Enfuvirtide

This page contains recent news articles, when available, and an overview of Enfuvirtide but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Enfuvirtide
(when available)

Pharmacology and use:
Not Available For treatment of HIV AIDS

Mechanism Of Action:
Not Available

News Articles on Enfuvirtide

Trimeris Back to Square One as Arigene Buyout Collapses  -  ‎Dec 29, 2009‎
...leaving the Durham, NC-based firm to seek out other strategic moves as it faces decreasing sales of HIV drug Fuzeon (enfuvirtide). ... BioWorld Online

AIDS: Experts call for monitoring of resistance to ARVs  -  ‎Dec 31, 2009‎
Enfuvirtide, a fusion inhibitor, was the first molecule to obtain approval. The approval of Maraviroc (a CCR5 antagonist) is promising and evidence of its ... Africa Science News Service

Antiretroviral-Experienced Patients Maintain HIV Suppression Through 144 Weeks ...  -  ‎Nov 1, 2009‎
...and about 25% of those patients were put on the injectable entry inhibitor enfuvirtide as a new medication in the optimised background treatment. ... DG News

Sur le Web du CNRS  -  ‎Nov 3, 2009‎
...non nucléosidiques de la transcriptase inverse, inhibiteurs de la protéase ou l'inhibiteur de fusion du VIH, l'enfuvirtide, n'a pas montré d'antagonisme. Femmes et sida

ì—?ì?´ì¦ˆ 치료, 어떻게 가능한가?  -  ‎Oct 25, 2009‎
...현재는 융합억제(fusion inhibition)ë?¼ê³  하는 기술ì?„ 탑재한 'Enfuvirtide' 성분ì?˜ 치료제가 2003ë…„ 미국 FDAì?˜ 승ì?¸ì?„ 받아 íŒ?매 중ì?´ë©° 가장 대표ì ?ì?¸ 제품ì?´ 퓨 ... 파이낸스 투데이

Enfuvirtide, a peptide therapeutic derived from a protein subdomain  -  Feb 7, 2006
In March 2003, the 36-mer anti-HIV peptide enfuvirtide (Fuzeon, Trimeris/Roche) received US FDA approval. This drug is a natural interfacial sequence taken ... Nature.com

New anti-HIV drug will save lives, Aids foundation says  -  Aug 24, 2006
Enfuvirtide is used in combination with other drugs, and injected twice daily. ... Pharmac's medical director Peter Moodie said enfuvirtide was used to ... New Zealand Herald

Importance of the drug Fuzeon (enfuvirtide) in the management of HIV  -  Oct 20, 2005
New potent combinations make suppression of virus to undetectable levels more achievable for treatment-experienced HIV patients. ... News-Medical.net

Learn about Enfuvirtide Injection from Consumer Reports Health.  -  Jan 4, 2008
Enfuvirtide is used in combination with other medications to treat human immunodeficiency virus (HIV) infection in people who have not responded well enough ... consumerreports.org

… Show High Response Rates for Enfuvirtide Combined With Darunavir...  -  Jul 25, 2007
By Rachel Parratt. SYDNEY, AUSTRALIA -- July 25, 2007 -- Nearly two thirds of triple-class, treatment-experienced HIV patients achieved undetectable levels ... DG News

Cost-Efficacy Comparison among Three Antiretroviral Regimens in HIV...  -  Aug 8, 2007
The cost effectiveness of the ARV agent enfuvirtide has been shown to be ... However, an evaluation of enfuvirtide treatment costs that considers the impact ... Medscape

Enfuvirtide (Systemic).  -  Feb 1, 2006
Enfuvirtide ( en-FYOO-vir-tide) is used, in combination with other medicines, in the treatment of the infection caused by the human immunodeficiency virus ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Enfuvirtide Appears Safe, Prevents Transmission of HIV to Newborns in...  -  Feb 7, 2008
By Ed Susman. BOSTON, MA -- February 7, 2008 -- Faced with late-presenting pregnant women with high blood levels of HIV and no antenatal prophylaxis, ... DG News

HIV/AIDS Therapy; Antiretroviral enfuvirtide is not an inhibitor of...  -  Mar 21, 2005
According to recent research from France, "Enfuvirtide is a 36 amino-acid synthetic peptide derived from the HR2 sequence of the HIV-1 gp41. ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

