Epoetin alfa

This page contains recent news articles, when available, and an overview of Epoetin alfa but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Epoetin alfa
(when available)

Pharmacology and use:
Used in the treatment of anemia. Involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. For treatment of anemia (from renal transplants or certain HIV treatment)

Mechanism Of Action:
Binding of erythropoietin to the erythropoietin receptor leads to receptor dimerization, which facilitates activation of JAK-STAT signaling pathways within the cytosol. Activated STAT (signal transducers and activators of transcription) proteins are then translocated to the nucleus where they serve as transcription factors which regulate the activation of specific genes involved in cell division or differentiation.

News Articles on Epoetin alfa

Impact of Epoetin-beta on Survival and Tumor Progression Affected by Starting ...  -  05 Jan 2010
The most commonly used ESAs in the United States are Epogen® (epoetin alfa) Aranesp® (darbebpoetin). The most commonly use ESA in Europe is epoetin-beta ... Cancer Consultants

Bypass Anemia Drugs in Chronic Kidney Disease, Expert Says  -  ‎Dec 24, 2009‎
In CHOIR, epoetin-alfa (Procrit) targeted to a hemoglobin of 13.5 g/dl raised the composite rate of death, MI, heart failure, hospitalization, and stroke by ... MedPage Today

Tired of Being Tired?Cancer-related fatigue doesn't have to slow you down.  -  ‎Dec 23, 2009‎
...available at www.curetoday.com/new_blood), but erythropoiesis-stimulating agents, such as Procrit (epoetin alfa) and Aranesp (darbepoetin alfa), ... Curetoday.com (press release)

A New Look at High Hb Goals  -  ‎Dec 10, 2009‎
...a randomized trial comparing the effect of treatment with epoetin alfa to two Hb targets (11.3 and 13.5 g/L) on the composite end point of death, ... Renal and Urology News

A vörösvértest-termelés serkentése hátrányos lehet  -  ‎Dec 28, 2009‎
Az epoetin-alfa hatására magasabb lett a halálozási arány, gyakoribb lett a szívinfarktus, a szívelégtelenség, és többször volt szükség a betegek kórházba ... medicalonline.hu/

ë‚´ë…„ 제약시장 치료계열별 íŒ?ë?„ ì°¨ì?´  -  ‎Dec 9, 2009‎
...보존치료 분야ì—?ì„  'ì•„ë?¼ë„¤ìŠ¤í”„'와 '프로í?¬ë¦¬íЏ'(Procrit, epoetin alfa)는 안전성 문제로 매출ì?´ 떨어지겠지만 '뉴í?¬ê²?'(Neupogen, filgrastim)ê³¼ '뉴ë?¼ ... 디지틀보사

Aranesp, Epogen and Procrit Blood Clot Risk Confirmed: Study  -  ‎Nov 11, 2009‎
Amgen's Aranesp (darbepoetin alfa) and Epogen (Epoetin alfa) and Johnson and Johnson's Procrit (Epoetin alfa) are prescribed to patients with kidney disease ... AboutLawsuits.com

ASN: Major Anemia Trial Results Lead to Practice Changes  -  ‎Nov 3, 2009‎
The findings led the FDA to add to the labels of the ESAs epoetin-alfa (Epogen, Procrit) and darbepoetin alfa (Aranesp) a boxed warning against aggressively ... MedPage Today

Program Found to Improve Cancer-Related Insomnia However, second study finds ...  -  ‎Nov 5, 2009‎
5 (HealthDay News) -- Cancer-related insomnia can be improved by behavioral therapy but not epoetin alfa, according to two studies published online Nov. ... ModernMedicine

Anemia Drug May Raise Stroke Risk in Kidney Patients  -  ‎Oct 31, 2009‎
In earlier studies, Aranesp and a similar drug, epoetin alfa, marketed as Procrit or Epogen, were linked to increased risk of death in cancer and stroke ... U.S. News & World Report

Comparing ESA Dosing Regimens for Anemic Kidney Disease Patients  -  ‎Oct 21, 2009‎
Although the FDA-approved starting dose of epoetin alfa for the correction of anemia in patients with chronic kidney disease (CKD) is 50-100 IU/kg, ... National Anemia Action Council

Affymax and Takeda Announce Hematide Publication in the New England Journal of ...  -  ‎Nov 4, 2009‎
...human erythropoietins, such as epoetin alfa or beta and darbepoetin alfa, thus suppressing the production of red blood cells by the bone marrow. ... Reuters

Risks outweighed benefits of darbepoetin alfa in patients with type 2 diabetes ...  -  ‎Nov 3, 2009‎
...and Outcomes in Renal Insufficiency (CHOIR) trial, which studied the use of epoetin alfa treatment to achieve two different target hemoglobin levels. ... Endocrine Today

