Epivir

This page contains recent news articles, when available, and an overview of Epivir but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Epivir
(when available)

Pharmacology and use:
Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). Lamivudine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated. For the treatment of HIV infection and chronic hepatitis B (HBV)

Mechanism Of Action:
Lamivudine is a synthetic nucleoside analogue and is phosphorylated intracellularly to its active 5'-triphosphate metabolite, lamivudine triphosphate (L-TP). This nucleoside analogue is incorporated into viral DNA by HIV reverse transcriptase and HBV polymerase, resulting in DNA chain termination.

News Articles on Lamivudine

Study Identifies Viread And Emtriva As The Preferred Initial Treatment For HIV ...  -  ‎Dec 10, 2009‎
This Phase 3 trial, known as study A5202, compared the efficacy and safety of two NRTI combinations, Viread and Emtriva versus Ziagen and Epivir, ... The AIDS Beacon (blog)

GlaxoSmithKline, Pfizer Formally Launch Company To Develop New HIV Treatments  -  ‎Nov 3, 2009‎
..."GSK was at the forefront of breakthroughs in HIV and AIDS treatments in the late 1980s and 1990s with anti-virals such as Retrovir, Epivir and Combivir, ... Kaiser Family Foundation

Generic Name: Tenofovir, emtricitabine  -  ‎Nov 11, 2009‎
Do not take Truvada if you are already taking Atripla, Combivir (lamivudine/zidovudine), Emtriva, Epivir or Epivir-HBV (lamivudine), Epzicom (abacavir ... Pattaya Daily News

Epzicom Associated With More Side Effects In HIV/AIDS Patients Than Truvada  -  ‎Nov 9, 2009‎
Alternatively, Epzicom is a combination therapy that contains Ziagen (abacavir) and Epivir (lamivudine). Viread and Ziagen were originally introduced to ... The AIDS Beacon (blog)

Glaxo-Pfizer tie-up opens new era in Aids battle  -  ‎Oct 31, 2009‎
GSK was at the forefront of breakthroughs in HIV and Aids treatments in the late 1980s and 1990s with anti-virals such as Retrovir, Epivir and Combivir, ... Telegraph.co.uk

è¼?瑞+葛蘭素å?²å…‹ 抗愛滋  -  ‎Nov 1, 2009‎
...葛蘭素å?²å…‹åœ¨1980年代與1990年代末期研發出立妥å¨?(Retrovir)ã€?速汰滋(Epivir)與å?¡è²?滋(Combivir)等藥物,å?¯æœ‰æ•ˆæ¸›ç·©ç—…狀,被喻為å°?抗愛滋病與HIV病毒的é‡?大çª?ç ´ ... 聯合新聞網

Glaxo und Pfizer gründen Joint Venture  -  ‎Nov 3, 2009‎
GSK steuert die Kombinationsmittel Combivir, Kivexa, und Trizivir sowie die Monopräparate Epivir, Telzir, Retrovir ud Ziagen bei. ... apotheke-adhoc

´El sida es una enfermedad muy oportunista y cualquier pulmonía me habría ...  -  ‎Oct 20, 2009‎
Empecé tomando un combinado triple de fármacos, Zerit, Epivir y Susdiva. Pero hoy en día han mejorado mucho las cosas. Ahora sólo tomo una pastilla que ... Diario de Mallorca

GSK poised to act against illegal diversion of AIDS drugs  -  May 23, 2005
...including packaging, labelling and a red coating on the Combivir and Epivir antiretroviral tablets it supplies at cost to the poorest countries. ... Forbes

Baraclude Trumps Epivir as HBV Therapy  -  Mar 8, 2006
By Neil Osterweil, Senior Associate Editor, MedPage Today. TAINAN, Taiwan, March 8 - In patients with hepatitis B infections, two international studies ... MedPage Today

Aids drugs to Africa rebranded in drive to beat racket  -  Feb 21, 2005
The company is preparing to switch to new versions of Combivir and Epivir, the antiretroviral pills, to ensure that drugs supplied at cost to Africa under a ... Times Online

