Dihydroergotamine

This page contains recent news articles, when available, and an overview of Dihydroergotamine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Dihydroergotamine
(when available)

Pharmacology and use:
Dihydroergotamine is indicated for the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes. Dihydroergotamine binds with high affinity to 5-HT1Da and 5-HT1Db receptors. It also binds with high affinity to serotonin 5-HT1A, 5-HT2A, and 5-HT2C receptors, noradrenaline a2A, a2B and a receptors, and dopamine D2L and D3 receptors. The therapeutic activity of Dihydroergotamine in migraine is generally attributed to the agonist effect at 5-HT1D receptors. For the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes.

Mechanism Of Action:
Two theories have been proposed to explain the efficacy of 5-HT1D receptor agonists in migraine: 1) activation of 5-HT1D receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, leads to vasoconstriction, which correlates with the relief of migraine headache and 2) activation of 5-HT1D receptors on sensory nerve endings of the trigeminal system results in the inhibition of pro-inflammatory neuropeptide release.

News Articles on Dihydroergotamine

Migraine Inhaler  -  ‎Dec 31, 2009‎
Researchers are now testing a new form of a migraine medication, called Levadexâ„¢ (dihydroergotamine). Normally, the drug is given in the form of an ... WSOCtv.com

Pharmacological Options in the Management of Orthostatic Hypotension in Older ...  -  ‎Dec 11, 2009‎
Thulesius O, Giores JE, Berlin E. Vasoconstrictor effects of midodrine, ST 1059, noradrenaline, etilifrine and dihydroergotamine on isolated human veins Eur ... Medscape

MAP Pharmaceuticals Secures $60 Million Committed Equity Financing Facility  -  ‎Nov 12, 2009‎
It is a novel formulation of dihydroergotamine (DHE), a drug used intravenously in clinical settings to effectively and safely treat migraines. ... CNNMoney.com (press release)

MAP PHARMACEUTICALS, INC. (MAPP) CFO Christopher Y Chai sells 10000 Shares  -  ‎Nov 4, 2009‎
...for the potential treatment of children with asthma and a proprietary formulation of inhaled dihydroergotamine for the potential treatment of migraine. ... GuruFocus.com

MAP Pharmaceuticals Completes Interim Safety Review of LEVADEX(TM) Open-Label ...  -  ‎Oct 29, 2009‎
It is a novel formulation of dihydroergotamine (DHE), a drug used intravenously in clinical settings to effectively and safely treat migraines. ... Reuters

FDA Approves Labeling Update for REYATAZ® (atazanavir sulfate) Capsules to ...  -  ‎Nov 5, 2009‎
These and other contraindicated drugs are: rifampin, irinotecan, orally administered midazolam, triazolam, dihydroergotamine, ergotamine, ergonovine, ... WELT ONLINE

Dihydroergotamine (Nasal-Systemic).(Drug overview)  -  May 1, 2006
Dihydroergotamine ( dye-hye-droe-er-GOT-a-meen) belongs to the group of medicines called ergot alkaloids. It is a nasal solution used to help relieve ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Cluster Headache Managing Cluster Headaches - Cluster Headache …  -  Sep 9, 2008
Other drugs that may be used for acute attacks are nasal sprays of dihydroergotamine or lidocaine. Cluster headache attacks are usually short, lasting from ... New York Times

DIHYDROERGOTAMINE (Nasal route) - dye-hye-droe-er-GOT-a-meen.( …  -  May 1, 2007
Serious and/or life-threatening peripheral ischemia has been associated with the coadministration of dihydroergotamine with potent CYP3A4 inhibitors ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

MAP Pharmaceuticals Reports Positive Phase 2 Results For Its Inhaled ...  -  Mar 2, 2007
The candidate is a proprietary orally inhaled formulation of dihydroergotamine (DHE) for the treatment of acute migraine. ... Medical News Today - Medical News Today (press release)

Valeant Pharmaceuticals Introduces Redesigned Migranal Delivery …  -  Jun 27, 2005
Dihydroergotamine is effective for use any time during a migraine and is an ... The study investigated the effects of dihydroergotamine in a rat model of ... RedOrbit

