EMEND

This page contains recent news articles, when available, and an overview of EMEND but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

EMEND
(when available)

Pharmacology and use:
Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy. Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. Aprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting (CI NV). For the prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy, including high-dose cisplatin (in combination with other antiemetic agents).

Mechanism Of Action:
Aprepitant has been shown in animal models to inhibit emesis induced by cytotoxic chemotherapeutic agents, such as cisplatin, via central actions. Animal and human Positron Emission Tomography (PET) studies with Aprepitant have shown that it crosses the blood brain barrier and occupies brain NK1 receptors. Animal and human studies show that Aprepitant augments the antiemetic activity of the 5-HT3-receptor antagonist ondansetron and the corticosteroid ethasone and inhibits both the acute and delayed phases of cisplatin induced emesis.

News Articles on Aprepitant

Elan Corp: First Japanese OK Of Pdt Using Its NanoCrystal  -  ‎Dec 13, 2009‎
...-EMEND, which was developed by a subsidiary of Merck & Co Inc., Whitehouse Station, NJ, US and licensed to Ono Pharmaceuticals Co., for the Japanese market, ... Wall Street Journal

ADR Report: ADRs Close Up With Oil, Solar Companies Higher  -  ‎Dec 14, 2009‎
...(ELN), said Monday that the Japanese Ministry of Health, Labour and Welfare has approved EMEND, or aprepitant, for the treatment of cancer ... Wall Street Journal

ISEQ creeps into positive territory  -  ‎Dec 15, 2009‎
Elan announced that the Japanese Ministry of Health has approved Merck's drug Emend for the treatment of cancer-chemotherapy induced nausea and vomiting. ... Irish Independent

日本劳动厚生çœ?批准EMEND上市  -  ‎Dec 14, 2009‎
Elan (ELN)å­?å…¬å?¸Elan Drug Technologies宣布,日本劳动厚生çœ?批准EMEND上市,治疗癌症化疗引起的æ?¶å¿ƒä¸Žå‘•å??症状。 å…?责声明:本文仅代表作者个人观点,与凤凰网无关。 ... 凤凰网

The Other Four-Letter "F" Word At Funk Fest  -  ‎Nov 11, 2009‎
What about if you emend it to "frigging"? Okay, but isn't that a bit silly? Because in this context "frigging" is doing exactly the same thing as "fucking," ... LBPOST.com

Schering-Plough and Merck & Co., Inc.; Analysis of Agreement Containing ...  -  ‎Nov 10, 2009‎
Merck introduced the first NK1 receptor antagonist, Emend(R) (aprepitant), in 2003, and remains the only firm in the United States with an approved drug in ... Trading Markets (press release)

Stiffer fines for people who do not wear seatbelts  -  ‎Nov 1, 2009‎
...it is obvious that the fines system has failed drastically. we should try and emend this by educational campains and not by increasing fines. ... Times of Malta

Merck Announces Third-Quarter 2009 Financial Results  -  ‎Oct 22, 2009‎
CANCIDAS, COSOPT, CRIXIVAN, EMEND, FOSAMAX, INVANZ, ISENTRESS, MAXALT, PRIMAXIN, PROPECIA, PROSCAR, STOCRIN, TIMOPTIC/TIMOPTIC XE, TREDAPTIVE, TRUSOPT, ... Reuters

US FTC Clears Merck-Schering Deal, With Conditions  -  ‎Oct 29, 2009‎
Merck's Emend is the only such drug approved for human use to treat nausea from chemotherapy and surgery, but Schering-Plough was in the process of ... Capital.gr (press release)

默沙东收购先ç?µè‘†é›… 美国è?”邦贸易委员会正å¼?批准  -  ‎Oct 30, 2009‎
...默克公å?¸çš„Emend是唯一被批准的用于治疗化疗和手术æ?¶å¿ƒçš„人类è?¯å“?,但先ç?µè‘†é›…的类似è?¯å“?rolapitant正在审批的过程中。 è?”邦贸易委员会表示,先ç?µè‘†é›…必须在å?ˆå¹¶å®Œæˆ?10 ... 生物谷

