Didanosine

This page contains recent news articles, when available, and an overview of Didanosine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Didanosine
(when available)

Pharmacology and use:
Didanosine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Didanosine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated. For treatment of Human immunovirus (HIV) infections

Mechanism Of Action:
Didanosine (ddI) is metabolized intracellularly by a series of cellular enzymes to its active moiety, 2,3–dideoxyadenosine-5-triphosphate (ddA-TP), which inhibits HIV DNA polymerase (reverse transcriptase). Didanosine inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA.

News Articles on Didanosine

SEXUALLY TRANSMITTED DISEASES:- THEIR NATURE AND CURE - THIRD PUBLICATION  -  ‎Dec 18, 2009‎
Examples of Anti-retroviral drugs are: Zidovudine (AZT or 31 Azido 31 deoxy thymidine) or retrovir, Nevirapine, Didanosine, Efavirenz, Lamivudine, ... Modern Ghana

Generic Name: efavirenz, emtricitabine, tenofovir  -  ‎Nov 11, 2009‎
...that happen when your immune system is weak (opportunistic infections).the amount of didanosine in your blood, which could result in more side effects. ... Pattaya Daily News

Five-year follow up of genotypic resistance patterns in HIV-1 subtype C ...  -  ‎Oct 25, 2009‎
Methods: At the beginning of the national program in 2002, almost all patients received stavudine (d4T), together with didanosine (ddI), as part of their ... 7thSpace Interactive (press release)

VIH et neuropathie périphérique  -  ‎Oct 20, 2009‎
Elles peuvent se voir lors des traitements par zalcitabine, didanosine ou stavudine. Il s'agit d'une neuropathie sensitive distale symétrique semblable à la ... Femmes et sida

La veinopathie portale oblitérante chez les patients infectés par le VIH  -  ‎Nov 10, 2009‎
à Madrid) et ont été reliés à la prise de didanosine. présence d'une hyperplasie nodulaire régénérative (HNR) [4] ou une dilatation sinusoïdale [5], ... Femmes et sida

HIV Drugs Linked to Increased Risk of Heart Attack  -  Apr 2, 2008
For those taking didanosine, the increased risk was about 50 percent. ... "If they have excellent control with abacavir or didanosine, then you look for ... Washington Post

Didanosine (Systemic).  -  Oct 27, 2005
Didanosine (di-DAN-oe-seen) (also known as ddI) is used in the treatment of the infection caused by the human immunodeficiency virus (HIV). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Abacavir, Didanosine Linked to Myocardial Infarction Risk  -  Apr 3, 2008
April 3, 2008 — Risk for myocardial infarction is increased in patients infected with HIV exposed to abacavir and didanosine within the preceding 6 months, ... Medscape

Didanosine (Systemic).(Drug overview)  -  May 1, 2006
Didanosine (di-DAN-oe-seen) (also known as ddI) is used in the treatment of the infection caused by the human immunodeficiency virus (HIV). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Aurobindo drug gets nod  -  Jul 13, 2006
Aurobindo Pharma Ltd has announced that the United States Food and Drug Administration (USFDA) has granted tentative approval for Didanosine tablets ... Hindu Business Line

Risk Of Heart Attack Increased With HIV Drugs, Abacavir And Didanosine...  -  Feb 8, 2008
A study to assess the adverse effects of anti-retroviral drugs shows that two widely-used HIV drugs are associated with an increased risk of heart attack ... Medical News Today - Medical News Today (press release)

Aurobindo receives US FDA Final approval for Didanosine Oral …  -  Mar 9, 2007
Aurobindo Pharma Ltd has announced that the US FDA has granted final approval for the Company's Didanosine Oral Suspension (Pediatric Powder) 10 mg / ml. ... Equity Bulls

INDIA'S AUROBINDO GRANTED APPROVAL TO MARKET DIDANOSINE …  -  Oct 11, 2006
MUMBAI, Oct 11 Asia Pulse - Aurobindo Pharma Ltd (BSE:524804) on Tuesday said it has received USFDA tentative approval for its Didanosine oral suspension ... Free with registration - AsiaPulse News - AccessMyLibrary.com

Didanosine Similar in Efficacy to Zidovudine in HAART Therapies With ...  -  Sep 21, 2007
By Ed Susman. CHICAGO, IL -- September 21, 2007 -- Didanosine-based treatment appears to be as successful as zidovudine in maintaining suppression of HIV in ... DG News