Headache Medicines, Ergot Derivative-Containing ( Systemic).  -  Oct 27, 2005
Dihydroergotamine and ergotamine belong to the group of medicines known as ergot ... Dihydroergotamine and ergotamine are not ordinary pain relievers. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

MAP Pharmaceuticals Announces Pricing of Its Initial Public Offering.  -  Oct 5, 2007
...for the potential treatment of children with asthma, and a proprietary formulation of inhaled dihydroergotamine for the potential treatment of migraine. ... Free with registration - PR Newswire - AccessMyLibrary.com

HEADACHE MEDICINE ERGOT-DERIVATIVE-CONTAINING (Oral route, …  -  May 1, 2007
Dihydroergotamine and ergotamine belong to the group of medicines known as ergot ... Dihydroergotamine and ergotamine are not ordinary pain relievers. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Press Release: MAP Pharmaceuticals to Present MAP0004 Phase 2 …  -  Jun 5, 2007
Dihydroergotamine Mesylate, Injection Patient Medication Advisory This medicine is ... The Mosby Medical Encyclopedia 10-01-1996 dihydroergotamine mesylate, ... Pay-Per-View - PR Newswire - HighBeam Research

MAP Pharmaceuticals to Present MAP0004 Phase 2 Clinical Data at the …  -  Jun 5, 2007
The poster presentation, which was accepted as a late-breaker, is entitled Rapid and Sustained Clinical Efficacy and Safety of Inhaled Dihydroergotamine ... Genetic Engineering News - Genetic Engineering News (press release)

MAP Pharmaceuticals To Present MAP0004 Phase 2 Clinical Data At The …  -  Jun 6, 2007
Clinical Safety of Inhaled Dihydroergotamine Mesylate via a Novel System (Tempo(TM) Inhaler); Poster ID F07; June 8, 12:30 to 1:30pm CDT. ... Medical News Today - Medical News Today (press release)

Inhaled migraine drug VR147 shows early promise  -  Apr 16, 2008
For such individuals the drug dihydroergotamine is often employed as an alternative. However, while dihydroergotamine overcomes some of the problems ... In-PharmaTechnologist.com

Analysis: Botox for Headaches?  -  May 6, 2006
Five attacks required two dosages of dihydroergotamine spray; ... We conclude that the long half-life of dihydroergotamine used in a nasal- spray ... RedOrbit

Variety of drug regimens used to treat painful migraine headaches:...  -  Jan 1, 2005
..."A triptan or dihydroergotamine is the drug of choice for treatment of ... Ergot alkaloids such as dihydroergotamine constrict blood vessels and have been ... Free with registration - Managed Healthcare Executive - AccessMyLibrary.com

APS: For Migraine and Cluster Headaches, Most Anything Is Worth a Try  -  May 15, 2006
Five attacks required two dosages of dihydroergotamine spray; ... "We conclude that the long half-life of dihydroergotamine used in a nasal spray ... MedPage Today

What are effective medical treatments for adults with acute migraine?(...  -  Jun 1, 2006
A systematic review (7) revealed that dihydroergotamine (DHE) alone was less ... Parenteral dihydroergotamine for acute migraine headache: a systematic ... $4.95 - Journal of Family Practice - ECNext

Rebound headaches  -  Dec 8, 2007
Interestingly, the ergot dihydroergotamine appears to have a lower ... Dihydroergotamine (DHE), an injectable ergot, helps relieve rebound headache pain ... CNN

An Update on Chronic Pain Treatments  -  Oct 14, 2008
Dihydroergotamine (DHE) injections and dihydroergotamine and caffeine nasal spray are also options. Antiemetics include ondansetron and promethazine. ... Medscape

Valeant Pharmaceuticals to Partner with ASCEND Therapeutics to …  -  Oct 1, 2007
Because CYP3A4 inhibition elevates the serum levels of dihydroergotamine, the risk for vasospasm leading to cerebral ischemia and/or ischemia of the ... $4.95 - Business Wire - ECNext

