Disulfiram

This page contains recent news articles, when available, and an overview of Disulfiram but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Disulfiram
(when available)

Pharmacology and use:
Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol. For the treatment and management of chronic alcoholism

Mechanism Of Action:
Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake causing an accumulation of acetaldehyde in the blood producing highly unpleasant symptoms. Disulfiram blocks the oxidation of alcohol through its irreversible inactivation of aldehyde dehydrogenase, which acts in the second step of ethanol utilization. In addition, disulfiram competitively binds and inhibits the peripheral benzodiazepine receptor, which may indicate some value in the treatment of the symptoms of alcohol withdrawal, however this activity has not been extensively studied.

News Articles on Disulfiram

Researchers find vaccine that blocks cocaine's high  -  05 Jan 2010
The idea of developing a medication to block addiction has long been attractive: Disulfiram (now sold under the name Antabuse), which makes people ill if ... Denver Post

How can alcoholism be managed?  -  ‎Nov 12, 2009‎
It is also his paranoia that needs to be addressed so a cocktail of Thorazine, valproic acid,along with Disulfiram and Naltrexone or Thorazine, ... DoctorNDTV

Leishmaniasis: New Strategy To Find Drugs To Treat Neglected Parasitic Infection  -  ‎Nov 2, 2009‎
A promising anti-leishmanial compound they found turned out to be disulfiram, or Antabuse, a drug that causes an acute sensitivity to alcohol and that is ... Science Daily (press release)

Update module 1501: Bacterial vaginosis  -  ‎Nov 3, 2009‎
The main caution to patients is to avoid alcohol, which produces a disulfiram-like reaction. For women who cannot tolerate oral metronidazole, ... Chemist+Druggist

Khắc phục tác dụng phụ cá»§a thuốc cai rượu, ma túy  -  ‎Nov 1, 2009‎
Hiện trên thị trưá»?ng có esperal (disulfiram) viên 500mg, uống vào má»—i buổi sáng, dùng kéo dài tối thiểu 2 năm. Nếu bệnh nhân không uống rượu, bia, ... XãLuận.com tin tức việt nam 24h cập nhật

Alkoholen kidnappar hjärnan  -  ‎Oct 28, 2009‎
Förutom disulfiram (Antabus), som ger kraftiga besvär vid alkoholintag, och de två relativt nya läkemedlen akamprosat, som minskar suget efter alkohol och ... Ergo

Disulfiram - MSN Health & Fitness - Neurological-Cognitive Health  -  Feb 15, 2008
Disulfiram changes the way your body breaks down (metabolizes) alcohol. If you drink alcohol while you are taking disulfiram, you will experience ... MSN Health & Fitness

Disulfiram, Behavior Therapy in Cocaine Dependency  -  Jan 1, 2005
The use of disulfiram in the treatment of cocaine dependence was first introduced in patients who also were abusing alcohol. Disulfiram was thought to ... AAFP News Now

Deal With A Disulfiram Reaction  -  Jul 7, 2007
In this third and last article regarding disulfiram or TETD, we will take a look at disulfiram reaction. This happens when alcohol and disulfiram are ... Buzzle

A Cocaine Vaccine and Disulfiram Show Promise for Cocaine …  -  Dec 6, 2007
December 6, 2007 (Coronado, CA) — Two stimulant-abuse pharmacotherapies — a cocaine vaccine and disulfiram (tetraethylthiuram disulfide) — show promise for ... Medscape

Drug likely causing limp response  -  Nov 7, 2006
Antabuse (Disulfiram), treats chronic alcoholism by discouraging drinking, through extreme reactions like vomiting, throbbing headaches and anxiety. ... Toronto Star