Aurobindo`s ARV gets USFDA nod  -  Jul 6, 2005
Stavudine is an antiviral agent of the nucleoside analog class which includes zidovudine (AZT), didanosine (ddl) and zalcitabine (ddC). ... Business Standard

AIDS drug prices to fall  -  Sep 24, 2006
As per initial estimates, RDPL would be able to make a 30-tablet/capsule pack of Didanosine 400 mg at Rs 1173, cheaper by over Rs 200 than Cipla's price. ... Times of India

Ritonavir Oral : Uses, Side Effects, Interactions, Pictures, Warnings...  -  Sep 30, 2008
When indinavir and didanosine are taken at the same time, ... If you take indinavir at the same time as your didanosine, the levels of indinavir in your ... WebMD

Abacavir, Didanosine Linked to Increased Heart Attack Risk  -  Feb 4, 2008
By Tim Horn. Abacavir—the active drug in Ziagen and a component of Epzicom and Trizivir—may double the risk of a heart attack in HIV-positive people ... AIDSmeds.com HIV/AIDS Treatment News

Aurobindo gets Bristol-Myers nod for 2 ARVs  -  Mar 18, 2006
Company (BMS) has given licence to market two important anti-retrovirals (ARVs) - Stavudine and Didanosine - in 49 countries, including South Africa. ... Hindu Business Line

Aurobindo Pharma gets USFDA nod for two drugs  -  Oct 10, 2008
Last month, the company had received two US FDA approval for manufacturing and marketing Didanosine Delayed Release capsules and Abacavir Sulfate tablets, ... The Hindu

Bristol Myers Squibb to cut price of two HIV drugs for children  -  Jun 28, 2005
The cost of stavudine will fall by 44% to 85 cents a day and didanosine by 90% to ... A generic formulation of didanosine was approved for use by the PEPFAR ... Aidsmap

AIDS drug prices to fall  -  Sep 25, 2006
As per initial estimates, RDPL would be able to make a 30-tablet/capsule pack of Didanosine 400 mg at Rs 1173, cheaper by over Rs 200 than Cipla's price. ... Pay-Per-View - Times of India - Factiva, from Dow Jones

HIV Drugs Abacavir, Didanosine Risky For Heart  -  Feb 9, 2008
According to a recent study, Abacavir and Didanosine, two widely used HIV drugs, have side effects like heart attack or formation of blood clots in the ... MedIndia

HIV/AIDS Therapy; Stavudine plus didanosine associated with decreased...  -  Mar 14, 2005
2005 MAR 14 - (NewsRx.com) -- Stavudine plus didanosine is associated with a decreased mitochondrial mass. According to a study from Spain, ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

HIV/AIDS Therapy; Stavudine plus didanosine associated with decreased...  -  Mar 19, 2005
2005 MAR 19 - (NewsRx.com) -- Stavudine plus didanosine is associated with a decreased mitochondrial mass. According to a study from Spain, ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

HIV/AIDS Therapy; Zidovudine and didanosine dosing in children has …  -  Mar 14, 2006
2006 MAR 14 - (NewsRx.com) -- Scientists have developed a simplified weight-based method for pediatric drug dosing for zidovudine and didanosine in ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

HIV/AIDS Therapy; Stavudine plus didanosine associated with decreased...  -  Mar 18, 2005
2005 MAR 18 - (NewsRx.com) -- Stavudine plus didanosine is associated with a decreased mitochondrial mass. According to a study from Spain, ... Pay-Per-View - Genomics & Genetics Weekly - Factiva, from Dow Jones

Reckoning the Risk: Abacavir, Didanosine and Heart Attacks in the...  -  Feb 26, 2008
...by David Evans and Tim Horn. It just wouldn't be the Conference on Retroviruses and Opportunistic Infections (CROI) without at least one element of surprise ... AIDSmeds.com HIV/AIDS Treatment News

HIV/AIDS Therapy; Stavudine plus didanosine associated with decreased...  -  Mar 16, 2005
2005 MAR 16 - (NewsRx.com) -- Stavudine plus didanosine is associated with a decreased mitochondrial mass. According to a study from Spain, ... Pay-Per-View - Immunotherapy Weekly - Factiva, from Dow Jones