Metoclopramide for Pain and Nausea in Patients with Migraine  -  May 1, 2005
The combination of metoclopramide and dihydroergotamine was more effective than dihydroergotamine alone, valproate, meperidine/hydroxyzine, ketorolac, ... AAFP News Now

MAP Pharmaceuticals Reports Positive Pharmacological Response Data …  -  Jun 29, 2008
MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) presented data from an in-vitro study evaluating receptor pharmacology of MAP0004, orally inhaled dihydroergotamine ... Medical News Today - Medical News Today (press release)

Mayo Clinic expertise  -  Feb 19, 2008
Dihydroergotamine, an ergot derivative, is more effective and has fewer side effects than ergotamine. It's available as an injection or nasal spray. ... MayoClinic.com

Article: Intradermal botulinum eases cervical migraine.(Drug overview)...  -  Jul 15, 2006
Dihydroergotamine Nasal Spray (Migranal NS) For Pre-Emption of Menstrual/Early Morning Migraines" - Presented by John Claude Krusz, Ph.D., M.D. from Anodyne ... Pay-Per-View - Family Practice News - HighBeam Research

Press Release: MAP Pharmaceuticals Reports Positive Pharmacological …  -  Jun 28, 2008
PR Newswire; June 24, 1993 ; 700+ words ... ... acute migraine following administration of DHE-45(R) (dihydroergotamine mesylate ... Pharmaceuticals Corp. ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: MAP Pharmaceuticals Reports Positive Results From …  -  Mar 24, 2008
...proprietary version of nebulized budesonide for the potential treatment ... dihydroergotamine delivered by MAP Pharmaceuticals' Tempo(TM) inhaler ... ... Pay-Per-View - PR Newswire - HighBeam Research

MAP Pharmaceuticals Reports Positive Phase 2 Results for its Inhaled ...  -  Mar 1, 2007
The candidate is a proprietary orally inhaled formulation of dihydroergotamine (DHE) for the treatment of acute migraine. ... Free with registration - PR Newswire - AccessMyLibrary.com

MAP Pharmaceuticals Closes $50 Million Financing.  -  Mar 27, 2007
Tempo(TM) Migraine: Tempo Migraine is an inhaled formulation of dihydroergotamine (DHE) in the Company's proprietary Tempo(TM) Inhaler platform, ... $4.95 - PR Newswire - ECNext

Inhaled insulin flops, but field may hold promise  -  Apr 13, 2008
The active ingredient in MAP's migraine drug, known as MAP0004, is dihydroergotamine, which has been used intravenously for 60 years by hospitals for ... Reuters

Treatment for Acute Attacks  -  Sep 9, 2008
Injections of the ergotamine-derived drug known as dihydroergotamine (DHE) can stop cluster attacks within 5 minutes in many patients, offering benefits ... New York Times

Abbott Statement on Agreement With Brazilian Government for Kaletra(R)...  -  Jul 11, 2005
Kaletra should not be taken with astemizole, cisapride, dihydroergotamine, ergonovine, ergotamine, methylergonovine, midazolam, pimozide, terfenadine or ... Medical News Today - Medical News Today (press release)

Migraine Treatment Approaches - Migraine Health Information - NY...  -  Sep 9, 2008
Examples of drugs that may be used include dihydroergotamine (with or without metoclopramide), NSAIDs (in mild cases), corticosteroids, or valproate. ... New York Times

Milwaukee Journal Sentinel : DRUG CAPSULE WHAT YOU SHOULD …  -  Jul 4, 2005
It also should not be used with pimozide, weight loss drugs, tryptophan, terfenadine, astemizole, dihydroergotamine. More info: www.zoloft.com; ... $2.95 - Milwaukee Journal Sentinel - NewsBank

Headache - Symptoms, Causes, Tests - NY Times Health Information  -  Jun 19, 2008
Prescription medications used for migraine headaches include ergotamine, dihydroergotamine, ergotamine with caffeine (Cafergot), isometheptene (Midrin), ... New York Times

PREZISTA Receives US FDA Approval as Part of HIV Combination …  -  Jun 23, 2006
PREZISTA/rtv is contraindicated with astemizole, terfenadine, dihydroergotamine, ergonovine, ergotamine, methylergonovine, cisapride, pimozide, midazolam, ... Free with registration - PR Newswire - AccessMyLibrary.com