Mnnesvärd kväll  -  ‎Nov 8, 2009‎
På morgonen skulle jag också ta illamående pillret Emend och sen hade jag fått mera piller mot illamåendet det heter Pimperan som jag fått både som ... Upsala Nya Tidning

æ—¥ '서바릭스' 'ìž?누비아' 등 신약 대거 승ì?¸  -  ‎Oct 20, 2009‎
...ì?´ 외ì—?ë?„ 오노약품ì?˜ 경구 2형 당뇨병 치료제 '글랙티브'(Glactiv, sitagliptin phosphate hydrate)와 ì„ íƒ?ì ? 뉴로퀴닌1(NK1) 수용체 길항형 제토제 'ì?´ë©˜ë“œ'(Emend, ... 디지틀보사

FDA Approves EMEND® (aprepitant), in Combination with Other …  -  Jan 11, 2006
WHITEHOUSE STATION, NJ, Jan. 11, 2006 - Merck & Co., Inc. announced today that the Food and Drug Administration (FDA) has approved EMEND® (aprepitant) for ... biotech-intelligence.com

Merck says FDA seeks more data on Emend injection  -  May 11, 2007
CHICAGO, May 11 (Reuters) - Merck & Co. (MRK.N) on Friday said US regulators want more data on its experimental injectable drug for nausea caused by ... Reuters

… Patients Showed Regimen Including EMEND-R- -Aprepitant- Prevented ...  -  Apr 18, 2005
The results of an investigational study evaluating the effect of an antiemetic regimen including EMEND(R) in the prevention of nausea and vomiting after ... RedOrbit

FDA Approves EMEND (aprepitant), Merck's Antiemetic Therapy, For The ...  -  Jul 17, 2006
Merck & Co., Inc. announced today that the US Food and Drug Administration (FDA) has approved EMEND (aprepitant) for the prevention of postoperative nausea ... Medical News Today - Medical News Today (press release)

FDA Approves Intravenous form of Merck and Co., Inc. (MRK) Nausea …  -  Jan 30, 2008
EMEND for Injection is an intravenous prodrug of the oral formulation of EMEND® ... EMEND for Injection is approved for use in combination with other ... Lifescience-online

EMEND® (aprepitant) Helps Prevent Nausea/Vomiting for Breast Cancer …  -  Apr 21, 2005
The results of an investigational study evaluating the effect of an antiemetic regimen including EMEND® in the prevention of nausea and vomiting after ... i-newswire.com

An Overweight Tabby in London in 'Garfield: A Tale of Two Kitties'  -  Jun 16, 2006
To borrow and slightly emend the words of Shakespeare: That cat will mew, but this dog will have the day. "Garfield: A Tale of Two Kitties" is rated PG ... New York Times

Mintz. acting chairman of emend and serve everyone  -  Mar 18, 2008
A move to settle a railroad disp on the former Charleston Na v val Base has stopped at a lawyer crossing — for the moment. The Charleston Naval Complex ... Post And Courier - Google News Archive

FDA OKs Merck & Co's Emend in combination.(Brief Article)  -  Jan 16, 2006
US drug major Merck & Co says that the Food and Drug Administration has approved Emend (aprepitant) for use with other antiemetic medicines for the ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Colorectal Cancer,Metastatic or Recurrent - Medications  -  Oct 1, 2008
Aprepitant (Emend), which is used in combination with ondansetron and dexamethasone as part of a 3-day program. Serotonin antagonists, such as ondansetron ... WebMD

Merck Receives Approvable Letter for Emend Injection  -  May 15, 2007
The FDA has issued an approvable letter for Merck's NDA for Emend (fosaprepitant dimeglumine) injection (MK-0517) an investigational intravenous therapy for ... Facts and Comparisons

Addition of Emend to therapy reduces CNV.(Brief Article)  -  May 30, 2005
Results of a new study, presented at the American Society of Clinical Oncology annual meeting in Orlando, Florida, earlier this month, demonstrate that a ... $4.95 - Pharma Marketletter - ECNext

Emend.(NEW & APPROVED)(Drug overview)  -  Oct 1, 2006
A substance P/neurokinin 1 (N[K.sub.1]) receptor antagonist approved for preventing postoperative nausea and vomiting. Approved in 2003 for preventing ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Plavix, emend.(New & Approved)  -  Nov 1, 2006
This antiplatelet agent has a newly approved claim for reducing the rate of death from any cause and the rate of a combined end point of death, reinfarction ... Free with registration - Skin & Allergy News - AccessMyLibrary.com

FDA clears Merck & Co's Emend Injection for CINV.  -  Feb 4, 2008
US drug major Merck & Co says that the Food and Drug Administration has approved Emend (fosaprepitant dimeglumine) for Injection, a new intravenous therapy ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Probably, It's Just Fine To Use Likely .  -  Jul 10, 2005
...court for an order distinguishing "amend" from "emend." No problem. To amend is to change. To emend is to correct. This will be on the quiz. Court stands . Eugene Register-Guard - Google News Archive

Business News in Brief  -  Jul 12, 2006
Inc. won US approval of its nausea treatment Emend to prevent vomiting in ... Emend generated $87 million in sales last year for the Whitehouse Station, NJ, ... $2.95 - Philadelphia Inquirer - NewsBank

FDA asks for more data on Emend injection.  -  May 21, 2007
FDA asks for more data on Emend injection. US drug major Merck & Co has received an "approvable" letter from the Food and Drug Administration for the New ... $9.94 - Pharma Marketletter - Alacra Store

CMS Expands Medicare Coverage to Include Merck's Emend  -  Apr 7, 2005
The Centers for Medicare & Medicaid Services (CMS) has expanded its coverage of Medicare Part B drugs to include Merck's oral, anti-nausea treatment Emend. ... Pay-Per-View - Drug Industry Daily - Factiva, from Dow Jones

Article: Plavix, Emend.(drugs for myocardial infarction and digestive...  -  Oct 15, 2006
Plavix, Emend.(drugs for myocardial infarction and digestive symptoms)(Disease/Disorder overview) ... find Family Practice News articles. Pay-Per-View - Family Practice News - HighBeam Research

Merck to seek FDA approval for new weight loss and cholesterol drugs  -  Dec 12, 2007
Merck is also expecting the approval of two more drugs next year: Cordaptive and the injectable treatment Emend. Cordaptive is still an experimental drug ... Money Times - The Money Times

Medicare Part B Coverage Expands to Include Merck's Emend  -  Apr 14, 2005
The Centers for Medicare & Medicaid Services (CMS) has expanded its coverage of Medicare Part B drugs to include Merck's oral, antinausea treatment Emend. ... Pay-Per-View - FDAnews Drug Daily Bulletin - Factiva, from Dow Jones

Emend clearance.(RXs)(FDA approves Merck & Company Inc.'s Emend)( …  -  Mar 17, 2008
Emend clearance.(RXs)(FDA approves Merck & Company Inc.'s Emend)(Brief article) ... find Chain Drug Review articles. The FDA has approved an intravenous ... Pay-Per-View - Chain Drug Review - HighBeam Research

Emend for Injection.  -  Jul 1, 2007
Fosaprepitant (Emend for Injection, Merck) for the treatment of chemotherapy-induced nausea and vomiting (CINV) Copyright 2007 Advanstar Communications, ... $9.94 - Formulary - Alacra Store

Emend for Injection.(Approvable designations)(from Merck & Company …  -  Jul 1, 2007
Fosaprepitant (Emend for Injection, Merck) for the treatment of chemotherapy-induced nausea and vomiting (CINV) $4.95 - Formulary - ECNext

Emend clearance.  -  Mar 17, 2008
Emend clearance. The FDA has approved an intravenous form of Merck & Co.'s Emend, a nausea drug indicated for patients undergoing chemotherapy. ... $9.94 - Chain Drug Review - Alacra Store

FDA Approves EMEND(R) (aprepitant), Merck's Antiemetic Therapy and …  -  Jul 12, 2006
City of Industry, CA - Pharmaceuticals Instruments industry alert provided by US Equity News. Merck & Co., Inc. (NYSE:MRK) announced recently that the US ... Free with registration - M2 Presswire - AccessMyLibrary.com

Emend.  -  Mar 1, 2008
Fosaprepitant (Emend, Merck) for intravenous (IV) injection was approved for use in combination with other antiemetic agents for the prevention of acute and ... $9.94 - Formulary - Alacra Store

Plavix, Emend.(drugs for myocardial infarction and digestive symptoms)...  -  Oct 15, 2006
This antiplatelet agent has a newly approved claim for reducing the rate of death from any cause and the rate of a combined end point of death, reinfarction ... Pay-Per-View - Family Practice News - Factiva, from Dow Jones

China's cabinet stresses resources conservation  -  Jun 23, 2005
Meanwhile, it also called for deepening reforms so as to perfect policies on energy-saving industries, formulate and emend relevant laws and regulations. ... People's Daily Online

Product news from the 05/15/07 news brief  -  May 15, 2007
The FDA told Merck it will need to provide additional data to the agency before it can approve Emend, an experimental injectable drug for nausea caused by ... Medical Marketing & Media - Medical Marketing and Media

… : Celera moves to cut staff; FDA expands Emend use; FDA approves …  -  Jan 10, 2006
...> The FDA has expanded its approval for Merck's nausea drug Emend to include cancer patients undergoing chemotherapy. Report ... FierceBiotech

FDA Approvals: Emend, Gemzar, Avastin  -  Jul 21, 2006
July 21, 2006 — The US Food and Drug Administration (FDA) has approved aprepitant capsules for use in preventing postoperative nausea and vomiting; ... Medscape

Emend.(News from the FDA)(Brief article)  -  Mar 1, 2006
Emend (aprepitant), an antinausea drug used to control vomiting in patients undergoing chemotherapy, has received an expanded indication for use with other ... Free with registration - Patient Care for the Nurse Practitioner - AccessMyLibrary.com

emend | Article from The Oxford American Writers Thesaurus | HighBeam...  -  Jul 12, 2006
...emend ... find The Oxford American Writers Thesaurus articles. emend. Pay-Per-View - Oxford American Writers Thesaurus - HighBeam Research

Article: Prevent chemotherapy nausea.(Emend approval for preventing …  -  Apr 1, 2006
Prevent chemotherapy nausea.(Emend approval for preventing nausea ) ... find Internal Medicine News articles. Emend (aprepitant) has been approved for use ... Pay-Per-View - Internal Medicine News - HighBeam Research

Article: emend - The Oxford Pocket Thesaurus of Current English | …  -  Jul 12, 2006
...emend ... find The Oxford Pocket Thesaurus of Current English articles. emend. Pay-Per-View - Oxford Pocket Thesaurus of Current... - HighBeam Research

Emend.(NEW INDICATIONS)(Brief article)  -  Aug 21, 2006
Emend (aprepitant), from Merck & Co., Whitehouse Station, NJ, (908) 423-1000, has a new indication: prevention of postoperative nausea and vomiting. $4.95 - Drug Topics - ECNext

Emend.  -  Aug 21, 2006
Emend (aprepitant), from Merck & Co., Whitehouse Station, N.J., (908) 423-1000, ... Emend was approved earlier for the prevention of nausea and vomiting ... $9.94 - Drug Topics - Alacra Store

Press Release: FDA approves EMEND(R), in combination with other …  -  Jan 17, 2006
FDA approves EMEND(R), in combination with other antiemetics and Pfizer invites public to listen to webcast of January 19 conference call with analysts. Pay-Per-View - M2 Presswire - HighBeam Research

默克制è?¯ï¼šEmendå?¯å‡?少化疗患者æ?¶å¿ƒå??应  -  Apr 19, 2005
...ã€?MarketWatch纽约4月19日讯】默克制è?¯(MRK)周一收盘å?Žè¡¨ç¤ºï¼Œä¸€é¡¹è°ƒæŸ¥æ€§ç ”究结果显示, 如果乳癌患者在接å?—化疗å?Žä½¿ç”¨åŒ…括Emendè?¯ç‰©çš„疗法å?¯å‡?å°‘æ?¶å¿ƒä¸Žå‘•å??å??应。 ... 新浪网

emend | Definition of emend | HighBeam.com: Online Dictionary  -  Jul 12, 2006
Find out what emend means: The Oxford American College Dictionary has the definition of emend. Research related newspaper, magazine, and journal articles at ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

Emend.  -  Feb 1, 2006
Aprepitant (Emend, Merck) was approved to be used in combination with other antiemetic drugs to prevent nausea and vomiting associated with moderately ... $9.94 - Formulary - Alacra Store

Press Release: Oncologists Rank Aloxi's Marketing Message Most …  -  Dec 4, 2008
Merck's Emend Unable to Secure Top-of-Mind Position with U.S. Physicians, ... Emend scored low in terms of brand recognition with less than 20 percent of ... Pay-Per-View - PR Newswire - HighBeam Research

::: ê±´ê°•ì?´ ë³´ì?´ëŠ” 대한민국 대표 ì?˜ë£Œì‹ ë¬¸ 메디컬투ë?°ì?´ :::  -  Apr 2, 2007
...한국엠�스디㈜는 항구토제 �멘드(EMEND, 성분명 아프레피탄트aprepitant) 80mg 캡� 과 125mg 캡�� 대한 급여 �한 금액 고시(보건복지부 고시 제2007-24호) 가 4월 ... 메디컬투��

FDA approves intravenous form of Merck nausea drug  -  Jan 29, 2008
N) said on Tuesday that US health regulators approved a new intravenous form of its anti-nausea drug Emend for patients undergoing chemotherapy. ... Reuters

默克制è?¯Emendè?¯ç‰©èŽ·FDA许å?¯  -  Jul 12, 2006
...�MarketWatch纽约7月11日讯】周二盘�,默克制�(Merck & Co. Inc.) (MRK)宣布,该 公�已�收到美国食�与�物管�局对其Emend�物的许�,这��物用于治疗手术�的 ... 新浪网

â–’ 메디게ì?´íŠ¸ë‰´ìŠ¤ - 대한민국 ì?˜ì‚¬ê°€ 가장 ë§Žì?´ 보는 ì?˜ë£Œì „문 ì?¸í„°ë„·...  -  Feb 21, 2008
...등 4개기관 △�아제약 '제니낙스정':서울대 △글�소스미스��� 'GSK239512정': 서울아산 등 2개 기관 △한국엠�스디 'EMEND IV':성빈센트 등 6개 기관 등�다. ... 메디게�트뉴스

NJ BRIEFS | Article from The Record (Bergen County, NJ) | HighBeam …  -  Jan 12, 2006
Emend had been previously approved by the Food and Drug Administration for ... Emend can now be taken by patients undergoing chemotherapy with a lower ... Pay-Per-View - The Record - HighBeam Research

Merck & Co. erhält FDA-Zulassung für Emend  -  Jan 11, 2006
Der amerikanische Pharmakonzern Merck & Co. Inc. (ISIN US5893311077 / WKN 851719) hat von der Gesundheitsbehörde FDA eine Zulassung für das Medikament Emend ... AktienCheck

Press Release: Genzyme names new Head of Product Development for …  -  Jan 13, 2006
Genzyme names new Head of Product Development for Campath and Merck gets FDA OK for widened use of emend. from M2 Presswire. Highbeam Research – FREE Trial. Pay-Per-View - M2 Presswire - HighBeam Research

Article: Anti-alcoholism injection OK'd.(Slants & Trends) - Drug...  -  Apr 27, 2006
ILLUSTRATION OMITTED] An injectable form of Emend (fosaprepitant ... Emend for injection is an IV prodrug of the oral formulation of Emend (aprepitant) ... Pay-Per-View - Drug Detection Report - HighBeam Research

Wall Street-Schluss: Dow Jones erklimmt Viereinhalb-Jahres-Hoch  -  Jan 11, 2006
Inc. (ISIN US5893311077 / WKN 851719) hat von der Gesundheitsbehörde FDA eine Zulassung für das Medikament Emend erhalten. Wie der Konzern am Mittwoch ... AktienCheck

MPF cobra entrega de remédio para quimioterapia  -  Jan 24, 2008
O procurador observa que a imprensa já noticiou a recusa das operadoras em fornecer o Emend, lesando os interesses dos usuários. ... Terra Brasil

Stocks to Watch: Agilent, Amgen and Merck  -  May 13, 2007
Merck (MRK) said it has received an approvable letter from the Food and Drug Administration for the company's new drug application for Emend, ... FOXNews

CytoDyn annual meeting set and Johnson & Johnson statement …  -  Jan 18, 2006
...(NYSE:MRK) said Wednesday that the Food and Drug Administration approved its nausea treatment Emend for cancer patients who are undergoing chemotherapy. ... Free with registration - M2 Presswire - AccessMyLibrary.com

Merck 2006 Annual Business Briefing - Part 2.  -  Dec 12, 2006
MK-0517 is a prodrug of aprepitant the active ingredient in EMEND. ... As you know, we initially registered EMEND in oral therapy for the prevention of ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

What goes around comes around in drug discovery  -  Feb 23, 2006
We were drawn to this statement since your story focuses on Merck's anti-nausea drug Emend, without pointing out that Emend itself could be considered a ... Nature.com

Merck to seek approval of cholesterol, weight loss drugs - Dec. 11,...  -  Dec 11, 2007
Cordaptive is experimental, but Emend is already available in a capsule form. Merck Chief Executive Richard Clark said the company's growth has been driven ... CNNMoney.com

… for Campath and Merck gets FDA OK for widened use of emend.  -  Jan 13, 2006
...(NYSE:MRK) said Wednesday that the Food and Drug Administration approved its nausea treatment Emend for cancer patients who are undergoing chemotherapy. ... $4.95 - M2 Presswire - ECNext

Serotonin antagonists (5-HT3 receptor antagonists)  -  Aug 31, 2007
They are more effective when they are given with other medicines, such as dexamethasone and aprepitant (Emend), if used for nausea or vomiting caused by ... WebMD

'her .  -  Jul 9, 2005
Gregory Saenz of Redlands, Calif., petitions the court for an order distinguishing "amend" from "emend." No problem, To amend is to change. To emend is to ... Free-Lance Star - Google News Archive

Nausea? There's No Need to Suffer in Silence  -  Oct 24, 2006
Emend may be combined with another drug when chemotherapy, for example high-dosage cisplatin, is highly likely to cause nausea and vomiting. ... New York Times

Pipeline Keeps Merck Hopeful  -  Dec 11, 2006
A decision should come in the second quarter for Emend IV for ... The drug is an intravenous version of the Emend pill that Merck introduced in 2003. ... TheStreet.com - TheStreet.com (subscription)

FDA approves nausea drug for cancer patients  -  Jan 13, 2006
Emend, made by Merck, was shown in a study of breast cancer patients to significantly reduce the chances for nausea and vomiting when added to a regimen of ... Advocate.com

Cancer's other battle: Families learn to deal with range of side...  -  May 30, 2008
Emend is expensive, however; at our local pharmacy, a three-day pack costs $418. We're very lucky insurance covers it. There's another effective treatment ... $2.95 - Salt Lake Tribune, The - NewsBank

United States: Nanotech Meets the FDA: A Success Story About the...  -  May 27, 2005
Commercially marketed as Emend®, aprepitant is the first FDA approved drug for ... With the exception of Emend®, a new chemical entity, Elan's licensees and ... Mondaq News Alerts - Mondaq News Alerts (Registration)

Midday stocks to watch, VCYI-SIRI,MRK-LSV.  -  Jan 12, 2006
Merck Approves EMEND, in combination with other antiemetics (MRK) 33.33 : Co announces the FDA has approved EMEND (aprepitant) for use with other antiemetic ... $4.95 - M2 Presswire - ECNext

Medicare to Cover Merck Anti-Nausea Drug  -  Apr 5, 2005
Inc."s drug, Emend, when used with two other drugs to treat nausea and vomiting in cancer ... Emend, also known as aprepitant, will be covered when added to ... Cancerpage.com

Elan Announces the Johnson & Johnson Pharmaceutical Research …  -  Oct 29, 2007
Rapamune[R] is a registered trademark owned by Wyeth Pharmaceuticals. Emend[R] is a registered trademark owned by Merck & Co., Inc. Free with registration - Business Wire - AccessMyLibrary.com

Health Tips From UPI: April 25, 2005  -  Apr 25, 2005
TREATMENT MAY EASE CHEMOTHERAPY SIDE EFFECTS A study suggests a regimen including Emend may help prevent chemotherapy-related nausea and vomiting in breast ... RedOrbit

Podcast: Managing nausea and vomiting during chemotherapy  -  Sep 12, 2008
The one that's around now is called aprepitant, or the brand name for that is Emend. So for example if we have people with grade 4 nausea and vomiting ... MayoClinic.com

Communications.(Letter to the Editor)  -  Mar 1, 2005
As with all responsible editions, such emendations are reported and discussed in a critical apparatus--as are refusals to emend, and variants in relevant ... Free with registration - Notes - AccessMyLibrary.com

FDA Weighs Risk of Vioxx Successor Drug | Article from AP Online | …  -  Apr 10, 2007
Corp., was approved by the Food and Drug Administration on Oct. 25 and went on sale a few weeks ... called Emend, plus the introduction of Arcoxia in ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Первый за 10 лет препарат Ñ? новым механизмом дейÑ?твиÑ? длÑ? пред?  -  Jul 12, 2006
Emend ® рекомендуетÑ?Ñ? применÑ?ть перорально, один раз за три и менее чаÑ?а перед индукцией ... Emend ® — первый за более чем 10-летний период препарат Ñ? новым ... Ð?птека online

Merck 2006 Annual Business Briefing - Final.  -  Dec 12, 2006
MK-0517 is a prodrug of aprepitant the active ingredient in EMEND. ... As you know, we initially registered EMEND in oral therapy for the prevention of ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

Nausea? No need to suffer in silence .  -  Nov 1, 2006
Emend may be combined with another drug when chemotherapy, for example high-dosage cisplatin, is highly likely to cause nausea and vomiting . ... Times-News - Google News Archive

CMPH 20-23 March 2006 Initial Marketing Authorisation Applications - ...  -  Mar 20, 2006
Emend (aprepitant), from Merck Sharp & Dohme, to add prevention of post-operative ... Emend was first authorised in the European Union on 11 November 2003. ... Medical News Today - Medical News Today (press release)

Jane Brody: It's unnecessary for women to suffer from nausea,...  -  Nov 7, 2006
Emend may be combined with another drug when chemotherapy, for example high-dosage cisplatin, is highly likely to cause nausea and vomiting. ... Naples Daily News - Naples Daily News

FDA OKs drug for post-op nausea.(LATEBREAKERS)  -  Aug 7, 2006
Aprepitant (Emend, Merck) has been approved for a third indication: the prevention of ... Emend was previously approved to be used in combination with other ... Free with registration - Drug Topics - AccessMyLibrary.com

My .Notice .Name Is Watson Gregg And I'm A Candidate For County …  -  Nov 6, 2006
...education opportunities, tan breaks, and to emend sewer systems to possible industrial sites then I would appreciate your vote in the November election. ... The Dispatch - Google News Archive

Communications.(Letter to the Editor)  -  Mar 1, 2005
As with all responsible editions, such emendations are reported and discussed in a critical apparatus--as are refusals to emend, and variants in relevant ... $4.95 - Notes - ECNext

… Shakespearean authorship.(William Shakespeare's Sonnet 23)(Critical...  -  Jan 1, 2008
...(4) As Stephen Booth writes, "books is the Q reading and makes sense," so there is no need to emend it. (5) Some have argued that books can hardly be ... Pay-Per-View - Shakespeare Studies - HighBeam Research

FDA Weighs Risk of Vioxx Successor Drug | Article from AP Online | …  -  Apr 10, 2007
Corp., was approved by the Food and Drug Administration on Oct. 25 and went on sale a few weeks ... called Emend, plus the introduction of Arcoxia in ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

¿Náuseas? No hay razón para sufrir en silencio  -  Nov 28, 2006
Emend pudiera combinarse con otra droga cuando la quimioterapia, por ejemplo el cisplatin de elevada dosis, tiene muchas probabilidades de ocasionar náusea ... La Prensa - La Prensa (Panamá)

The distribution of infinitives in -e and -en in some Middle English ...  -  Sep 22, 2005
...poet's grammar of final -e and his metrical norms and rules can inform choices between textual variants and the decision as to whether or not to emend. ... $4.95 - Medium Aevum - ECNext

YOUR HEALTH / Cancer's other battlefields  -  Jun 9, 2008
Emend is expensive, however; at our local pharmacy, a three-day pack costs $418. Countering side effects is a crucial element of defeating cancer; ... $2.95 - Press of Atlantic City, The - NewsBank

Press Release: New Therapy by Merck is Positioned to Earn Gold- …  -  Apr 9, 2008
The regimen of Emend for Injection/Ivemend and 5-HT3 RA offers robust efficacy and key advantages in delivery as a result of its ... ... Pay-Per-View - PR Newswire - HighBeam Research

Drug Development; Committee for Medicinal Products for Human Use …  -  Apr 26, 2006
Emend (aprepitant), from Merck Sharp & Dohme, to add prevention of post-operative ... Emend was first authorized in the European Union on November 11, 2003. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Factiva Search  -  Apr 1, 2006
Emend approval for preventing nausea ). 01 April, 2006 Internal Medicine News. Emend (aprepitant) has been approved for use with other antiemetic medicines ... Pay-Per-View - Internal Medicine News - Factiva, from Dow Jones

Company Profile Report  -  Apr 5, 2008
Emend For Injection (Intravenous Aprepitant); Emend (Aprepitant). Liver Disorders. Cirrhosis. Complications. Edema. Loop Diuretic Agents ... $50.00 - Revere Reports - Revere

Avastin Labeling Gets Additional Warning  -  Jan 14, 2005
Merck's anti-emetic Emend will qualify for coverage as a Medicare Part B drug ... The CMS proposal calls for Emend (aprepitant) to be covered when used as ... Pay-Per-View - Washington Drug Letter - Factiva, from Dow Jones

The distribution of infinitives in -e and -en in some Middle English ...  -  Sep 22, 2005
...poet's grammar of final -e and his metrical norms and rules can inform choices between textual variants and the decision as to whether or not to emend. ... Pay-Per-View - Medium Aevum - HighBeam Research

Serwis informacyjny 7.09.2007 , pulsmedycyny.com.pl  -  Sep 7, 2007
Emend był zwykle dobrze tolerowany. Większość działań niepożądanych zaobserwowanych w badaniach klinicznych miała nasilenie łagodne do umiarkowanego. ... Puls Medycyny

Drugmakers Focus on Cancer Cures  -  Mar 17, 2005
Perhaps the most pronounced efforts are at Merck, which doesn't sell any cancer treatments although it does have Emend, a product for nausea caused by ... FOXNews

MPF defende remédio para quimioterapia  -  Jan 30, 2008
Quando aplicado em domicílio, a segunda ea terceira dose de Emend depende dos programas de assistência farmacêutica previstos pelos planos de saúde. ... Saúde Business Web

New frontiers: if you're not yet familiar with immunopharmacology, …  -  Mar 1, 2006
The antiemetic aprepitant (Emend)--approved in 2003 for treating nausea and vomiting in patients undergoing chemotherapy--was the first new drug formulated ... Pay-Per-View - RN - Factiva, from Dow Jones

'Brookland' - New York Times  -  Apr 9, 2006
My silence on this matter has been partly due to bad character; which I hope at this late date I can emend. You ask for the story of the bridgeworks, ... New York Times

The cancer drug  -  Dec 22, 2007
But now they have great new drugs, such as Emend, dexamethasone and Ativan, that keep the nausea and other pain at bay. He said the people who use pot now ... Los Angeles Times

If you hear an Almighty guffaw, at least Somebody is reading this  -  Oct 26, 2005
...but you would be jumping to that assumption, because The Times would emend a little h to a big one, even if I didn't believe in Him. ... Times Online

Brand Names/Synonyms:
EMEND is also known by the following brand names and/or synonymsAprepitant; Aprepitant [Usan]; Emend; MK 0869; MK 869

Drug Category:
EMEND is categorized under the following by the FDA: Antiemetics; ATC:A04AD12

Dosage Forms:
CAPSULE

Absorption:
The mean absolute oral bioavailability of aprepitant is approximately 60 to 65%.

Interactions:
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Chemical IUPAC Name:
5-[[2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one





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