Stavudine, didanosine and AZT pose diabetes risk in D:A:D study  -  Nov 20, 2006
A new analysis of D:A:D presented at the Eighth International Congress on Drug Therapy in HIV Infection in Glasgow last week looked at the risks associated ... Aidsmap

HIV/AIDS Therapy; Stavudine plus didanosine associated with decreased...  -  Mar 15, 2005
2005 MAR 15 - (NewsRx.com) -- Stavudine plus didanosine is associated with a decreased mitochondrial mass. According to a study from Spain, ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Study Data Link 2 NRTIs to Increased MI Risk  -  Mar 28, 2008
According to the FDA, separate studies of abacavir and didanosine conducted by ... Adverse events associated with use of abacavir or didanosine should be ... Medscape

HIV/AIDS Therapy; Stavudine plus didanosine associated with decreased...  -  Mar 14, 2005
2005 MAR 14 - (NewsRx.com) -- Stavudine plus didanosine is associated with a decreased mitochondrial mass. According to a study from Spain, ... Pay-Per-View - Hematology Week - Factiva, from Dow Jones

Amprenavir (Systemic).(Drug overview)  -  Aug 1, 2006
Antacids or Didanosine (eg, Videx) -- Use of antacids or didanosine with ... Antacids and didanosine should be taken at least one hour before or after ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Atazanavir-Based Regimen Has Greater Risk of Treatment Failure …  -  Aug 8, 2008
The efavirenz-based treatment was shown to be "conclusively" better than a more complicated regimen of didanosine, emtricitabine, and atazanavir (all taken ... DG News

Ubisol-Aqua(TM): Coenzyme Q10 May Prevent Toxicity of HIV Drug …  -  Jul 26, 2007
When cells were grown with stavudine or didanosine alone, ... After only 6 days, cells grown with didanosine alone were dying, but the cells grown with ... Free with registration - PR Newswire - AccessMyLibrary.com

HIV/AIDS Epidemiology; Reports add new data to HIV/AIDS epidemiology …  -  Oct 25, 2005
The genetic barriers to resistance to zidovudine, stavudine, lamivudine, and didanosine, for the above 3 regimens, were computed and analyzed. ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

HIV/AIDS Epidemiology; Reports add new data to HIV/AIDS epidemiology …  -  Oct 24, 2005
The genetic barriers to resistance to zidovudine, stavudine, lamivudine, and didanosine, for the above 3 regimens, were computed and analyzed. ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

HIV/AIDS Epidemiology; Reports add new data to HIV/AIDS epidemiology …  -  Oct 30, 2005
The genetic barriers to resistance to zidovudine, stavudine, lamivudine, and didanosine, for the above 3 regimens, were computed and analyzed. ... Pay-Per-View - Medical Letter on the CDC & FDA - Factiva, from Dow Jones

Arizona Administrative Code - R20-6-1205. Benefits; Prohibited...  -  Aug 12, 2005
...formerly Azidothymidine ("AZT"), Didanosine (ddI) and Zalcitabine (ddC), to the same extent as other prescription drugs and treatments. ... Pay-Per-View - Arizona Administrative Code - Loislaw

Poor Efficacy of Initial Therapy with d4T + ddI + EFV in Senegal:...  -  Oct 9, 2007
Comparison of twice-daily stavudine plus once- or twice-daily didanosine and ... A comparison of stavudine, didanosine and indinavir with zidovudine, ... Medscape

US FDA Issues Update of Ongoing HIV Drug Safety Review  -  Mar 27, 2008
These analyses showed that recent use of abacavir or didanosine was associated ... Bristol Myers Squibb (BMS), the manufacturer of didanosine, conducted an ... DG News

Zymes' CoQ10 reduces NRTI nerve damage.  -  Aug 6, 2007
After only six days, cells grown with didanosine alone were dying, but those also exposed to Ubisol-Aqua: Coenzyme Q10 as well as the NRTI grew and survived ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

ART Drug Interactions: Expert Interview w/ Dr. Corky Steinhart  -  Mar 4, 2005
Didanosine can be given with food if administered with tenofovir. However, very interestingly, over the last 6-9 months, some studies have suggested that in ... Medscape

La didanosine seule ou associée à la zidovudine est plus efficace que...  -  May 12, 2006
Englund JA, Baker CJ, Raskino C, et al., pour l'équipe des AIDS Clinical Trials Group (ACTG) Study 152. Zidovudine, didanosine, or both as the initial ... EBM Journal (Abonnement)