The Family Doctor / - Keep a diary of headaches  -  Nov 22, 2005
...including medicines injected under the skin (sumatriptan and dihydroergotamine), aerosols (ergotamine and butorphanol), and even 100 percent oxygen. ... $2.95 - Buffalo News - NewsBank

Migraine with skin sensitivity eased by older drug  -  Jul 2, 2007
NEW YORK (Reuters Health) - Dihydroergotamine or DHE, an established drug for migraine, works well even when the attack is accompanied by super-sensitivity ... Reuters UK

DRUG CAPSULE WHAT YOU SHOULD KNOW | Article from The …  -  Jul 4, 2005
It also should not be used with pimozide, weight loss drugs, tryptophan, terfenadine, astemizole, dihydroergotamine. More info: www.zoloft.com; ... Pay-Per-View - Milwaukee Journal Sentinel - HighBeam Research

Abbott在å?—é?žæ??出抗HIVæ–°è?¯ç‰‡å‰‚注册申请  -  Apr 5, 2006
Lopinavir/ritonavir�应与astemizole�cisapride�dihydroergotamine�ergonovine �ergotamine�methylergonovine�midazolam�pimozide�terfenadine或triazolam一� ... ��

Abbott's New Tablet Formulation of Kaletra(R) (lopinavir/ritonavir) …  -  Jul 3, 2006
Kaletra should not be taken with amiodarone, astemizole, cisapride, dihydroergotamine, ergonovine, ergotamine, methylergonovine, midazolam, pimozide, ... Free with registration - PR Newswire - AccessMyLibrary.com

New Abbott Aluvia® Tablet for Treatment of HIV Available in South...  -  Jun 2, 2008
Do not take Aluvia with astemizole, terfenadine, midazolam, triazolam, pimozide, cisapride, ergotamine, dihydroergotamine, ergonovine, methylergonovine, ... AllAfrica.com

Valeant Buying Out Xcel's Neurology Line For $280M  -  Feb 4, 2005
Also in the Xcel hopper are Diastat (diazepam) for acute repetitive epileptic seizures outside of a hospital setting, and Migranal (dihydroergotamine), ... BioWorld Online - BioWorld Online

Tibotec Therapeutics Announces Initiation of the Largest US Clinical ...  -  Sep 28, 2006
...terfenadine, dihydroergotamine, ergonovine, ergotamine, methylergonovine, cisapride, pimozide, midazolam, or triazolam) and for which elevated plasma ... Free with registration - PR Newswire - AccessMyLibrary.com

Some facts about migraines  -  Feb 6, 2007
Dihydroergotamine (DHE) may be used for self-injection. DHE is also available as the nasal spray Migranal. A combination product containing isometheptene ... Pittsburgh Post-Gazette - Pittsburgh Post Gazette

Ergotamines for cluster headaches  -  Apr 11, 2008
Dihydroergotamine mesylate, which is generally given as a shot (DHE), is also available as a nasal spray (Migranal). DHE can also be given through a vein ... WebMD

Abbott's New Tablet Formulation Of Kaletra(R) (Lopinavir/Ritonavir) …  -  Apr 30, 2006
Kaletra should not be taken with astemizole, cisapride, dihydroergotamine, ergonovine, ergotamine, methylergonovine, midazolam, pimozide, terfenadine or ... Medical News Today - Medical News Today (press release)

Abbott Statement on Agreement With Brazilian Government for Kaletra(R)...  -  Jul 12, 2005
Kaletra should not be taken with astemizole, cisapride, dihydroergotamine, ergonovine, ergotamine, methylergonovine, midazolam, pimozide, terfenadine or ... i-newswire.com

Analysis Provides Additional Data For PREZISTA As Part Of HIV …  -  Aug 15, 2006
PREZISTA/rtv is contraindicated with astemizole, terfenadine, dihydroergotamine, ergonovine, ergotamine, methylergonovine, cisapride, pimozide, midazolam, ... Medical News Today - Medical News Today (press release)