Affymax and Takeda Announce Preliminary Phase 2 Data Demonstrated That ...  -  ‎Oct 30, 2009‎
This is the first reported data from an open-label, controlled comparative study of once-monthly Hematide compared to three times per week epoetin alfa ... Reuters

Why Large Doses of IV Iron Decrease HD Patient Survival Is Unclear  -  ‎Nov 1, 2009‎
These patients were much more likely to have received very high doses of epoetin alfa. The researchers ruled out underlying bleeding conditions that ... Renal and Urology News

Outlining Drug-Induced Anemia and Select Medications  -  ‎Oct 21, 2009‎
Several studies have found that these drugs do not affect the action of epoetin alfa, and that doses and Hb levels are similar among treated and control ... National Anemia Action Council

Amgen profit rises, shares decline  -  ‎Oct 22, 2009‎
Sales of Epogen (Epoetin alfa) increased 5% to $663 million in the third quarter of 2009 due to an increase in demand primarily from patient population ... NephrOnline

Amgen: Prolia delay further dampens expectations of hyped drug  -  ‎Oct 20, 2009‎
The US biotech has been facing a continuous decline in sales of its leading products Aranesp (darbepoetin alfa) and Epogen (epoetin alfa) and is relying on ... Trading Markets (press release)

Band-Aid Won't Stop Generic Bleeding at Johnson & Johnson  -  ‎Nov 11, 2009‎
More worrisome, the workhorse drug Procrit (epoetin alfa) is starting to look like its got a stone embedded in one hoof: this biologic, an injectable ... BNET

Amgen's Third Quarter 2009 Adjusted Earnings Per Share Increased 21 Percent to ...  -  ‎Oct 21, 2009‎
Sales of EPOGEN(®) (Epoetin alfa) increased 5 percent to $663 million in the third quarter of 2009 versus $634 million in the third quarter of 2008 due to ... Reuters

Phase 2 trail data shows Hematide increases haemoglobin & reduces blood ...  -  ‎Nov 8, 2009‎
...human erythropoietins, such as epoetin alfa or beta and darbepoetin alfa, thus suppressing the production of red blood cells by the bone marrow. ... pharmabiz.com

Heart Failure, Diabetes Attentuate Risk of High Hemoglobin  -  ‎Oct 30, 2009‎
CHOIR is a randomized trial comparing the effect of treatment with epoetin alfa to two hemoglobin targets (11.3 and 13.5 g/L) on the composite end point of ... Renal and Urology News

Amgen 3Q Profit Up 24%  -  ‎Oct 22, 2009‎
...(Epoetin alfa) increased 5 percent to $663 million in the third quarter of 2009 versus $634 million in the third quarter of 2008 due to an increase in ... The FINANCIAL

Epo-Präparat erhöht Schlaganfallrisiko  -  ‎Nov 2, 2009‎
Dort hatte der Versuch, die Ergebnisse einer Thrombolyse durch die Gabe von Epoetin alfa zu verbessern, mit einem Anstieg der Todesfälle (16 vs. ... Deutsches Ärzteblatt

Novartis' Sandoz unit gains EU approval for biosimilar epoetin alfa  -  Aug 31, 2007
ZURICH (Thomson Financial) - Novartis AG said its Sandoz unit has received European Commission approval for biosimilar epoetin alfa, for the treatment of ... Forbes

Anemia Drugs Linked to Stroke Study Deaths: FDA  -  Sep 25, 2008
The new German study looked at the use of epoetin alfa as an aid to stroke recovery. "These drugs are not licensed in the United States for this particular ... Forbes

Novartis clears EU hurdle for generic biotech drug  -  Jun 22, 2007
Epoetin alfa is marketed in Europe by Johnson & Johnson under the brand name Eprex, ... Epoetin alfa, for example, was approved by the FDA in 1989. ... MarketWatch

Ortho, Amgen Tout Anemia Drugs  -  May 15, 2005
Meanwhile, Amgen countered with data saying the final results of a study found that Aranesp administered every two weeks is as effective as epoetin alfa ... TheStreet.com - TheStreet.com (subscription)

FDA Reviewing Deaths in Anemia Drug Study  -  Sep 27, 2008
Eprex is known generically as epoetin alfa. Johnson & Johnson also sells epoetin alfa under the name Procrit. Amgen sells a version under the name Epogen. ... New York Times

Learn about Epoetin Alfa Injection from Consumer Reports Health.  -  Jan 9, 2008
All patients: Epoetin alfa increases the risk of blood clots forming in or moving to the ... Full Alert. Pending revision, the material in this section ... consumerreports.org

