2-(amino-hydroxy-methylidene)-7-chloro-4-dimethylamino-6,10,11,12a-tetrahydroxy-4,4a,5,5a,6,12a-hexahydrotetracene-1,3,12-trione

Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.