Enfuvirtide (Systemic).(Drug overview)  -  May 1, 2006
Enfuvirtide ( en-FYOO-vir-tide) is used, in combination with other medicines, in the treatment of the infection caused by the human immunodeficiency virus ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

HIV/AIDS Therapy; Enfuvirtide improves health-related quality of life...  -  Mar 23, 2005
According to recently published review in the journal Medecine Et Maladies Infectieuses, "In combination with other antiretroviral drugs, enfuvirtide is ... Pay-Per-View - Immunotherapy Weekly - Factiva, from Dow Jones

TMC-125 and darunavir show strong effect in highly treatment- …  -  Jul 6, 2007
Conversely, in patients who took TMC-125 without enfuvirtide, ... The use of enfuvirtide (T-20) in patients with some degree of resistance to darunavir ... Aidsmap

How to take Enfuvirtide Injection from Consumer Reports Health.  -  Jan 4, 2008
...tell your doctor and pharmacist if you are allergic to enfuvirtide, mannitol, or any other medications. tell your doctor and pharmacist what prescription ... consumerreports.org

enfuvirtide Trimeris, Roche supplemental filing, USA (HIV infection).(...  -  Aug 1, 2005
Roche and Trimeris announced on 18 July 2005 that the US FDA has accepted their sNDA filing, seeking inclusion of information about the Biojector 2000 ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Needle-free administration of enfuvirtide reduces injection site...  -  Oct 6, 2006
A small eight-week study of a needle-free injection device for enfuvirtide (T-20, Fuzeon) sponsored by the drug's manufacturers, Roche and Trimeris, ... Aidsmap

Taking Enfuvirtide Injection from Consumer Reports Health.  -  Jan 4, 2008
Enfuvirtide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:. Some side effects can be serious. ... consumerreports.org

HIV/AIDS Therapy; Enfuvirtide improves health-related quality of life...  -  Mar 26, 2005
According to recently published review in the journal Medecine Et Maladies Infectieuses, "In combination with other antiretroviral drugs, enfuvirtide is ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

… -Site Reactions Switched From Enfuvirtide to Raltegravir: Presented...  -  Aug 7, 2008
Patients who take enfuvirtide frequently experience injection-site reactions ... [Presentation title: Retrospective Analysis of a Switch From Enfuvirtide to ... DG News

Discovery of an HIV inhibitor in human blood points to new type of...  -  Apr 20, 2007
The modified forms were equally active against all drug-resistant viruses tested, including those showing resistance to enfuvirtide. ... Aidsmap

Enfuvirtide As Rescue Therapy  -  Oct 23, 2006
October 23, 2006 (Reuters Health)—Findings from a small study suggest that the fusion inhibitor enfuvirtide (formerly T-20) is a useful therapeutic option ... AIDSmeds.com HIV/AIDS Treatment News

Efficacy and Safety of Etravirine (TMC125) in Patients With Resistant...  -  Oct 26, 2005
Despite stratification by intended enfuvirtide use, there was less use of ... In addition, more control patients were enfuvirtide-experienced (72.5 versus ... Medscape

ICAAC: Elvitegravir Study Underlines Need for Several HIV Drugs  -  Sep 20, 2007
Some patients were also allowed to use enfuvirtide for the first time during the study, Dr. Zolopa said, and it was on those patients that he focused at ... MedPage Today

Vincent V Soriano, MD, PhD  -  Jul 21, 2006
Patients with documented enfuvirtide resistance mutations who remain on drug ... The fact that enfuvirtide resistance mutations tend to rapidly disappear ... Medscape

New Interim Results Demonstrate High Response Rate with FUZEON® …  -  Jul 23, 2007
...“Previous studies had provided encouraging – but limited – information on the use of enfuvirtide in combination with darunavir/r,� said Edwin DeJesus, MD, ... webwire.com

… -Infected Patients Prefer Needle-Free Enfuvirtide System: Presented...  -  Oct 2, 2006
By Ed Susman. SAN FRANCISCO, CA -- October 2, 2006 -- Patients with HIV who have to take enfuvirtide (Fuzeon) as part of their treatment regimen prefer a ... DG News

enfuvirtide Trimeris, Roche receive FDA approvable letter requesting ...  -  Dec 5, 2005
Roche and Trimeris announced on 23 November 2005 that the US FDA has issued an approvable letter relating to the use of enfuvirtide (FUZEON) in the ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

