Doxorubicin Hydrochloride

This page contains recent news articles, when available, and an overview of Doxorubicin Hydrochloride but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Doxorubicin Hydrochloride
(when available)

Pharmacology and use:
Doxorubicin is an antineoplastic in the anthracycline class. General properties of drugs in this class include: interaction with DNA in a variety of different ways including intercalation (squeezing between the base pairs), DNA strand breakage and inhibition with the enzyme topoisomerase II. Most of these compounds have been isolated from natural sources and antibiotics. However, they lack the specificity of the antimicrobial antibiotics and thus produce significant toxicity. The anthracyclines are among the most important antitumor drugs available. Doxorubicin is widely used for the treatment of several solid tumors while daunorubicin and idarubicin are used exclusively for the treatment of leukemia. Doxorubicin may also inhibit polymerase activity, affect regulation of gene expression, and produce free radical damage to DNA. Doxorubicin possesses an antitumor effect against a wide spectrum of tumors, either grafted or spontaneous. The anthracyclines are cell cycle-nonspecific. For the Treatment of Koposi's sarcome connected to AIDS

Mechanism Of Action:
Doxorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Doxorubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.

News Articles on Doxorubicin

Abraxis BioScience Launches Doxorubicin Hydrochloride Injection, USP.  -  Aug 8, 2007
LOS ANGELES -- Abraxis BioScience, Inc. (NASDAQ:ABBI), an integrated, global biopharmaceutical company, today announced that its hospital-based products ... Free with registration - Business Wire - AccessMyLibrary.com

… Code - 77 Ill. Adm. Code 790.3350 DOXORUBICIN HYDROCHLORIDE ( …  -  Aug 10, 2005
77 Ill. Adm. Code 790.3350 DOXORUBICIN HYDROCHLORIDE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

Doxorubicin Hydrochloride Injection (DBL)  -  Jul 12, 2007
Doxorubicin Hydrochloride for Injection (DBL) can also be used in the management of non-metastatic carcinoma of the bladder, where it is administered ... Virtual Medical Centre - The Virtual Medical Centre

DOXORUBICIN HYDROCHLORIDE LIPOSOME (Intravenous route) - dox- …  -  May 1, 2007
Myocardial damage may lead to congestive heart failure and may be encountered as the total cumulative dose of doxorubicin hydrochloride (HCl) approaches 550 ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Doxorubicin hydrochloride injection USP.  -  Sep 3, 2007
Doxorubicin hydrochloride injection USP, an alternative to Pharmacia's branded drug Adriamycin PFS, is a cytotoxic anthracycline antibiotic used to produce ... $9.94 - Drug Topics - Alacra Store

Doxorubicin hydrochloride injection USP.(NEW GENERICS)(Brief article)  -  Sep 3, 2007
Doxorubicin hydrochloride injection USP, an alternative to Pharmacia's branded drug Adriamycin PFS, is a cytotoxic anthracycline antibiotic used to produce ... $4.95 - Drug Topics - ECNext

… two other generic products. Doxorubicin hydrochloride injection,...  -  Sep 3, 2007
Doxorubicin hydrochloride injection, USP, 2 mg/mL, is a generic equivalent to Bedford's Adriamycin PFS. APP has also launched two other generic products. ... $9.94 - Drug Topics - Alacra Store

Australia: Pharmaceutical Patent Infringement - Interlocutory...  -  May 15, 2008
Interpharma intended to import into Australia and thereafter sell and distribute ready-to-use solutions containing doxorubicin hydrochloride and epirubicin ... Mondaq News Alerts - Mondaq News Alerts (Registration)

Australia: Interlocutory Injunctions for Pharmaceutical Patent...  -  Mar 15, 2006
Under that licence, Pfizer manufactures and sells ready-to-use solutions of doxorubicin hydrochloride and epirubicin hydrochloride. ... Mondaq News Alerts - Mondaq News Alerts (Registration)

Press Release: Poniard Announces Positive Efficacy and Safety Data …  -  Jun 1, 2008
CAELYX(R) (pegylated liposomal doxorubicin hydrochloride) be approved ... the treatment of advanced ovarian cancer in women who have failed ... approved to ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: NICE Recommends Champixq(R) (Varenicline tartrate) …  -  May 30, 2007
Final Appraisal Determination Paclitaxel, pegylated liposomal doxorubicin hydrochloride and topotecan for second-line or subsequent treatment ... ... Pay-Per-View - PR Newswire Europe - HighBeam Research