Abbott Agrees With World Health Organization (WHO) Director-General...  -  Apr 10, 2007
...ergotamine, dihydroergotamine, ergonovine and methylergonovine), products containing St. John's wort (Hypericum perforatum) and vardenafil. ... Free with registration - PR Newswire - AccessMyLibrary.com

New Data Show a Kaletra(R) (Lopinavir/Ritonavir)-Based Regimen …  -  Nov 18, 2005
Kaletra should not be taken with astemizole, cisapride, dihydroergotamine, ergonovine, ergotamine, methylergonovine, midazolam, pimozide, terfenadine or ... biotech-intelligence.com

A press release distributed by PR Newswire Europe  -  Apr 4, 2006
Lopinavir/ritonavir should not be taken with astemizole, cisapride, dihydroergotamine, ergonovine, ergotamine, methylergonovine, midazolam, pimozide, ... prnewswire.co.uk

Drug-specific migraine treatment: with few exceptions, most types of ...  -  Feb 1, 2005
Dihydroergotamine given parenterally or by nasal spray is another option. Opioids are useful if triptans are not an option. ... Free with registration - Patient Care for the Nurse Practitioner - AccessMyLibrary.com

MAP Pharmaceuticals Initiates Phase 2 Clinical Trial in Patients With...  -  Sep 5, 2006
MAP0004 is a novel inhaled drug formulation of dihydroergotamine mesylate (DHE) administered with MAP's patented Tempo(TM) Inhaler. ... Free with registration - PR Newswire - AccessMyLibrary.com

• Migraine Headaches: How to Deal with the Pain  -  Nov 1, 2005
Dihydroergotamine (brand names: Migranal, DHE 45) is like ergotamine and also can help. Other prescription medicines for migraines include sumatriptan ... AAFP News Now

MAP Pharmaceuticals Initiates Phase 3 Clinical Trial of Unit Dose …  -  Jan 7, 2008
...and a proprietary version of orally inhaled dihydroergotamine delivered by MAP Pharmaceuticals' proprietary Tempo(TM) inhaler for the potential ... Free with registration - PR Newswire - AccessMyLibrary.com

Nicole Kidman Terima "Order of Australia"  -  Apr 10, 2007
...ergotamine, dihydroergotamine, ergonovine dan methylergonovine) produk yang berisikan “wort St John� (Hypericum perforatum) dan vardenafil. ... ANTARA

Welcome to News-Journal!  -  May 16, 2006
Prescription medications used for migraine headaches include ergotamine, dihydroergotamine, ergotamine with caffeine (Cafergot), isometheptene (Midrin), ... News-Journal.com

Variety of drugs available for cluster headache prophylaxis.(Neurology...  -  Mar 1, 2005
Dihydroergotamine can be given by daily intramuscular injections for 1-2 weeks, or by an intravenous infusion for 3 days, he said. ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Abbott Submits EU and US Regulatory Filings for New Lower-Strength …  -  Jul 20, 2007
Do not take Kaletra with astemizole, terfenadine, midazolam, triazolam, pimozide, cisapride, ergotamine, dihydroergotamine, ergonovine, and methylergonovine ... Free with registration - PR Newswire - AccessMyLibrary.com

MAP Pharmaceuticals Announces Resignation of Chief Medical Officer.  -  Feb 5, 2008
...a proprietary version of orally inhaled dihydroergotamine delivered by MAP Pharmaceuticals' Tempo(TM) inhaler for the potential treatment of migraine. ... Free with registration - PR Newswire - AccessMyLibrary.com

Boehringer Ingelheim Initiates SPRING Study of Aptivus(R) (tipranavir)...  -  Jun 14, 2007
APTIVUS/ritonavir is contraindicated with amiodarone, bepridil, flecainide, propafenone, quinidine, astemizole, terfenadine, dihydroergotamine, ergonovine, ... Free with registration - PR Newswire - AccessMyLibrary.com

Management of cluster headache.  -  Feb 15, 2005
Intranasal dihydroergotamine can reduce attack severity, but it does not reduce attack frequency or duration. This nasal spray has fewer adverse reactions ... Free with registration - American Family Physician - AccessMyLibrary.com