Alcoholism drug disulfiram, other agents target cocaine dependence.(Rx...  -  Feb 1, 2005
NEW YORK -- Disulfiram, a drug that has long been used for alcohol dependence, appears promising for the treatment of cocaine addiction, Thomas Kosten, MD, ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Disulfiram, vaccine may curb cocaine addiction.(Addiction Psychiatry)  -  May 1, 2007
MENDOZA, ARGENTINA -- Two promising pharmacotherapies are currently in clinical trials for treatment of cocaine dependence: disulfiram and a vaccine ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Expectations lowered for disulfiram.(Addiction Psychiatry) | Article...  -  Oct 1, 2008
Expectations lowered for disulfiram.(Addiction Psychiatry) ... find Clinical Psychiatry News articles. VIENNA -- Disulfiram has a far more truncated role in ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Disulfiram Inhibits Defluorination of 18F-FCWAY, Reduces Bone …  -  Jun 15, 2007
Yong Hoon Ryu 1 , Jeih-San Liow 2 , Sami Zoghbi 2 , Masahiro Fujita 2 , Jerry Collins 3 , Dnyanesh Tipre 2 , Janet Sangare 2 , Jinsoo Hong 2 , Victor W. ... Journal of Nuclear Medicine (subscriptio...

New alcoholism treatments  -  Aug 16, 2006
In the old days, doctors prescribed Antabuse (disulfiram), which did indeed make people extremely ill if they consumed alcohol. ... $2.95 - Buffalo News - NewsBank

Alcohol Problems? Want To Try Disulfiram?  -  May 12, 2007
For almost fifty years, disulfiram or TETD, has been a staple for alcohol addicts trying to quit. It is estimated that about 200000 people use the ... Buzzle

Handle with care - How to choose a quality treatment program  -  Dec 22, 2006
Methadone, naltrexone and disulfiram (antabuse) can be effective in helping some addicts. Staff should discuss them with patients. ... $2.95 - Fort Worth Star-Telegram - NewsBank

Alcoholism drug disulfiram, other agents target cocaine dependence.(Rx...  -  Feb 1, 2005
Alcoholism drug disulfiram, other agents target cocaine dependence.(Rx) ... find Internal Medicine News articles. NEW YORK -- Disulfiram, a drug that has ... Pay-Per-View - Internal Medicine News - HighBeam Research

Adverse Drug Reaction; Disulfiram-induced liver injury clarified  -  May 31, 2006
2006 MAY 31 - (NewsRx.com) -- Recent research from Sweden has chronicled the clinical characteristics and prognostic markers in disulfiram-induced liver ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Oncology; Reports add new data to oncology research  -  Apr 4, 2005
Using melanoma as the paradigm, we tested whether disulfiram might inhibit growth ... "Disulfiram given to melanoma cells in combination with Cu2+ or Zn2+ ... Pay-Per-View - Clinical Oncology Week - Factiva, from Dow Jones

Long-term, high-dose disulfiram in the treatment of alcohol abuse  -  Feb 1, 2006
A patient who had experienced most of the standard methods of managing alcohol abuse found that during 11 years of treatment, the most consistently ... British Journal of Psychiatry (subscript...

Oncology; Reports advance knowledge in oncology research  -  Feb 14, 2005
Using melanoma as the paradigm, we tested whether disulfiram might inhibit growth ... "Disulfiram given to melanoma cells in combination with Cu2+ or Zn2+ ... Pay-Per-View - Cancer Gene Therapy Week - Factiva, from Dow Jones

Medications for alcohol dependence treatment: lessons from the...  -  Mar 1, 2007
Disulfiram is an older drug with which many clinicians are familiar. Compliance to disulfiram therapy is a common barrier to its use, and clinical trials ... Free with registration - Addiction Professional - AccessMyLibrary.com

Article: Disulfiram, vaccine may curb cocaine addiction.(Addiction …  -  May 1, 2007
Disulfiram, vaccine may curb cocaine addiction.(Addiction Psychiatry) ... find Clinical Psychiatry News articles. MENDOZA, ARGENTINA -- Two promising ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Medications for treating alcohol dependence.  -  Nov 1, 2005
Disulfiram, an aversive agent that has been used for more than 40 years, ... Although in two trials oral disulfiram was shown to reduce frequency of ... Free with registration - American Family Physician - AccessMyLibrary.com