… ) Anti-CD4 Antibody Synergistic With Enfuvirtide Against HIV-1  -  Jul 7, 2006
Friday July 7, 2006 (Reuters Health) - The humanized monoclonal anti-CD4 antibody TNX-355 is synergistic with the fusion inhibitor enfuvirtide (T-20) in ... AIDSmeds.com HIV/AIDS Treatment News

Medical News: General Infectious Disease  -  Dec 21, 2007
The anti-HIV drug enfuvirtide (Fuzeon) -- an "entry inhibitor" -- acts in much the same way, the researchers said, adding that they are encouraged by the ... MedPage Today

Abstract and Introduction  -  Nov 30, 2005
Results: A total of 73.7% of patients randomized to the enfuvirtide group ... Conclusion: These data demonstrate durable efficacy of enfuvirtide plus OB ... Medscape

IAS: Needle-free T-20 delivery reduces, but does not eliminate,...  -  Jul 29, 2005
A needle-free way of delivering T-20 (enfuvirtide, Fuzeon) is easier to use and reduces, ... Administration of Enfuvirtide with Biojector 2000 demonstrates ... Aidsmap

New Data Show Enfuvirtide Continues to Provide Significant Immune …  -  Jun 30, 2006
NUTLEY, NJ and MORRISVILLE, NC -- June 30, 2006 -- A new analysis of the TORO studies presented in an oral session at the 15th International HIV Drug ... DG News

Roche and Trimeris Withdraw Device Application  -  Oct 5, 2007
The companies said patients who are administering Fuzeon (enfuvirtide) with the device through an existing program or clinical trial may continue to do so, ... FDA news - FDA news (subscription)

Data Indicates Tanox HIV Drug Candidate Active In Vitro Against CCR5 ...  -  Dec 17, 2005
These data support the use of TNX-355 and enfuvirtide together in the clinical setting. Because HIV must be treated with combination therapy, ... Free with registration - PR Newswire - AccessMyLibrary.com

Physician Attitudes and Beliefs Affect Prescribing Patterns of...  -  Apr 5, 2006
In this study, interviews about the use of enfuvirtide and perceptions ... Group 2, representing 41%, had prescribed enfuvirtide in fewer than 5 patients. ... DG News

Newest HIV drugs should be used with FUZEON(R)  -  Jul 27, 2005
Data presented at IAS build a compelling case for FUZEON (enfuvirtide, formerly known as T-20) to be combined with the newest drugs to give patients facing ... i-newswire.com

Results of TNX-355 Combination Study Published in Antimicrobial...  -  May 31, 2006
This in vitro activity supports the potential for using TNX-355 and enfuvirtide together in the clinical setting and indicates that co- administration of ... RedOrbit

enfuvirtide Roche marketed, Australia (HIV infection).(Pharmaceutical...  -  Mar 14, 2005
During December 2004, Roche launched enfuvirtide (FUZEON), a fusion inhibitor, in Australia ... enfuvirtide, pentafuside, T 20, DP 178, R 698, FUZEON, J5C9, ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Efficacy of TMC114/r in Treatment-Experienced HIV Patients: Presented...  -  Apr 4, 2006
However, when enfuvirtide was assessed separately, the greatest benefit from the addition of this entry inhibitor was in those patients who were not ... DG News

… 2005 Financial Results; FUZEON(R) (Enfuvirtide) Posts Strong...  -  Jul 19, 2005
MORRISVILLE, NC -- Trimeris, Inc. (NASDAQ: TRMS) today announced the first profitable quarter for the collaboration with Roche. This positive result was ... $4.95 - Business Wire - ECNext

CORRECTION: IAS HIV treatment guidelines.  -  Sep 4, 2006
However, the guidelines actually state that, "if several potent drugs other than enfuvirtide are available, it may be best to defer enfuvirtide use until it ... $4.95 - Pharma Marketletter - ECNext

Data on New Options to Improve FUZEON Self-Injection Presented at …  -  Jul 25, 2005
..."These new studies show that administering enfuvirtide with a needle-free device or short, small- gauge needle/syringe may be a viable alternative for ... $4.95 - PR Newswire - ECNext

