Emtricitabine

This page contains recent news articles, when available, and an overview of Emtricitabine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Emtricitabine
(when available)

Pharmacology and use:
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Emtricitabine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated. For the treatment of HIV-1 infection in adults.

Mechanism Of Action:
Emtricitabine, a synthetic nucleoside analogue of cytidine, is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate. Emtricitabine substrate deoxycytidine 5'-triphosphate and by incorporating into nascent viral DNA, which results in chain termination. Emtricitabine 5'-triphosphate is a weak inhibitor of mammalian DNA polymerases alpha, beta, and epsilon and of mitochondrial DNA polymerase gamma. Emtricitabine inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA.

News Articles on Emtricitabine

Rilpivirine/Truvada Combo Pill Could Earn $2 Billion Yearly  -  ‎Jan 4, 2010‎
...(tenofovir plus emtricitabine) is expected to achieve “blockbuster sales� in the coming decade—earning up to $2 billion per year in the United States, ... AIDSmeds.com HIV/AIDS Treatment News

The Top Five Biotech Innovations of the 2000s  -  ‎Dec 14, 2009‎
2) HIV therapies such as Gilead Sciences' combination of efavirenz, emtricitabine, and tenofovir (Atripla). 4) Therapies for hepatitis C such as Vertex ... Xconomy

Study Identifies Viread And Emtriva As The Preferred Initial Treatment For HIV ...  -  ‎Dec 10, 2009‎
A recent study finds Viread (tenofovir) and Emtriva (emtricitabine) are more effective nucleoside reverse transcriptase inhibitors (NRTIs) than Ziagen ... The AIDS Beacon (blog)

US rolls back AIDS drug prevention trial in Botswana  -  ‎Dec 17, 2009‎
It was using Gilead Sciences Inc's Truvada, a combination of two drugs called tenofovir and emtricitabine. The CDC did not release the data on how many ... Reuters South Africa

Reyataz and Sustiva Co-Pay Programs Expanded  -  ‎Dec 18, 2009‎
Atripla (which contains efavirenz, tenofovir and emtricitabine) will continue to be a part of the older program for the time being, which asks people to ... AIDSmeds.com HIV/AIDS Treatment News

EEUU modifica ensayo de medicina preventiva de sida en Botsuana  -  ‎Dec 17, 2009‎
En las pruebas se usó el Truvada de Gilead Sciences Inc, una combinación de dos drogas llamadas tenofovir y emtricitabine. No se publicaron datos respecto a ... Reuters América Latina

Generic Name: Tenofovir, emtricitabine  -  ‎Nov 11, 2009‎
Truvada (generic name: emtricitabine / tenofovir) belongs to a class of medicines known as HIV-1 nucleoside analog reverse transcriptase inhibitors (NRTIs). ... Pattaya Daily News

Post-Exposure Prophylaxis of HIV Transmission Spotlighted Case vignette of ...  -  ‎Oct 28, 2009‎
...we would recommend a 28-day course of tenofovir plus emtricitabine with or without a boosted protease inhibitor such as ritonavir-lopinavir; however, ... ModernMedicine

FDA Approves Labeling Update for REYATAZ® (atazanavir sulfate) Capsules to ...  -  ‎Nov 5, 2009‎
Each was given in combination with a once-daily, fixed-dose combination of tenofovir disoproxil fumarate 300 mg/emtricitabine 200 mg. ... WELT ONLINE

FDA OKs Labeling Update for Reyataz Capsules  -  ‎Nov 9, 2009‎
Each was given in combination with a once-daily, fixed-dose combination of tenofovir disoproxil fumarate 300 mg/emtricitabine 200 mg. ... Trading Markets (press release)

Concert Starts HIV Trial, Bags $12M From Glaxo to Help Challenge Gilead's Once ...  -  ‎Nov 9, 2009‎
...be combined with other antivirals to create a convenient once-daily pill to compete with Gilead Sciences' efavirenz emtricitabine tenofovir (Atripla), ... Xconomy

France Innovation Scientifique & Transfert Publishes a New Report on the HIV ...  -  ‎Nov 3, 2009‎
This position is therefore not a result of internal research but is based on the acquisition of key molecules such as emtricitabine coming from a ... Reuters