Sandoz Receives Positive EU Opinion For Approval Of Epoetin Alfa …  -  Jun 24, 2007
The CHMP recommendation supports the use of epoetin alfa for indications ... There can be no guarantee that epoetin alfa will be approved for sale in the EU ... Medical News Today - Medical News Today (press release)

Study Of Aranesp(R) Dosed Every Two Weeks Versus Epoetin Alfa Dosed …  -  May 22, 2006
In this study, the safety profile for both Aranesp and Epoetin alfa was consistent with the existing clinical experience for adverse events in anemic cancer ... Medical News Today - Medical News Today (press release)

… Patients Treated With PROCRIT(R) (Epoetin Alfa) Once Every Three …  -  Dec 9, 2006
Shasha, D., Dawkins, F., Wilhelm, F. "Epoetin alfa 80000 U Every Three Weeks (Q3W) in Anemic Cancer Patients Not Receiving Chemotherapy or Radiation Therapy ... Medical News Today - Medical News Today (press release)

… (R) Data Confirm Equivalent Efficacy To Epoetin Alfa In Renal...  -  Sep 8, 2008
Principal investigator of all three analyses, Professor Paul Scigalla of International Clinical Research Consulting (ICRC), commented, "These new data give ... Medical News Today - Medical News Today (press release)

PROCRIT(R) (Epoetin Alfa) Data to be Presented at American Society of...  -  Dec 6, 2007
ATLANTA, Dec. 6 /PRNewswire/ -- Data from 11 PROCRIT(R) (Epoetin alfa) studies will be presented at the American Society of Hematology (ASH) 49th Annual ... Free with registration - PR Newswire - AccessMyLibrary.com

German Trial Reports 42 Deaths in Epoetin Alfa Stroke Study  -  Sep 19, 2008
By Donna Young. The anemia drug epoetin alfa has been linked to 42 deaths in patients participating in a German clinical trial testing the drug's use as a ... BioWorld Online - BioWorld Online

High-Dose Epoetin Alfa (Procrit) Every 3 Weeks Effective for …  -  Dec 14, 2005
By Bruce Sylvester. ATLANTA, GA -- December 14, 2005 -- Epoetin alfa (Procrit) 80000 units administered every 3 weeks to patients on an every-3-week ... DG News

Treatment of Anemia in Chronic Kidney Disease  -  Dec 21, 2006
The transition from epoetin alfa to darbepoetin alfa therapy is usually uncomplicated. The approximate conversion is 200 IU of epoetin alfa to 1 mcg of ... Medscape

Controversial Anemia Drug Doesn't Cut Need for Transfusions  -  Sep 5, 2007
The drug, epoetin alfa (brand names Epogen and Procrit) has been under ... The study authors hypothesized that giving epoetin alfa would reduce the need for ... Washington Post

Cancer Therapy; Cost of epoetin alfa and darbepoetin alfa treatment...  -  Nov 22, 2005
2005 NOV 22 - (NewsRx.com) -- The cost of using epoetin alfa and darbepoetin alfa for treatment of chemotherapy-related anemia in cancer patients in Sweden ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

… Biotech Modifies Prescribing Information for PROCRIT® (Epoetin...  -  Mar 11, 2008
Ortho Biotech Products, LP today modified prescribing information for PROCRIT® (Epoetin alfa), following guidance from the US Food and Drug Administration ... webwire.com

… Committee probes EPO use, dialysis costs.(epoetin alfa)(Congress...  -  Dec 11, 2006
The drugs, mostly Amgen Inc.'s Epogen (epoetin alfa) and to a lesser extent Aranesp (darbepoetin alfa), represent CMS' largest drug expense. Pay-Per-View - BioWorld Week - Factiva, from Dow Jones

Black Box Warning Ordered for Aranesp, Epogen, and Procrit  -  Mar 9, 2007
Patients treated before surgery with epoetin alfa to reduce allogenic red ... The epoetin alfa dose was titrated to maintain a hemoglobin level of 12 to 14 ... MedPage Today

Extended dosing of darbepoetin alfa article: corrections.(Correction ...  -  Nov 1, 2005
Exceptions to this requirement are epoetin alfa and darbepoetin alfa. Drugs may be categorized into 1) drugs included in the composite rate but not ... Pay-Per-View - Nephrology Nursing Journal - HighBeam Research

Continuous Erythropoietin Receptor Activator Anti-Anemia Drug …  -  Jul 17, 2006
These included two studies using epoetin alfa/beta as a comparator and one study using darbepoetin alfa. (1,2,4). "This was the first phase 3 study for its ... DG News

… Requires Fewer Dosing Changes Than Epoetin Alfa: Presented at ASN  -  Nov 8, 2008
PHILADELPHIA -- November 8, 2008 -- Twice-monthly intravenous darbepoetin alfa requires fewer changes in dose than does epoetin alfa, causing less ... DG News