Updated HIV/AIDS guidelines support use of Fuzeon plus protease …  -  Oct 24, 2005
...support the use of Roche and Trimeris' Fuzeon (enfuvirtide) with an active boosted protease inhibitor in patients with three class virologic failure, ... $4.95 - Pharma Marketletter - ECNext

Fuzeon (enfuvirtide, T-20)  -  Mar 1, 2008
Fuzeon es un inhibidor de la fusión fabricado por Trimeris and Hoffmann-La Roche. La Administración de Alimentos y Fármacos de los Estados Unidos (FDA) lo ... AIDSmeds.com HIV/AIDS Treatment News

Fuzeon Plus Active Protease Inhibitor Shows Maximal HIV Suppression  -  Mar 3, 2005
...treatment strategy for treatment-experienced patients -- building upon findings from the Fuzeon (enfuvirtide) pivotal trials, TORO-1 and TORO-2. ... Pay-Per-View - FDAnews Drug Pipeline Alert - Factiva, from Dow Jones

Should We Now Adopt the HIV-RNA < 50 Copy Endpoint for Clinical …  -  Aug 17, 2007
All patients also received an OBR of at least two nucleoside reverse transcriptase inhibitors (NRTI) with or without enfuvirtide. Only data from the 131 ... Medscape

HIV Patients Resistant to Non-Nucleoside Reverse Transcriptase …  -  Aug 10, 2008
..."Patients in the etravirine group consistently achieved higher response rates than those in the placebo group, irrespective of enfuvirtide use, race, ... DG News

HIV: Kombination aus Darunavir/r und Enfuvirtide  -  Feb 21, 2007
Die heutige bedingte Zulassung zur Vermarktung des neuen Proteaseinhibitors (PI) Darunavir (geboostert durch Ritonavir) in der Europäischen Union bietet ... journalmed.de

HIV/AIDS Therapy; New findings in the area of HIV/AIDS therapy …  -  Feb 28, 2005
Study 3: Enfuvirtide long-term HIV therapy has few side effects. "The peptidic antiretroviral enfuvirtide (Fuzeon) is the first clinically approved ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

New York Blood Center; New findings in the area of HIV/AIDS therapy …  -  Mar 2, 2005
Study 3: Enfuvirtide long-term HIV therapy has few side effects. "The peptidic antiretroviral enfuvirtide (Fuzeon) is the first clinically approved ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Article: Two new anti-HIV drugs provide effective combo.(Infectious …  -  Feb 1, 2005
After enfuvirtide, an HIV-fusion inhibitor that's administered as a subcutaneous ... "Finding the right time to pull the trigger and use enfuvirtide is a ... Pay-Per-View - Family Practice News - HighBeam Research

Darunavir/ritonavir superior virologically and immunologically to …  -  Aug 15, 2006
Darunavir-treated patients who were naive to enfuvirtide had a significantly greater viral load reduction if they included enfuvirtide in their background ... Aidsmap

HN82 Trials met tipranavir  -  Jul 10, 2007
..."Roche heeft vandaag aangekondigd dat ze het nog in onderzoek zijnde middel Fuzeon (enfuvirtide, voorheen T-20 genoemd) beschikbaar stelt in de landen van ... Hiv Vereniging Nederland

Press Release: Positive Pre-Clinical Data on Two New Investigational ...  -  Feb 9, 2006
Roche and Trimeris today announced that FUZEON(R) (enfuvirtide), ... Eighty percent of patients receiving a FUZEON (enfuvirtide)-based anti-HIV drug ... Pay-Per-View - PR Newswire - HighBeam Research

Article: The price of Fuzeon resistance.(12th Retrovirus Conference …  -  Apr 1, 2005
Roche and Trimeris today announced that FUZEON(R) (enfuvirtide), ... Eighty percent of patients receiving a FUZEON (enfuvirtide)-based anti-HIV drug ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

Door Hiv Vereniging Nederland  -  Jul 10, 2007
Voor T-20 is nu ook een echte naam bedacht: enfuvirtide, tot verbazing van velen, omdat sinds 1996 ook al de naam Pentafuside voor T-20 in omloop is. Hiv Vereniging Nederland

FDA Safety Labeling Changes: Doxil, Concerta, and Fuzeon  -  Jan 12, 2005
In phase 3 clinical trials, 98% of patients receiving enfuvirtide experienced at ... Enfuvirtide use has also been associated with systemic hypersensitivity ... Medscape