Building Better Algorithms for the Diagnosis of Nontraumatic Headache  -  Dec 1, 2006
...ketorolac) along with treatment for nausea, as opposed to using an antinausea and a migraine-specific medication (eg, a triptan or dihydroergotamine), ... Psychiatric Times

MAP Pharmaceuticals to Present at the Cowen & Company 27th Annual …  -  Mar 9, 2007
...the potential treatment of children with asthma, and a proprietary formulation of inhaled dihydroergotamine for the potential treatment of migraines. ... Genetic Engineering News - Genetic Engineering News (press release)

MAP Pharmaceuticals to Present at the CIBC World Markets Annual …  -  Apr 10, 2007
...for the potential treatment of children with asthma, and a proprietary formulation of inhaled dihydroergotamine for the potential treatment of migraine. ... Free with registration - PR Newswire - AccessMyLibrary.com

MAP Pharmaceuticals to Present at Upcoming Investor Conferences.  -  Nov 27, 2007
...and a proprietary formulation of inhaled dihydroergotamine for the potential treatment of migraine, as well as a proprietary combination of an inhaled ... Free with registration - PR Newswire - AccessMyLibrary.com

Second Inhaled Insulin Down; Firms, Analysts Keeping Faith  -  Jan 21, 2008
MAP0004, an inhaled version of dihydroergotamine, aims at providing quicker and more convenient pain relief over the oral triptans or intravenous DHE in ... BioWorld Online - BioWorld Online

Supplemental New Drug Application For PREZISTAâ„¢ Submitted To US …  -  Dec 25, 2007
...terfenadine, dihydroergotamine, ergonovine, ergotamine, methylergonovine, cisapride, pimozide, midazolam, or triazolam) and for which elevated plasma ... Medical News Today - Medical News Today (press release)

MAP Pharmaceuticals Initiates Phase 3 Clinical Trial in Patients With...  -  Jul 14, 2008
The therapeutic agent in MAP0004 is dihydroergotamine (DHE), which has a long history of use as a safe and effective migraine treatment. ... Genetic Engineering News - Genetic Engineering News (press release)

MAP Pharmaceuticals Initiates Phase 2a Clinical Trial of Combination ...  -  Oct 31, 2007
...and a proprietary formulation of inhaled dihydroergotamine for the potential treatment of migraine, as well as a proprietary combination of an inhaled ... Free with registration - PR Newswire - AccessMyLibrary.com

Ugandan Children Are Among the First to Receive Abbott's Lower- …  -  Dec 1, 2007
Do not take Kaletra with astemizole, terfenadine, midazolam, triazolam, pimozide, cisapride, ergotamine, dihydroergotamine, ergonovine, and methylergonovine ... Free with registration - PR Newswire - AccessMyLibrary.com

=> Abbott Statement on Agreement With Brazilian Government for...  -  Sep 7, 2005
Kaletra should not be taken with astemizole, cisapride, dihydroergotamine, ergonovine, ergotamine, methylergonovine, midazolam, pimozide, terfenadine or ... FinanzNachrichten.de

MAP Pharmaceuticals Appoints New Program Directors.  -  Jul 19, 2006
...to one of MAP's lead products, a novel inhaled drug formulation of dihydroergotamine mesylate (DHE) administered with MAP's patented Tempo Inhaler. ... Free with registration - PR Newswire - AccessMyLibrary.com

MAP Pharmaceuticals To Present Unit Dose Budesonide Phase 2 Clinical …  -  Jun 23, 2007
...the potential treatment of children with asthma, and a proprietary formulation of inhaled dihydroergotamine for the potential treatment of migraines. ... Medical News Today - Medical News Today (press release)

For best results, consider migraine complex.(Pain Medicine)  -  Feb 1, 2007
..."But as the disability increases, you're more apt to target right away using a specific agent, whether it's a triptan or a dihydroergotamine or ergotamine ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Intranasal NSAID a first for pain relief  -  Jun 7, 2007
Already on the market is Stadol (butorphanol tartrate) analgesic nasal spray and Migranal (dihydroergotamine mesylate) nasal spray for migraines. ... In-PharmaTechnologist.com