WHO expert committee on specifications for pharmaceutical preparations...  -  Aug 1, 2005
...hydrochloride 100mg 192159 9930292 doxorubicin hydrochloride 100mg 196202 9930294 emetine hydrochloride 100mg 187134 9930197 4-epianhydrotetracycline ... Free with registration - Technical Report Series - AccessMyLibrary.com

An overview of canine histiocytic disorders: the disorders that arise...  -  Jul 1, 2007
...retrievers treated with various combinations of surgery, chemotherapy (lomustine or doxorubicin hydrochloride), radiation therapy, and corticosteroids. ... Free with registration - Veterinary Medicine - AccessMyLibrary.com

A case of Castleman's disease that presented as a retroperitoneal mass  -  Oct 2, 2006
...aggressive combination chemotherapy with cyclophosphamide, doxorubicin hydrochloride, vincristine, and prednisone (CHOP) results in a durable, ... Nature.com

Tiny diamond patch hailed as a breakthrough in fight against cancer  -  Oct 20, 2008
...coated with a widely used chemotherapy drug called doxorubicin hydrochloride and then arranged into clusters. Each cluster comprises 25 to 50 diamonds. ... Daily Mail

Undertreatment of Obese Women Receiving Breast Cancer …  -  Jun 13, 2005
Methods We performed a retrospective cohort study of 9672 women treated with doxorubicin hydrochloride and cyclophosphamide between 1990 and 2001. ... Archives of Internal Medicine

Outbreak of Fusarium Keratitis in Soft Contact Lens Wearers in San …  -  Jun 12, 2006
The fourth case occurred in a 56-year-old female soft contact lens wearer undergoing CHOP chemotherapy (cyclophosphamide, doxorubicin hydrochloride, ... Archives of Ophthalmology

Loislaw Federal District Court Opinions - PHARMACIA & UPJOHN v. …  -  Aug 17, 2006
...doxorubicin hydrochloride and epirubicin hydrochloride dissolved in a physiologically acceptable aqueous solvent, having a pH adjusted to from 2.5 to ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

California Code of Regulations - § 27:27001. Chemicals Known to the …  -  Jul 30, 2008
1990 Diuron 330-54-1 May 31, 2002 Doxorubicin hydrochloride (Adriamycin) 25316-40-9 July 1, 1987 Epichlorohydrin 106-89-8 October 1, 1987 Erionite ... Pay-Per-View - California Code of Regulations - Loislaw

FDA approves drug for relapsed ovarian cancer  -  Feb 7, 2005
Doxorubicin hydrochloride liposome injection, marketed as DOXIL® in the United States by Tibotec Therapeutics, Division of Ortho Biotech Products, ... Cancerfacts.com

Treatment of diffuse large B-cell lymphoma of the liver with yttrium...  -  Sep 25, 2007
The patient was treated with six cycles of rituximab, cyclophosphamide, vincristine, doxorubicin hydrochloride, and prednisone and showed a partial response ... Nature.com

Transcatheter Arterial Chemoembolization Has Minimal Toxicity in …  -  Apr 6, 2005
Patients underwent treatment that consisted of an emulsion of ethiodol oil and a chemotherapy cocktail that included cisplatin, doxorubicin hydrochloride, ... DG News

About 60 Clinical Studies Regarding Schering-Plough's Oncology …  -  May 31, 2008
Data will be presented on TEMODAR(R) (temozolomide) Capsules, CAELYX(R) (pegylated liposomal doxorubicin hydrochloride), INTRON(R) A (Interferon alfa-2b, ... Medical News Today - Medical News Today (press release)

Cancer Gene Therapy; Antisense oligonucleotide enhances doxorubicin …  -  May 3, 2006
Biotechnology, Dermal Fibroblast, Doxorubicin, Doxorubicin Hydrochloride, Gene Therapy, Oligonucleotide, Oncology, Pharmaceuticals, Synovial Sarcoma. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Drug Delivery; Novel assay measures bioavailable liposomal doxorubicin...  -  Nov 29, 2005
Keywords: Edmonton, Alberta, Canada, Bedford Laboratories, Bioavailability, Breast Cancer, Breast Carcinoma, Doxorubicin Hydrochloride, Drug Delivery, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Nanotechnology cancer treatment with diamonds  -  Nov 7, 2008
Nanodiamonds and doxorubicin hydrochloride molecules bound through physical interactions in various configurations are deposited atop a base layer of ... Nanowerk LLC

Hospira Inc intends a stock buyback - Deal Snapshot - AlacraStore.com  -  Feb 28, 2006
M Dacarbazine HOSPIRA Cancer M Daunorubicin HOSPIRA Cancer M Doxorubicin hydrochloride HOSPIRA Cancer M Etoposide HOSPIRA Cancer M Fudrt Cancer M… ... Pay-Per-View - deals - Alacra Store

Article: Not enough space for visitors - New Straits Times | HighBeam...  -  Mar 26, 2007
...immune stimulator and is under investigation ... evaluating the relative efficacy and safety of KLH versus Adriamycin(R) (doxorubicin hydrochloride ... ... Pay-Per-View - New Straits Times - HighBeam Research

Doxorubicin; Cells respond differently to doxorubicin  -  Oct 27, 2005
Anthracycline, Anticancer Therapy, Breast Cancer, Breast Carcinoma, Cancer Therapy, Cytotoxic Activity, Doxorubicin Hydrochloride, Drug Accumulation, ... Pay-Per-View - Women's Health Weekly - Factiva, from Dow Jones

Breast Cancer; Breast cancer recurrence rate lowered by biweekly …  -  Jun 14, 2006
Keywords: Houston, Texas, United States, Breast Cancer, Breast Carcinoma, Chemotherapy, Cyclophosphamide, Doxorubicin Hydrochloride, Cancer Drugs, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

INSERM E 0211 Nutrition, Tours; Cells respond differently to doxorubic...  -  Oct 26, 2005
Anthracycline, Anticancer Therapy, Breast Cancer, Breast Carcinoma, Cancer Therapy, Cytotoxic Activity, Doxorubicin Hydrochloride, Drug Accumulation, ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Cervical Cancer; Pegylated liposomal doxorubicin has limited activity...  -  Sep 25, 2006
Clinical Trials, Liposomal Delivery, Doxorubicin Hydrochloride, Gynecology, Liposomal Doxorubicin, Liposomes, Medical Device, Oncology, Women's Health. ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones

Study report: effects of combined treatment with Haelan 951 and …  -  Jun 1, 2007
Active agent: doxorubicin hydrochloride 10 mg in 5 ml bottle (2 [micro]g/[micro]l). Antibiotic, anti-tumor agent. HEXAL AG. 83607 Holzkirchen, Germany. ... Free with registration - Townsend Letter for Doctors and Patients - AccessMyLibrary.com

Article: Bee brains show just how smart they can be. - Australasian …  -  Oct 26, 2008
...contact K. Morita, Brain Research Institute, Dept. of Neurosurgery ... Rhabdomyosarcoma Therapy, Brain Research, Doxorubicin Hydrochloride ... ... Pay-Per-View - Australasian Business Intelligence - HighBeam Research

Doxorubicin; Cells respond differently to doxorubicin  -  Oct 25, 2005
Anthracycline, Anticancer Therapy, Breast Cancer, Breast Carcinoma, Cancer Therapy, Cytotoxic Activity, Doxorubicin Hydrochloride, Drug Accumulation, ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Cervical Cancer; Pegylated liposomal doxorubicin has limited activity...  -  Sep 26, 2006
Clinical Trials, Liposomal Delivery, Doxorubicin Hydrochloride, Gynecology, Liposomal Doxorubicin, Liposomes, Medical Device, Oncology, Women's Health. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Drug/Medical Device Report Kosan Biosciences Incorporated (KOSN)  -  Jun 21, 2008
Liposomal Doxorubicin Hydrochloride). -. Johnson & Johnson (JNJ) / Doxil (Doxorubicin HCl. Liposomal Injection). -. Celgene Corporation (CELG) / Revlimid ... $70.00 - Revere - Alacra Store

Doxorubicin; Cells respond differently to doxorubicin  -  Oct 25, 2005
Anthracycline, Anticancer Therapy, Breast Cancer, Breast Carcinoma, Cancer Therapy, Cytotoxic Activity, Doxorubicin Hydrochloride, Drug Accumulation, ... Pay-Per-View - Cancer Weekly - Factiva, from Dow Jones

Drug Delivery; Microemulsion stabilized by mixed surfactant is...  -  Oct 24, 2006
Keywords: Sao Paulo, Brazil, Biocompatibility, Biotechnology, Doxorubicin Hydrochloride, Drug Delivery, Medical Device, Microemulsion, Microtechnology, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Press Release: Ortho Biotech Files sNDA for DOXIL(R) for the Treatment...  -  Sep 8, 2008
DOXIL.com. IMPORTANT SAFETY ... Biotechnology Company, Breast Cancer, Breast Carcinoma ... Inc., Docetaxel, Doxil, Doxorubicin Hydrochloride ... ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: CAELYX(R) Delays Time to Disease Progression as …  -  Jun 3, 2007
...that showed maintenance chemotherapy with CAELYX(R) (pegylated liposomal doxorubicin hydrochloride) significantly prolonged time to progression (TTP) in ... Pay-Per-View - PR Newswire - HighBeam Research

University of Iowa; Doxorubicin increases hydrogen peroxide in PC3 …  -  Oct 26, 2005
Keywords: Iowa City, Iowa, United States, Aminotriazole, Amplex Red, Catalase, Doxorubicin, Doxorubicin Hydrochloride, Cancer Drugs, Enzymology, ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Press Release: About 60 Clinical Studies Regarding Schering-Plough's ...  -  May 30, 2008
Data will be presented on TEMODAR(R) (temozolomide) Capsules, CAELYX(R) (pegylated liposomal doxorubicin hydrochloride), INTRON(R) A (Interferon alfa-2b, ... Pay-Per-View - PR Newswire - HighBeam Research

Tiny Diamonds For Drug Delivery Mined By Nanoengineers  -  Oct 15, 2007
For their study, Ho and his team used living murine macrophage cells, human colorectal carcinoma cells and doxorubicin hydrochloride, a widely used ... Medical News Today - Medical News Today (press release)

Cancer Therapy; Doxorubicin modulates TA in Ewing sarcoma  -  Oct 4, 2005
Keywords: Munster, Germany, Apoptosis, Diagnosis, Diagnostics, Doxorubicin, Doxorubicin Hydrochloride, Drugs, Enzymology, Ewing Sarcoma, hTERT, Oncology, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Cancer Research; New findings from Canada, the People's Republic of …  -  Sep 5, 2006
Biotechnology, Dermal Fibroblast, Doxorubicin, Doxorubicin Hydrochloride, Gene Therapy, Oligonucleotide, Oncology, Pharmaceuticals, Synovial Sarcoma. ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

News Briefs: No to cancer drugs.(News) | Article from Liverpool Echo...  -  Aug 7, 2008
They are less likely to be prescribed topotecan and pegulated liposomal doxorubicin hydrochloride,both recommended. Liverpool Echo (Liverpool, England) ... Pay-Per-View - Liverpool Echo - HighBeam Research

Breast Cancer; No benefit found for doxorubicin/docetaxel vs....  -  Jun 28, 2005
Keywords: Lanark, Scotland, Breast Cancer, Cyclophosphamide, Docetaxel, Doxorubicin, Doxorubicin Hydrochloride, Anticancer Drugs, Therapy, Women's Health. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Abraxis BioScience Reports an Increase in Third Quarter Revenue of 19...  -  Nov 8, 2007
APP also launched Doxorubicin Hydrochloride Injection, the generic equivalent of Adriamycin([R]), which is owned by Bedford Laboratorie. Free with registration - Business Wire - AccessMyLibrary.com

Drug/Medical Device Report Kosan Biosciences Incorporated (KOSN)  -  Jun 21, 2008
Liposomal Doxorubicin Hydrochloride). -. Barr Pharmaceuticals, Inc. (BRL) / Thalidomide. -. Johnson & Johnson (JNJ) / Doxil (Doxorubicin HCl ... $70.00 - Revere Reports - Revere

Earns Schering Plough Pictures from September 6, 2006 | HighBeam …  -  Sep 6, 2006
DOXORUBICIN Schering-Plough Corp. has received European Union approval to market Caelyx (pegylated liposomal doxorubicin hydrochloride) as monotherapy for ... Pay-Per-View - AP Images - HighBeam Research

Chemotherapy; First-line doxorubicin and docetaxel deemed effective...  -  Dec 13, 2005
Cyclophosphamide, Docetaxel, Doxorubicin Hydrochloride, Cancer Drugs, Fluorouracil, Oncology, Pharmaceuticals, Cancer Therapy, Women's Health. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

CAELYX Delays Time To Metastatic Breast Cancer Progression  -  Jun 4, 2007
CAELYX is a long-circulating pegylated liposomal formulation of doxorubicin hydrochloride, a widely used cytotoxic agent. CAELYX is approved in the European ... emaxhealth.com

Article: Changes proposed for hydroxyurea labels.(Skin Disorders)(Brie...  -  Apr 1, 2006
...including HYDREA(R) (hydroxyurea) and RUBEX(R) (doxorubicin hydrochloride ... certain blood cell disorders associated with cancer chemotherapy. ... Pay-Per-View - Family Practice News - HighBeam Research

Pharmaceutical manufacturing: news in brief  -  Oct 19, 2007
The team used the chemotherapy drug doxorubicin hydrochloride. The study, published online by the journal Nano Letters, is the first to demonstrate the use ... In-PharmaTechnologist.com

Breast Cancer; TGF-beta signaling pathway impairment causes …  -  Sep 16, 2005
Keywords: Lviv, Ukraine, Breast Cancer, Breast Carcinoma, Cancer Therapy, Doxorubicin Hydrochloride, Drugs, Enzymes, Enzymology, Oncology, Proteins, ... Pay-Per-View - Angiogenesis Weekly - Factiva, from Dow Jones

Mining tiny diamonds for drug delivery  -  Nov 8, 2007
For their study, Ho and his team used living murine macrophage cells, human colorectal carcinoma cells, and doxorubicin hydrochloride, a widely used ... Nanowerk LLC

Nanoengineers mine tiny diamonds for drug delivery  -  Oct 12, 2007
For their study, Ho and his team used living murine macrophage cells, human colorectal carcinoma cells and doxorubicin hydrochloride, a widely used ... RxPG NEWS

Mining Tiny Diamonds for Drug Delivery, Drug Delivery, NCI Alliance...  -  Nov 11, 2007
For their study, Ho and his team used living murine macrophage cells, human colorectal carcinoma cells, and doxorubicin hydrochloride, a widely used ... nanotechwire.com

Minimize Chemotherapy-Induced Hand-Foot Syndrome  -  Aug 9, 2007
The new drug is a long-circulating formulation in which doxorubicin hydrochloride is encapsulated within pegylated liposomes. ... Medscape

Technology Research News  -  Jul 10, 2007
In the lab, nanodiamonds carry the anticancer drug doxorubicin hydrochloride into cancer cells and release it inside the cells. ... Technology Research News

Diamonds Against Cancer, TBC, Viruses  -  Nov 12, 2007
Ho's team made investigations in living mice macrophage cells and human colorectal carcinoma cells, using doxorubicin hydrochloride, a common chemotherapy ... Softpedia

Article: Anti-Smoking Pill May Help Curb Drinking - AP Online |...  -  Jul 10, 2007
Doxorubicin Hydrochloride, Drug Development, Drug Resistance, Drugs, Etoposide, Gynecology ... Health, Hong Kong Polytechnic University. ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Article: Anti-Smoking Pill May Help Curb Drinking - AP Online |...  -  Jul 10, 2007
Doxorubicin Hydrochloride, Drug Development, Drug Resistance, Drugs, Etoposide, Gynecology ... Health, Hong Kong Polytechnic University. ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Breast Cancer; Early response to neoadjuvant iFAC predicted favorable...  -  Jan 3, 2006
Keywords: Seoul, South Korea, Adriamycin, Breast Carcinoma, Cyclophosphamide, Doxorubicin Hydrochloride, Cancer Drugs, Locally Advanced Breast Cancer, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Chemotherapy; Cardiac toxicity in breast cancer treated with doxorubic...  -  Nov 22, 2005
Keywords: Brussels, Belgium, Breast Carcinoma, Cardiac Toxicity, Cardiology, Chemotherapy, Doxorubicin, Doxorubicin Hydrochloride, Endocrinology, Hormones, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Chemotherapy; Efficacy of fluorouracil, doxorubicin, and cisplatin/ …  -  Oct 25, 2005
Keywords: Niigata, Japan, Cisplatin, Doxorubicin Hydrochloride, Cancer Drugs, Efficacy, Esophageal Cancer, Esophageal Carcinoma, Esophagectomy, FAP/N, ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Chemotherapy; Efficacy of fluorouracil, doxorubicin, and cisplatin/ …  -  Oct 24, 2005
Keywords: Niigata, Japan, Cisplatin, Doxorubicin Hydrochloride, Cancer Drugs, Efficacy, Esophageal Cancer, Esophageal Carcinoma, Esophagectomy, FAP/N, ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Angiosarcoma; Paclitaxel and pegylated-liposomal doxorubicin are both...  -  Sep 16, 2005
Keywords: Minneapolis, Minnesota, United States, Angiosarcoma, Bedford Laboratories, Chemotherapy, Doxorubicin Hydrochloride, Kaposi Sarcoma, Liposomes, ... Pay-Per-View - Angiogenesis Weekly - Factiva, from Dow Jones

Chemotherapy; Efficacy of fluorouracil, doxorubicin, and cisplatin/ …  -  Oct 29, 2005
Keywords: Niigata, Japan, Cisplatin, Doxorubicin Hydrochloride, Cancer Drugs, Efficacy, Esophageal Cancer, Esophageal Carcinoma, Esophagectomy, FAP/N, ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Niigata University; Efficacy of fluorouracil, doxorubicin, and...  -  Oct 26, 2005
Keywords: Niigata, Japan, Cisplatin, Doxorubicin Hydrochloride, Cancer Drugs, Efficacy, Esophageal Cancer, Esophageal Carcinoma, Esophagectomy, FAP/N, ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Chemotherapy; Efficacy of fluorouracil, doxorubicin, and cisplatin/ …  -  Oct 28, 2005
Keywords: Niigata, Japan, Cisplatin, Doxorubicin Hydrochloride, Cancer Drugs, Efficacy, Esophageal Cancer, Esophageal Carcinoma, Esophagectomy, FAP/N, ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Chemotherapy; Efficacy of fluorouracil, doxorubicin, and cisplatin/ …  -  Oct 25, 2005
Keywords: Niigata, Japan, Cisplatin, Doxorubicin Hydrochloride, Cancer Drugs, Efficacy, Esophageal Cancer, Esophageal Carcinoma, Esophagectomy, FAP/N, ... Pay-Per-View - Cancer Weekly - Factiva, from Dow Jones

Angiosarcoma; Paclitaxel and pegylated-liposomal doxorubicin are both...  -  Sep 12, 2005
Keywords: Minneapolis, Minnesota, United States, Angiosarcoma, Bedford Laboratories, Chemotherapy, Doxorubicin Hydrochloride, Kaposi Sarcoma, Liposomes, ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

Chemotherapy; Efficacy of fluorouracil, doxorubicin, and cisplatin/ …  -  Oct 30, 2005
Keywords: Niigata, Japan, Cisplatin, Doxorubicin Hydrochloride, Cancer Drugs, Efficacy, Esophageal Cancer, Esophageal Carcinoma, Esophagectomy, FAP/N, ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Chemotherapy; Etoposide, doxorubicin and cisplatin plus mitotane used...  -  Dec 20, 2005
Cisplatin, Cortical Cancer, Cortical Carcinoma, Doxorubicin Hydrochloride, Cancer Drugs, Endocrinology, Etoposide, Mitotane, Oncology, Cancer Therapy. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Breast Cancer; Neoadjuvant docetaxel combined with adjuvant …  -  Oct 11, 2005
Keywords: Bethesda, Maryland, United States, Breast Carcinoma, Cyclophosphamide, Doxorubicin Hydrochloride, Endocrinology, Hormones, Neoadjuvant Docetaxel, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Cancer Treatment; New findings from France, the People's Republic of ...  -  Sep 5, 2006
Keywords: Toronto, Ontario, Canada, Cervical Cancer, Carboplatin, Doxorubicin Hydrochloride, Pegylated Liposomal Doxorubicin, Uterine Cancer. ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Press Release: Ortho Biotech Seeks FDA Approval for DOXIL(R) in …  -  Jan 22, 2007
DOXIL(R) is indicated for first-line treatment ... Retroviruses and Opportunistic Infections. DOXIl is a formulation of doxorubicin hydrochloride ... ... Pay-Per-View - PR Newswire - HighBeam Research

Federal Register 2005 - 70 FR 62126 Oncologic Drugs Advisory …  -  Oct 28, 2005
The committee will discuss phase IV commitments of: (1) New drug application (NDA) 50-718, DOXIL (doxorubicin hydrochloride liposome injection, ... Pay-Per-View - Federal Register 2005 - Loislaw

Chemicals, raw materials & specialties.(DIPHENYLACETYLENE-1- …  -  Jan 1, 2007
DOXORUBICIN HYDROCHLORIDE ** SPECTRUM CHEMICAL MFG. CORP. 877-656-5788, ask for catalog www.spectrumchemical.com DOXYCYCLINE Alfa Chem Hovione ... $4.95 - Chemical Week - ECNext

Endometrial Cancer; Worse endometrial cancer survival predicted by …  -  Aug 29, 2006
Keywords: New York, New York, United States, Paclitaxel, AUC, Advanced Endometrial Cancer, Cisplatin, Doxorubicin Hydrochloride, Cancer Drugs, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Cancer Gene Therapy; Osteosarcoma treated by adenovirus-mediated …  -  May 17, 2006
Keywords: Toronto, Ontario, Canada, Adenovirus, Biotechnology, Cancer Gene Therapy, Child Cancer, Cisplatin, Doxorubicin Hydrochloride, Drug Development, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Breast Cancer; Changes in gene expression associated with response to...  -  Jul 19, 2005
Keywords: Amsterdam, Netherlands, Bedford, Biotechnology, Breast Cancer, Breast Carcinoma, Chemotherapies, Doxorubicin, Doxorubicin Hydrochloride, Drugs, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Breast Cancer; Neoadjuvant chemotherapy evaluated in stage III breast...  -  Sep 13, 2005
Keywords: Shreveport, Louisiana, United States, Breast Cancer, Breast Carcinoma, Cisplatin, Doxorubicin Hydrochloride, Oncology, Pharmaceuticals, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Cancer Therapy; Molecular determinants of reduced cardiotoxicity of …  -  Jun 7, 2006
Keywords: Chieti, Italy, Anticancer Therapy, Cancer Therapy, Cardiotoxicity, Cardiology, Doxorubicin Hydrochloride, Cancer Drugs, Endocrinology, Epirubicin, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Cancer Therapy; Topoisomerase II inhibitors enhanced by using …  -  Mar 7, 2006
Keywords: Jackson, Mississippi, United States, C-Myc Topoisomerase II Inhibitor, Chemotherapy, Combination Therapy, Doxorubicin, Doxorubicin Hydrochloride, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Drug Safety; Paclitaxel and docetaxel stimulate doxorubicinol...  -  Aug 29, 2006
Keywords: Chieti, Italy, Cardiology, Cardiotoxicity, Chemotherapy, Docetaxel, Doxorubicin Hydrochloride, Endocrinology, Heart, Metabolism, Metabolite, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Ovarian Cancer Therapy; Scientists at Massachusetts General Hospital,...  -  Dec 25, 2006
Keywords: United States, Boston, Ovarian Cancer Therapy, Cisplatin, Clinical Trial, Doxorubicin Hydrochloride, Drug Resistance, Drugs, Efficacy Trials, ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones

Drug Delivery; Local delivery of IL-2 and adriamycin has synergistic ...  -  Nov 29, 2005
Adriamycin, Biodegradable Polymer, Biotechnology, Brain Cancer, Brain Carcinoma, Brain Tumor, Cytokine, Doxorubicin Hydrochloride, Drug Delivery, IL-2, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Press Release: Newly-Published Study Shows CAELYX(R) Plus …  -  Feb 16, 2007
...doxorubicin hydrochloride), in combination with carboplatin, to be highly effective in patients with ovarian cancer which had been previously treated. ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Federal Register 2005 - 70 FR 60094 Oncologic Drugs Advisory …  -  Oct 14, 2005
The committee will discuss phase IV commitments of: (1) new drug application (NDA) 50-718, DOXIL (doxorubicin hydrochloride liposome injection, ... Pay-Per-View - Federal Register 2005 - Loislaw

Cancer Therapy; Melatonin/adriamycin combination enhanced antitumor …  -  Dec 6, 2005
Cardiology, Cardiotoxicity, Cardiovascular, Doxorubicin Hydrochloride, Fragmentation, Melatonin, Oncology, Pharmaceuticals, Side Effect, Women's Health. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Drug Resistance; Researchers from University of Washington detail new...  -  Jan 1, 2007
Keywords: United States, Seattle, Doxorubicin Hydrochloride, Drug Development, Drug Resistance, Drugs, Paclitaxel, Pharmaceutical Sciences, Pharmaceuticals, ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

Press Release: Revised NICE Guidance on Alzheimer's Disease (AD) …  -  Sep 7, 2007
Notes to Editors: The new NICE guidance recommends the use of pegylated liposomal doxorubicin hydrochloride ... PR Newswire Europe ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Chemotherapy; Cisplatin plus epirubicin deemed effective regimen in …  -  Nov 22, 2005
Keywords: Brussels, Belgium, Alopecia, Chemotherapy, Cisplatin, Doxorubicin Hydrochloride, Epirubicin, Lung Cancer, Lung Carcinoma, Malignant Mesothelioma, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Cancer drugs plea.(News) | Article from Liverpool Echo (Liverpool, …  -  Oct 11, 2005
They are less likely to be prescribed topotecan and pegulated liposomal doxorubicin hydrochloride,both recommended. Liverpool Echo (Liverpool, England) ... Pay-Per-View - Liverpool Echo - HighBeam Research

Article: Anti-Smoking Pill May Help Curb Drinking - AP Online |...  -  Jul 10, 2007
Doxorubicin Hydrochloride, Drug Development, Drug Resistance, Drugs, Etoposide, Gynecology ... Health, Hong Kong Polytechnic University. ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

University of Michigan, US Research by University of Michigan, US, …  -  Jan 1, 2007
Keywords: Ann Arbor, Michigan, United States, Chest Computed Tomography, Doxorubicin Hydrochloride, Cancer Drugs, Lung Metastasis, Metastatic Disease, ... Pay-Per-View - Biotech Business Week - Factiva, from Dow Jones

[æ¯?日阅读]英文è?¯å“?说明书的写法  -  Sep 8, 2006
Sterile pyrogen-free, orange red, freeze-dried powder in vials containing 10mg and 50mg of doxorubicin hydrochloride with lactose. ... ��

Brand Names/Synonyms:
Doxorubicin Hydrochloride is also known by the following brand names and/or synonymsADM; Adriablastin; Adriamycin; Adriamycin Pfs; Adriamycin Rdf; Adriamycin Semiquinone; Adriblastin; Adriblastina; CCRIS 739; Caelyx;; DM2; Doxil; Doxo; Doxorubicin; Doxorubicin Hcl; Doxorubicin Hydrochloride; Doxorubicin [Usan:Ban:Inn]; Doxorubicina [Inn-Spanish]; Doxorubicine [Inn-French]; Doxorubicinum [Inn-Latin]; FI 106; FI-106; HSDB 3070; Rdf Rubex; Rubex

Drug Category:
Doxorubicin Hydrochloride is categorized under the following by the FDA: Antibiotics; Antineoplastic Agents; ATC:L01DB01

Dosage Forms:
POWDER FOR SOLUTION

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
10-(4-amino-5-hydroxy-6-methyl-oxan-2-yl)oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione





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