Enfuvirtide associato ad un inibitore della proteasi e con Ritonavir...  -  Mar 3, 2006
Venerdì 3 Marzo 2006 - Fuzeon ( Enfuvirtide ) è il primo e solo inibitore della fusione per il trattamento dell'infezione da HIV. ... XagenaSalute

HIV/AIDS; Reports from Spain and the United Kingdom add new data to …  -  May 17, 2006
Study 3: Genotypic and phenotypic resistance to enfuvirtide rapidly ... According to recent research from Spain, "Enfuvirtide (ENF) is the first of a novel ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Progress in Treating HIV Infection: State-of-the Art Issues and...  -  Aug 31, 2005
Adding enfuvirtide (ENF) to a new ritonavir-boosted protease inhibitor (PI) increases the response in triple-class-experienced patients. ... Medscape

ICAAC: TMC114 shows further promise in second POWER study  -  Jan 6, 2006
Use alongside enfuvirtide (T-20) and/or a lower number of primary protease ... When analysed by baseline characteristics, enfuvirtide in the background ... Aidsmap

HIV Clinical Trial Design for Antiretroviral Development: Treatment- …  -  Jun 29, 2008
Since the studies of enfuvirtide, week 24 optimized background virologic response rates in placebo groups increased from 9% (enfuvirtide studies) to greater ... Medscape

T-20 increases tipranavir levels but does not increase risk of liver...  -  Sep 12, 2007
Taking T-20 (enfuvirtide, Fuzeon) with tipranavir (Aptivus) boosted by ritonavir ... Combined tipranavir and enfuvirtide use associated with higher plasma ... Aidsmap

Tipranavir for HIV Infection  -  Jul 1, 2005
Addition of enfuvirtide to both TPV/r and CPI/r resulted in greater treatment ... Consideration should be given to including enfuvirtide as part of the ... Pay-Per-View - Infectious Disease Alert - Factiva, from Dow Jones

Press Release: Updated HIV/AIDS Treatment Guidelines Support Use of …  -  Oct 13, 2005
HIV drugs, FUZEON(R) (enfuvirtide ... treatment-experienced patients living with ... initiate FUZEON-based therapy ... treatment-experienced patients or ... Pay-Per-View - PR Newswire - HighBeam Research

Darunavir looking promising as companion for agents in new HIV drug …  -  Apr 5, 2007
In the POWER 1 & 2 studies individuals who had no prior exposure to the fusion inhibitor enfuvirtide (Fuzeon), and who included the drug in their optimised ... Aidsmap

Boehringer Ingelheim Announces 48-Week Results from Aptivus(R) ( …  -  Nov 21, 2005
23.9% of patients taking a CPI/r with enfuvirtide. The median time to treatment failure with the addition of enfuvirtide was 337 days for the APTIVUS/r ... Free with registration - PR Newswire - AccessMyLibrary.com

The Lancet Publishes 48-week Results From Tipranavir RESIST Studies …  -  Aug 8, 2006
Enfuvirtide-naïve patients receiving enfuvirtide with Aptivus® achieved increases in treatment response to 58.5% vs. 21.6% of enfuvirtide-naïve patients ... DG News

Tipranavir and ART-Experienced Patients  -  Apr 11, 2005
The use of enfuvirtide was allowed, if chosen prior to randomization. ... Further, it should be noted that among patients who received enfuvirtide and ... Medscape

XIV International HIV Drug Resistance Workshop: Entry inhibitors  -  Jun 22, 2005
Further data from GSK suggested that their R5 antagonist (873140), currently in Phase 2/3 trials retains efficacy against enfuvirtide-resistant virus and ... Aidsmap

T-20 fails to prevent mother-to-child transmission: case report  -  Jun 13, 2005
..."Theoretically," they write, "ongoing viral replication of the multidrug-resistant, enfuvirtide-susceptible virus may have occurred within the genital ... Aidsmap

Panacos finds oral fusion inhibitors, provides development update on ...  -  Aug 30, 2006
Meanwhile Roche and Trimeris, the partners who developed enfuvirtide, continue to search for easier-to-take peptide fusion inhibitors. ... Aidsmap

HHS issues updated HIV guidelines.(Health &amp; Human Services)( …  -  Nov 21, 2005
Enfuvirtide is currently administered subcutaneously, but a needleless system ... The Biojector version of enfuvirtide is expected to be better received and ... Free with registration - Drug Topics - AccessMyLibrary.com