Africa: Daily HIV/Aids Report  -  Feb 6, 2008
Didanosine is a generic version of Bristol-Myers Squibb's VIDEX, which was FDA-approved in December 2004. The drug is used in combination with other ... AllAfrica.com

Zymes' CoQ10 reduces NRTI nerve damage.  -  Aug 1, 2007
After only six days, cells grown with didanosine alone were dying, but those also exposed to Ubisol-Aqua: Coenzyme Q10 as well as the NRTI grew and survived ... $4.95 - Nutraceuticals International - ECNext

Efficacy and Safety concerns regarding the co-administration of...  -  Mar 6, 2005
These have been observed in several clinical studies, 3-5, in which tenofovir disoproxil fumarate and didanosine were coadministered with a non-nucleoside ... i-newswire.com

Efficacy and Safety concerns regarding the co-administration of...  -  Mar 4, 2005
These have been observed in several clinical studies, 3-5, in which tenofovir disoproxil fumarate and didanosine were coadministered with a non-nucleoside ... Medical News Today - Medical News Today (press release)

Virostatics Doses First Patient in Phase IIa Trial of VS411 for the …  -  May 12, 2008
The combination of didanosine and hydroxyurea has been studied in many HIV-1 infected patients; however, these studies were performed with relatively high ... RedOrbit

Nucleoside Reverse Transcriptase Inhibitors, Myocardial Infarction in...  -  Dec 22, 2008
Patients receiving abacavir and not didanosine were compared with those receiving ... Didanosine was associated neither with altered risk of CVD nor with ... Medscape

Press Release: Ubisol-Aqua(TM): Coenzyme Q10 May Prevent Toxicity of …  -  Jul 26, 2007
When cells were grown with stavudine or didanosine alone, growth and survival was significantly impaired. However, when Ubisol-Aqua(TM): Coenzyme Q10 was ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Lactic acidosis in an HIV-infected patient receiving highly active …  -  Jun 15, 2005
Tenofovir might potentiate the effects of didanosine and/or its active metabolite, thereby increasing the risk or severity of didanosine toxicity, ... Nature.com

Abacavir (Ziagen) et didanosine associés à un risque accru d'infarctus...  -  Feb 7, 2008
Il est actuellement connu que le risque cardiovasculaire des patients traités infectés par le VIH est supérieur à celui des patients infectés non traités et ... Femmes et sida

University of Amsterdam, Netherlands; Journal articles present study ...  -  Dec 5, 2006
Study 2: Investigators compare two once-daily regimens with a regimen consisting of nelfinavir, didanosine, and stavudine in antiretroviral therapy-naive ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

'Dear Dr' letter issued about risks of using tenofovir and ddI...  -  Mar 4, 2005
The drug companies therefore warn “co-administration of didanosine and tenofovir ... Early virologic failure with a combination of tenofovir, didanosine and ... Aidsmap

Accueil / Actualités / Sciences / 0807030143 : L'Ubisol-Aqua(TM): …  -  Aug 3, 2007
Deux des INTI encore en usage clinique (la stavudine et la didanosine) peuvent endommager les tissus nerveux (neuropathie). La neuropathie est l'un des ... Intelink

USPHS releases updated guidelines for management of occupational …  -  Dec 1, 2005
Lamivudine plus didanosine Diarrhea more common with buffered preparation; ... Emtricitabine plus didanosine Emtricitabine: see above Didanosine: see above ... $4.95 - American Family Physician - ECNext

… d'infarctus du myocarde sous abacavir ou didanosine : l'Afssaps se...  -  Apr 8, 2008
Cette étude suggère que la prise d'abacavir ou de didanosine, ... De plus, les données des essais cliniques menés avec la didanosine sont limitées et ne ... Femmes et sida

Videx y Videx EC (didanosine, ddI)  -  Mar 1, 2008
Videx y Videx EC son medicamentos anti-VIH, que pertenecen a la categoría de los inhibidores nucleósidos de la transcriptasa reversa (INTR). ... AIDSmeds.com HIV/AIDS Treatment News

Long-term complete remission of laryngeal Kaposi's sarcoma after …  -  Mar 24, 2005
Management Highly active antiretroviral treatment (stavudine, didanosine, and nelfinavir), tracheotomy, and palliative radiotherapy. ... Nature.com