Epivir.(Drug overview)  -  Jan 22, 2007
Epivir is one of the drugs used to fight infection with the human immunodeficiency virus (HIV), the deadly cause of AIDS. Doctors turn to Epivir as the ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Avexa Says Drug Reduced HIV in 48-Week Patient Study  -  Mar 12, 2008
The study compared ATC with Epivir in about 50 patients in Australia and Argentina who were resistant to the Glaxo drug. For the first 24 weeks, ... Bloomberg

AASLD: Tyzeka Bests Epivir at HBV Control at Two Years  -  Oct 30, 2006
By Neil Osterweil, Senior Associate Editor, MedPage Today. BOSTON, Oct. 30 -- Tyzeka (telbivudine) was superior to Epivir (lamivudine) at reducing hepatitis ... MedPage Today

Pegasys Tops Epivir For HBV  -  Jul 14, 2005
...by John C. Martin. A new, large clinical trial of people with a common form of hepatitis B (HBV) has found that therapy with Pegasys (peginterferon alfa-2a) ... Hepatitis Neighborhood

Business News Glaxo backs Russian HIV/Aids crusade  -  Sep 16, 2006
Glaxo will supply more than 90000 treatment packs of its drugs - Combivir, Epivir and Ziagen - to the Russian Government by the end of 2006. ... WalesOnline

Hepatitis warnings with Epivir.(be careful about abruptly stopping...  -  Apr 1, 2005
Hepatitis warnings with Epivir.(be careful about abruptly stopping your needs)(Advertisement) ... find HIV Treatment: ALERTS! articles. Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

The Hindu Business Line  -  Nov 8, 2005
According to the company, Lamivudine oral solution 10mg/ml is the first generic version approval of GlaxoSmithKline's oral solution `Epivir'. ... Hindu Business Line

AASLD: Hepatitis B Yields More to Telbivudine than Epivir  -  Nov 15, 2005
By Neil Osterweil, Senior Associate Editor, MedPage Today. SAN FRANCISCO, Nov. 15 - In patients with chronic hepatitis B infection, ... MedPage Today

Antiviral Curbs HBV in Liver Cancer During Chemotherapy  -  Feb 2, 2006
2 - Preemptive treatment with the antiviral Epivir (lamivudine) prevents ... Consider preemptive treatment with Epivir to prevent clinical hepatitis due to ... MedPage Today

Entecavir Boosts Hepatitis B Response After Lamivudine Failure  -  Jul 1, 2008
TORONTO, July 1 -- Patients who were lamivudine (Epivir) refractory saw improved hepatitis B suppression that lasted through almost two years of treatment ... MedPage Today

Cipla will make AIDS drug for kids  -  Aug 15, 2007
GlaxoSmithKline's Epivir (or lamivudine) and Bristol-Myers Squibb's Zerit (or stavudine) - all anti-retrovirals or drugs that fight AIDS. ... Daily News & Analysis

Evidence Backs New Treatments for Hepatitis B  -  Jun 29, 2005
The adverse event rate was 4% in the Pegasys plus placebo arm and 6% in the Pegasys plus Epivir arm, versus 2% in the Epivir monotherapy group, ... MedPage Today

New hepatitis drug much more effective  -  Mar 9, 2006
Among the patients who were treated with Epivir, known generically as lamivudine, only 62 percent of the 314 patients improved in the same time. ... News-Medical.net

Merck's Isentress Could Hold Promise for Several Patient Populations  -  Feb 15, 2008
An ongoing Phase II study in treatment-naive patients is comparing Isentress in combination with Viread (tenofovir disoproxil fumarate) and Epivir ... FDA news - FDA news (subscription)

BMS: Hepatitis B Drug Holds Promise  -  Mar 26, 2008
However, patients who had resistance to lamivudine, the active ingredient in GlaxoSmithKline's hepatitis B drug Epivir, were more likely to develop ... FDA news - FDA news (subscription)

B-MS' Baraclude "will dominate" hep B mart.  -  Apr 23, 2007
...the other therapies currently on the market, and the agent is less prone to viral resistance than GlaxoSmithKline's Epivir (lamivudine)," she noted. ... $9.94 - Pharma Marketletter - Alacra Store

Hepatitis warnings with Epivir.(be careful about abruptly stopping...  -  Apr 1, 2005
New precautions have been added to the labeling for Epivir (3TC), Combivir (Epivir + Retrovir), Trizivir (Epivir + Ziagen + Retrovir), and Epzicom (Epivir + ... $4.95 - HIV Treatment: ALERTS! - ECNext