Tipranavir/Ritonavir Combination Continues to Show Superiority Over …  -  Sep 30, 2006
Among the patients overall, 20% took enfuvirtide. ... Among those on enfuvirtide, 38.2% of those on boosted tipranavir achieved a viral load of < 400 ... DG News

HIV/AIDS Therapy; HIV fusion inhibitors have been developed to battle...  -  Jan 2, 2006
..."In 2003, the FDA and EMEA approved enfuvirtide (Fuzeon), a 36-amino-acid peptide derived from the natural gp41 HR2 sequence, as the first HIV fusion ... Pay-Per-View - AIDS Weekly - Factiva, from Dow Jones

Press Release: Roche and Trimeris Announce Selection of Two Next …  -  Jan 17, 2006
Roche and Trimeris currently market FUZEON(R) (enfuvirtide), the first and ... July 11 /PRNewswire/ -- Fuzeon(R) (enfuvirtide), the first and only fusion ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Roche and Trimeris Announce FDA Filing of FUZEON(R) …  -  Jul 18, 2005
Drug Application (NDA) for FUZEON(TM) (generic: enfuvirtide ... other antiretroviral agents, FUZEON is the most clinically advanced ... month review period ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: FDA Issues Approvable Letter in Response to Application...  -  Nov 23, 2005
Roche and Trimeris today announced that FUZEON(R) (enfuvirtide), the first and ... afford enhanced and simplified access to FUZEON for patients and their ... Pay-Per-View - PR Newswire - HighBeam Research

Tipranavir (Aptivus): approval cautiously recommended.  -  May 27, 2005
Combination with Fuzeon (enfuvirtide): Tipranavir worked much better in ... They also had little or no enfuvirtide resistance because this drug is in a ... $4.95 - AIDS Treatment News - ECNext

Analysis: AIDS pipeline bursting  -  Jul 24, 2007
These fusion inhibitors differ from enfuvirtide -- sold by Roche as Fuzeon -- now a mainstay among patients who have used numerous antiretroviral drugs ... United Press International

Updated HIV/AIDS Treatment Guidelines Support Use of Fuzeon Plus an …  -  Oct 13, 2005
...(DHHS) support the use of Fuzeon® (enfuvirtide) with an active boosted protease ... PI and enfuvirtide), the goal of therapy is suppression of viremia. ... DG News

MK-0518: three-quarters of highly treated patients have undetectable...  -  Sep 30, 2006
Use of enfuvirtide improved treatment efficacy in all arms, with about 90% of those taking MK-0518 achieving viral loads below 400 copies/ml. ... Aidsmap

Long-Term Data Show Aptivus(R) (tipranavir) Continues to Outperform …  -  Nov 15, 2006
1) - Patients taking tipranavir/r combined with first-time enfuvirtide use achieved a greater mean change from baseline (-2.00 log10 copies/mL vs. ... ots.at

Literature Commentary by Dr. John G. Bartlett : ARV Resistance  -  Aug 6, 2007
The enfuvirtide was discontinued and the CD4 cell count and viral load were measured on at least 6 occasions during the subsequent 4 weeks. ... Medscape

IAS: Maraviroc produces best results when combined with another...  -  Aug 14, 2007
These were enfuvirtide (Fuzeon), lopinavir/ritonavir (Kaletra), tipranavir (Aptivus), fosamprenavir (Telzir) or atazanavir (Reyataz). ... Aidsmap

This antiviral offers new option to HIV patients.(NEW DRUG)  -  Aug 7, 2006
The new PI also appears to work best when given in combination with the fusion inhibitor Fuzeon (enfuvirtide, Roche). In pivotal clinical studies, ... Free with registration - Drug Topics - AccessMyLibrary.com

Merck's ISENTRESS® Tablets In Combination With Other Anti HIV …  -  Feb 11, 2008
...raltegravir plus OBT were diarrhea, nausea, vomiting, fatigue, injection site pain or reaction (due to enfuvirtide), joint pain, headache and itching. ... Medical News Today - Medical News Today (press release)

New Interim Results Demonstrate High Response Rate With FUZEON(R) …  -  Jul 20, 2007
..."Previous studies had provided encouraging -- but limited -- information on the use of enfuvirtide in combination with darunavir/r," said Edwin DeJesus, MD, ... $4.95 - PR Newswire - ECNext

Maraviroc raises CD4 counts in patients with mixed-tropism virus, may...  -  Aug 18, 2006
A trend towards a greater viral load decrease in maraviroc-treated patients was evident among those who also received enfuvirtide, where viral load fell by ... Aidsmap

Guidelines Updated on Managing Drug Interactions With HIV-Related TB  -  Feb 6, 2008
...not interact significantly with the rifamycins: the nucleoside analogues (other than zidovudine) and enfuvirtide, which is a parenteral entry inhibitor. ... Medscape

Press Release: New Data Presented at Major AIDS Meeting Show …  -  Mar 1, 2005
HIV drugs, FUZEON(R) (enfuvirtide ... treatment-experienced patients living with ... initiate FUZEON-based therapy ... treatment-experienced patients or ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: New Data Show Two-Thirds of Patients Achieve …  -  Dec 19, 2005
HIV drugs, FUZEON(R) (enfuvirtide ... treatment-experienced patients living with ... initiate FUZEON-based therapy ... treatment-experienced patients or ... Pay-Per-View - PR Newswire - HighBeam Research

Positive Opinion in Europe for Tipranavir  -  Jul 28, 2005
...(4) The majority of patients (70%) who had never taken enfuvirtide before and who combined the drug with APTIVUS/r, achieved a predefined treatment response ... Pay-Per-View - ots - Originaltextservice Switzerland - Factiva, from Dow Jones

Cancer Research; Results of TNX-355 combination study published in …  -  Jun 27, 2006
This in vitro activity supports the potential for using TNX-355 and enfuvirtide together in the clinical setting and indicates that coadministration of ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Press Release: Roche and Trimeris Announce Selection of Two Next …  -  Jan 19, 2006
FUZEON(R) (enfuvirtide), co-developed by Roche and Trimeris (Nasdaq: TRMS) and ... The study was conceived to look at attitudes to FUZEON (enfuvirtide), ... Pay-Per-View - PR Newswire Europe - HighBeam Research

HIV/AIDS Research; CHMP offers positive opinion in Europe for …  -  Aug 24, 2005
The majority of patients (70%) who had never taken enfuvirtide before and who combined the drug with APTIVUS/r, achieved a predefined treatment response, ... Pay-Per-View - Vaccine Weekly - Factiva, from Dow Jones

Press Release: European Approval of HIV Drug darunavir Will Provide a...  -  Feb 16, 2007
PRNewswire/ -- Today, HIV drug Fuzeon (enfuvirtide or T ... class of antiretroviral HIV drugs to emerge in the last eight years. ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Industry warily eyes new Medicare drug plan  -  Feb 7, 2006
In addition, it singled out two biotech medicines, Fuzeon (enfuvirtide) and Iressa (gefitinib), as exempt from the rule, explaining that the exclusions were ... Nature.com

Kaiser Permanente Clinical Trials Patients Celebrate World AIDS Day …  -  Nov 26, 2008
This study examined patients changing from enfuvirtide, an HIV medication given by subcutaneous injection that can leave patients with painful nodules at ... International Business Times

Tipranavir nel trattamento dei pazienti adulti con resistenza...  -  Nov 18, 2005
La maggioranza dei pazienti ( 70% ), che non avevano mai ricevuto Enfuvirtide prima, e che sono stati trattati aggiungendo alla combinazione ... XagenaSalute

Article: University of Tokyo explores new fusion approach. - Fusion...  -  Mar 1, 2006
Article: Enfuvirtide is new fusion inhibitor for HIV ... ... NewsRx.com & NewsRx.net) -- Enfuvirtide is a new fusion inhibitor for treatment of human ... Pay-Per-View - Fusion Power Report - HighBeam Research

Brand Names/Synonyms:
Enfuvirtide is also known by the following brand names and/or synonymsEnvelope polyprotein GP160 precursor [Contains: Exterior membrane glycoprotein;GP120; Transmembrane glycoprotein;GP41]; Fuzeon (Roche Pharmaceuticals)

Drug Category:
Enfuvirtide is categorized under the following by the FDA: Anti-HIV Agents

Dosage Forms:
Not Available

Absorption:
Not Available

Interactions:
Not Available



Chemical IUPAC Name:
YTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWF





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