Study Says Drugs Help Alcoholics Stay Sober  -  Jan 6, 2006
Third, sham-ADs are as efficient as disulfiram or calcium carbimide, provided that the use is repeatedly explained and continuously guided and encouraged," ... JoinTogether.org

A review of the pharmacologic options for the treatment of alcohol …  -  Jan 1, 2007
Disulfiram treatment has yielded inconsistent results in reducing alcohol ... In general, since disulfiram treatment has not demonstrated long-term efficacy ... $4.95 - Formulary - ECNext

disulfiram | Definition of disulfiram | HighBeam.com: Online Dictionar...  -  Jul 12, 2006
Find out what disulfiram means: The Oxford American College Dictionary has the definition of disulfiram. Research related newspaper, magazine, ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

Alcohol-deterrent drugs help patients achieve high rates of long-term...  -  Apr 1, 2006
Conversely, disulfiram use is certainly common in Spain, Portugal, Germany, ... Carefully prepared and supervised intake of disulfiram or calcium carbimide ... innovations report

Alcohol-deterrent drugs help patients achieve high rates of long-term...  -  Jan 3, 2006
Conversely, disulfiram use is certainly common in Spain, Portugal, Germany, ... Carefully prepared and supervised intake of disulfiram or calcium carbimide ... eurekalert.org

Disulfriam or TETD side effects part 2  -  Jun 7, 2007
This is the second part of the disulfiram or TETD article we started last month. As most of you probably knows, disulfiram is a medical alcoholism treatment ... Buzzle

Alcohol-deterrent drugs help long-term abstinence  -  Jan 8, 2006
Conversely, disulfiram use is certainly common in Spain, Portugal, Germany, ... Carefully prepared and supervised intake of disulfiram or calcium carbimide ... News-Medical.net

FÃ¥r medisin mot alkoholisme  -  Sep 18, 2008
I fjor ble det registrert i alt 4062 brukere av brusetabletten disulfiram (Antabus), det mest brukte legemiddelet ved alkoholisme. ... Varden

Oncology; New data illuminates research in oncology  -  Mar 11, 2005
Using melanoma as the paradigm, we tested whether disulfiram might inhibit growth ... "Disulfiram given to melanoma cells in combination with Cu2+ or Zn2+ ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Oncology; New data illuminates research in oncology  -  Mar 8, 2005
Using melanoma as the paradigm, we tested whether disulfiram might inhibit growth ... "Disulfiram given to melanoma cells in combination with Cu2+ or Zn2+ ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Physiological therapies  -  Jun 16, 2008
However, in the presence of disulfiram—itself harmless—the metabolism of ... The usual technique is to administer one-half gram of disulfiram in tablet form ... Subscription - Encyclopedia Britannica

Oncology; Reports advance knowledge in oncology research  -  Feb 15, 2005
Using melanoma as the paradigm, we tested whether disulfiram might inhibit growth ... "Disulfiram given to melanoma cells in combination with Cu2+ or Zn2+ ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Oncology; Reports advance knowledge in oncology research  -  Feb 18, 2005
Using melanoma as the paradigm, we tested whether disulfiram might inhibit growth ... "Disulfiram given to melanoma cells in combination with Cu2+ or Zn2+ ... Pay-Per-View - Genomics & Genetics Weekly - Factiva, from Dow Jones

Medscape Perspectives on the 2007 Annual Sessions of the American …  -  May 23, 2007
Disulfiram has been used for alcohol dependence, and several clinical trials ... [3] Dr. Kampman said that this is because disulfiram raises serum cocaine ... Medscape

What happens when you drink  -  Aug 1, 2006
Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage. During alcohol metabolism, after Disulfiram intake, the concentration of acetaldehyde ... Daily Star - The Daily Star

Easy on the pills  -  Nov 9, 2005
Disulfiram is a well-established adjunct to other methods in the treatment ... Disulfiram is not prescribed to those with serious cardiovascular conditions ... Malaysia Star

Drug treatment for alcoholism today.  -  Jul 1, 2005
Disulfiram (Antabuse) prevents the liver from metabolizing alcohol normally and ... If they drink, patients taking disulfiram can become nauseated and even ... $4.95 - Harvard Mental Health Letter - ECNext