… for PROCRIT(R) (Epoetin alfa) Label Reflects Recommendations from  -  Nov 8, 2007
8 /PRNewswire-FirstCall/ -- Ortho Biotech Products, LP today modified prescribing information for PROCRIT(R) (Epoetin alfa), following guidance from the US ... Free with registration - PR Newswire - AccessMyLibrary.com

Meta-analysis evaluates the effect of epoetin alfa on left ventricular...  -  Jul 1, 2005
Researchers postulated epoetin alfa may provide survival benefits and amelioration of anemia and LVH based on the findings of a meta-analysis conducted ... National Anemia Action Council

… Cost Considerations for PROCRIT(R) (Epoetin Alfa) and Darbepoetin...  -  Oct 26, 2006
A total of 25645 hospitalizations for patients with cancer were analyzed (Epoetin alfa: 22873; darbepoetin alfa: 2772), and 66822 hospitalizations for ... RedOrbit

Single Lot of Epoetin Alfa Recalled Due to Damaged Vials  -  Aug 6, 2008
BRIDGEWATER, NJ -- August 6, 2008 -- Ortho Biotech is announcing that it is voluntarily recalling 1 manufacturing lot (P114942A) of Epoetin alfa (Procrit) ... DG News

PROCRIT(R) (Epoetin Alfa) Data to Be Presented at American Society of...  -  Nov 1, 2007
SAN FRANCISCO, Nov. 1 /PRNewswire/ -- Data from six studies of PROCRIT(R) (Epoetin alfa) will be presented at the 40th annual meeting of the American ... Free with registration - PR Newswire - AccessMyLibrary.com

Final Results of a Phase 3 European Study Demonstrate Aranesp(R) …  -  Jun 6, 2005
Amgen revolutionized Anaemia treatment with the development of recombinant erythropoietin, Epoetin alfa. Building on this heritage, Amgen developed Aranesp, ... presseportal.de

… in the prescribing information for Epoetin alfa: implications for...  -  Mar 1, 2008
Revisions in the prescribing information for Epoetin alfa: implications for ... Epoetin alfa (EPOGEN[R]) revolutionized the treatment of anemia and has been ... Pay-Per-View - Nephrology Nursing Journal - HighBeam Research

… ; Platinum-treated ovarian cancer patients managed with epoetin...  -  Jun 12, 2006
Patients were randomised 2:1 to receive epoetin alfa 10000-20000 IU three ... For the epoetin alfa group, mean Hb increased by 1.8 g/dl by weeks 4-6 and was ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones

Press Release: Updated Analysis of 2001 Epoetin Alfa Study Posted. -...  -  Dec 5, 2007
Updated Analysis of 2001 Epoetin Alfa Study Posted. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… Aranesp dosed every two weeks is comparable to Epoetin alfa dosed ...  -  May 16, 2005
..."This is the largest, randomized head-to-head comparison of darbepoetin alfa dosed every two weeks to Epoetin alfa dosed weekly, as they are most often used ... PsychCentral.com

Randomized Comparison of Epoetin Alfa (40,000 U Weekly) and …  -  Apr 3, 2006
This biased trial does nothing to advance therapeutics in this important area of supportive care. What physicians, patients, insurers want out of these two ... Gerson Lehrman Group

Press Release: PROCRIT(R) (Epoetin Alfa) Data to be Presented at …  -  Dec 6, 2007
PROCRIT(R) (Epoetin Alfa) Data to be Presented at American Society of Hematology Annual Meeting. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

EU Panel Backs Wider Approval Of Merck's Erbitux  -  Oct 24, 2008
KG, and Epoetin Alfa Hexal (epoetin alfa), from Hexal Biotech Forschungs GmbH, ... Binocrit, Abseamed and Epoetin Alfa Hexal are currently indicated in the ... Capital.gr

Chemotherapy; Epoetin alfa for treatment of cancer-related anemia …  -  Apr 25, 2005
2005 APR 25 - (NewsRx.com) -- A researcher reviews epoetin alfa for the treatment of cancer-related anemia in a recent issue of Expert Opinion on ... Pay-Per-View - Clinical Trials Week - Factiva, from Dow Jones

Study Explores Use Of PROCRIT(R) (Epoetin Alfa) Once Every Two …  -  Jun 4, 2006
New study results presented today suggest that 80000 units of PROCRIT(R) (Epoetin alfa) administered once every two weeks demonstrated comparable changes in ... Medical News Today - Medical News Today (press release)