Migraine drugs.(DRUGS, PREGNANCY, AND LACTATION)  -  Jan 15, 2005
Others are dihydroergotamine (Migranal, DHE 45), ergotamine (Ergomar) (alone or in combination with caffeine, or caffeine-belladonna-pentobarbital), ... Free with registration - OB GYN News - AccessMyLibrary.com

Long-Term Study Evaluates Boosted PREZISTA(R) Vs. Lopinavir/ …  -  Oct 28, 2008
...events (eg, dihydroergotamine, ergonovine, ergotamine, methylergonovine, cisapride, pimozide, oral midazolam, triazolam, lovastatin, or simvastatin). ... Medical News Today - Medical News Today (press release)

Medications for migraine prophylaxis.  -  Jan 1, 2006
Evidence supports the use of timed-release dihydroergotamine mesylate, but patients should be monitored closely for adverse effects. ... Free with registration - American Family Physician - AccessMyLibrary.com

GlaxoSmithKline (GSK) Data Show Significantly More Patients Were Pain...  -  Jun 27, 2008
Treximet and any ergotamine-containing or ergot-type medication (like dihydroergotamine and methysergide) should not be used within 24 hours of each other. ... Lifescience-online

Tibotec Therapeutics Launches New Dosage Strength for PREZISTA(TM)  -  May 19, 2008
...terfenadine, dihydroergotamine, ergonovine, ergotamine, methylergonovine, cisapride, pimozide, midazolam, or triazolam) and for which elevated plasma ... RedOrbit

African-American Women Who Have Received HIV Treatment Are Sought …  -  Feb 7, 2007
...terfenadine, dihydroergotamine, ergonovine, ergotamine, methylergonovine, cisapride, pimozide, midazolam, or triazolam) and for which elevated plasma ... Medical News Today - Medical News Today (press release)

PRESS RELEASE: MAP Pharmaceuticals Announces Pricing of Its Initial …  -  Oct 8, 2007
...for the potential treatment of children with asthma, and a proprietary formulation of inhaled dihydroergotamine for the potential treatment of migraine. ... FierceBiotech

Manage headaches while pregnant  -  Jan 5, 2007
Ergotamine, dihydroergotamine (DHE) and triptans should be avoided (5, 3). However, a recent study found that sumatriptan did not appear to pose an ... iAfrica.com - iafrica.com

How to take Minocycline Oral from Consumer Reports Health.  -  Jan 10, 2005
...cabergoline (Dostinex), dihydroergotamine (DHE 45, Migranal), ergoloid mesylates (Germinal, Hydergine), ergonovine (Ergotrate), ergotamine (Bellergal-S, ... consumerreports.org

Intranasal delivery  -  Mar 10, 2005
Bristol Myers Squibb Co USA), dihydroergotamine (Migranal nasal spray, Novartis Inc), cromolyn sodium (Nasalcrom nasal solution, Fisons Pharmaceuticals) ... expresspharmapulse.com

Abbott's New Tablet Formulation of Kaletra'R', Lopinavir/Ritonavir, …  -  Sep 12, 2006
Kaletra should not be taken with astemizole, cisapride, dihydroergotamine, ergonovine, ergotamine, methylergonovine, midazolam, pimozide, terfenadine or ... marketwire.com

Boehringer Ingelheim Initiates SPRING Study Of Aptivus(R) (tipranavir)...  -  Jun 15, 2007
APTIVUS/ritonavir is contraindicated with amiodarone, bepridil, flecainide, propafenone, quinidine, astemizole, terfenadine, dihydroergotamine, ergonovine, ... Medical News Today - Medical News Today (press release)

New Abbott Aluvia(R) Tablet for Treatment of HIV Available in South …  -  Mar 6, 2008
Do not take Aluvia with astemizole, terfenadine, midazolam, triazolam, pimozide, cisapride, ergotamine, dihydroergotamine, ergonovine, methylergonovine, ... ITNews

Players Still Trying To Widen Market For Migraine Therapy  -  Aug 20, 2007
Two earlier compounds - MT 300, a new formulation of dihydroergotamine mesylate, and MT 100, a naproxen/metoclopramide combo - got not-approvable letters ... BioWorld Online - BioWorld Online