:The Daily Star: Internet Edition  -  Jan 20, 2008
Disulfiram is a drug that produces sensitivity to alcohol. ... Disulfiram blocks the oxidation of alcohol to acetaldehyde during metabolism and produces ... Daily Star - The Daily Star

O simpla injectie cu un virus poate combate alcoolismul  -  Jun 26, 2007
Reactia disulfiram- alcool se caracterizeaza prin greata, cefalee pulsatila, ... "Daca, insa iei disulfiram zilnic, apare o problema de rezistenta la acest ... Obiectiv de Suceava

Old drugs, new function in cocaine dependence.(Mental Health) |...  -  Jan 15, 2005
NEW YORK -- Disulfiram, a drug that has long been used for alcohol dependence, appears promising for the trea... Pay-Per-View - Family Practice News - HighBeam Research

Promising medications lend hope to addicts seeking treatment.  -  Aug 8, 2005
Other drugs used to treat addiction are methadone and disulfiram. ... Disulfiram, which is sold under the trade name Antabuse, has been used to treat ... Free with registration - St. Louis Post-Dispatch - AccessMyLibrary.com

Continuing education quiz.  -  Jul 1, 2007
Disulfiram c. Acamprosate 7. This medication for the treatment of alcohol ... Disulfiram c. Acamprosate 8. This medication may be particularly suited to ... Free with registration - Addiction Professional - AccessMyLibrary.com

Medications help break the bonds of addiction  -  Jul 31, 2005
Other drugs used to treat addiction are methadone and disulfiram. ... Disulfiram, which is sold under the trade name Antabuse, has been used to treat ... Pay-Per-View - St. Louis Post-Dispatch - Factiva, from Dow Jones

Article: The new antidipsotropics.(RX Primer) - Annals of the...  -  Dec 22, 2006
Antidipsotropics, or drugs that decrease drinking like disulfiram ... It does not affect the pharmacokinetics of alcohol, disulfiram, diazepam, ... Pay-Per-View - Annals of the American Psychotherapy... - HighBeam Research

The new antidipsotropics.(RX Primer)  -  Dec 22, 2006
Antidipsotropics, or drugs that decrease drinking like disulfiram ... It does not affect the pharmacokinetics of alcohol, disulfiram, diazepam, ... $4.95 - Annals of the American Psychotherapy... - ECNext

Schizophrenia, substance use need integrated Tx: take into account...  -  Jan 1, 2007
Developing research suggests that disulfiram (Antabuse) and naltrexone (ReVia) may be effective in this population (Schizophr. Bull. 2006;32:644-54), ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Trunksüchtige Ratten  -  Jan 24, 2008
Die dritte Behandlungsform namens Disulfiram wirkt ähnlich wie Israels Gentherapie – den Menschen wird beim Trinken sofort schlecht. ... heise.de

Có nên lén cho chồng uống thuốc cai nhậu ?  -  Sep 27, 2007
Thuốc có tên Espéral mà em h�i chính là disulfiram (ngoài Espéral, disulfiram còn có tên biệt ... Tác dụng của disulfiram là ngăn chặn sự chuyển hóa rượu, ... Tin nhanh

STEPS - August 15, 2006 -- American Family Physician  -  Aug 15, 2006
In 2004 it became the third drug to receive approval from the US Food and Drug Administration for this indication, following disulfiram (Antabuse) and ... AAFP News Now

Wilhelm S. slikte middel dat kans op psychose verhoogt  -  Jun 24, 2005
Gebruikers van de stof disulfiram kunnen psychotisch worden. ... Antabus bevat de chemische stof disulfiram. De stof wordt toegepast bij het vulkaniseren ... Trouw

Genetic approaches to alcohol dependence *  -  Jan 15, 2008
This is rather like having endogenous disulfiram permanently on board (disulfiram, prescribed to aid the maintenance of abstinence, acts by destroying the ... British Journal of Psychiatry (subscript...