Revised labeling for epoetin alfa (Procrit, Ortho Biotech) was issued...  -  Jan 1, 2005
Revised labeling for epoetin alfa (Procrit, Ortho Biotech) was issued advising dosing interruption and modification with patients in whom the rate of rise ... Free with registration - Formulary - AccessMyLibrary.com

Epoetin Alfa Effectively Controls Hemoglobin in Clinical Practice  -  Apr 23, 2007
April 23, 2007 — Using actual US practice patterns and dosing, epoetin alfa (Epogen; peg-EPO therapy) effectively maintains hemoglobin (Hb) levels in ... Medscape

… Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin...  -  Mar 8, 2008
Depending on the country in which Epoetin alfa is marketed, these indications may differ. Renal failure: Patients experienced greater risks for death and ... Free with registration - PR Newswire - AccessMyLibrary.com

First large study of epoetin alfa in children with cancer for anemia,...  -  Oct 1, 2006
In a large, 16 week, randomized, placebo controlled study (N=222), epoetin alfa (EPO) was given to children with non-myeloid malignancies receiving ... National Anemia Action Council

Chemotherapy; Epoetin alfa for treatment of cancer-related anemia …  -  Apr 29, 2005
2005 APR 29 - (NewsRx.com) -- A researcher reviews epoetin alfa for the treatment of cancer-related anemia in a recent issue of Expert Opinion on ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Retacrit equivalent to epoetin alfa  -  Sep 9, 2008
New data showing Retacrit corrects low haemoglobin (Hb) levels as effectively and rapidly as epoetin alfa in patients with chronic kidney disease, ... Pharmacy Europe

… Receives European Commission Approval for biosimilar epoetin alfa  -  Sep 3, 2007
This approval was indicated for the use of biosimilar epoetin alfa in treating patients with renal anemia as well as those receiving chemotherapy. ... webwire.com

Erythropoietin claims monitoring policy: implications for clinical...  -  Mar 1, 2006
When Medicare first approved reimbursement for Epoetin alfa in 1989, ... This led to low doses of Epoetin alfa and a minimal impact on outcomes. ... Pay-Per-View - Nephrology Nursing Journal - HighBeam Research

Extended dosing of darbepoetin alfa in patients with chronic kidney …  -  Jul 1, 2005
Two ESPs are currently available to treat anemia in patients with CKD: recombinant human erythropoietin (rHuEPO; Epoetin alfa) and darbepoetin alfa ... $4.95 - Nephrology Nursing Journal - ECNext

… Investigational Use Of PROCRIT® (Epoetin Alfa) Presented At...  -  Nov 8, 2008
Data from an investigational, open-label, randomized study assessing extended dosing regimens of PROCRIT® (Epoetin alfa) in treating anemia in subjects with ... Medical News Today - Medical News Today (press release)

… Reiterates Confidence in PROCRIT(R) (Epoetin alfa) Safety and...  -  Sep 11, 2007
Depending on the country in which Epoetin alfa is marketed, these indications may differ. Important US Safety Information for PROCRIT From the Boxed ... Free with registration - PR Newswire - AccessMyLibrary.com

Darbepoetin Alfa and Epoetin Alfa Use in Hospitals to Combat Anemia …  -  Oct 26, 2006
By Ed Susman. SALT LAKE CITY, UT -- October 26, 2006 -- The use of erythropoiesis-stimulating protein products among hospitalized surgical patients to ... DG News

Extended dosing of darbepoetin alfa in patients with chronic kidney …  -  Jul 1, 2005
Two ESPs are currently available to treat anemia in patients with CKD: recombinant human erythropoietin (rHuEPO; Epoetin alfa) and darbepoetin alfa ... Pay-Per-View - Nephrology Nursing Journal - HighBeam Research

FDA issues safety alerts for two cancer treatments and epoetin alfa  -  Sep 26, 2008
This week, the FDA released MedWatch alerts regarding the safety of three oncologic therapeutic agents. Chromic Phosphate P 32, erlotinib and epoetin alfa ... HemOncToday

Extended Epoetin Alfa Dosing Effects Similar in Diabetics  -  Aug 1, 2007
PATIENTS WITH and without diabetes respond similarly to extended dosing of epoetin alfa as infrequently as once every four weeks, data show. ... Renal and Urology News

Fresenius Medical Care Announces New Sourcing and Supply …  -  Oct 19, 2006
EPOGEN[R] (Epoetin alfa) is a recombinant protein with the same mechanism of action as endogenous human erythropoietin, a protein produced by the kidneys to ... Free with registration - Business Wire - AccessMyLibrary.com

Press Release: Research and Markets : Key process patents for …  -  May 3, 2005
Common conditions known to affect the response to Epoetin alfa include chronic or ... Abstract Objective: We sought to evaluate epoetin alfa drug costs in ... Pay-Per-View - M2 Presswire - HighBeam Research