GileadAnnouncesLong-TermDatafromTwo PivotalPhaseIIIStudiesEvaluatingViread ...  -  ‎Oct 31, 2009‎
After 72 weeks, patients with confirmed viremia (HBV DNA levels at or above 400 copies/mL on two consecutive visits) had the option of adding emtricitabine ... Reuters

Epzicom Associated With More Side Effects In HIV/AIDS Patients Than Truvada  -  ‎Nov 9, 2009‎
Truvada is a combination therapy that includes the drugs Emtriva (emtricitabine) and Viread (tenofovir). Alternatively, Epzicom is a combination therapy ... The AIDS Beacon (blog)

Gilead reports positive results from two Phase III hepatitis trials  -  ‎Nov 3, 2009‎
After 72 weeks, patients with confirmed viremia had the option of adding emtricitabine treatment by substituting Truvada for Viread. ... Trading Markets (press release)

No Heart Rhythm Problem With 25 mg of Rilpivirine  -  ‎Nov 5, 2009‎
Rilpivirine, combined with Truvada (tenofovir plus emtricitabine), is currently in Phase III studies involving treatment-naive individuals. ... AIDSmeds.com HIV/AIDS Treatment News

Canada approves ISENTRESS(R) for adults starting HIV treatment  -  ‎Oct 20, 2009‎
Both medicines were administered in combination with tenofovir and emtricitabine. The treatment-naïve indication for raltegravir in combination therapy was ... CNW Telbec (Communiqué de presse)

GileadSciencesannonce des résultats financiers record pour le troisième ...  -  ‎Oct 23, 2009‎
Autres produits antiviraux Les ventes des autres produits antiviraux, qui comprennent l`Hepsera® (adéfovir dipivoxil) et l`Emtriva® (emtricitabine) se sont ... Reuters

GILEAD SCIENCES : annonce des résultats financiers record pour le troisième ...  -  ‎Oct 23, 2009‎
Les ventes des autres produits antiviraux, qui comprennent l'Hepsera ® (adéfovir dipivoxil) et l'Emtriva ® (emtricitabine) se sont élevées à 74,7 millions ... Zonebourse.com

Le Canada approuve ISENTRESS(MC) pour les adultes commençant un traitement ...  -  ‎Oct 20, 2009‎
Les deux médicaments ont été administrés dans le cadre d'une polythérapie avec le ténofovir et l'emtricitabine. L'indication d'utiliser le raltégravir chez ... CNW Telbec (Communiqué de presse)

Bloomberg Printer-Friendly Page  -  Dec 11, 2007
Emtricitabine and tenofovir disoproxil fumarate are commercialized by ... Due to similarities between emtricitabine and lamivudine, ATRIPLA should not be ... Bloomberg

Researchers find better HIV medication  -  Jan 19, 2006
The regimen became even simpler in 2004, when tenofovir and emtricitabine, approved by the US Food and Drug Administration (FDA) in 2001 and 2003 ... 新�网

Gilead says Teva files to sell generic of HIV drug  -  Nov 14, 2008
Gilead said Teva has claimed that two of the patents associated with emtricitabine -- owned by Emory University and licensed Gilead -- are invalid or ... Reuters

… Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/...  -  Oct 17, 2007
ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate [DF] 300 mg) is indicated for use alone as a complete regimen or in ... Free with registration - PR Newswire - AccessMyLibrary.com

Tenofovir Plus Emtricitabine Combo May Protect From HIV Transmission  -  Mar 28, 2006
According to new research, the combination of tenofovir with emtricitabine - under the trade name Truvada - can protect monkeys from getting the AIDS virus. ... Medical News Today - Medical News Today (press release)

Emtricitabine and Tenofovir ( Systemic).  -  Jul 28, 2005
Emtricitabine (em-trye-SYE-ta-been) and tenofovir (te-NOE-foe-veer) combination is used with other anti-HIV medicines in the treatment of human ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Learn about Emtricitabine from Consumer Reports Health.  -  Jan 6, 2007
Medications that are similar to emtricitabine have caused serious damage to the liver and a ... Full Alert. Emtricitabine is used with other medications to ... consumerreports.org

Bristol-Myers in Pact for HIV Pill  -  Sep 28, 2006
Atripla is a once-daily, single-tablet regimen for the treatment of HIV-1 infection in adults that combines efavirenz, emtricitabine and tenofovir ... TheStreet.com - TheStreet.com (subscription)