Rizatriptan (Systemic).  -  Oct 27, 2005
Dihydroergotamine Ergotamine Methysergide Other 5-hydroxytryptamine agonists (naratriptan [eg, Amerge], sumatriptan [eg, Imitrex], zolmitriptan [eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Bromocriptine (Systemic).(Drug overview)  -  May 1, 2006
Ergot alkaloids (dihydroergotamine [eg, DHE 45], ergoloid mesylates [eg, Hydergine], ergonovine [eg, Ergotrate], ergotamine [eg, Gynergen], methylergonovine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

06/18/07 #3 - Joint pain and triptans?  -  Jun 18, 2007
Alternatively, there is a nasal spray form of dihydroergotamine ( Migranal NS ) that might be useful for migraines. Please note: We cannot handle ... HealthCentral.com

Overuse of headache drugs can be overcome.(Neurology)  -  Mar 1, 2007
Inpatients can be switched to intravenous DHE (dihydroergotamine mesylate) and outpatients can be given Migranal NS. A steroid taper is another option, ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Abbott Submits Application To EMEA For A New, More Convenient …  -  Jul 31, 2005
Kaletra should not be taken with astemizole, cisapride, dihydroergotamine, ergonovine, ergotamine, methylergonovine, midazolam, pimozide, terfenadine or ... i-newswire.com

Clarithromycin (Systemic).(Drug overview)  -  May 1, 2006
...(astemizole, cisapride, pimozide, and terfenadine should not be taken with clarithromycin ) Dihydroergotamine (eg, Migranal) or Ergotamine (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

How to take Rizatriptan from Consumer Reports Health.  -  Jan 2, 2008
...and tranylcypromine (Parnate) during the last 2 weeks or if you have taken another medication for migraine headaches such as dihydroergotamine (DHE 45, ... consumerreports.org

Clinical trials update: September 2006.(Report)  -  Oct 16, 2006
Jazz Xyrem Sodium oxybate oral Pharmaceuticals (FDA-approved) solution Inc. * MAP MAP0004 Formulation of Pharmaceuticals dihydroergotamine mesylate Inc. ... Free with registration - Bioworld Financial Watch - AccessMyLibrary.com

Delavirdine (Systemic).(Drug overview)  -  Aug 1, 2006
Alprazolam (eg, Xanax) or Carbamazepine (eg, Tegretol) or Cisapride (eg, Propulsid) or Dihydroergotamine (eg, DHE 45) or Ergonovine (eg, Ergotrate) or ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

This antiviral offers new option to HIV patients.(NEW DRUG)  -  Aug 7, 2006
Use of Prezista is contraindicated with astemizole, terfenadine, dihydroergotamine, ergonovine, ergotamine, methylergonovine, cisapride, pimozide, ... Free with registration - Drug Topics - AccessMyLibrary.com

Nitroglycerin.(Drug overview)  -  Jan 22, 2007
Also be alert for an interaction with dihydroergotamine (DHE). Check with your doctor if you are uncertain about any combination you plan to take. ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Brand Names/Synonyms:
Dihydroergotamine is also known by the following brand names and/or synonymsErgotamine, 9,10-dihydro-; Dihydroergotaminum [INN-Latin]; Dihidroergotamina [INN-Spanish]; D.H.E.; D.H.E. 45; Agit; Angionorm; D.H.E. 45; DET MS; DHE-45; Dergotamine; Diergo; Dihydergot; Dihydroergotamine; Dihydroergotamine mesylate; Dihydroergotamine methanesulfonate; Dihydroergotamine monomethanesulfonate; Dirgotarl; Endophleban; Ergomimet; Ergont; Ergotonin; Ikaran; Migranal; Morena; Orstanorm; Tonopres; Verladyn

Drug Category:
Dihydroergotamine is categorized under the following by the FDA: Analgesics; Vasoconstrictor Agents; Sympatholytics; ATC:N02CA01

Dosage Forms:
LIQUID

Absorption:
Interpatient variable and may be dependent on the administration technique

Interactions:
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Chemical IUPAC Name:
Not Available





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