… Investigational Use of PROCRIT(R) (Epoetin Alfa) Presented at...  -  Nov 7, 2008
Depending on the country in which Epoetin alfa is marketed, ... Perisurgery: PROCRIT (Epoetin alfa) increased the rate of deep venous thromboses in patients ... RedOrbit

ALFA International Corp acquires Journey of Light Inc - Deal Snapshot...  -  Jan 3, 2007
...units of Procrit (Epoetin alfa) administered once every two weeks…an exte nded initiation dose of Epoetin alfa in this patient population, was… ... Pay-Per-View - deals - Alacra Store

2006 NBA Champion Alonzo Mourning Raises Awareness About Kidney …  -  Jul 6, 2006
PROCRIT(R) (Epoetin alfa) helps treat anemia by increasing the number of red blood ... PROCRIT(R) (Epoetin alfa) is for the treatment of anemia in chronic ... Free with registration - PR Newswire - AccessMyLibrary.com

Iron deficiency in non-dialysis chronic kidney disease  -  Jun 18, 2008
Treatment was initiated with epoetin alfa 10000 U/week in the month of ... The dose of epoetin alfa was raised per protocol to 20000 U/week (Figure 1). ... Nature.com

Phase 3 Trial Starts to Evaluate the Impact of Treating Anemia with …  -  Sep 6, 2005
Amgen revolutionized anemia treatment with the development of a recombinant erythropoietin, epoetin alfa, which is currently marketed in the US by Amgen as ... Medical News Today - Medical News Today (press release)

ASN: Extended Dosing of Epoetin Alfa Appears Effective for Anemia in ...  -  Nov 7, 2008
By Todd Neale, Staff Writer, MedPage Today. PHILADELPHIA, Nov. 7 -- In chronic kidney disease, two extended dosing regimens of epoetin alfa (Procrit) worked ... MedPage Today

Press Release: PROCRIT(R) (Epoetin Alfa) Data to Be Presented at …  -  Nov 1, 2007
PROCRIT(R) (Epoetin Alfa) Data to Be Presented at American Society of Nephrology Annual Meeting. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… Biotech Revises Prescribing Information for PROCRIT(R) (Epoetin...  -  Mar 9, 2007
Located in Bridgewater, NJ, Ortho Biotech is an established market leader in Epoetin alfa therapy for anemia management. The company also markets treatments ... Free with registration - PR Newswire - AccessMyLibrary.com

… Biotech Revises Prescribing Information For PROCRIT® (Epoetin Alfa)  -  Mar 12, 2007
Ortho Biotech Products, LP, today revised the label for PROCRIT® (Epoetin alfa), acting upon guidance from the US Food and Drug Administration (FDA) to ... Medical News Today - Medical News Today (press release)

Epoetin Alfa in Critically Ill Patients  -  Oct 26, 2007
Anemia is a common acquired condition in critically ill patients, with 37% to 44% of patients requiring transfusion during their stay in the intensive care ... Medscape

… and proactive adjustments to minimize the need for holding epoetin...  -  Nov 1, 2008
...find Nephrology Nursing Journal articles. Patients who are on dialysis and receiving epoetin alfa (Epogen [R]) typically experience varying hemoglobin ... Pay-Per-View - Nephrology Nursing Journal - HighBeam Research

… Patients Treated With PROCRIT(R) (Epoetin Alfa) Once Every Three …  -  Dec 8, 2006
8 /PRNewswire/ -- New investigational study results report that 80000 units of PROCRIT(R) (Epoetin alfa) administered once every three weeks may increase ... Genetic Engineering News - Genetic Engineering News (press release)

Preliminary Data From Experimental Study Demonstrate Increased …  -  Sep 17, 2008
Epoetin alfa is marketed as EPREX(R) / ERYPO(R) outside the US by ... Epoetin alfa is a member of the class of erythropoiesis-stimulating agents (ESAs). ... RedOrbit

… Reiterates Confidence in PROCRIT(R) (Epoetin alfa) Safety and...  -  Sep 11, 2007
Ortho Biotech Reiterates Confidence in PROCRIT(R) (Epoetin alfa) Safety and Efficacy When Used According to Label. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Article: Route of administration for erythropoiesis-stimulating...  -  Sep 1, 2007
...find Nephrology Nursing Journal articles. EPoetin alfa is typically administered by the intravenous (IV) route for patients on hemodialysis and by the ... Pay-Per-View - Nephrology Nursing Journal - HighBeam Research

Article: Frequent assessment of longitudinal laboratory trends: a key...  -  Jul 1, 2007
Article: Conversion from epoetin alfa to darbepoetin alfa ... ... At this point ... same principles apply when the epoetin alfa dose is adjusted during ... Pay-Per-View - Nephrology Nursing Journal - HighBeam Research