Emory University to get $525 million for AIDS drug  -  Jul 19, 2005
Emtricitabine, marketed by Gilead as Emtriva, was first approved by the US Food and Drug Administration in July 2003 for the treatment of HIV infection in ... Bizjournals.com

Boehringer Ingelheim drug in combination halves HIV resistance risk -...  -  Nov 7, 2007
The trial showed that women given a combination of tenofovir and emtricitabine along with the nevirapine were 53 pct less likely to develop higher ... Forbes

Mmegi Online ::> news we need to know  -  Jan 24, 2006
Tenofovir DF and emtricitabine are relatively new drugs, approved by the US Food and Drug Administration (FDA) in 2001 and 2003 respectively. ... Mmegi Online

Gilead Sciences files patent lawsuit against Teva Pharmaceuticals...  -  Dec 12, 2008
Both patents are associated with emtricitabine, a component of Truvada, and are licensed exclusively to Foster City-based Gilead (NASDAQ: GILD) by Emory ... Bizjournals.com

US university sells rights to Aids drug it developed for $525m.  -  Jul 21, 2005
The Atlanta institution decided to accept a one-off sum for its rights to the emtricitabine treatment, marketed as Emtriva, rather than continue collecting ... Pay-Per-View - Irish Times - Factiva, from Dow Jones

… For ATRIPLA(R) (Efavirenz 600mg/Emtricitabine 200 Mg/Tenofovir …  -  Oct 22, 2007
Emtricitabine and tenofovir disoproxil fumarate are commercialized by ... Due to similarities between emtricitabine and lamivudine, ATRIPLA should not be ... Medical News Today - Medical News Today (press release)

Anti-AIDS combo said to work  -  Apr 3, 2006
The drugs are tenofovir (Viread) and emtricitabine, or FTC (Emtriva), sold in combination as Truvada by Gilead Sciences Inc. , a California company best ... Boston Globe

… Women Who Receive Tenofovir, Emtricitabine During Childbirth Have ...  -  Nov 9, 2007
Women assigned to take tenofovir and emtricitabine during childbirth were 53% less likely ... Women in the tenofovir-emtricitabine group had a 12% chance of ... Medical News Today - Medical News Today (press release)

Tenofovir DF, Emtricitabine, Efavirenz May Be Superior to Zidovudine.....  -  Jul 28, 2005
July 28, 2005 (Rio de Janeiro) -- An HIV treatment regimen combining tenofovir DF (Viread), emtricitabine (Coviracil), and efavirenz (Sustiva) has been ... Medscape

Atripla: efavirenz/emtricitabine/tenofovir disoproxil tablets.(New …  -  Aug 1, 2006
This fixed-dose combination tablet contains: efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI); emtricitabine, a synthetic nucleoside ... Free with registration - Formulary - AccessMyLibrary.com

… For ATRIPLA(R) (efavirenz 600 Mg/ Emtricitabine 200 Mg/tenofovir …  -  Oct 19, 2007
Emtricitabine and tenofovir disoproxil fumarate are commercialized by ... Due to similarities between emtricitabine and lamivudine, ATRIPLA should not be ... Medical News Today - Medical News Today (press release)

emtricitabine Japan Tobacco marketed, Japan (HIV infection) Japan …  -  Apr 25, 2005
On 8 April 2005 Japan Tobacco announced that it plans to launch emtricitabine (EMTRIVA), an oral nucleoside reverse transcriptase inhibitor, in Japan on 19 ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Aurobindo Pharma gets tentative approval for emtricitabine capsules  -  May 15, 2008
Aurobindo Pharma received a tentative approval from the US Food and Drug Administration, for emtricitabine capsules, used in combination with other ... Myiris.com

A Potential HIV Prophylactic?  -  Feb 6, 2006
Truvada contains the chemical tenofovir as well as emtricitabine. The latter is available on its own under the brand name Emtriva, a product also made by ... Red Herring

EMTRICITABINE AND TENOFOVIR DISOPROXIL FUMARATE (Oral route …  -  May 1, 2007
Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogs alone or in combination ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

… purchase from Emory University of Emtricitabine Royalty Interest...  -  Jul 25, 2005
Gilead and Royalty Pharma made a one-time cash payment of $525.0 million to Emory in exchange for the elimination of the emtricitabine royalties due to ... $4.95 - M2 Presswire - ECNext

HIV Patients With High Viral Load Worsen on Fixed-Dose Abacavir/ …  -  Aug 9, 2008
..."In the tenofovir/emtricitabine arm of the study there were 26 events at 24 weeks. These results reveal highly significant differences in the treatments (P ... DG News

'Pill to prevent AIDS shows promise'  -  Mar 29, 2006
The drugs are tenofovir (Viread) and emtricitabine, or FTC (Emtriva), sold in combination as Truvada by Gilead Sciences Inc, a California company best known ... Times of India

South Africa: Nod for Aids Drugs is Cost Poser for State  -  Apr 25, 2007
Viread contains tenofovir, while Truvada combines tenofovir with emtricitabine. Doctors and AIDS activists have for some time been calling for Viread and ... AllAfrica.com

A "Morning Before" Pill to Prevent HIV Infection  -  Feb 5, 2008
A somewhat odd study of macaques done by a group of researchers with the CDC demonstrated that two anti-retroviral medications, Emtricitabine and Tenofovir, ... io9

emtricitabine, tenofovir disoproxil Gilead Sciences clinical data...  -  Feb 14, 2005
Tenofovir disoproxil/emtricitabine-treated patients had a significantly greater increase in ... Emtricitabine, a nucleoside reverse transcriptase inhibitor, ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

HIV drugs to be subsidised  -  Mar 16, 2007
The medicines, Tenofovir (Viread) and Emtricitabine (Emtriva), ... Tenofovir and Emtricitabine were similar to other subsidised drugs but funding them was ... New Zealand Herald

Chronic Hepatitis B: Tenofovir Alone Versus Tenofovir With Emtricitabi...  -  Dec 31, 2008
From the American College of Gastroenterology and its member physicians, Digestive Health SmartBrief is a free, twice-weekly newsletter. ... SmartBrief

Once-Daily Tenofovir/Emtricitabine/Efavirenz Combination Linked to …  -  Sep 30, 2006
By Paula Moyer. SAN FRANCISCO, CA -- September 30, 2006 -- A once-daily regimen for the treatment of HIV, consisting of tenofovir (Viread), emtricitabine ... DG News

… -1 drug approved.(Products)(Truvada (tenofovir disoproxil/emtricitab...  -  Jan 1, 2005
Truvada (tenofovir disoproxil/emtricitabine) is a fixed-dose combination of the antiretroviral drugs tenofovir disoproxil fumarate (300 mg) and ... Free with registration - Family Practice News - AccessMyLibrary.com

Emtricitabine Side Effects from Consumer Reports Health.  -  Jan 6, 2007
Medications that are similar to emtricitabine have caused serious damage to the liver and a ... Full Alert. Medications that are similar to emtricitabine ... consumerreports.org

IAC: Unboosted Atazanavir HIV Regimen Found Inferior  -  Aug 8, 2008
The combination tested was didanosine (Videx), emtricitabine (Emtriva), and atazanavir (Reyataz), all taken once a day, according to Thomas Campbell, MD, ... MedPage Today

efavirenz + emtricitabine + tenofovir disoproxil Bristol-Myers Squibb...  -  May 8, 2006
...reverse transcriptase inhibitor efavirenz (SUSTIVA) (600 mg), and Gilead Sciences' TRUVADA, which comprises the nucleoside reverse transcriptase inhibitors ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Gilead Sciences counts on Indian pharma companies  -  May 14, 2007
The agreements entered into since last September cover two drugs, Emtriva (emtricitabine) and Viread (tenofovir disoproxil fumarate), and allows the Indian ... Hindu Business Line

… of Fixed-Dose Regimen of Truvada -emtricitabine and tenofovir...  -  Apr 26, 2005
Truvada combines Emtriva(R) (emtricitabine) and Viread(R) (tenofovir disoproxil fumarate) in one tablet taken once a day in combination with other ... $4.95 - Business Wire - ECNext

Health24 - News, HIV/Aids  -  Jan 17, 2008
None of the mice that received the antiretroviral drugs emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF) showed any evidence of infection, ... Health24.com

Preventing HIV Transmission with Tenofovir + Emtricitabine  -  Feb 6, 2006
...by Tim Horn. In recent years, there has been a lot of attention placed on the use of Viread® (tenofovir) for pre-exposure prophylaxis (PREP) against HIV ... AIDSmeds.com HIV/AIDS Treatment News

… ; Companies complete $525M purchase from Emory of emtricitabine …  -  Aug 23, 2005
Gilead and Royalty Pharma made a one-time cash payment of $525 million to Emory in exchange for the elimination of the emtricitabine royalties due to Emory ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Taking Emtricitabine from Consumer Reports Health.  -  Jan 6, 2007
Medications that are similar to emtricitabine have caused serious damage to the liver and a ... Full Alert. Emtricitabine may cause side effects. ... consumerreports.org

Efavirenz/emtricitabine/: tenofovir disoproxil tablets: Bristol-myers...  -  Sep 1, 2006
The combination of efavirenz, emtricitabine, and tenofovir disoproxil was approved on July 12, 2006, for use alone as a complete regimen or in combination ... Free with registration - Managed Healthcare Executive - AccessMyLibrary.com

tenofovir disoproxil + emtricitabine Gilead Sciences marketed,...  -  May 9, 2005
...tenofovir disoproxil + emtricitabine, emtricitabine + tenofovir disoproxil, TRUVADA, J5C1, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors, ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

How to take Emtricitabine from Consumer Reports Health.  -  Jan 6, 2007
Medications that are similar to emtricitabine have caused serious damage to the liver and a ... Full Alert. tell your doctor and pharmacist if you are ... consumerreports.org

EU application for HIV drug approval  -  Oct 10, 2006
The drug consists of three compounds – efavirenz, emtricitabine and tenofovir disoproxil fumarate – all of which are separately marketed as ... Hays Pharma

Gilead and Japan Tobacco Sign Licensing Agreement for Novel HIV …  -  Mar 22, 2005
Gilead and JT first partnered in July 2003, when the companies announced an agreement granting JT commercialization rights for Truvada(R) (emtricitabine and ... Free with registration - Business Wire - AccessMyLibrary.com

… : Abacavir/Lamivudine Not as Effective as Tenofovir/Emtricitabine  -  Jul 26, 2007
..."Noninferiority of abacavir/lamivudine vs tenofovir/emtricitabine could not be proven ... "A small benefit in favor of tenofovir/emtricitabine was observed, ... Medscape

tenofovir disoproxil + emtricitabine Gilead Sciences marketed, Canada...  -  Jun 26, 2006
...tenofovir disoproxil + emtricitabine, emtricitabine + tenofovir disoproxil, TRUVADA, J5C1, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors, ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Gilead licenses HIV integrase inhibitor.(Wednesday, March 23)(Gilead ...  -  Mar 28, 2005
The companies first partnered in July 2003 in an agreement that granted Japan Tobacco commercialization rights for Truvada (emtricitabine and tenofovir ... Free with registration - BioWorld Week - AccessMyLibrary.com

Netherlands Corporate News - Gilead meldt gegevens overstap van …  -  Oct 29, 2007
In the SWEET (Simplification With Easier Emtricitabine and Tenofovir) study, patients who switched from Combivir to Truvada, both in combination with ... Netherlands Corporate News - Netherlands Corporate News (persbericht)

Starting or Switching: Truvada Outpaces Combivir in Studies  -  Jul 26, 2007
Three-year safety and efficacy of emtricitabine (FT)/tenofovir DF (TDF) and efavirenz (EFV) compared to fixed dose zidovudine/lamivudine (CBV) in ... AIDSmeds.com HIV/AIDS Treatment News

… ATRIPLA(TM) (efavirenz 600 mg/ emtricitabine 200 mg/ tenofovir dis  -  Jul 12, 2006
Since ATRIPLA contains efavirenz, emtricitabine and tenofovir disoproxil ... Due to similarities between emtricitabine and lamivudine, ATRIPLA should not be ... Free with registration - PR Newswire - AccessMyLibrary.com

Guidelines for nonoccupational HIV prophylaxis: data back the use of...  -  Mar 1, 2005
The drugs in the preferred nonnucleoside reverse transcriptase inhibitor (NNRTI)--based regimen are efavirenz plus either lamivudine or emtricitabine plus ... Free with registration - Skin & Allergy News - AccessMyLibrary.com

New HIV listings added to Pharmaceutical Schedule  -  Apr 1, 2007
Saag,M et al Efficacy and Safety of emtricitabine vs stavudine in combination therapy ... Tenofovir disoproxil fumarate, emtricitabine and efavirenz versus ... scoop.co.nz

Gilead shifts Irish ops  -  Apr 12, 2007
Major products for the company include Atripla (efavirenz, emtricitabine, tenofovir), the only once-daily single tablet regimen for HIV-1 infection, ... In-PharmaTechnologist.com

Switching From Zidovudine- to Tenofovir-Based Therapy Preserves and …  -  Feb 6, 2008
An earlier switch to tenofovir/emtricitabine, the authors noted, ... They concluded that tenofovir/emtricitabine maintains virologic control while ... DG News

Similar Efficacy, Better Triglycerides with Invirase vs. Kaletra  -  Oct 26, 2007
Saquinavir/r (SQV/r) BiD versus lopinavir/r (LPV/r) BiD, plus emtricitabine/tenofovir (FTC/TDF) QD as initial therapy in HIV-1 infected patients: the GEMINI ... AIDSmeds.com HIV/AIDS Treatment News

CHMP recommends approval of Atripla for HIV-1.  -  Oct 29, 2007
...granting marketing authorization for the combination HIV drug Atripla (efavirenz 600mg; emtricitabine 200mg; tenofovir disoproxil fumarate 300mg). ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

efavirenz + emtricitabine + tenofovir disoproxil Bristol-Myers Squibb...  -  May 9, 2005
Gilead Sciences announced on 26 April 2005 that it is proceeding with development of a second, once-daily, fixed dose formulation of a tenofovir ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

… Therapy; Mechanism of HIV-1 emtricitabine and lamivudine resistance...  -  Mar 14, 2006
2006 MAR 14 - (NewsRx.com) -- A study from the United States has chronicled virologic and enzymatic studies that revealed the mechanism of K65R- and ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

tenofovir disoproxil + emtricitabine Gilead Sciences marketed, Mexico...  -  May 8, 2006
...tenofovir disoproxil + emtricitabine, emtricitabine + tenofovir disoproxil, TRUVADA, J5C1, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors, ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

… Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovi...  -  Dec 17, 2007
European Commission Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet ... Pay-Per-View - PR Newswire - HighBeam Research

Once-daily single pill simplifies HIV cocktail.  -  Aug 21, 2006
Through 48 weeks, 84% of efavirenz/emtricitabine/tenofovir patients achieved and maintained viral loads less than 400 copies/ml (versus 73% in the other ... $9.94 - Drug Topics - Alacra Store

Gilead HIV Drug Combo Beats GSK Rival in Phase III Trial  -  Jan 20, 2006
Viread and Emtriva are often prescribed together as a fixed-dose combination tablet called Truvada (emtricitabine and tenofovir disoproxil fumarate), ... RedOrbit

A single daily pill for HIV  -  Aug 7, 2006
The new pill, named Atripla, combines efavirenz (Sustiva), emtricitabine (Emtriva), and tenofovir (Viread). It is a milestone in AIDS treatment. ... Cortlandt Forum

… Approves ATRIPLA(R) (Efavirenz 600 mg/Emtricitabine 200 mg/Tenofovi...  -  Dec 17, 2007
European Commission Approves ATRIPLA(R) (Efavirenz 600 mg/Emtricitabine 200 mg/Tenofovir Disoproxil (as Fumarate) 245 mg), the First Once-Daily Single ... Pay-Per-View - PR Newswire Europe - HighBeam Research

US stops trial of interrupted HIV treatment  -  Jan 18, 2006
..."The implications are quite clear for patients with HIV who are about to start therapy: The simple combination of tenofovir and emtricitabine, ... RedOrbit

Gilead will license tenofovir to Indian companies; Merck to take...  -  Jul 26, 2006
The company also revealed that global marketing of the new triple combination pill containing tenofovir, emtricitabine and efavirenz is likely to be handled ... Aidsmap

Truvada combo a no go?  -  Aug 22, 2005
Gilead's Truvada (emtricitabine and tenofovir disoproxil fumarate) with ... of Viread (tenofovir disoproxil fumarate) and Emtriva (emtricitabine). ... ICIS

AASLD: Tenofovir Found Superior to Adefovir in Chronic Hepatitis B at...  -  Nov 12, 2007
Participants were either treatment-naive or had previous experience with lamivudine or emtricitabine. Three hundred and seventy-five patients were ... MedPage Today

EC Approves BMS-Gilead AIDS Drug  -  Dec 18, 2007
Atripla (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg) is used to treat HIV-1 infection in adults. ... FDA news - FDA news (subscription)

abc13.com: Health news from KTRK about you and your family 7/31/06  -  Jul 31, 2006
Atripla combines Viread (tenofovir), Emtriva (emtricitabine) and Sustiva (efavirenz). Viread and Emtriva, both made by Gilead of Foster City, Calif., ... go.com

Press Release: Mylan Announces Tentative FDA Approval Under …  -  Dec 4, 2007
PR Newswire; October 17, 2007 ; 700+ words ... ... emtricitabine 200 mg/tenofovir ... Emtricitabine and tenofovir disoproxil fumarate are commercialized ... Pay-Per-View - PR Newswire - HighBeam Research

Once-a-day HIV pill.(CLINICAL CAPSULES)(Brief Article)  -  Feb 1, 2005
Squibb's drug Sustiva (efavirenz), and Gilead's drug Truvada, which combines Emtriva (emtricitabine) and Viread (tenofovir disoproxil fumarate). ... Free with registration - Internal Medicine News - AccessMyLibrary.com

AIDS drug combo may also be effective in preventing spread of HIV  -  Mar 31, 2006
The drug combo, currently sold under the trade name Truvada, contains the compounds tenofovir and emtricitabine, and is currently approved by the FDA to ... PR Week - PRWeek

GB AIDS Drugs Plant “Pivotalâ€?  -  Sep 6, 2005
Gilead announced a significant price reduction for Viread [tenofovir disoproxil fumarate] and Truvada [emtricitabine and tenofovir disoproxil fumarate] ... Bahama Journal - The Bahama Journal

Pill against HIV infection soon: Scientists : HindustanTimes.com  -  Mar 25, 2007
The drugs are tenofovir (Viread) and emtricitabine, or FTC (Emtriva), sold in combination as Truvada by Gilead Sciences Inc, a California company best known ... HT Tabloid

Gilead extends access programme for tenofovir, Truvada to Central …  -  Mar 17, 2005
Gilead Sciences is to offer its antiretroviral drug tenofovir (Viread) and its fixed dose combination Truvada (tenofovir and emtricitabine) to 15 countries ... Aidsmap

INDIA'S CIPLA LAUNCHES NEW ANTI-HIV DRUG VIRADAY.  -  Oct 13, 2006
Viraday is a combination of three anti-HIV drugs - Efavirenz 600 mg, Tenofovir 300 mg and Emtricitabine 200 mg, a company official said here. ... Free with registration - AsiaPulse News - AccessMyLibrary.com

Truvada get EU market approval.(Brief Article)  -  Mar 7, 2005
...which is a fixed-dose once-a-day combined formulation of its anti-HIV drugs Viread (tenofovir disoproxil fumarate) and Emtriva (emtricitabine). ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

CASE STUDY #3 CHANGING HANDS  -  Apr 4, 2005
Under the alliance, Abbott was to manufacture emtricitabine and comarket the ... Abbott also agreed to transfer the emtricitabine manufacturing process to ... Environmental Science & Technology

New Gold Standard for Initial Antiretroviral Treatment of HIV...  -  Jan 17, 2006
..."The implications are quite clear for patients with HIV who are about to start therapy: The simple combination of tenofovir and emtricitabine, ... newswise.com

Business Update; Gilead to develop, commercialize JTK-303 anti-HIV …  -  Apr 18, 2005
Viread (tenofovir disoproxil fumarate), Emtriva (emtricitabine) and Truvada (emtricitabine and tenofovir disoproxil fumarate) in Japan. ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

Investor Group acquires Emory-Emtriva Brand Rights from Emory …  -  Jul 22, 2005
Until such…emtricitabine royalty interest owned by Emory University for ... I will begin the…and the royalty buyout from [Emory's] Emtricitabine sales, ... Pay-Per-View - deals - Alacra Store

Gilead and Japan Tobacco pen HIV licensing deal  -  Mar 23, 2005
Gilead and JT first partnered in July 2003, when the companies announced an agreement granting JT commercialization rights for Truvada (emtricitabine and ... Pay-Per-View - Datamonitor News and Comment - Factiva, from Dow Jones

Gilead beats consensus; HIV drugs drive growth.(Thursday, October 20)  -  Oct 24, 2005
Gilead's combined HIV drug, Truvada (emtricitabine and tenofovir disoproxil fumarate), recorded sales of $162.4 million, a 32 percent increase over the ... Pay-Per-View - BioWorld Week - Factiva, from Dow Jones

Gilead's 2nd-qtr revenues up 55%.(Brief Article)  -  Aug 1, 2005
Emtriva (emtricitabine) revenues declined 26% to $12.1 million. Elsewhere, sales of AmBisome (amphotericin B) liposome for injection grew 2% to $56.2 ... $4.95 - Pharma Marketletter - ECNext

Gilead Sciences, Inc. Companies ink licensing agreement for HIV …  -  Apr 20, 2005
Gilead and JT first partnered in July 2003, when the companies announced an agreement granting JT commercialization rights for Truvada (emtricitabine and ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Study Sets New Gold Standard For Initial Antiretroviral Treatment Of...  -  Jan 25, 2006
..."The implications are quite clear for patients with HIV who are about to start therapy: The simple combination of tenofovir and emtricitabine, ... sciencedaily.com

Initial Antiretroviral Treatment of HIV Infection  -  Mar 10, 2006
..."The implications are quite clear for patients with HIV who are about to start therapy: The simple combination of tenofovir and emtricitabine, ... emaxhealth.com

Netherlands Corporate News - Bristol-Myers Squibb en Gilead Sciences ...  -  Nov 12, 2007
Emtricitabine and tenofovir disoproxil fumarate are commercialized by ... Due to similarities between emtricitabine and lamivudine, ATRIPLA should not be ... Netherlands Corporate News - Netherlands Corporate News (persbericht)

Cutaneous Reactions Associated with Newer Antiretroviral Agents  -  Nov 1, 2006
These include 3 NRTIs: abacavir, emtricitabine, and tenofovir; 4 PIs: atazanavir, ... Emtricitabine is an NRTI that was approved for use in 2003. ... Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com

Gilead's 1st-qtr sales reach $692.9M, up 61%.(sales and earnings of …  -  May 15, 2006
Gilead says that its success has been driven by sales of its HIV product franchise, which includes Truvada (emtricitabine and tenofovir disoproxil fumarate) ... $4.95 - Pharma Marketletter - ECNext

Board Says Stop Experimental Treatment Regimen In HIV Study  -  May 28, 2008
2. emtricitabine + atazanavir + ddI-EC (an experimental regimen taken once ... Those participants who have been taking emtricitabine + atazanavir + ddI-EC ... emaxhealth.com

Looking to the Future: New Agents for Chronic Hepatitis B  -  Jul 15, 2005
Emtricitabine (FTC) is similar in structure and activity to lamivudine (3TC), ... Resistance at 48 wk was recorded in 12.6% of the emtricitabine group, ... Nature.com

Article: Foster City firm's AIDS drug ready for human trials. - San...  -  May 12, 2006
Truvada(TM) Combines Anti-HIV Drugs Emtriva ... granting a Marketing Authorisation for Truvada(TM) (emtricitabine and tenofovir ... following a positive ... Pay-Per-View - San Jose Mercury News - HighBeam Research

Article: New drug combination to be tested in people to block AIDS...  -  May 11, 2006
Truvada(TM) Combines Anti-HIV Drugs Emtriva ... granting a Marketing Authorisation for Truvada(TM) (emtricitabine and tenofovir ... following a positive ... Pay-Per-View - San Jose Mercury News - HighBeam Research

Netherlands Corporate News - Amerikaanse Food and Drug …  -  Dec 7, 2006
Since ATRIPLA contains efavirenz, emtricitabine and tenofovir disoproxil ... Due to similarities between emtricitabine and lamivudine, ATRIPLA should not be ... Netherlands Corporate News - Netherlands Corporate News (persbericht)

Article: Triumphant combination.(TRUVADA: Marketing Team of the Year,...  -  Jan 1, 2007
Medical Letter on the CDC & FDA; December 19, 2004 ; 700+ words ... ... granting a marketing authorization for Truvada (emtricitabine and tenofovir ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Brand Names/Synonyms:
Emtricitabine is also known by the following brand names and/or synonyms524W91; BW 1592; BW 524W91; Coviracil; DRG-0208; Dotfc; Emtricitabine; Emtriva; FTC; Racivir; Truvada

Drug Category:
Emtricitabine is categorized under the following by the FDA: Anti-HIV Agents; ATC:J05AF09

Dosage Forms:
TABLETS

Absorption:
Rapidly absorbed (93%)

Interactions:
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Chemical IUPAC Name:
4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-pyrimidin-2-one





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