Article: Videx.(PRODUCT REVIEW: SECURITY PRODUCTS) - American …  -  Jun 1, 2008
Results from a 48-week study demonstrate that VIDEX EC (didanosine) ... Study results indicate switching from Videx(R) (didanosine) chewable tablets to ... Pay-Per-View - American Coin-Op - HighBeam Research

Adverse Drug Reaction; Drugs raise mitochondrial toxicity risk in...  -  Oct 28, 2005
..."Coadministration of ribavirin with didanosine should be avoided. ... Didanosine should be suspended if clinical signs or symptoms of mitochondrial toxicity ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

St. Antoine Hospital, Paris; Drugs raise mitochondrial toxicity risk...  -  Oct 26, 2005
..."Coadministration of ribavirin with didanosine should be avoided. ... Didanosine should be suspended if clinical signs or symptoms of mitochondrial toxicity ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Adverse Drug Reaction; Drugs raise mitochondrial toxicity risk in...  -  Oct 25, 2005
..."Coadministration of ribavirin with didanosine should be avoided. ... Didanosine should be suspended if clinical signs or symptoms of mitochondrial toxicity ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Adverse Drug Reaction; Drugs raise mitochondrial toxicity risk in...  -  Oct 27, 2005
..."Coadministration of ribavirin with didanosine should be avoided. ... Didanosine should be suspended if clinical signs or symptoms of mitochondrial toxicity ... Pay-Per-View - Blood Weekly - Factiva, from Dow Jones

New paradigms in the management of hepatitis C virus co-infections  -  Jul 31, 2006
Another interaction of interest is that between ribavirin and didanosine. Ribavirin prevents the metabolism of didanosine, a drug that is associated with ... Nature.com

Second Phase III Study Evaluating Gilead's Viread(R) for the Treatment...  -  Jun 25, 2007
Coadministration of Viread and didanosine should be undertaken with caution. Patients should be monitored closely for didanosine-associated adverse events, ... Free with registration - Business Wire - AccessMyLibrary.com

Has HAART failed?(Highly active antiretroviral therapy)  -  May 16, 2005
Tenofovir will increase didanosine concentration and toxicity risk. Didanosine dose should be decreased to 250 mg when given with tenofovir. ... Free with registration - Drug Topics - AccessMyLibrary.com

AIDS Patients on Tenofovir Must Be Monitored For Renal Failure Caused...  -  Nov 14, 2005
In addition, the researchers reported that didanosine clearance is much greater than GFR, ... Tenofovir increases didanosine blood levels by 28%, ... DG News

Un médicament anti-sida augmente le risque de crise cardiaque  -  Apr 3, 2008
Il s'agit de la didanosine portant le nom de Videx. Les experts s'entendent pour dire que les médecins doivent être conscients des risques de crises ... Taxiclic

Antifungals, Azole (Systemic).(Drug overview)  -  May 1, 2006
Itraconazole and ketoconazole should be taken at least 2 hours before or 2 hours after didanosine is given Digoxin (eg, Lanoxin) -- Digoxin concentrations ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

L'Ubisol-Aqua(TM): Coenzyme Q10 pourrait prévenir la toxicité des …  -  Jul 26, 2007
Deux des INTI encore en usage clinique (la stavudine et la didanosine) peuvent endommager les tissus nerveux (neuropathie). La neuropathie est l'un des ... ITNews

Adverse Effects of Antiretrovirals in HIV-Infected Pregnant Women : …  -  Feb 28, 2006
One woman who experienced severe elevations of both lipase and bilirubin was able to continue her initial ARV regimen of didanosine, lamivudine, ... Medscape

Antiadrenal Ketoconazole Antifungal, systemic Fluconazole Itraconazole...  -  Aug 1, 2006
Itraconazole and ketoconazole should be taken at least 2 hours before or 2 hours after didanosine is given Digoxin (eg, Lanoxin) -- Digoxin concentrations ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Netherlands Corporate News - De evaluerende fase III studie van...  -  Jul 6, 2007
Coadministration of Viread and didanosine should be undertaken with caution. Patients should be monitored closely for didanosine-associated adverse events, ... Netherlands Corporate News - Netherlands Corporate News (persbericht)