Chronic Hemodialysis; Darbepoetin alfa treatment is safe and cost- …  -  Sep 13, 2005
..."After a recommendation from the manufacturer of epoetin alfa - that, where indicated for renal failure, epoetin alfa should be given intravenously - we ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Amgen vs. Roche: patent trial to kick off  -  Aug 29, 2007
Currently used epoetin therapies (epoetin alfa or beta) are administered one to three times weekly. The drug is already available in Austria, ... In-PharmaTechnologist.com

SCCM: Epoetin Alfa Reduces Death Risk For Critically Ill Trauma...  -  Feb 19, 2007
By Michael Smith, Senior Staff Writer, MedPage Today. ORLANDO, Feb. 19 -- In critically ill trauma patients, recombinant epoetin alfa reduces mortality by ... MedPage Today

Analysis of: Correction of Anemia with Epoetin Alfa in Chronic Kidney...  -  Nov 16, 2006
Erythropoietin (epo), whether Ortho's, Johnson & Johnson or by inference Amgen's Aranesp, can actually increase hemoglobin too much when administered to ... Gerson Lehrman Group

Erythropoietin Claims Monitoring Policy: Implications of the 2006...  -  Nov 1, 2006
The new guideline limits the cumulative monthly Epoetin alfa dose to ... In acknowledgement of variability in response to Epoetin alfa, CMS will not require ... Free with registration - Nephrology Nursing Journal - AccessMyLibrary.com

… Regimens of PROCRIT(R) (Epoetin alfa) as Maintenance Treatment fo  -  Aug 11, 2005
PROCRIT(R) (Epoetin alfa) is a prescription medication for the treatment of anemia in chronic kidney disease patients who are not on dialysis and is ... $4.95 - PR Newswire - ECNext

… Nationwide Voluntary Recall of Procrit(R) (Epoetin Alfa) Lot Number...  -  Aug 5, 2008
Ortho Biotech markets and distributes Epoetin alfa under the tradename . ... Article: FDA expands Epoetin alfa use to include AIDS ... ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Preliminary Data From Experimental Study Demonstrate …  -  Sep 17, 2008
Epoetin alfa is marketed as EPREX(R) / ERYPO(R) outside the U.S. by ... Epoetin alfa is a member of the class of erythropoiesis-stimulating agents (ESAs). ... Pay-Per-View - PR Newswire - HighBeam Research

Epoetin boosts quality of life in HIV patients.(Infectious Diseases)...  -  Feb 1, 2005
...find Internal Medicine News articles. WASHINGTON -- Treatment with 1 dose of epoetin alfa every other week maintained a normal hemoglobin level and... Pay-Per-View - Internal Medicine News - HighBeam Research

Frequent assessment of longitudinal laboratory trends: a key to …  -  Jul 1, 2007
Hb assessments and Epoetin alfa dosing practices were recorded at individual ... Trends in Hb levels in conjunction with a history of Epoetin alfa dose ... Free with registration - Nephrology Nursing Journal - AccessMyLibrary.com

Correction of Anemia to Higher Hb Levels Increases Adverse Outcome …  -  Jan 1, 2007
Use of recombinant human erythropoietin (epoetin alfa) is indicated for the ... Further, a cost benefit of using less epoetin alfa should be considered. ... National Anemia Action Council

FDA warns over deaths in German epoetin alfa stroke trial; further...  -  Oct 6, 2008
FDA warns over deaths in German epoetin alfa stroke trial; further woes for J&J. The US Food and Drug Administration has issued an early warning regarding ... $9.94 - Pharma Marketletter - Alacra Store

… Information for PROCRIT(R) (Epoetin alfa). - PR Newswire | Hig  -  Mar 9, 2007
About PROCRIT (Epoetin alfa). Read all of this article with a FREE trial. COPYRIGHT 2007 PR Newswire Association LLC. This material is published under ... Pay-Per-View - PR Newswire - HighBeam Research

Aranesp, Procrit, Epogen Linked to Risks of Pure Red Cell Aplasia, …  -  Dec 2, 2005
Darbepoetin alfa and epoetin alfa are indicated for the treatment of CRF-related anemia, and chemotherapy-related anemia in patients with nonmyeloid ... Medscape

Cost-Minimization Analysis of Darbepoetin Alpha vs Epoetin Alpha  -  Jan 3, 2006
Purpose: The cost of darbepoetin alfa versus that of epoetin alfa in a hospital setting ... Epoetin alfa is the genetically engineered form of endogenous ... Medscape