GSK to sell cut price HIV/Aids drugs to Russia  -  Sep 15, 2006
More than 90000 treatment packs of the anti-retroviral treatments Combivir, Epivir and Ziagen will be supplied to Russia by the end of this year. ... Hays Pharma

Patient Satisfaction With Once-Daily Dosing Of HIV Fixed-Dose …  -  Jul 27, 2005
Multiple clinical trials have studied the use of EPIVIR and ZIAGEN in more than ... EPIVIR (a medicine in EPZICOM) in combination with other antiretroviral ... $4.95 - PR Newswire - ECNext

Apricitabine Useful for Drug-Resistant HIV  -  Mar 20, 2007
AVX-201 is a randomized study of two doses of apricitabine (600 mg or 800 mg twice daily) compared to Epivir (150 mg twice daily) in treatment-experienced ... AIDSmeds.com HIV/AIDS Treatment News

Restoration of CD4 T-cells limited in children starting HIV treatment...  -  Mar 2, 2006
Zerit) and 3TC (lamivudine, Epivir). The protease inhibitors taken by most children were nelfinavir (Viracept) and ritonavir (Norvir). ... Aidsmap

Liver transplantation can be successful in patients co-infected with...  -  May 4, 2006
...even if they are resistant to 3TC (lamivudine, Epivir / Zeffix). The study's findings were published in the May edition of Liver Transplantation. ... Aidsmap

TRIZIVIR, First Tablet to Combine Three Medications for HIV, Receives...  -  May 16, 2005
TRIZIVIR is a fixed-dose- combination tablet containing the three nucleoside reverse transcriptase inhibitors EPIVIR(R) (lamivudine, 3TC), RETROVIR(R) ... RedOrbit

Ribavirin (Systemic).  -  Feb 1, 2006
Lamivudine (eg, Epivir) or Stavudine (eg, Zerit) or Zidovudine (eg, Retrovir) -- These medicines should not be used at the same time as ribavirin. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Appro of Bristol-Myers Squibb's Baraclude recommended by FDA …  -  Mar 21, 2005
The trials were designed to compare the agent with the most commonly-used oral antiviral therapy in the USA, UK drugmaker GlaxoSmithKline's Epivir ... $4.95 - Pharma Marketletter - ECNext

Epivir (lamivudine, 3TC)  -  Jun 10, 2008
Epivir es un medicamento anti-VIH que pertenece a la categoría de los inhibidores nucleósidos de la transcriptasa reversa (INTR). Epivir evita que el VIH ... AIDSmeds.com HIV/AIDS Treatment News

Dealing with liver disease.(Disease/Disorder overview)  -  Dec 1, 2005
Chronic hepatitis B can also be treated with Epivir-HBV, a low-dose form of the HIV drug lamivudine. In cirrhosis, liver cells are damaged and replaced by ... Free with registration - PDR Family Guide to Prescription Drugs... - AccessMyLibrary.com

Tenofovir doesn't harm growth of kids' bones, suggests small study  -  Nov 29, 2005
All switched from a stable antiretroviral treatment regimen consisting of 3TC (lamivudine, Epivir), d4T (stavudine, Zerit) and a protease inhibitor to a ... Aidsmap

Patient satisfaction with once-daily dosing of HIV fixed-dose...  -  Aug 1, 2005
Multiple clinical trials have studied the use of EPIVIR and ZIAGEN in more than 5800 patients ... EPIVIR ( a medicine in EPZICOM ) in combination with other ... i-newswire.com

Natural Mutation Confers Drug Resistance on HBV  -  Apr 26, 2006
Be aware that patients with Epivir (lamivudine)-resistant HBV infections who do not respond to Hepsera (adefovir) may have a naturally occurring mutation ... MedPage Today

Combivir (zidovudine + lamivudine)  -  Mar 1, 2008
Combivir no debería ser más o menos eficaz que Retrovir y Epivir juntos. ... de Retrovir y Epivir, para obtener información sobre la posible resistencia al ... AIDSmeds.com HIV/AIDS Treatment News

Raltegravir y tenofovir reducen la carga viral hasta niveles indetecta...  -  Jul 25, 2007
...combinado con tenofovir (Viread), y raltegravir combinado con lamivudina (Epivir), incrementan los linfocitos CD4 y reducen la viremia hasta "cifras ... doyma.es

FDA clears B-MS' Baraclude for hep B.(Bristol-Myers Squibb Ltd.'s …  -  Apr 11, 2005
The agent surpassed its competitor, UK drugmaker GlaxoSmithKline's Epivir (lamivudine), in suppressing HBV. "With the approval of Baraclude, B-MS will now ... Pay-Per-View - Pharma Marketletter - Factiva, from Dow Jones

Truvada (tenofovir + emtricitabine)  -  Mar 1, 2008
Truvada no debería tomarse junto con Epivir, ni con otra combinación de tabletas que contengan Epivir (por ejemplo: Epzicom, Combivir o Trizivir). ... AIDSmeds.com HIV/AIDS Treatment News

FDA Alert on Viramune Won't Impact Sales, Boehringer Says  -  Jan 28, 2005
Viramune is a component of a commonly used triple combination HIV cocktail that also consists of GlaxoSmithKline's Epivir (lamivudine) and Bristol-Myers ... Pay-Per-View - Washington Drug Letter - Factiva, from Dow Jones

Update to HIV treatment guidelines.(Treatment News)(Brief Article)  -  Apr 1, 2005
The combination of Viread and either Epivir (3TC) or Emtriva (FTC) is now recommended as a 2-nuke backbone for regimens based on either a non-nucleoside ... $4.95 - HIV Treatment: ALERTS! - ECNext

Development of NRTI Reverset Halted  -  Apr 4, 2006
Approximately 70% of patients in Study 901 were on regimens containing either Epivir or Emtriva. After the results of Study 203 demonstrated that the ... AIDSmeds.com HIV/AIDS Treatment News

Epzicom (abacavir + lamivudine)  -  Aug 17, 2007
La marca comercial "Epzicom" es un acrónimo de EPivir y ZIagen COMbinados. La combinación en tableta de Ziagen y Epivir se vende en la unión Europea, ... AIDSmeds.com HIV/AIDS Treatment News

San José, Costa Rica.  -  Mar 10, 2006
Entre las personas tratadas con Epivir, solo el 62% de un grupo de 314 logró mejoras en el mismo tiempo que el otro fármaco. ... La Nación Costa Rica

Unravelling HIV treatment: Southern Africa has been bearing the brunt...  -  Apr 23, 2007
GSK's Combivir (Retrovir + Epivir), Trizivir (Retrovir + Epivir + Ziagen), the once-daily version Epivir (3TC), and Epzicom (Epivir + Ziagen) now comprise a ... Free with registration - Chemistry and Industry - AccessMyLibrary.com

Sustiva drug interactions.(FDA BITS) | Article from HIV Treatment: …  -  Jun 1, 2007
Right now, I am on Videx, Epivir, and Sustiva. I get bad leg cramps pretty frequently and sometimes feel ... classes: either a boosted protease inhibitor ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

Age-dependent Pharmacokinetics of Lamivudine in HIV-infected Children  -  Oct 15, 2006
Lamivudine (3TC, Epivir ® ) has been licensed for the treatment of human ... The Epivir ® Prescribing Information states that "total exposure to lamivudine, ... Nature.com

Study Finds Viread Advantages in Black Patients  -  Mar 9, 2007
In study 934, antiretroviral-naïve patients took Sustiva plus Combivir® (Retrovir plus Epivir) or Viread plus Emtriva (now available as Truvada® or, ... AIDSmeds.com HIV/AIDS Treatment News

Aprueba EU fármaco genérico contra el Sida .  -  Nov 4, 2005
...de India, y que sirve como el equivalente genérico de "Epivir" para tratar la infección del virus de inmunodeficiencia humana (VIH). ... El Universal - El Universal (México)

Calidad de vida - eluniversal.com  -  Nov 6, 2005
Aurobindo Pharma LTD, de India, y que sirve como el equivalente genérico de Epivir para tratar la infección del virus de inmunodeficiencia humana (VIH). ... El Universal - El Universal (Venezuela)

Pegylated Interferon/Lamivudine Combo Tested as HBV Therapy  -  Jan 19, 2005
So, they tested PEG Intron with Epivir-HBV in this trial in hopes of boosting the treatment's effectiveness. Each patient in the study was assigned at ... Hepatitis Neighborhood

Combivir.(Used to fight the human immunodeficiency virus )(Drug …  -  Dec 1, 2005
You should not take Combivir if either component, Epivir or Retrovir, ... The Epivir component of Combivir is not recommended in people with low body weight ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Baraclude Induces HIV Drug Resistance  -  Mar 5, 2007
For example, Viread® (tenofovir), Emtriva® (emtricitabine), and Epivir® (lamivudine) are believed to be highly effective against HBV, although Epivir is the ... AIDSmeds.com HIV/AIDS Treatment News

How is it treated?  -  Mar 12, 2007
Lamivudine (Epivir, Epivir-HBV): After being approved for the treatment of HIV ... If the person has taken Epivir or Emtriva in the past—and has HBV that is ... AIDSmeds.com HIV/AIDS Treatment News

RSC-GlaxoSmihKline destina 558 millones de euros en 2005 a ayudas a …  -  May 17, 2006
La compañía con sede en Reino Unido envió además a precios preferenciales 126 millones de comprimidos de 'Combivir' y 'Epivir' como tratamientos ... elEconomista.es

KIVEXA®, UN SÓLO COMPRIMIDO UNA VEZ AL DÃ?A SIMPLIFICA EL …  -  Mar 16, 2005
La satisfacción de los pacientes se incrementa cuando se les cambia dentro un régimen con varios medicamentos que incluye Ziagen® + Epivir® dos veces al día ... acceso.com

Hepatitis A Medications - Hepatitis A Health Information - NY Times …  -  Dec 5, 2008
Lamivudine (Epivir-HBV) is also used in another formulation to treat human immunodeficiency virus (HIV). About 20% of patients who take lamivudine develop ... New York Times

HBV Drug Wins FDA Okay  -  Mar 23, 2005
The trials compared the drug to Epivir-HBV in more than 2300 patients with ... The first study 2 compared Baraclude with Epivir in patients with chronic ... Hepatitis Neighborhood

Hepatitis C Medications - Hepatitis C Health Information - NY Times …  -  Feb 20, 2008
Lamivudine (Epivir-HBV) is also used in another formulation to treat human immunodeficiency virus (HIV). About 20% of patients who take lamivudine develop ... New York Times

Unravelling HIV treatment: Southern Africa has been bearing the brunt...  -  Apr 23, 2007
GSK's Combivir (Retrovir + Epivir), Trizivir (Retrovir + Epivir + Ziagen), the once-daily version Epivir (3TC), and Epzicom (Epivir + Ziagen) now comprise a ... Pay-Per-View - Chemistry and Industry - HighBeam Research

Alcoholic Liver Disease Treatment - Alcoholic Liver Disease Health …  -  Dec 12, 2008
Lamivudine (Epivir or 3TC) is an antiretroviral drug that is used to treat human immunodeficiency virus (HIV) as well as hepatitis B. Studies suggest that ... New York Times

Press Release: Patient Satisfaction With Once-Daily Dosing Of HIV...  -  Jul 27, 2005
PR Newswire; June 29, 1998 ; 700+ words ... ... combination of the investigational compound Ziagen(TM) (abacavir), together with Epivir ... who completed 72 ... Pay-Per-View - PR Newswire - HighBeam Research

慢性乙è‚?28年經驗談(己治愈但ä»?æœ?å°?é‡?è‚?安能)  -  Apr 5, 2006
...慢性B�病�: 您是��天�用EPIVIR? 您�這種藥�瞭解多少?我想和大家分享我的寶貴經驗. 我從1999年1月6 日開始�用EPIVIR,託朋�從��設法尋找替代�,當時, ... udn.com

New Treatments Available for Hepatitis B  -  Oct 31, 2008
The first oral treatment, Epivir-HBV, was introduced in 1998 by GlaxoSmithKline out of the ... Side effects are also usually mild and similar to Epivir-HBV. ... AsianWeek

Chronic hepatitis can be hidden, lifelong infection: combination...  -  Nov 1, 2005
Epivir HBV, which is formulated in a lower dose, cannot be substituted for lamivudine (Epivir) in HIV treatment regimens. (4.) Optimal duration of therapy ... Free with registration - Managed Healthcare Executive - AccessMyLibrary.com

Bristol-Myers Squibb Gains on Drug OK  -  Mar 30, 2005
Many Epivir patients, for example, develop a resistance to the drug. Other HBV drugs are Intron-A from Schering-Plough (SGP - commentary - Cramer's Take) ... TheStreet.com - TheStreet.com (subscription)

HIV/AIDS Treatment; Patients more satisfied with once-daily dosing of...  -  Aug 24, 2005
The data presented at IAS are from ESS30008, a multicenter study that enrolled 260 patients with viral suppression on a regimen containing EPIVIR and ZIAGEN ... Pay-Per-View - Vaccine Weekly - Factiva, from Dow Jones

¿Es el interferón lo más indicado?  -  Apr 18, 2007
Lamivudine (Epivir, Epivir-VHB): Después de haberse aprobado para el tratamiento ... Si la persona ha tomado Epivir o Emtriva en el pasado (y tuviera un VHB ... elmundo.es

Ã?ndice de lecciones  -  May 11, 2007
En el grupo en Epivir, las cargas virales, disminuyeron en un promedio de 3 log después de las 12 semanas. Más adelante se reportarán datos adicionales de ... AIDSmeds.com HIV/AIDS Treatment News

Press Release: Stressgen Granted US Patent Covering Therapeutic …  -  Sep 7, 2005
If approved by the FDA, Epivir-HBV will be the first oral antiviral treatment ... Advisory Committee recommended that Epivir-HBV be approved for the ... Pay-Per-View - PR Newswire - HighBeam Research

Hep C Drug Approved as HBV Therapy  -  May 25, 2005
...meeting in mid-April, doctors tested the effectiveness of Pegasys plus placebo, Pegasys combined with lamivudine (Epivir-HBV) or lamivudine monotherapy. ... Hepatitis Neighborhood

GlaxoSmithKline rebrands AIDS drugs.(Packaging And Labeling)( …  -  Mar 1, 2005
GSK also has embossed Combivir and Epivir tablets and introduced unique batch numbers ... GSK has registered the red Epivir and Combivir tablets with the ... Free with registration - Pharmaceutical Technology - AccessMyLibrary.com

US Food and Drug Administration (FDA) Approves ATRIPLA(TM) ( …  -  Jul 12, 2006
ATRIPLA should not be coadministered with drugs containing lamivudine, including Combivir, Epivir(R), Epivir-HBV(R), EpzicomTM, or Trizivir(R). ... Free with registration - PR Newswire - AccessMyLibrary.com

Bloomberg Printer-Friendly Page  -  Dec 11, 2007
Epivir(R) or Epivir-HBV(R) (lamivudine), Epzicom(TM) (abacavir sulfate/lamivudine), or Trizivir(R) (abacavir sulfate/lamivudine/zidovudine). ... Bloomberg

Ranbaxy gets marketing nod for paediatric anti-retrovirals  -  Dec 7, 2007
Lamivudine is sold by GSK under the brand name Epivir and EPivir-HBV, while Stavudine is marketed by Bristol Myers Squibb under the brand name Zerit. ... Hindu Business Line

Idenix, Novartis Team on Drug  -  Jan 2, 2006
They point out that telbivudine demonstrated greater efficacy in the clinical trial conducted by Idenix and Novartis than GlaxoSmithKline's Epivir. Red Herring

Ranbaxy presents bioequivalence data on two paediatric fixed dose...  -  Aug 17, 2006
Seventeen fasting healthy adult males were given recommended paediatric doses of nevirapine (Viramune) oral suspension, lamivudine (Epivir) oral solution ... Aidsmap

Reyataz heart risks.(FDA Bits)(Food and drug administration)(Brief...  -  Apr 1, 2005
Rescriptor Agenerase Fuzeon (Epivir + Retrovir) Emtriva Sustiva Crixivan Epivir Viramune Fortovase Hivid Invirase Retrovir Kaletra Trizivir (Epivir + Lexiva ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

Press Release: TRIZIVIR, First Tablet to Combine Three Medications...  -  May 16, 2005
TRIZIVIR is a fixed-dose- combination tablet containing the three nucleoside reverse transcriptase inhibitors EPIVIR(R) (lamivudine, 3TC), RETROVIR(R) ... Pay-Per-View - PR Newswire - HighBeam Research

Lamivudine is still useful against some hepatitis B.(Gastroenterology)...  -  Oct 1, 2006
Telbivudine showed greater efficacy than lamivudine did during 2 years of treatment for ... telbivudine at 600 mg/day to that of lamivudine (Epivir) at 100 ... Pay-Per-View - Internal Medicine News - HighBeam Research

Press Release: Clinicians Expect Bristol-Myers Squibb's Baraclude Use...  -  Aug 2, 2006
..."Although clinicians expect the use of Baraclude to continue to expand at the expense of Epivir-HBV, surveyed formulary directors, at this time, ... Pay-Per-View - PR Newswire - HighBeam Research

Clinicians Expect Bristol-Myers Squibb's Baraclude Use to Increase...  -  Aug 2, 2006
..."Although clinicians expect the use of Baraclude to continue to expand at the expense of Epivir-HBV, surveyed formulary directors, at this time, ... $4.95 - PR Newswire - ECNext

Business Update; Clinicians expect Bristol-Myers Squibb's Baraclude...  -  Aug 29, 2006
..."Although clinicians expect the use of Baraclude to continue to expand at the expense of Epivir-HBV, surveyed formulary directors, at this time, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Press Release: Epidemiology Study Reports New Information on …  -  Jul 26, 2005
PR Newswire; June 29, 1998 ; 700+ words ... ... combination of the investigational compound Ziagen(TM) (abacavir), together with Epivir ... who completed 72 ... Pay-Per-View - PR Newswire - HighBeam Research

Fuzeon update.(Treatment News) | Article from HIV Treatment: ALERTS!...  -  Apr 1, 2005
Rescriptor Agenerase Fuzeon (Epivir + Retrovir) Emtriva Sustiva Crixivan Epivir Viramune Fortovase Hivid Invirase Retrovir Kaletra Trizivir (Epivir ... ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

Truvada® aura-t-il la peau de Combivir ?  -  Mar 5, 2006
En effet, Emtriva®, copie presque conforme de l'Epivir®, associée à Viread®, le nucléotidique “superstar € ? de ces trois dernières années, ... survivreausida.net

Ã?ndice de lecciones  -  Mar 24, 2006
La estructura química de Racivir es similar a la de Epivir® (3TC) y Emtriva® ... Evaluará la seguridad y eficacia del reemplazo de Epivir® (3TC) por Racivir ... AIDSmeds.com HIV/AIDS Treatment News

USPHS releases updated guidelines for management of occupational …  -  Dec 1, 2005
300 mg twice daily or 200 lamivudine (Epivir) mg three times daily, ... associated with decreased lamivudine (Epivir) risk of HIV transmission; ... $4.95 - American Family Physician - ECNext

Studies Disagree on Abacavir for Patients With High Viral Loads  -  Aug 12, 2008
Studies included in the analysis were CNA30021, evaluating once-daily Ziagen (abacavir), Epivir (lamivudine) and Sustiva (efavirenz); CNA30024, ... AIDSmeds.com HIV/AIDS Treatment News

Beckstrand v. Electronic Arts Group Long Term Disability Insurance...  -  Oct 20, 2006
He documented his current medications including Agenerase, Epivir, Zerit, ... On April 19, 2004, Beckstrand was taking Epivir, Zerit, and Sustiva, Celexa, ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

Pegasys approval.(RXs)(Brief Article) | Article from Chain Drug...  -  Jun 6, 2005
Epivir-HBV has been recommended for approval as a treatment of chronic hepatitis B. ... The company also announced that another of its products, Epivir-HBV, ... Pay-Per-View - Chain Drug Review - HighBeam Research

Gilead Sciences and Merck Establish Agreement for Distribution of …  -  Aug 11, 2006
ATRIPLA should not be coadministered with drugs containing lamivudine, including Combivir, Epivir(R), Epivir-HBV(R), Epzicom(TM), or Trizivir(R). ... Free with registration - Business Wire - AccessMyLibrary.com

Stinson v. Galaza, No. 1:00-CV-6067-OWW-DLB-P (EDCal. 01/29/2006)  -  Jan 29, 2006
In May 1999, the physician notes that plaintiff reports that he is taking his HIV anti-viral medications (which consisted of Zerit, Epivir and Nevirapine) ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

Bristol-Myers Squibb, Gilead Sciences and Merck & Co. Submit …  -  Oct 9, 2006
...should not be coadministered with drugs containing lamivudine, including Combivir([R]), Epivir([R]), Epivir-HBV([R]), Epzicom([TM]), or Trizivir([R]). ... Free with registration - Business Wire - AccessMyLibrary.com

Idenix reports Novartis exercises option to license compound for...  -  Mar 31, 2006
...found that after one year of treatment the telbivudine group showed greater anti-viral and clinical efficacy than the Epivir group. Free with registration - Transplant News - AccessMyLibrary.com

Bristol-Myers Squibb And Gilead Sciences Announce Health Canada …  -  Oct 17, 2007
Epivir(R) or Epivir-HBV(R) (lamivudine), Epzicom(TM) (abacavir sulfate/lamivudine), or Trizivir(R) (abacavir sulfate/lamivudine/zidovudine). ... $4.95 - M2 Presswire - ECNext

Wir übernehmen Verantwortung GlaxoSmithKline seit 25 Jahren führend …  -  Nov 30, 2006
Allein im Jahre 2005 lieferte GSK 45 Millionen Combivir(R)- und 81 Millionen Epivir-Tabletten zu Vorzugspreisen in die Entwicklungsländer, zumeist nach ... presseportal.de

Press Release: DiObex and Camurus Sign License Agreement for the …  -  Mar 18, 2008
...containing ZERIT extended release+SUSTIVA(R) (efavirenz)+Epivir ... immediate release+SUSTIVA+Epivir (extended release-immediate release difference ... ... Pay-Per-View - PR Newswire - HighBeam Research

ä¹™è‚?6種å?£æœ?æ–°è?¯(Ep-En-ba-Ty Cl &Vi)  -  Sep 1, 2006
...干�能�天一顆,藥費分別為110元�240元,在��尚�給付的年代,救�一年�價四 �(Epivir) {Mikkyhan's suggested dosage cost 救�一年�價2�}到八�元,而病患 ... udn.com

Bristol-Myers Squibb And Gilead Announce Data Supporting …  -  Jan 9, 2006
Truvada should not be used with Emtriva or Viread, or other drugs containing lamivudine, including Combivir®, Epivir®, Epivir-HBV®, Epzicom™ or Trizivir®. ... webwire.com

Netherlands Corporate News - Voorbereidende 24-weekse data betreft …  -  Nov 17, 2005
Truvada should not be used with Emtriva or Viread, or other drugs containing lamivudine, including Combivir, Epivir(R), Epivir-HBV(R), Epzicom(TM) or ... Netherlands Corporate News - Netherlands Corporate News (persbericht)

European CHMP Issues Positive Opinion For ATRIPLA(R) (efavirenz 600 …  -  Oct 19, 2007
Epivir(R) or Epivir-HBV(R) (lamivudine), Epzicom(TM) (abacavir sulfate/lamivudine), or Trizivir(R) (abacavir sulfate/lamivudine/zidovudine). ... Medical News Today - Medical News Today (press release)

Brand Names/Synonyms:
Epivir is also known by the following brand names and/or synonyms3TC; Combivir; DRG-0126; Epivir; Epivir-Hbv; GR 109714X; HSDB 7155; Hepitec; Heptovir; LAMIVUDINE; Lamivudine; Lamivudine [Usan:Ban:Inn]; Trizivir; Zeffix

Drug Category:
Epivir is categorized under the following by the FDA: Anti-HIV Agents; Nucleoside and Nucleotide Reverse Transcriptase Inhibitors; ATC:J05AF05

Dosage Forms:
SOLUTION; TABLET

Absorption:
Lamivudine was rapidly absorbed after oral administration in HIV-infected patients. Absolute bioavailability in adults is 86% ± 16% for the tablet and 87% ± 13% for the oral solution.

Interactions:
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Chemical IUPAC Name:
4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1H-pyrimidin-2-one





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