A Good Use for a Bad Vine  -  Jun 2, 2005
One of the most widely prescribed alcohol deterrents is called disulfiram (Antabuseâ„¢). Disulfiram discourages drinking by causing severely unpleasant ... Medfinds

Medications for the treatment of alcohol dependence.(Letters to the...  -  Dec 1, 2006
For disulfiram (Antabuse), Table 1 recommends a starting dosage of 250 mg per day ... (1) Some patients do require higher doses of disulfiram to ensure the ... Free with registration - American Family Physician - AccessMyLibrary.com

Lecturer touts drug to cure cocaine addiction  -  Mar 18, 2005
One of Kosten's chemicals is Disulfiram - trade name Antabuse. Several studies, including those by his research team at Yale, demonstrated that those taking ... Amarillo.com

Alcoolicii recunosc foarte greu ca sint dependenti  -  Feb 13, 2007
Nestiind exact ce medicament ii dati - deoarece nu ati specificat - ma refer la asa-numitul Antalcool ce contine substanta activa disulfiram (disulfiramul ... Ziarul de IaÅŸi - Ziarul de IaÅŸi

Therapie extrem  -  May 17, 2006
Denn die Aversiva-Wirkstoffe Calciumcarbimid und Disulfiram verhindern ... Bereits in den fünfziger Jahren wurden Disulfiram und Calciumcarbimid eingesetzt. ... ZEIT ONLINE

Arteriosclerosis; Aldehyde dehydrogenase 2 involved in human …  -  Oct 25, 2005
They found that, while "all drugs caused a dose-dependent vasodilatation," only "the response to NTG was significantly reduced after disulfiram therapy (33% ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Arteriosclerosis; Aldehyde dehydrogenase 2 involved in human …  -  Oct 30, 2005
They found that, while "all drugs caused a dose-dependent vasodilatation," only "the response to NTG was significantly reduced after disulfiram therapy (33% ... Pay-Per-View - Heart Disease Weekly - Factiva, from Dow Jones

Medications for the treatment of alcohol dependence.(Letters to the...  -  Dec 1, 2006
For disulfiram (Antabuse), Table 1 recommends a starting dosage of 250 mg per day ... (1) Some patients do require higher doses of disulfiram to ensure the ... $4.95 - American Family Physician - ECNext

Medications for Cocaine Abuse  -  Feb 1, 2005
In addition to its effects on alcohol metabolism, disulfiram also blocks the ... There are now three published trials showing that disulfiram reduces ... Pay-Per-View - Psychiatric Times - Factiva, from Dow Jones

Alcohol dependence.(medications for alcoholism underused) | Article …  -  Mar 1, 2006
Conventional naltrexone and disulfiram are dosed as once-daily tablets. ... The limited efficacy of disulfiram prompts some experts to say that its benefit ... Pay-Per-View - Internal Medicine News - HighBeam Research

Antabuse | Definition of Antabuse | HighBeam.com: Online Dictionary  -  Jul 12, 2006
Disulfiram (Antabuse) is a prescription medication ... social complications of your drug abuse. ... ReVia (naltrexone, 41%), or Antabuse (disulfiram, 27%). ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

La Nacion.cl - Tecnología  -  Apr 9, 2008
Desde la década de los 50 se utiliza disulfiram, droga descubierta por accidente ... El tratamiento con disulfiram utilizado en la actualidad incluye desde ... La Nación - La Nación (Chile)

Medicines and alcohol  -  Sep 28, 2005
Antibacterials – A disulfiram-like reaction can occur when alcohol is taken with metronidazole. The reaction includes flushing of the face, ... Malaysia Star

Methodencheck: Weg von der Flasche  -  Mar 10, 2008
Zudem kann bei sorgfältiger Überwachung durch einen Arzt Disulfiram als Aversivtherapeutikum eingenommen werden (Disulfiram ist kein Anti-Craving- ... STERN.DE

Article: Lymphangiogenesis tied to melanoma metastasis risk.(Clinical...  -  Jul 1, 2005
Article: Disulfiram combats melanoma metastasis. Clinical Oncology Week; November 22, 2004 ; 700+ words ...2004 NOV 22 - (NewsRx.com & NewsRx.net) ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Article: Chelating agent for multi-component compound fertilizers.(Bri...  -  Jun 6, 2005
Article: The zinc-chelating agent disulfiram may have ... AIDS Weekly; December 8, 2003 ; 700+ words ... ... 8 - (NewsRx.com & NewsRx.net) -- The ... Pay-Per-View - China Chemical Reporter - HighBeam Research

Evidence-Based Treatments for Alcohol Dependence  -  May 3, 2006
2-3 This followed by nearly 50 years the approval of disulfiram, ... 4 In contrast to disulfiram, which produces an aversive reaction when combined with ... Journal of American Medical Association - Journal of American Medical Association...

ARSENAL FOR ADDICTS  -  Apr 20, 2005
Currently approved: naltrexone, disulfiram (Antabuse), acamprosate (Campral) ... Under study: baclofen, disulfiram (Antabuse), modafinil (Provigil), ... Pay-Per-View - Daily Press - ProQuest Archiver

Proyecto Fondef de la Universidad de Concepción propone mejoras para …  -  Apr 27, 2005
Nueva formulación farmacéutica de disulfiram, como apoyo al tratamiento ... Una nueva tecnología para elaborar una formulación de disulfiram espera ... universia.cl

Raus aus der Alkoholsucht mit „Antabus“?  -  Dec 10, 2007
...„Antabus“ mit dem Wirkstoff Disulfiram hemmt das alkoholabbauende Enzym ... Heute wird der Wirkstoff Disulfiram nur eingesetzt, wenn Patienten dies – in ... WDR Nachrichten

A type of virus could help kick drinking  -  Jun 24, 2007
Aldehyde dehydrogenase is blocked by the drug disulfiram, also known as Antabuse, ... "But you have to take it (disulfiram) every day, so there is a big ... Daily News & Analysis

Treating alcohol dependence.(MINDFUL PRACTICE)(Column)  -  Dec 15, 2005
We added the term "NOT disulfiram" and limited the search to "randomized controlled trial." Like other pharmacologic studies in the field of alcoholism, ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Echinacea (Echinacea purpurea)  -  Aug 1, 2005
The high alcohol content in some echinacea tinctures may lead to vomiting if used with the drugs disulfiram (Antabuse) or metronidazole (Flagyl). ... Intelihealth.com

Late-life alcohol abuse: finding solutions to a hidden medical...  -  Jan 1, 2005
For instance, disulfiram makes drinking repugnant by unleashing vomiting, nausea, facial flushing and other symptoms if alcohol is consumed. ... Free with registration - Brown University Geriatric Psychopharmac... - AccessMyLibrary.com

Cannabis.  -  Aug 1, 2006
Lacoursiere RB & Swateck R:Adverse interaction between disulfiram and marijuana. Am J Psychiatry 1983; 140: 243-244. (3.) Product Information: Norvir(TM), ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Alcohol Dependence (Alcoholism)  -  Jul 6, 2007
As an alternative, sometimes the drug disulfiram (Antabuse) may be prescribed. This drug does not reduce craving, but it creates an incentive not to drink, ... Intelihealth.com

Cranberry (Vaccinium macrocarpon)  -  Jun 2, 2005
The high alcohol content in some cranberry tinctures may lead to vomiting if used with the drug disulfiram (Antabuse) or metronidazole (Flagyl). ... Intelihealth.com

Isoniazid (Systemic).  -  Oct 27, 2005
There may also be an increased chance of side effects of carbamazepine and phenytoin Disulfiram (eg, Antabuse) -- This medicine may increase the chance of ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Helping patients who drink too much.(Clinical Guidelines For Family …  -  Nov 15, 2005
Disulfiram (Antabuse) produces an unpleasant flushing reaction when a patient drinks. Disulfiram should not be used in patients with coronary artery disease ... Free with registration - Family Practice News - AccessMyLibrary.com

Cannabis.(Drug overview)  -  Feb 1, 2007
Lacoursiere RB & Swateck R:Adverse interaction between disulfiram and marijuana. Am J Psychiatry 1983; 140:243-244. (3.) Product Information: Norvir(TM), ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Tinidazole (Systemic).  -  Feb 1, 2006
Disulfiram (eg, Antabuse) -- Tell your doctor if you have taken disulfiram in the two weeks before starting tinidazole. Lithium -- Patients taking lithium ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Sertraline (Systemic).(Drug overview)  -  May 1, 2006
Your doctor may need to change the dose of either these medicines or sertraline Disulfiram (eg, Antabuse) -- Disulfiram will react with the alcohol in ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Cannabis.  -  May 1, 2006
Lacoursiere RB & Swateck R:Adverse interaction between disulfiram and marijuana. Am J Psychiatry 1983; 140:243-244. (3.) Product Information: Norvir(TM), ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Continuing education quiz.  -  Sep 1, 2007
Disulfiram c. Acamprosate 7. Better communication of what the counselor knows about the patient might help lift this barrier to physicians' addressing ... Free with registration - Addiction Professional - AccessMyLibrary.com

Sertraline (Systemic).  -  Feb 1, 2006
Your doctor may need to change the dose of either these medicines or sertraline Disulfiram (eg, Antabuse) -- Disulfiram will react with the alcohol in ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

16th Meeting of the American Academy of Addiction Psychiatry: …  -  Dec 8, 2005
Disulfiram was approved more than 50 years ago and is an aversive treatment that works by causing an unpleasant reaction if alcohol is consumed. ... Medscape

Clinical quiz.  -  Nov 1, 2005
Which one of the following statements about disulfiram (Antabuse) is correct? ... A. Disulfiram (Antabuse). [] B. Acamprosate (Campral). ... Free with registration - American Family Physician - AccessMyLibrary.com

Avhengighet - faktaark  -  Feb 12, 2008
Disulfiram (Antabus) hemmer et trinn i nedbrytningen av alkohol i kroppen, ... Man vil føle ubehag hvis man bruker alkohol og disulfiram samtidig, ... folkehelseinstituttet

Best fikk hjelp av norsk lege  -  Dec 2, 2005
Behandling av alkoholisme med disulfiram er ingen lettvint måte å behandle alkoholmisbruk på. Metoden kan være av betydelig nytte for en pasient i en ... Dagbladet.no

SierpieÅ„ to dobra pora, żeby siÄ™ napić. Albo rzucić picie...  -  Aug 27, 2006
W lecznictwie otwartym najczęściej podaje się anticol (disulfiram) lub wszczepia esperal (disulfiram), stosuje się psychoterapię indywidualną i grupową, ... Wiadomosci 24

Alcohol withdrawal.(Adult Health Adviser 2007)(Disease/Disorder …  -  May 31, 2007
Disulfiram (Antabuse) will make you feel sick if you drink alcohol after taking the medicine. Knowing you will have this reaction will discourage you from ... $4.95 - Clinical Reference Systems - ECNext

New York Codes, Rules and Regulations - 14 NYCRR 372.10. Program.  -  May 18, 2007
...(2) If the facility permits the prescription, dispensing or administration of disulfiram or psychotropic medications for treatment of concurrent mental ... Pay-Per-View - New York Codes, Rules and Regulations - Loislaw

Press Release: Advanced Biological Laboratories SA (ABL, SA) Acquires...  -  Feb 22, 2005
US Fed News Service, Including US State News; July 10, 2009 ; 409 words ... ... disulfiram. The patent has been assigned to Universidad de Concepcion, ... Pay-Per-View - PR Newswire - HighBeam Research

New medications for addictions carry lower risk of relapse.(Psychiatry...  -  Aug 1, 2007
Four drugs have been approved for treatment: disulfiram (Antabuse), naltrexone (ReVia) ... Disulfiram works best in patients who are motivated, intelligent, ... $4.95 - Internal Medicine News - ECNext

Article: Design and analysis of trials of combination therapies *. -...  -  Jul 1, 2005
In alcohol dependence, two categories of interventions with direct mechanisms of action have not consistently demonstrated efficacy: disulfiram (acting to ... Pay-Per-View - Journal of Studies on Alcohol - HighBeam Research