Chemotherapy; Early efficacy of epoetin alfa superior to darbepoetin...  -  Nov 22, 2005
2005 NOV 22 - (NewsRx.com) -- Epoetin alfa (EPO) is more likely than darbepoetin alfa (DARB) to produce an early response in patients with ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

… Information for PROCRIT(R) (Epoetin alfa). - PR Newswire | Hi  -  Mar 8, 2008
Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa). from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Research and Markets: Key Process Patents for …  -  May 3, 2005
Article: FDA expands Epoetin alfa use to include AIDS . ... Experience Clinical trials of Epoetin alfa were begun by Amgen in late ... doses of recombinant ... Pay-Per-View - PR Newswire - HighBeam Research

… R) Dosed Every Two Weeks versus Epoetin Alfa Dosed Weekly Published...  -  May 18, 2006
In this study, the safety profile for both Aranesp and Epoetin alfa was consistent with the existing clinical experience for adverse events in anemic cancer ... Genetic Engineering News - Genetic Engineering News (press release)

Article: Stop ESAs in nonresponders after 6-8 weeks.(Hematology)( …  -  Jan 1, 2008
Article: Conversion from epoetin alfa to darbepoetin alfa ... ... Epoetin alfa may be converted to darbepoetin alfa based on the weekly dose of epoetin ... ... Pay-Per-View - Internal Medicine News - HighBeam Research

… : Study Explores Use of PROCRIT(R) (Epoetin Alfa) Once Every Two …  -  Jun 3, 2006
Study Explores Use of PROCRIT(R) (Epoetin Alfa) Once Every Two Weeks As Initiation Treatment for Chemotherapy-Related Anemia. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

… Investigational Use of PROCRIT(R) (Epoetin alfa) Presented at...  -  Nov 7, 2008
Data From Investigational Use of PROCRIT(R) (Epoetin alfa) Presented at American Society of Nephrology Annual Meeting. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

… of Available Data Reaffirms PROCRIT(R) (Epoetin alfa) Is Safe and ...  -  Mar 11, 2008
Totality of Available Data Reaffirms PROCRIT(R) (Epoetin alfa) Is Safe and Effective When Used Appropriately as Labeled to Treat Chemotherapy-Induced ... Pay-Per-View - PR Newswire - HighBeam Research

Abstract and Introduction  -  Nov 26, 2007
Objectives: To evaluate the effect of epoetin alfa treatment on hemoglobin ... Intervention: Subcutaneous epoetin alfa or placebo weekly for 16 weeks (Phase ... Medscape

… -World Dosing and Cost Considerations for PROCRIT(R) (Epoetin Alfa)...  -  Oct 26, 2006
About PROCRIT (Epoetin alfa) PROCRIT is used for the treatment ... chemotherapy ... Article: PROCRIT(R) (Epoetin Alfa) Data to Be Presented at American ... ... Pay-Per-View - PR Newswire - HighBeam Research

Pure red cell aplasia due to follow-on epoetin  -  Jun 11, 2008
Correspondence: AK Singh, Renal Division, Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, USA. ... Nature.com

Treating Anemia Improves Fatigue and Quality of Life in Elderly: …  -  May 11, 2006
Epoetin alfa treatment was well tolerated, Dr. Agnihotri said. ... Nine of these events occurred during epoetin alfa treatment and 18 during placebo ... DG News

FDA has requested that a boxed warning be added to the prescribing …  -  Apr 1, 2007
Amgen) and epoetin alfa (Epogen, Amgen; Procrit, Ortho Biotech). ... and cautions that patients treated preoperatively with epoetin alfa to reduce ... Free with registration - Formulary - AccessMyLibrary.com

Refractory anemia in a patient with allergy to intravenous iron drugs  -  Apr 19, 2006
The weekly epoetin alfa dose had progressively been increased; most recently, ... Other potential causes of epoetin alfa resistance had been studied, ... Nature.com

FDA Safety Labeling Changes: Aranesp, Avastin, Intron A  -  Apr 6, 2005
In addition, results of a one-year randomized trial involving 939 patients with breast cancer showed that epoetin alfa therapy was associated with a higher ... Medscape

Brand Names/Synonyms:
Epoetin alfa is also known by the following brand names and/or synonymsErythropoietin precursor;Epoetin; Epogen (Amgen Inc.); Epogin (Chugai); Epomax (Elanex); Eprex (Janssen-Cilag. Ortho Biologics LLC); NeoRecormon (Roche); Recormon (Roche); Procrit (Ortho Biotech)

Drug Category:
Epoetin alfa is categorized under the following by the FDA: Antianemic Agents; hematopoietic agents (20:16.00)

Dosage Forms:
SOLUTION

Absorption:
Not Available

Interactions:
Not Available



Chemical IUPAC Name:
Human erythropoietin





Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy