Esclim

This page contains recent news articles, when available, and an overview of Esclim but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Esclim
(when available)

Pharmacology and use:
Ethinyl estradiol is a synthetic derivative of the natural estrogen estradiol. It is one of two estrogens currently used in oral contraceptive pills. The other, mestranol, is converted to ethinyl estradiol before it is biologically active. Ethinyl estradiol and norethindrone are used together as an oral contraceptive agent. For treatment of moderate to severe vasomotor symptoms associated with the menopause, female hypogonadism, prostatic carcinoma-palliative therapy of advanced disease, breast cancer, as an oral contraceptive, and as emergency contraceptive.

Mechanism Of Action:
Estrogens diffuse into their target cells and interact with a protein receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Estrogens increase the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins and suppress follicle-stimulating hormone (FSH) from the anterior pituitary. The combination of an estrogen with a progestin suppresses the hypothalamic-pituitary system, decreasing the secretion of gonadotropin-releasing hormone (GnRH).

News Articles on Ethinyl Estradiol

Bioidentical hormones have pros and cons  -  Oct 10, 2006
FDA-approved bioidentical estrogen products include pills (eg, Estrace), vaginal creams (Estrace), skin patches (eg, Alora, Climara, Esclim, Estraderm, ... San Diego Union - Tribune - San Diego Union Tribune

Southern Illinoisan : News<br>  -  Sep 19, 2006
FDA-approved bioidentical estrogen products include pills (eg, Estrace), vaginal creams (Estrace), skin patches (eg, Alora, Climara, Esclim, Estraderm, ... $2.95 - Southern Illinoisan - NewsBank

There's lots we don't know about these hormones  -  Oct 2, 2006
FDA-approved bioidentical estrogen products include pills (eg, Estrace), vaginal creams (Estrace), skin patches (eg, Alora, Climara, Esclim, Estraderm, ... Pay-Per-View - Fort Worth Star-Telegram - Factiva, from Dow Jones

Estrogen patches.(drug overview )(Drug overview)  -  Dec 1, 2005
Alora, Esclim, Estraderm, Vivelle, and Vivelle-Dot patches should be replaced twice a week; Climara once weekly. If you forget to apply a new patch when you ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Erie Times-News : News<br>  -  Feb 26, 2007
Esclim. Estraderm. Fempatch. Menostar. Vivelle/Vivelle-Dot. GELS/CREAMS. Estrasorb. EstroGel. VAGINAL CREAMS, PILLS, RINGS. Premarin Cream. Vagifem. Femring ... $2.95 - Erie Times-News - NewsBank

Article: Temis Enters Into Pact with Laboratoires Fournier - Wireless...  -  Dec 26, 2007
U.S. marketing ... to strengthen our commitment to the partnership with Laboratoires Fournier, S.A. Esclim is an important hormonal replenishment ... ... Pay-Per-View - Wireless News - HighBeam Research

Pills & Ills Bioidentical hormones lack studies  -  Sep 24, 2006
FDA-approved bioidentical estrogen products include pills (eg, Estrace), vaginal creams (Estrace), skin patches (eg, Alora, Climara, Esclim, Estraderm, ... Pay-Per-View - Charleston Gazette - Factiva, from Dow Jones

Press Release: TEMIS Text Analytics Solution to Support Laboratoires ...  -  Nov 29, 2007
U.S. marketing ... to strengthen our commitment to the partnership with Laboratoires Fournier, S.A. Esclim is an important hormonal replenishment ... ... Pay-Per-View - PR Newswire - HighBeam Research

BIOIDENTICAL HORMONES CARRY RISKS  -  Sep 14, 2006
FDA-approved bioidentical estrogen products include pills (eg, Estrace), vaginal creams (Estrace), skin patches (eg, Alora, Climara, Esclim, Estraderm, ... $2.95 - Sun Herald - NewsBank

Popular Brands of Menopause Hormones | Article from AP Online | …  -  Feb 25, 2007
Esclim. Estraderm. Fempatch. Menostar. Vivelle/Vivelle-Dot. GELS/CREAMS. Estrasorb. EstroGel. VAGINAL CREAMS, PILLS, RINGS. Premarin Cream. Vagifem. Femring ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Associated Press Archive: Glance: Popular brands of menopause …  -  Feb 25, 2007
Esclim. Estraderm. Fempatch. Menostar. Vivelle/Vivelle-Dot. GELS/CREAMS. Estrasorb. EstroGel. VAGINAL CREAMS, PILLS, RINGS. Premarin Cream. Vagifem. Femring ... $2.95 - Associated Press Archive - NewsBank

Federal Register 2006 - 71 FR 34940 Merck & Co., Inc., et al.;...  -  Jun 16, 2006
NDA 20-847 Esclim (estradiol extended- Women First Healthcare, Inc., release film) Transdermal 380 Lexington Ave., New York, System NY 10168 ... Pay-Per-View - Federal Register 2006 - Loislaw

QUESTION & ANSWER FROM THE PHARMACY / LONG-TERM …  -  Sep 18, 2006
FDA-approved bioidentical estrogen products include pills (eg, Estrace), vaginal creams (Estrace), skin patches (eg, Alora, Climara, Esclim, Estraderm, ... $2.95 - Press of Atlantic City, The - NewsBank

«The Forbes»: рейтинг брÑ?ндированных препаратов длÑ? ЗГТ на рынке …  -  Mar 19, 2007
CombiPatch, Esclim, Estraderm, Fempatch, Menostar, Vivelle/Vivelle-Dot; Ñ?реди лекарÑ?твенных Ñ?редÑ?тв в форме гелÑ? или крема — Estrasorb и EstroGel; ... Ð?птека online

Brand Names/Synonyms:
Esclim is also known by the following brand names and/or synonyms17?-Ethynylestradiol; 17alpha-Ethinylestradiol; 17alpha-Ethynylestradiol; 17alpha-Ethynyloestradiol; Aethinyloestradiolum; Aethinyoestradiol [German]; Alesse; Alora; Amenoron; Amenorone; Anovlar; BRN 2419975; Binovum; Brevicon; Brevinor; CCRIS 286; CHEMBANK1139; Climara; Conceplan; Cyclosa; Demulen; Desogen; Dicromil; Diognat-E; Diogyn E; Diogyn-E; Diprol; Dyloform; EE; EE2; EO; ETHINYLESTRADIOL; Ertonyl; Esclim; Esteed; Estigyn; Estinyl; Eston-E; Estopherol; Estoral; Estoral {[Orion]}; Estorals; Estrace; Estraderm; Estradiol; Estring; Estrogel; Estrogen; Ethidol; Ethinoral; Ethinyl Estradiol; Ethinyl-Oestranol; Ethinylestradiolum [Inn-Latin]; Ethinylestriol; Ethinyloestradiol; Ethy 11; Ethynylestradiol; Ethynyloestradiol; Eticyclin; Eticyclol; Eticylol; Etinestrol; Etinestryl; Etinilestradiol [Inn-Spanish]; Etinilestradiolo [Dcit]; Etinoestryl; Etistradiol; Etivex; Feminone; Fempatch; Follicoral; Genora; Ginestrene; Gynodiol; Gynolett; HSDB 3587; Halodrin; Inestra; Innofem; Jenest; Kolpolyn; Levlen; Linoral; Lo/Ovral; Loestrin; Logynon; Lynoral; Marvelon; Menolyn; Menostar; Mercilon; Microfollin; Microgynon; Mircette; Modicon; NEE; NSC-10973; Necon; Nelova; Neo-Estrone; Neocon; Nogest-S; Norcept; Nordette; Norethin 1/35 E; Norimin; Norinyl; Norlestrin; Novestrol; Oradiol; Orestralyn; Orestrayln; Ortho Tri-Cyclen; Ortho-Cept; Ortho-Cyclen; Ortho-Novum; Ovcon; Ovex; Oviol; Ovral; Ovran; Ovranette; Ovysmen; Palonyl; Perovex; Primogyn; Primogyn C; Primogyn M; Progynon C; Progynon M; Prosexol; Spanestrin; Stediril; Synphase; Tetragynon; Thiuram E; Thiuranide; Tri-Levlen; Tri-Norinyl; Trinordiol; Trinovum; Triphasil; Vagifem; Varnoline; Vivelle; Ylestrol

Drug Category:
Esclim is categorized under the following by the FDA: Estrogens; ATC:G03CA01

Dosage Forms:
DISC (SUSTAINED-RELEASE); GEL; IMPLANT; LIQUID; PATCH; RING (SLOW-RELEASE); SOLUTION; TABLET

Absorption:
Rapid and complete absorption follows oral intake of ethinyl estradiol (bioavailability 43%).

Interactions:
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Chemical IUPAC Name:
17-ethynyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol





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