Article: Videx Inc.(SECURITY PRODUCTS) - Automatic Merchandiser | …  -  Jan 1, 2006
Advisory Committee unanimously recommended that VIDEX(R) (didanosine; ... Results from a 48-week study demonstrate that VIDEX EC (didanosine) capsules had ... Pay-Per-View - Automatic Merchandiser - HighBeam Research

Link between diabetes and antiretrovirals may particularly affect...  -  Jun 18, 2007
In a separate analysis, current treatments associated with the greatest risk of diabetes were indinavir, lamivudine-stavudine, didanosine-stavudine, ... Aidsmap

HIV/AIDS Therapy; CD4+ decline identified in patients with complete...  -  Jul 11, 2005
According to a study from Spain, "Tenofovir (TDF) and didanosine (ddl) are both adenosine analogues with convenient posology, strong potency and a ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

HIV/AIDS HAART; Initial therapy has diminished efficacy in patients...  -  Dec 19, 2005
2005 DEC 19 - (NewsRx.com) -- Initial therapy with didanosine, tenofovir, ... Keywords: London, England, HIV/AIDS, Didanosine, Efavirenz, Tenofovir, ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

Article: Two nucleoside analogues increase MI risk in HIV.(Infectious...  -  Mar 15, 2008
...find Internal Medicine News articles. BOSTON -- Recent use of the nucleoside analogues abacavir and didanosine is associated with a significantly i... Pay-Per-View - Internal Medicine News - HighBeam Research

First-Time Generic Approvals: Celexa, Videx, Dermatop  -  Mar 16, 2007
Didanosine, a nucleoside analog, is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection. ... Medscape

Netherlands Corporate News - Gilead dient marktapplicaties in bij …  -  Dec 10, 2007
The US package insert advises that co-administration of Viread and didanosine should be undertaken with caution. Patients should be monitored closely for ... Netherlands Corporate News - Netherlands Corporate News (persbericht)

Netherlands Corporate News - Europees CHMP geeft positief advies …  -  Mar 20, 2008
The US package insert advises that co-administration of Viread and didanosine should be undertaken with caution. Patients should be monitored closely for ... Netherlands Corporate News - Netherlands Corporate News (persbericht)

Inhoud van deze bijsluiter  -  Mar 11, 2005
Didanosine valt in de geneesmiddelengroep van de nucleoside reverse ... Didanosine geneest de infectie niet en patienten kunnen ziekten die gecombineerd met ... Consumed

Brochure Bijwerkingen - St Middelen  -  Jun 10, 2005
Tijdens het geneesmiddelenonderzoek met didanosine en zalcitabine kwam reeds naar ... Met de toename van het gebruik van vooral didanosine is steeds meer ... Hiv Vereniging Nederland

Résultats de l'étude DAD sur le risque potentiel d'infarctus du...  -  Apr 3, 2008
L'abacavir et la didanosine (inhibiteurs nucléosidiques de la transcriptase ... La didanosine est disponible sous le nom de Videx® ( Bristol-Myers Squibb) . ... Caducée.net

ê°?염관련 종합학술대회  -  Mar 16, 2006
Didanosine� 위산�서 화학�으로 불안정하므로 didanosine tablet�는 calcium carbonate와 ... 따�서 didanosine tablet과 fluoroquinolone� 함께 투여하면 ... 메디칼트리뷴

Age-dependent Pharmacokinetics of Lamivudine in HIV-infected Children  -  Oct 15, 2006
A randomized study of combined zidovudine-lamivudine versus didanosine monotherapy in children with symptomatic therapy-naive HIV-1 infection. ... Nature.com

Barr Reports First Quarter Fiscal 2006 Earnings of $0.78 Per Share  -  Jan 11, 2005
..."Strong generic products sales, principally sales of our Desmopressin and Didanosine products, and $44 million of alliance, development and other revenue ... Euro am Sonntag

PHASE IIB STUDY SHOWS REVERSET ACHIEVES ANTIVIRIRAL …  -  Sep 1, 2005
Didanosine labeling states that the dose of ddI should be reduced when ... Importantly, in patients who were not also receiving didanosine (ddI), ... Entrepreneur

Amprenavir (Systemic).  -  Jul 28, 2005
Antacids and didanosine should be taken at least one hour before or after amprenavir. Bepridil (eg Vascor) -- Use of bepridil and amprenavir together can ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