Alcohol withdrawal.(Women's Health Advisory 2006)(Disease/Disorder …  -  Nov 1, 2006
Disulfiram (Antabuse) will make you feel sick if you drink alcohol after taking the medicine. Knowing you will have this reaction will discourage you from ... $4.95 - Clinical Reference Systems - ECNext

Indiana Acts - PL 172-2006 — HOUSE ENROLLED ACT No. 1128 of …  -  Mar 24, 2006
...treatment program in which the person is taking disulfiram or a similar substance that the court determines is effective in treating alcohol abuse. ... Pay-Per-View - Indiana Acts - Loislaw

Dual diagnosis? Treat substance abuse first.(methods of treating...  -  Mar 1, 2006
For-alcohol abusers, he mostly relies on disulfiram, but he acknowledges that what works and is ... "A lot of clinicians shy away from disulfiram," he said. ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Alcohol withdrawal.(care and treatment)(Disease/Disorder overview)  -  May 24, 2006
Disulfiram (Antabuse) will make you feel sick if you drink alcohol after taking the medicine. Knowing you will have this reaction will discourage you from ... $4.95 - Clinical Reference Systems - ECNext

Brand Names/Synonyms:
Disulfiram is also known by the following brand names and/or synonymsAbstensil; Abstinil; Abstinyl; Accel Tet; Accel Tet-R; Akrochem Tetd; Alcophobin; Alk-Aubs; Ancazide Et; Antabus; Antabuse; Antadix; Antaenyl; Antaethan; Antaethyl; Antaetil; Antalcol; Antetan; Antethyl; Antetil; Anteyl; Anthethyl; Anti-Ethyl; Antiaethan; Anticol; Antietanol; Antietil; Antikol; Antivitium; Aversan; Averzan; Bonibal; Contralin; Contrapot; Cronetal; Dicupral; Disetil; Disulfan; Disulfiram; Disulfram; Disulfuram; Disulphuram; Dupon 4472; Dupont Fungicide 4472; Ekagom Dtet; Ekagom Teds; Ekagom Tetds; Ekaland Tetd; Ephorran; Espenal; Esperal; Etabus; Ethyl Thiram; Ethyl Thiudad; Ethyl Thiurad; Ethyl Tuads; Ethyl Tuads Rodform; Ethyl Tuex; Ethyldithiourame; Ethyldithiurame; Etyl Tuex; Exhoran; Exhorran; Gababentin; Hoca; Hocakrotenalnci-C02959; Krotenal; NCI-C02959; NSC 190940; Nocbin; Nocceler Tet; Nocceler Tet-G; Noxal; Perkacit Tetd; Perkait Tetd; Refusal; Ro-Sulfiram; Sanceler Tet; Sanceler Tet-G; Soxinol Tet; Stopaethyl; Stopethyl; Stopety; Stopetyl; Super Rodiatox; TATD; TETD; TTD; TTS; Tenurid; Tenutex; Tetidis; Tetradin; Tetradine; Tetraethylthioperoxydicarbonic Diamide; Tetraethylthiram Disulfide; Tetraethylthiram Disulphide; Tetraethylthiuram; Tetraethylthiuram Disulfide; Tetraethylthiuram Disulphide; Tetraethylthiuram Sulfide; Tetraethylthiuran Disulfide; Tetraetil; Teturam; Teturamin; Thiocid; Thiophos; Thiosan; Thioscabin; Thireranide; Thiuram Disulfide, Tetraethyl-; Thiuram E; Thiuranide; Tillram; Tiuram; Tts X; Tuads, Ethyl; Usaf B-33

Drug Category:
Disulfiram is categorized under the following by the FDA: Alcohol Deterrents; Enzyme Inhibitors; ATC:N07BB01; ATC:P03AA04

Dosage Forms:
TABLET

Absorption:
Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Interactions:
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Chemical IUPAC Name:
1-(diethylthiocarbamoyldisulfanyl)-N,N-diethyl-methanethioamide





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