A Review of the Aetiology of Dyslipidaemia and Hyperlipidaemia in …  -  Oct 29, 2005
...although the decline was more rapid in the group who received stavudine/didanosine relative to the group who received zidovudine/lamivudine (Figure 1). ... RedOrbit

Antiretroviral Drug Resistance and Routine Therapy, Cameroon  -  Jun 13, 2006
Two patients (1.6%) initially received only 2 NRTIs (lamivudine and zidovudine for 7 months in 1 case; stavudine and didanosine for 14 months in the other). ... Medscape

Tenofovir may linger up to 3 weeks in body: discontinue with caution  -  Jun 14, 2005
Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency ... Aidsmap

GI Journal Scan Dec 2004  -  Jan 18, 2005
Eleven cases of pancreatitis or symptomatic hyperlactatemia were observed, all in patients receiving didanosine-containing antiretroviral regimens. ... Medscape

Progress in Treating HIV Infection: State-of-the Art Issues and...  -  Aug 31, 2005
In the Atlantic Study, only 28% of the patients in the lamivudine/ stavudine/didanosine arm achieved an HIV RNA < 50 copies/mL at 96 weeks, ... Medscape

European Commission Approves Viread For Chronic Hepatitis B  -  Apr 28, 2008
The US package insert advises that co-administration of Viread and didanosine should be undertaken with caution. Patients should be monitored closely for ... Medical News Today - Medical News Today (press release)

Un m&eacute;dicament anti-SIDA r&eacute;pandu augmente le risque de …  -  Apr 2, 2008
L'abacavir et la didanosine sont actuellement recommandés par l'OMS pour les personnes séropositives. "Dans les pays développés, les médecins peuvent ... nouvelobs.com

Bloomberg Printer-Friendly Page  -  Dec 11, 2007
Coadministration of ATRIPLA with didanosine should be undertaken with caution. Patients receiving this combination should be monitored closely for ... Bloomberg

Au coeur de DAD  -  May 31, 2008
L'autre antirétroviral incriminé dans une moindre mesure est la didanosine (ddI) commercialisée par Bristol-Myers-Squibb sous le nom de Videx®. ... Act Up-Paris

Nouvelles recommandations européennes concernant l'administration …  -  Mar 3, 2005
Les spécialités Videx® (didanosine) et Viread® (ténofovir DF) ont été autorisées dans ... L'administration concomitante de Videx® (didanosine) et de Viread® ... InformationHospitaliere.com

HIV/AIDS Therapy; NRTIs cross the placenta by simple diffusion and …  -  Feb 8, 2005
..."A significant relationship between concentrations in maternal and cord plasma samples was found for zidovudine, lamivudine, stavudine, and didanosine. ... Pay-Per-View - Virus Weekly - Factiva, from Dow Jones

Incyte's HIV Drug Shows Promise  -  Jul 26, 2005
The cases of pancreatitis occurred in patients receiving the 100 mg dose, in combination with didanosine and another drug called tenofovir. ... Subscription - Wall Street Journal Online - Dow Jones & Company

HIV/AIDS Therapy; NRTIs cross the placenta by simple diffusion and …  -  Feb 10, 2005
..."A significant relationship between concentrations in maternal and cord plasma samples was found for zidovudine, lamivudine, stavudine, and didanosine. ... Pay-Per-View - Women's Health Weekly - Factiva, from Dow Jones

Brand Names/Synonyms:
Didanosine is also known by the following brand names and/or synonyms2'3'-DIDEOXYINOSINE; 2DI; CCRIS 805; DDI; DIDEOXYINOSINE; Ddi; Ddi, Didanosine; Didanosine; Didanosine [Usan:Ban:Inn]; Dideoxyinosine; Videx; Videx Ec; [Inn-Latin]; [Inn-Spanish]

Drug Category:
Didanosine is categorized under the following by the FDA: Anti-HIV Agents; Antimetabolites; Nucleoside and Nucleotide Reverse Transcriptase Inhibitors; ATC:J05AF02

Dosage Forms:
CAPSULE (ENTERIC-COATED); POWDER FOR SOLUTION; TABLET

Absorption:
Rapidly absorbed (bioavailability = 30-40%) with peak plasma concentrations appearing within 0.5 and 1.5 hrs.

Interactions:
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Chemical IUPAC Name:
9-[5-(hydroxymethyl)tetrahydrofuran-2-yl]-3,9-dihydropurin-6-one





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